{"id":10010,"date":"2026-11-10T13:14:44","date_gmt":"2026-11-10T04:14:44","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=10010"},"modified":"2026-11-10T13:14:45","modified_gmt":"2026-11-10T04:14:45","slug":"lovas-trial-anca-vasculitis-rituximab-reduced-glucocorticoids","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/lovas-trial-anca-vasculitis-rituximab-reduced-glucocorticoids\/","title":{"rendered":"LoVAS\u8a66\u9a13\uff5cANCA\u95a2\u9023\u8840\u7ba1\u708e\u306b\u5bfe\u3059\u308b\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7642\u6cd5\u3068\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u306e\u52b9\u679c\u30fb\u5b89\u5168\u6027"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">ANCA\u95a2\u9023\u8840\u7ba1\u708e\uff08ANCA-associated vasculitis\uff1aAAV\uff09\u306f\u3001\u814e\u81d3\u3001\u80ba\u3001\u672b\u68a2\u795e\u7d4c\u306a\u3069\u306b\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3059\u5168\u8eab\u6027\u306e\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5bdb\u89e3\u5c0e\u5165\u7642\u6cd5\u3067\u306f\u3001\u5f93\u6765\u3001\u9ad8\u7528\u91cf\u306e\u526f\u814e\u76ae\u8cea\u30b9\u30c6\u30ed\u30a4\u30c9\u3068\u514d\u75ab\u6291\u5236\u85ac\u3092\u4f75\u7528\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306b\u3088\u308b\u611f\u67d3\u75c7\u3084\u7cd6\u5c3f\u75c5\u3001\u9aa8\u7c97\u9b06\u75c7\u306a\u3069\u306e\u6709\u5bb3\u4e8b\u8c61\u306f\u3001\u7279\u306b\u9ad8\u9f62\u60a3\u8005\u3067\u5927\u304d\u306a\u554f\u984c\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2021\u5e74\u306bJAMA\u8a8c\u306b\u767a\u8868\u3055\u308c\u305f\u65e5\u672c\u767a\u306eLoVAS\u8a66\u9a13\u306f\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u521d\u671f\u6295\u4e0e\u91cf\u3092\u5f93\u6765\u306e\u534a\u5206\u306b\u6e1b\u3089\u3057\u3066\u3082\u5bdb\u89e3\u5c0e\u5165\u52b9\u679c\u3092\u7dad\u6301\u3067\u304d\u308b\u304b\u3092\u691c\u8a3c\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u8a18\u4e8b\u3067\u306f\u3001LoVAS\u8a66\u9a13\u306e\u4e3b\u8981\u7d50\u679c\u30012024\u5e74\u306b\u5831\u544a\u3055\u308c\u305f2\u5e74\u9593\u8ffd\u8de1\u7814\u7a76\u3001PEXIVAS\u8a66\u9a13\u3068\u306e\u9055\u3044\u3092\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u30012026\u5e74\u306b\u6b63\u5f0f\u64a4\u56de\u3055\u308c\u305fADVOCATE\u8a66\u9a13\u306b\u3064\u3044\u3066\u3082\u3001\u73fe\u5728\u306e\u77e5\u898b\u3092\u8e0f\u307e\u3048\u3066\u6574\u7406\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c1\u7ae0\uff0eLoVAS\u8a66\u9a13\u3068\u306f\u3069\u306e\u3088\u3046\u306a\u7814\u7a76\u304b\uff1f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\uff08Low-dose Glucocorticoid Vasculitis Induction Study\uff09\u306f\u3001\u65e5\u672c\u306e21\u65bd\u8a2d\u3067\u5b9f\u65bd\u3055\u308c\u305f\u3001\u591a\u65bd\u8a2d\u5171\u540c\u3001\u975e\u76f2\u691c\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u975e\u52a3\u6027\u8a66\u9a13\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2014\u5e7411\u6708\u304b\u30892019\u5e746\u6708\u306b\u304b\u3051\u3066\u3001\u65b0\u898f\u8a3a\u65ad\u306eANCA\u95a2\u9023\u8840\u7ba1\u708e\u60a3\u8005140\u4eba\u304c\u767b\u9332\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u60a3\u8005\u306e\u5e74\u9f62\u4e2d\u592e\u5024\u306f73\u6b73\u3067\u3001\u65e5\u672c\u306e\u9ad8\u9f62AAV\u60a3\u8005\u306e\u8a3a\u7642\u3092\u8003\u3048\u308b\u3046\u3048\u3067\u91cd\u8981\u306a\u7814\u7a76\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5bfe\u8c61\u75be\u60a3\u306b\u306f\u3001\u4e3b\u306b\u9855\u5fae\u93e1\u7684\u591a\u767a\u8840\u7ba1\u708e\uff08MPA\uff09\u3001\u591a\u767a\u8840\u7ba1\u708e\u6027\u8089\u82bd\u816b\u75c7\uff08GPA\uff09\u3001\u814e\u9650\u5c40\u578b\u8840\u7ba1\u708e\u304c\u542b\u307e\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u91cd\u75c7\u7cf8\u7403\u4f53\u814e\u708e\u3084\u91cd\u75c7\u80ba\u80de\u51fa\u8840\u3092\u4f34\u3046\u60a3\u8005\u306f\u9664\u5916\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6cbb\u7642\u7fa4\u306e\u8a2d\u5b9a<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u60a3\u8005\u306f\u6b21\u306e2\u7fa4\u306b\u7121\u4f5c\u70ba\u5316\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4\uff0870\u4eba\uff09<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30d7\u30ec\u30c9\u30cb\u30be\u30ed\u30f3\uff08PSL\uff09\u521d\u671f\u6295\u4e0e\u91cf\uff1a0.5 mg\/kg\/\u65e5<\/li>\n\n\n\n<li>\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\uff1a375 mg\/m\u00b2\u3092\u90311\u56de\u3001\u8a084\u56de<\/li>\n\n\n\n<li>\u539f\u5247\u3068\u3057\u3066\u7d045\u304b\u6708\u3067PSL\u4e2d\u6b62\u3092\u76ee\u6307\u3059<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6a19\u6e96\u91cf\u7fa4\uff0870\u4eba\uff09<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>PSL\u521d\u671f\u6295\u4e0e\u91cf\uff1a1.0 mg\/kg\/\u65e5<\/li>\n\n\n\n<li>\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\uff1a375 mg\/m\u00b2\u3092\u90311\u56de\u3001\u8a084\u56de<\/li>\n\n\n\n<li>6\u304b\u6708\u6642\u70b9\u3067PSL 10 mg\/\u65e5\u307e\u3067\u6e1b\u91cf<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e21\u7fa4\u3068\u3082\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u5358\u72ec\u7642\u6cd5\u306e\u6e1b\u91cf\u3092\u691c\u8a3c\u3057\u305f\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u306b\u3088\u308b\u5bdb\u89e3\u5c0e\u5165\u7642\u6cd5\u3092\u524d\u63d0\u3068\u3057\u3066\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u521d\u671f\u6295\u4e0e\u91cf\u3068\u7d2f\u7a4d\u66dd\u9732\u91cf\u3092\u6e1b\u3089\u305b\u308b\u304b\u3092\u691c\u8a0e\u3057\u305f\u7814\u7a76\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f\u30016\u304b\u6708\u6642\u70b9\u306b\u304a\u3051\u308b\u30d7\u30ed\u30c8\u30b3\u30eb\u898f\u5b9a\u306e\u5bdb\u89e3\u5c0e\u5165\u7387\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e8b\u524d\u306b\u8a2d\u5b9a\u3055\u308c\u305f\u975e\u52a3\u6027\u30de\u30fc\u30b8\u30f3\u306f\u3001\u7d76\u5bfe\u5dee\u221220\u30d1\u30fc\u30bb\u30f3\u30c8\u30dd\u30a4\u30f3\u30c8\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-49-480x600.png\" alt=\"LoVAS\u8a66\u9a13\u306e\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u3002ANCA\u95a2\u9023\u8840\u7ba1\u708e140\u4eba\u3092\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4\u3068\u6a19\u6e96\u91cf\u7fa4\u306b\u5272\u308a\u4ed8\u3051\u3001\u4e21\u7fa4\u306b\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3092\u4f75\u7528\u3057\u305f\u3002\" class=\"wp-image-10012\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-49-480x600.png 480w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-49-240x300.png 240w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-49-767x959.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-49.png 800w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1aLoVAS\u8a66\u9a13\u306e\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u3002\u65b0\u898f\u8a3a\u65ad\u306eANCA\u95a2\u9023\u8840\u7ba1\u708e\u60a3\u8005140\u4eba\u3092\u3001\u521d\u671fPSL 0.5 mg\/kg\/\u65e5\u306e\u6e1b\u91cf\u7fa470\u4eba\u3068\u30011.0 mg\/kg\/\u65e5\u306e\u6a19\u6e96\u91cf\u7fa470\u4eba\u306b\u7121\u4f5c\u70ba\u5316\u3057\u305f\u3002\u4e21\u7fa4\u306b\u30ea\u30c4\u30ad\u30b7\u30de\u30d6375 mg\/m\u00b2\u3092\u90311\u56de\u3001\u8a084\u56de\u6295\u4e0e\u3057\u305f\u3002\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f6\u304b\u6708\u6642\u70b9\u306e\u5bdb\u89e3\u5c0e\u5165\u7387\u3068\u3057\u305f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c2\u7ae0\uff0e\u4e3b\u8981\u7d50\u679c\uff1a\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4\u306f\u975e\u52a3\u6027\u3092\u9054\u6210<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">6\u304b\u6708\u6642\u70b9\u306e\u5bdb\u89e3\u5c0e\u5165\u7387\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">71.0\uff05\uff0849\/69\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6a19\u6e96\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">69.2\uff05\uff0845\/65\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7fa4\u9593\u5dee\u306f\uff0b1.8\u30d1\u30fc\u30bb\u30f3\u30c8\u30dd\u30a4\u30f3\u30c8\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7247\u507497.5\uff05\u4fe1\u983c\u533a\u9593\u306e\u4e0b\u9650\u306f\u221213.7\u30d1\u30fc\u30bb\u30f3\u30c8\u30dd\u30a4\u30f3\u30c8\u3067\u3042\u308a\u3001\u4e8b\u524d\u306b\u8a2d\u5b9a\u3055\u308c\u305f\u975e\u52a3\u6027\u30de\u30fc\u30b8\u30f3\u221220\u30dd\u30a4\u30f3\u30c8\u3092\u4e0a\u56de\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u975e\u52a3\u6027\u691c\u5b9a\u306ep\u5024\u306f0.003\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001LoVAS\u8a66\u9a13\u3067\u306f\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u4f75\u7528\u4e0b\u306e\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7642\u6cd5\u304c\u30016\u304b\u6708\u5bdb\u89e3\u5c0e\u5165\u7387\u306b\u3064\u3044\u3066\u6a19\u6e96\u91cf\u7642\u6cd5\u306b\u5bfe\u3059\u308b\u975e\u52a3\u6027\u3092\u9054\u6210\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-50-480x600.png\" alt=\"LoVAS\u8a66\u9a13\u306e6\u304b\u6708\u5bdb\u89e3\u5c0e\u5165\u7387\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa471.0\uff05\u3001\u6a19\u6e96\u91cf\u7fa469.2\uff05\u3067\u3001\u975e\u52a3\u6027\u3092\u9054\u6210\u3057\u305f\u3002\" class=\"wp-image-10013\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-50-480x600.png 480w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-50-240x300.png 240w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-50-767x959.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-50.png 800w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1aLoVAS\u8a66\u9a13\u306b\u304a\u3051\u308b6\u304b\u6708\u5bdb\u89e3\u5c0e\u5165\u7387\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4\u3067\u306f49\/69\u4eba\uff0871.0\uff05\uff09\u3001\u6a19\u6e96\u91cf\u7fa4\u3067\u306f45\/65\u4eba\uff0869.2\uff05\uff09\u304c\u5bdb\u89e3\u3092\u9054\u6210\u3057\u305f\u3002\u7fa4\u9593\u5dee\u306f\uff0b1.8\u30d1\u30fc\u30bb\u30f3\u30c8\u30dd\u30a4\u30f3\u30c8\u3067\u3042\u308a\u3001\u7247\u507497.5\uff05\u4fe1\u983c\u533a\u9593\u306e\u4e0b\u9650\u306f\u221213.7\u30dd\u30a4\u30f3\u30c8\u3067\u3042\u3063\u305f\u3002\u4e8b\u524d\u898f\u5b9a\u3055\u308c\u305f\u975e\u52a3\u6027\u30de\u30fc\u30b8\u30f3\u221220\u30dd\u30a4\u30f3\u30c8\u3092\u4e0a\u56de\u308a\u3001\u975e\u52a3\u6027\u304c\u793a\u3055\u308c\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u975e\u52a3\u6027\u306f\u300c\u5b8c\u5168\u306b\u540c\u3058\u52b9\u679c\u300d\u3092\u610f\u5473\u3057\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3053\u3067\u6ce8\u610f\u3057\u305f\u3044\u306e\u306f\u3001\u975e\u52a3\u6027\u8a66\u9a13\u306e\u89e3\u91c8\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u975e\u52a3\u6027\u304c\u793a\u3055\u308c\u305f\u3053\u3068\u306f\u30012\u3064\u306e\u6cbb\u7642\u6cd5\u306e\u52b9\u679c\u304c\u5b8c\u5168\u306b\u540c\u4e00\u3067\u3042\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u306e\u975e\u52a3\u6027\u30de\u30fc\u30b8\u30f3\u306f20\u30d1\u30fc\u30bb\u30f3\u30c8\u30dd\u30a4\u30f3\u30c8\u3068\u6bd4\u8f03\u7684\u5927\u304d\u304f\u8a2d\u5b9a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u7d50\u679c\u306f\u300c\u4e00\u5b9a\u306e\u8a31\u5bb9\u7bc4\u56f2\u5185\u3067\u6a19\u6e96\u6cbb\u7642\u3088\u308a\u52a3\u3089\u306a\u3044\u3053\u3068\u3092\u793a\u3057\u305f\u300d\u3068\u7406\u89e3\u3059\u3079\u304d\u3067\u3042\u308a\u3001\u3042\u3089\u3086\u308b\u60a3\u8005\u3067\u6cbb\u7642\u52b9\u679c\u304c\u540c\u7b49\u3067\u3042\u308b\u3068\u65ad\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c3\u7ae0\uff0e\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u306b\u3088\u3063\u3066\u91cd\u7be4\u306a\u611f\u67d3\u75c7\u304c\u6e1b\u5c11<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u3067\u91cd\u8981\u306a\u306e\u306f\u3001\u5bdb\u89e3\u5c0e\u5165\u7387\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4\u3067\u306f\u3001\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u3068\u91cd\u7be4\u306a\u611f\u67d3\u75c7\u304c\u6709\u610f\u306b\u5c11\u306a\u3044\u7d50\u679c\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">18.8\uff05\uff0813\/69\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6a19\u6e96\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">36.9\uff05\uff0824\/65\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d76\u5bfe\u5dee\uff1a\u221218.1\u30d1\u30fc\u30bb\u30f3\u30c8\u30dd\u30a4\u30f3\u30c8<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">p\uff1d0.02<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u91cd\u7be4\u306a\u611f\u67d3\u75c7<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">7.2\uff05\uff085\/69\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6a19\u6e96\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">20.0\uff05\uff0813\/65\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d76\u5bfe\u5dee\uff1a\u221212.8\u30d1\u30fc\u30bb\u30f3\u30c8\u30dd\u30a4\u30f3\u30c8<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">p\uff1d0.04<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3044\u305a\u308c\u3082\u6e1b\u91cf\u7fa4\u3067\u6709\u610f\u306b\u5c11\u306a\u3044\u7d50\u679c\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-51-480x600.png\" alt=\"LoVAS\u8a66\u9a13\u306e\u5b89\u5168\u6027\u6bd4\u8f03\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4\u3067\u306f\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c6118.8\uff05\u3001\u91cd\u7be4\u306a\u611f\u67d3\u75c77.2\uff05\u3067\u3001\u6a19\u6e96\u91cf\u7fa4\u3088\u308a\u5c11\u306a\u304b\u3063\u305f\u3002\" class=\"wp-image-10014\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-51-480x600.png 480w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-51-240x300.png 240w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-51-767x959.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-51.png 800w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1aLoVAS\u8a66\u9a13\u306e6\u304b\u6708\u9593\u306b\u304a\u3051\u308b\u5b89\u5168\u6027\u306e\u6bd4\u8f03\u3002\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u3092\u7d4c\u9a13\u3057\u305f\u60a3\u8005\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa418.8\uff05\u3001\u6a19\u6e96\u91cf\u7fa436.9\uff05\u3067\u3042\u3063\u305f\u3002\u91cd\u7be4\u306a\u611f\u67d3\u75c7\u3092\u7d4c\u9a13\u3057\u305f\u60a3\u8005\u306f\u3001\u305d\u308c\u305e\u308c7.2\uff05\u300120.0\uff05\u3067\u3042\u308a\u3001\u3044\u305a\u308c\u3082\u6e1b\u91cf\u7fa4\u3067\u6709\u610f\u306b\u5c11\u306a\u304b\u3063\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u81e8\u5e8a\u7684\u610f\u7fa9<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">AAV\u60a3\u8005\u3067\u306f\u3001\u539f\u75be\u60a3\u306b\u3088\u308b\u81d3\u5668\u969c\u5bb3\u3060\u3051\u3067\u306a\u304f\u3001\u6cbb\u7642\u306b\u4f34\u3046\u611f\u67d3\u75c7\u3082\u91cd\u8981\u306a\u4e88\u5f8c\u898f\u5b9a\u56e0\u5b50\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u9ad8\u9f62\u8005\u3067\u306f\u3001\u9ad8\u7528\u91cf\u30b9\u30c6\u30ed\u30a4\u30c9\u306b\u3088\u308b\u514d\u75ab\u6291\u5236\u3001\u7b4b\u529b\u4f4e\u4e0b\u3001\u7cd6\u4ee3\u8b1d\u7570\u5e38\u3001\u9aa8\u7c97\u9b06\u75c7\u306a\u3069\u304c\u6cbb\u7642\u7d99\u7d9a\u306b\u5f71\u97ff\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u306f\u3001\u75be\u60a3\u5236\u5fa1\u3092\u7dad\u6301\u3057\u306a\u304c\u3089\u30b9\u30c6\u30ed\u30a4\u30c9\u66dd\u9732\u91cf\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u3001\u6cbb\u7642\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\u306e\u8efd\u6e1b\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u6e1b\u91cf\u7fa4\u3067\u3082\u91cd\u7be4\u306a\u611f\u67d3\u75c7\u306f\u767a\u751f\u3057\u3066\u304a\u308a\u3001\u611f\u67d3\u75c7\u4e88\u9632\u3084\u7d99\u7d9a\u7684\u306a\u5b89\u5168\u6027\u8a55\u4fa1\u304c\u4e0d\u8981\u306b\u306a\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c4\u7ae0\uff0e2\u5e74\u9593\u8ffd\u8de1\u7814\u7a76\uff1a\u30b9\u30c6\u30ed\u30a4\u30c9\u4e2d\u6b62\u3068\u518d\u71c3\u7387<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u3067\u306f\u30016\u304b\u6708\u9593\u306e\u5bdb\u89e3\u5c0e\u5165\u671f\u306b\u7d9a\u304d\u300118\u304b\u6708\u9593\u306e\u5bdb\u89e3\u7dad\u6301\u671f\u3092\u542b\u308024\u304b\u6708\u9593\u306e\u8ffd\u8de1\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u4e8b\u524d\u898f\u5b9a\u3055\u308c\u305f\u8ffd\u8de1\u7814\u7a76\u306f\u30012024\u5e74\u306eAnnals of the Rheumatic Diseases\u8a8c\u306b\u767a\u8868\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5bdb\u89e3\u9054\u6210\u5f8c\u306b\u306f\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u306b\u3088\u308b\u7dad\u6301\u7642\u6cd5\u304c\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u30b9\u30c6\u30ed\u30a4\u30c9\u4e2d\u6b62\u5272\u5408<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d7\u30ed\u30c8\u30b3\u30eb\u306b\u6cbf\u3063\u3066\u5bdb\u89e3\u3092\u9054\u6210\u3057\u305f\u60a3\u8005\u306e\u3046\u3061\u3001PSL\u3092\u4e2d\u6b62\u3067\u304d\u305f\u5272\u5408\u306f\u6b21\u306e\u901a\u308a\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">89.7\uff05<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">PSL\u4e2d\u6b62\u307e\u3067\u306e\u671f\u9593\u4e2d\u592e\u5024\uff1a150\u65e5<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6a19\u6e96\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">15.5\uff05<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">PSL\u4e2d\u6b62\u307e\u3067\u306e\u671f\u9593\u4e2d\u592e\u5024\uff1a375\u65e5<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6e1b\u91cf\u7fa4\u3067\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u4e2d\u6b62\u3067\u304d\u305f\u60a3\u8005\u304c\u591a\u304f\u3001\u4e2d\u6b62\u307e\u3067\u306e\u671f\u9593\u3082\u77ed\u3044\u7d50\u679c\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-52-480x600.png\" alt=\"LoVAS\u8a66\u9a13\u306ePSL\u4e2d\u6b62\u72b6\u6cc1\u3002\u6e1b\u91cf\u7fa4\u306e\u4e2d\u6b62\u5272\u540889.7\uff05\u3001\u6a19\u6e96\u91cf\u7fa415.5\uff05\u3002\u4e2d\u6b62\u307e\u3067\u306e\u671f\u9593\u4e2d\u592e\u5024\u306f150\u65e5\u3068375\u65e5\u3002\" class=\"wp-image-10015\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-52-480x600.png 480w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-52-240x300.png 240w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-52-767x959.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-52.png 800w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1aLoVAS\u8a66\u9a13\u306e2\u5e74\u9593\u8ffd\u8de1\u7814\u7a76\u306b\u304a\u3051\u308bPSL\u4e2d\u6b62\u72b6\u6cc1\u3002\u30d7\u30ed\u30c8\u30b3\u30eb\u306b\u6cbf\u3063\u3066\u5bdb\u89e3\u3092\u9054\u6210\u3057\u305f\u60a3\u8005\u306e\u3046\u3061\u3001PSL\u3092\u4e2d\u6b62\u3057\u305f\u5272\u5408\u306f\u6e1b\u91cf\u7fa489.7\uff05\u3001\u6a19\u6e96\u91cf\u7fa415.5\uff05\u3067\u3042\u3063\u305f\u3002\u4e2d\u6b62\u307e\u3067\u306e\u671f\u9593\u4e2d\u592e\u5024\u306f\u3001\u305d\u308c\u305e\u308c150\u65e5\u3001375\u65e5\u3067\u3042\u3063\u305f\u3002\u4e21\u7fa4\u3067\u30b9\u30c6\u30ed\u30a4\u30c9\u4e2d\u6b62\u306b\u95a2\u3059\u308b\u6cbb\u7642\u30d7\u30ed\u30c8\u30b3\u30eb\u304c\u7570\u306a\u308b\u3053\u3068\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u4e21\u7fa4\u306e\u6cbb\u7642\u30d7\u30ed\u30c8\u30b3\u30eb\u3067\u306f\u30b9\u30c6\u30ed\u30a4\u30c9\u4e2d\u6b62\u306e\u76ee\u6a19\u6642\u671f\u304c\u7570\u306a\u3063\u3066\u3044\u305f\u305f\u3081\u3001\u3053\u306e\u7d50\u679c\u306f\u6cbb\u7642\u8a2d\u8a08\u306e\u9055\u3044\u3082\u53cd\u6620\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u6e1b\u91cf\u7fa4\u3067\u3082\u75be\u60a3\u6d3b\u52d5\u6027\u304c\u6b8b\u5b58\u3057\u3066\u3044\u308b\u3068\u5224\u65ad\u3055\u308c\u305f\u5834\u5408\u306b\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u4e2d\u6b62\u6bb5\u968e\u3078\u306e\u79fb\u884c\u3092\u5ef6\u671f\u3067\u304d\u308b\u898f\u5b9a\u304c\u8a2d\u3051\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3059\u3079\u3066\u306e\u60a3\u8005\u306b\u4e00\u5f8b\u306e\u901f\u5ea6\u3067\u30b9\u30c6\u30ed\u30a4\u30c9\u4e2d\u6b62\u3092\u5f37\u5236\u3057\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">24\u304b\u6708\u9593\u306e\u518d\u71c3\u7387<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u518d\u71c3\u7387\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">13.0\uff05\uff089\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6a19\u6e96\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">7.6\uff05\uff085\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">p\uff1d0.311<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u306a\u5dee\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u8981\u518d\u71c3\u306f\u4e21\u7fa4\u3068\u30822\u4eba\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u6570\u5024\u4e0a\u306f\u6e1b\u91cf\u7fa4\u3067\u518d\u71c3\u304c\u591a\u304f\u3001\u8a66\u9a13\u898f\u6a21\u3082\u6bd4\u8f03\u7684\u5c0f\u3055\u3044\u305f\u3081\u3001\u9577\u671f\u518d\u71c3\u7387\u304c\u5b8c\u5168\u306b\u540c\u7b49\u3067\u3042\u308b\u3068\u7d50\u8ad6\u3065\u3051\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">24\u304b\u6708\u9593\u306e\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u3092\u7d4c\u9a13\u3057\u305f\u60a3\u8005\u306f\u6b21\u306e\u901a\u308a\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">27.5\uff05\uff0819\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6a19\u6e96\u91cf\u7fa4<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">46.2\uff05\uff0830\u4eba\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">p\uff1d0.025<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">24\u304b\u6708\u9593\u3092\u901a\u3058\u3066\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4\u3067\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u304c\u6709\u610f\u306b\u5c11\u306a\u3044\u7d50\u679c\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u306e\u5dee\u306f\u4e3b\u3068\u3057\u3066\u6700\u521d\u306e6\u304b\u6708\u9593\u306e\u5bdb\u89e3\u5c0e\u5165\u671f\u306b\u767a\u751f\u3057\u305f\u6709\u5bb3\u4e8b\u8c61\u306e\u6e1b\u5c11\u306b\u3088\u308b\u3082\u306e\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b7b\u4ea1\u306f\u6e1b\u91cf\u7fa42\u4eba\u3001\u6a19\u6e96\u91cf\u7fa45\u4eba\u3067\u3057\u305f\u304c\u3001\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u306a\u5dee\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u9577\u671f\u8ffd\u8de1\u304b\u3089\u4f55\u304c\u308f\u304b\u3063\u305f\u306e\u304b\uff1f<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u306e2\u5e74\u9593\u8ffd\u8de1\u7814\u7a76\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7642\u6cd5\u304c\u65e9\u671f\u306e\u30b9\u30c6\u30ed\u30a4\u30c9\u96e2\u8131\u3092\u53ef\u80fd\u306b\u3057\u3001\u6cbb\u7642\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\u3092\u6e1b\u3089\u3059\u53ef\u80fd\u6027\u3092\u652f\u6301\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u9577\u671f\u7684\u306a\u518d\u71c3\u30ea\u30b9\u30af\u3084\u751f\u547d\u4e88\u5f8c\u306b\u95a2\u3059\u308b\u660e\u78ba\u306a\u512a\u8d8a\u6027\u304c\u8a3c\u660e\u3055\u308c\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c5\u7ae0\uff0eLoVAS\u8a66\u9a13\u3068PEXIVAS\u8a66\u9a13\u306e\u9055\u3044<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u3068PEXIVAS\u8a66\u9a13\u306f\u3001\u3069\u3061\u3089\u3082ANCA\u95a2\u9023\u8840\u7ba1\u708e\u306b\u304a\u3051\u308b\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u306e\u6839\u62e0\u3068\u306a\u308b\u91cd\u8981\u306a\u7814\u7a76\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u5bfe\u8c61\u60a3\u8005\u3084\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u6e1b\u3089\u3057\u65b9\u306b\u306f\u9055\u3044\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">LoVAS\u8a66\u9a13<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5bfe\u8c61\u60a3\u8005<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65b0\u898f\u8a3a\u65ad\u306eAAV\u60a3\u8005\u3002\u91cd\u75c7\u814e\u969c\u5bb3\u3084\u91cd\u75c7\u80ba\u80de\u51fa\u8840\u306e\u60a3\u8005\u306f\u9664\u5916\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u65b9\u6cd5<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u521d\u671fPSL\u6295\u4e0e\u91cf\u30920.5 mg\/kg\/\u65e5\u306b\u8a2d\u5b9a\u3057\u3001\u6a19\u6e96\u91cf1.0 mg\/kg\/\u65e5\u3068\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4f75\u7528\u3059\u308b\u514d\u75ab\u6291\u5236\u7642\u6cd5<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e21\u7fa4\u3068\u3082\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3092\u4f7f\u7528\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">6\u304b\u6708\u6642\u70b9\u306e\u5bdb\u89e3\u5c0e\u5165\u7387\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">PEXIVAS\u8a66\u9a13<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5bfe\u8c61\u60a3\u8005<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">eGFR 50 mL\/min\/1.73 m\u00b2\u672a\u6e80\u306e\u814e\u969c\u5bb3\u3001\u307e\u305f\u306f\u3073\u307e\u3093\u6027\u80ba\u80de\u51fa\u8840\u3092\u4f34\u3046\u91cd\u75c7AAV\u60a3\u8005\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u65b9\u6cd5<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u521d\u671f\u306b\u9ad8\u7528\u91cf\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u7528\u3044\u3001\u305d\u306e\u5f8c\u306e\u6f38\u6e1b\u901f\u5ea6\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4f75\u7528\u3059\u308b\u514d\u75ab\u6291\u5236\u7642\u6cd5<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u307e\u305f\u306f\u30b7\u30af\u30ed\u30db\u30b9\u30d5\u30a1\u30df\u30c9\u3092\u4f7f\u7528\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b7b\u4ea1\u307e\u305f\u306f\u672b\u671f\u814e\u4e0d\u5168\u306e\u8907\u5408\u8a55\u4fa1\u9805\u76ee\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u4e21\u8a66\u9a13\u306e\u81e8\u5e8a\u7684\u4f4d\u7f6e\u3065\u3051<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u306f\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u4f75\u7528\u4e0b\u3067\u306e\u521d\u671f\u30b9\u30c6\u30ed\u30a4\u30c9\u6295\u4e0e\u91cf\u306e\u6e1b\u91cf\u3092\u691c\u8a3c\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001PEXIVAS\u8a66\u9a13\u306f\u3001\u91cd\u75c7AAV\u60a3\u8005\u306b\u304a\u3051\u308b\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u6025\u901f\u6f38\u6e1b\u3092\u691c\u8a3c\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3064\u307e\u308a\u3001\u4e21\u8a66\u9a13\u306f\u540c\u3058\u6cbb\u7642\u65b9\u6cd5\u3092\u6bd4\u8f03\u3057\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7570\u306a\u308b\u60a3\u8005\u96c6\u56e3\u3068\u6cbb\u7642\u6226\u7565\u3092\u8a55\u4fa1\u3057\u3066\u304a\u308a\u3001\u76f8\u88dc\u7684\u306b\u89e3\u91c8\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-53-480x600.png\" alt=\"LoVAS\u8a66\u9a13\u3068PEXIVAS\u8a66\u9a13\u306e\u6bd4\u8f03\u3002LoVAS\u306f\u30b9\u30c6\u30ed\u30a4\u30c9\u521d\u671f\u6295\u4e0e\u91cf\u3001PEXIVAS\u306f\u6f38\u6e1b\u901f\u5ea6\u3092\u691c\u8a3c\u3057\u305f\u3002\" class=\"wp-image-10016\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-53-480x600.png 480w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-53-240x300.png 240w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-53-767x959.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-53.png 800w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1aANCA\u95a2\u9023\u8840\u7ba1\u708e\u306b\u304a\u3051\u308b\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u6226\u7565\u3092\u691c\u8a3c\u3057\u305fLoVAS\u8a66\u9a13\u3068PEXIVAS\u8a66\u9a13\u306e\u6bd4\u8f03\u3002LoVAS\u8a66\u9a13\u306f\u91cd\u75c7\u814e\u969c\u5bb3\u30fb\u91cd\u75c7\u80ba\u80de\u51fa\u8840\u3092\u9664\u5916\u3057\u305f\u65b0\u898f\u8a3a\u65adAAV\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u4f75\u7528\u4e0b\u3067\u30b9\u30c6\u30ed\u30a4\u30c9\u521d\u671f\u6295\u4e0e\u91cf\u3092\u6bd4\u8f03\u3057\u305f\u3002\u4e00\u65b9\u3001PEXIVAS\u8a66\u9a13\u3067\u306f\u3001\u91cd\u75c7AAV\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u521d\u671f\u6cbb\u7642\u5f8c\u306e\u30b9\u30c6\u30ed\u30a4\u30c9\u6f38\u6e1b\u901f\u5ea6\u3092\u6bd4\u8f03\u3057\u305f\u3002\u4e21\u8a66\u9a13\u306f\u5bfe\u8c61\u60a3\u8005\u3068\u6cbb\u7642\u8a2d\u8a08\u304c\u7570\u306a\u308b\u305f\u3081\u3001\u7d50\u679c\u3092\u76f4\u63a5\u6bd4\u8f03\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u306a\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c6\u7ae0\uff0eLoVAS\u8a66\u9a13\u306e\u9650\u754c<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u306e\u7d50\u679c\u3092\u5b9f\u81e8\u5e8a\u3078\u9069\u7528\u3059\u308b\u969b\u306b\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u9650\u754c\u306b\u6ce8\u610f\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u91cd\u75c7\u814e\u708e\u30fb\u91cd\u75c7\u80ba\u80de\u51fa\u8840\u3078\u306e\u4e00\u822c\u5316\u306f\u56f0\u96e3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u3067\u306f\u3001eGFR 15 mL\/min\/1.73 m\u00b2\u672a\u6e80\u306e\u91cd\u75c7\u7cf8\u7403\u4f53\u814e\u708e\u3084\u3001\u9ad8\u6d41\u91cf\u306e\u9178\u7d20\u6295\u4e0e\u3092\u5fc5\u8981\u3068\u3059\u308b\u80ba\u80de\u51fa\u8840\u306a\u3069\u304c\u9664\u5916\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u6025\u901f\u306b\u814e\u6a5f\u80fd\u304c\u60aa\u5316\u3057\u3066\u3044\u308b\u60a3\u8005\u3084\u91cd\u75c7\u80ba\u80de\u51fa\u8840\u3092\u4f34\u3046\u60a3\u8005\u306b\u3001\u305d\u306e\u307e\u307e\u9069\u7528\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 MPO-ANCA\u967d\u6027\u60a3\u8005\u304c\u591a\u304b\u3063\u305f<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a66\u9a13\u53c2\u52a0\u8005\u306e\u7d0486\uff05\u304cMPO-ANCA\u967d\u6027\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65e5\u672c\u306eMPA\u60a3\u8005\u306b\u95a2\u9023\u6027\u306e\u9ad8\u3044\u7814\u7a76\u3067\u3042\u308b\u4e00\u65b9\u3001PR3-ANCA\u967d\u6027GPA\u306a\u3069\u3001\u518d\u71c3\u30ea\u30b9\u30af\u3084\u75c5\u578b\u306e\u7570\u306a\u308b\u60a3\u8005\u3078\u306e\u4e00\u822c\u5316\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u975e\u76f2\u691c\u8a66\u9a13\u3067\u3042\u3063\u305f<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u60a3\u8005\u3068\u62c5\u5f53\u533b\u306f\u6cbb\u7642\u7fa4\u3092\u8a8d\u8b58\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u75be\u60a3\u6d3b\u52d5\u6027\u306b\u306f\u6a19\u6e96\u5316\u3055\u308c\u305f\u8a55\u4fa1\u65b9\u6cd5\u304c\u7528\u3044\u3089\u308c\u307e\u3057\u305f\u304c\u3001\u975e\u76f2\u691c\u306b\u3088\u308b\u5224\u65ad\u3078\u306e\u5f71\u97ff\u3092\u5b8c\u5168\u306b\u306f\u9664\u5916\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u975e\u52a3\u6027\u30de\u30fc\u30b8\u30f3\u304c\u6bd4\u8f03\u7684\u5927\u304d\u304b\u3063\u305f<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a2d\u5b9a\u3055\u308c\u305f\u975e\u52a3\u6027\u30de\u30fc\u30b8\u30f3\u306f\u221220\u30d1\u30fc\u30bb\u30f3\u30c8\u30dd\u30a4\u30f3\u30c8\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u975e\u52a3\u6027\u306e\u7d71\u8a08\u5b66\u7684\u57fa\u6e96\u3092\u6e80\u305f\u3057\u3066\u3044\u3066\u3082\u3001\u81e8\u5e8a\u7684\u306b\u3069\u3053\u307e\u3067\u306e\u52b9\u679c\u4f4e\u4e0b\u3092\u8a31\u5bb9\u3067\u304d\u308b\u304b\u306f\u60a3\u8005\u306e\u72b6\u614b\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2464 \u9577\u671f\u4e88\u5f8c\u3092\u8a55\u4fa1\u3059\u308b\u306b\u306f\u75c7\u4f8b\u6570\u304c\u9650\u3089\u308c\u3066\u3044\u305f<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u767b\u9332\u60a3\u8005\u306f140\u4eba\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b7b\u4ea1\u3001\u672b\u671f\u814e\u4e0d\u5168\u3001\u4e3b\u8981\u518d\u71c3\u306a\u3069\u306b\u3064\u3044\u3066\u3001\u7fa4\u9593\u5dee\u304c\u306a\u3044\u3053\u3068\u3092\u78ba\u5b9f\u306b\u8a3c\u660e\u3067\u304d\u308b\u898f\u6a21\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c7\u7ae0\uff0eADVOCATE\u8a66\u9a13\u306e\u64a4\u56de\u3068\u73fe\u5728\u306eAAV\u6cbb\u7642<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">ANCA\u95a2\u9023\u8840\u7ba1\u708e\u306b\u304a\u3051\u308b\u30b9\u30c6\u30ed\u30a4\u30c9\u66dd\u9732\u91cf\u306e\u4f4e\u6e1b\u3092\u76ee\u6307\u3057\u305f\u7814\u7a76\u3068\u3057\u3066\u3001LoVAS\u8a66\u9a13\u3084PEXIVAS\u8a66\u9a13\u306e\u307b\u304b\u306bADVOCATE\u8a66\u9a13\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ADVOCATE\u8a66\u9a13\u306f\u3001C5a\u53d7\u5bb9\u4f53\u963b\u5bb3\u85ac\u30a2\u30d0\u30b3\u30d1\u30f3\u306e\u6709\u52b9\u6027\u3092\u691c\u8a3c\u3057\u305f\u7b2cIII\u76f8\u81e8\u5e8a\u8a66\u9a13\u3067\u30012021\u5e74\u306bNew England Journal of Medicine\u8a8c\u306b\u767a\u8868\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001<strong>\u3053\u306e\u8ad6\u6587\u306f2026\u5e746\u670829\u65e5\u306b\u6b63\u5f0f\u306b\u64a4\u56de\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">ADVOCATE\u8a66\u9a13\u304c\u64a4\u56de\u3055\u308c\u305f\u7406\u7531<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u7c73\u56fdFDA\u306e\u8abf\u67fb\u3067\u3001\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u56fa\u5b9a\u304a\u3088\u3073\u76f2\u691c\u89e3\u9664\u5f8c\u306b\u30019\u4eba\u306e\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306e\u5224\u5b9a\u304c\u518d\u8a55\u4fa1\u3055\u308c\u3066\u3044\u305f\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u624b\u7d9a\u304d\u306f\u539f\u8457\u8ad6\u6587\u3067\u958b\u793a\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u7814\u7a76\u30c7\u30fc\u30bf\u306e\u4fe1\u983c\u6027\u306b\u91cd\u5927\u306a\u554f\u984c\u304c\u3042\u308b\u3068\u5224\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NEJM\u7de8\u96c6\u90e8\u306f\u30012026\u5e746\u670829\u65e5\u306b\u6b63\u5f0f\u306a\u64a4\u56de\u901a\u77e5\u3092\u516c\u8868\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6d77\u5916\u898f\u5236\u5f53\u5c40\u306e\u5bfe\u5fdc<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b27\u5dde\u3067\u306f\u3001ADVOCATE\u8a66\u9a13\u306e\u30c7\u30fc\u30bf\u3092\u6709\u52b9\u6027\u306e\u78ba\u5b9f\u306a\u6839\u62e0\u3068\u3057\u3066\u4f7f\u7528\u3067\u304d\u306a\u3044\u3068\u5224\u65ad\u3055\u308c\u30012026\u5e748\u6708\u306b\u30a2\u30d0\u30b3\u30d1\u30f3\u306e\u8ca9\u58f2\u627f\u8a8d\u304c\u53d6\u308a\u6d88\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u91cd\u7be4\u306a\u809d\u969c\u5bb3\u306a\u3069\u306e\u5b89\u5168\u6027\u4e0a\u306e\u61f8\u5ff5\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u65e5\u672c\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068\u5b89\u5168\u6027\u5bfe\u5fdc<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u65e5\u672c\u3067\u306f\u3001ADVOCATE\u8a66\u9a13\u306e\u8ad6\u6587\u64a4\u56de\u3092\u53d7\u3051\u30012026\u5e747\u67082\u65e5\u306b\u300cANCA\u95a2\u9023\u8840\u7ba1\u708e\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32023\u300d\u306b\u304a\u3051\u308b\u30a2\u30d0\u30b3\u30d1\u30f3\u306e\u63a8\u5968\u3092\u524a\u9664\u3059\u308b\u65b9\u91dd\u304c\u516c\u8868\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u30012026\u5e7410\u670821\u65e5\u306b\u306f\u539a\u751f\u52b4\u50cd\u7701\u304b\u3089\u30a2\u30d0\u30b3\u30d1\u30f3\u88fd\u5264\u306e\u4f7f\u7528\u306b\u95a2\u3059\u308b\u7559\u610f\u4e8b\u9805\u304c\u767a\u51fa\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2026\u5e7411\u67084\u65e5\u306b\u306f\u3001\u65e5\u672c\u30ea\u30a6\u30de\u30c1\u5b66\u4f1a\u30fb\u65e5\u672c\u814e\u81d3\u5b66\u4f1a\u5408\u540c\u30bf\u30d6\u30cd\u30aa\u30b9\u5b89\u5168\u6027\u691c\u8a0e\u30bf\u30b9\u30af\u30d5\u30a9\u30fc\u30b9\u306b\u3088\u308b\u3001\u6cbb\u7642\u4e2d\u6b62\u6642\u306e\u5bfe\u5fdc\u3068\u60a3\u8005\u5411\u3051\u8aac\u660e\u8cc7\u6599\u304c\u516c\u8868\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30a2\u30d0\u30b3\u30d1\u30f3\u306e\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u60a3\u8005\u306b\u3064\u3044\u3066\u306f\u3001\u81ea\u5df1\u5224\u65ad\u306b\u3088\u308b\u4e2d\u6b62\u3067\u306f\u306a\u304f\u3001\u62c5\u5f53\u533b\u306e\u7ba1\u7406\u4e0b\u3067\u75be\u60a3\u6d3b\u52d5\u6027\u3068\u4ee3\u66ff\u6cbb\u7642\u3092\u8a55\u4fa1\u3057\u3001\u8a08\u753b\u7684\u306b\u5bfe\u5fdc\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 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class=\"wp-block-list\">\n<li>\u8840\u5c3f\u30fb\u86cb\u767d\u5c3f\u306a\u3069\u306e\u5c3f\u6240\u898b<\/li>\n\n\n\n<li>\u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u3001eGFR<\/li>\n\n\n\n<li>\u547c\u5438\u5668\u75c7\u72b6\u3084\u753b\u50cf\u6240\u898b<\/li>\n\n\n\n<li>\u672b\u68a2\u795e\u7d4c\u969c\u5bb3<\/li>\n\n\n\n<li>CRP\u306a\u3069\u306e\u708e\u75c7\u53cd\u5fdc<\/li>\n\n\n\n<li>\u611f\u67d3\u75c7\u306e\u5fb4\u5019<\/li>\n\n\n\n<li>\u30b9\u30c6\u30ed\u30a4\u30c9\u304a\u3088\u3073\u514d\u75ab\u6291\u5236\u7642\u6cd5\u306b\u3088\u308b\u6709\u5bb3\u4e8b\u8c61<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">ANCA\u6297\u4f53\u4fa1\u3060\u3051\u3067\u518d\u71c3\u3092\u5224\u65ad\u3059\u308b\u3053\u3068\u306f\u9069\u5207\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u81e8\u5e8a\u75c7\u72b6\u3001\u81d3\u5668\u969c\u5bb3\u3001\u5c3f\u6240\u898b\u3001\u753b\u50cf\u6240\u898b\u306a\u3069\u3092\u7dcf\u5408\u7684\u306b\u8a55\u4fa1\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u60a3\u8005\u3055\u3093\u3078\u306e\u8aac\u660e<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u300c\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u6e1b\u3089\u3059\u3068\u75c5\u6c17\u304c\u518d\u71c3\u3059\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u300d\u3068\u4e0d\u5b89\u306b\u611f\u3058\u308b\u60a3\u8005\u3055\u3093\u306f\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u306f\u3001\u9069\u5207\u306a\u514d\u75ab\u6291\u5236\u7642\u6cd5\u3092\u4f75\u7528\u3057\u305f\u5834\u5408\u3001\u5bfe\u8c61\u3068\u306a\u3063\u305f\u60a3\u8005\u96c6\u56e3\u3067\u306f\u3001\u5f93\u6765\u3088\u308a\u5c11\u306a\u3044\u30b9\u30c6\u30ed\u30a4\u30c9\u91cf\u3067\u3082\u5341\u5206\u306a\u5bdb\u89e3\u5c0e\u5165\u304c\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u5b89\u5168\u306b\u6e1b\u3089\u305b\u308b\u304b\u3069\u3046\u304b\u306f\u3001\u75c5\u578b\u3084\u81d3\u5668\u969c\u5bb3\u3001\u518d\u71c3\u30ea\u30b9\u30af\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u81ea\u5df1\u5224\u65ad\u3067\u85ac\u3092\u6e1b\u91cf\u30fb\u4e2d\u6b62\u305b\u305a\u3001\u62c5\u5f53\u533b\u306b\u3088\u308b\u5b9a\u671f\u7684\u306a\u8a55\u4fa1\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u307e\u3068\u3081<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u306f\u3001\u65e5\u672c\u304b\u3089\u767a\u4fe1\u3055\u308c\u305fANCA\u95a2\u9023\u8840\u7ba1\u708e\u306b\u304a\u3051\u308b\u91cd\u8981\u306a\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u4f75\u7528\u4e0b\u3067\u306f\u3001\u521d\u671fPSL\u6295\u4e0e\u91cf\u30920.5 mg\/kg\/\u65e5\u306b\u6e1b\u91cf\u3057\u3066\u3082\u30016\u304b\u6708\u5bdb\u89e3\u5c0e\u5165\u7387\u306b\u3064\u3044\u3066\u6a19\u6e96\u91cf\u7642\u6cd5\u306b\u5bfe\u3059\u308b\u975e\u52a3\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7fa4\u3067\u306f\u91cd\u7be4\u306a\u611f\u67d3\u75c7\u3084\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u304c\u6709\u610f\u306b\u5c11\u306a\u3044\u7d50\u679c\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2\u5e74\u9593\u306e\u8ffd\u8de1\u7814\u7a76\u3067\u3082\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u4e2d\u6b62\u5272\u5408\u306e\u5897\u52a0\u3068\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u306e\u6e1b\u5c11\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u91cd\u75c7\u814e\u969c\u5bb3\u3084\u91cd\u75c7\u80ba\u80de\u51fa\u8840\u3092\u4f34\u3046\u60a3\u8005\u306f\u9664\u5916\u3055\u308c\u3066\u3044\u305f\u3053\u3068\u3001<strong>\u9577\u671f\u518d\u71c3\u30ea\u30b9\u30af\u306e\u540c\u7b49\u6027\u304c\u8a3c\u660e\u3055\u308c\u305f\u308f\u3051\u3067\u306f\u306a\u3044<\/strong>\u3053\u3068\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001C5a\u53d7\u5bb9\u4f53\u963b\u5bb3\u85ac\u30a2\u30d0\u30b3\u30d1\u30f3\u306e\u6709\u52b9\u6027\u3092\u691c\u8a3c\u3057\u305fADVOCATE\u8a66\u9a13\u306f2026\u5e74\u306b\u6b63\u5f0f\u64a4\u56de\u3055\u308c\u3001\u56fd\u5185\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u63a8\u5968\u304b\u3089\u3082\u524a\u9664\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u3068PEXIVAS\u8a66\u9a13\u306f\u3001\u3053\u3046\u3057\u305f\u5909\u5316\u3092\u8e0f\u307e\u3048\u305f\u73fe\u5728\u306eANCA\u95a2\u9023\u8840\u7ba1\u708e\u8a3a\u7642\u306b\u304a\u3044\u3066\u3082\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u66dd\u9732\u91cf\u3092\u6e1b\u3089\u3059\u6cbb\u7642\u6226\u7565\u3092\u8003\u3048\u308b\u3046\u3048\u3067\u91cd\u8981\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>ANCA\u95a2\u9023\u8840\u7ba1\u708e\u306e\u6cbb\u7642\u3067\u306f\u3001\u75be\u60a3\u6d3b\u52d5\u6027\u3092\u5341\u5206\u306b\u6291\u5236\u3057\u306a\u304c\u3089\u3001\u611f\u67d3\u75c7\u3084\u85ac\u5264\u6709\u5bb3\u4e8b\u8c61\u3092\u6700\u5c0f\u9650\u306b\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u5f53\u9662\u3067\u306e\u30ea\u30a6\u30de\u30c1\u30fb\u81a0\u539f\u75c5\u8a3a\u7642\u306b\u3064\u3044\u3066<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u3001\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u30fb\u30ea\u30a6\u30de\u30c1\u5c02\u9580\u533b\u306b\u3088\u308b\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3001\u81a0\u539f\u75c5\u3001\u8840\u7ba1\u708e\u75c7\u5019\u7fa4\u306a\u3069\u306e\u8a3a\u7642\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ANCA\u95a2\u9023\u8840\u7ba1\u708e\u3067\u306f\u3001\u814e\u81d3\u3001\u80ba\u3001\u672b\u68a2\u795e\u7d4c\u306a\u3069\u8907\u6570\u306e\u81d3\u5668\u306b\u75c7\u72b6\u304c\u73fe\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u5168\u8eab\u72b6\u614b\u3092\u7dcf\u5408\u7684\u306b\u8a55\u4fa1\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u6db2\u691c\u67fb\u3001\u5c3f\u691c\u67fb\u3001\u753b\u50cf\u691c\u67fb\u306a\u3069\u3092\u7d44\u307f\u5408\u308f\u305b\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u9ad8\u5ea6\u533b\u7642\u6a5f\u95a2\u3068\u9023\u643a\u3057\u3066\u8a3a\u7642\u3092\u884c\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u539f\u56e0\u4e0d\u660e\u306e\u708e\u75c7\u53cd\u5fdc\u4e0a\u6607\u3001\u8840\u5c3f\u30fb\u86cb\u767d\u5c3f\u3001\u606f\u5207\u308c\u3001\u9577\u5f15\u304f\u767a\u71b1\u3001\u624b\u8db3\u306e\u3057\u3073\u308c\u306a\u3069\u3067\u304a\u56f0\u308a\u306e\u65b9\u306f\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/rheumatology-allergy.html\" target=\"_blank\" rel=\"noopener\">\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af\uff5c\u30ea\u30a6\u30de\u30c1\u30fb\u81a0\u539f\u75c5\u30fb\u30a2\u30ec\u30eb\u30ae\u30fc\u5185\u79d1<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u95a2\u9023\u8a18\u4e8b<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1\uff0ePEXIVAS\u8a66\u9a13\uff5cANCA\u95a2\u9023\u8840\u7ba1\u708e\u306b\u304a\u3051\u308b\u8840\u6f3f\u4ea4\u63db\u3068\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u7642\u6cd5<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">LoVAS\u8a66\u9a13\u304c\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u4f75\u7528\u4e0b\u3067\u306e\u30b9\u30c6\u30ed\u30a4\u30c9\u521d\u671f\u6295\u4e0e\u91cf\u306e\u6e1b\u91cf\u3092\u691c\u8a3c\u3057\u305f\u306e\u306b\u5bfe\u3057\u3001PEXIVAS\u8a66\u9a13\u3067\u306f\u3001\u91cd\u75c7ANCA\u95a2\u9023\u8840\u7ba1\u708e\u306b\u304a\u3051\u308b\u8840\u6f3f\u4ea4\u63db\u306e\u6709\u52b9\u6027\u3068\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u6025\u901f\u6f38\u6e1b\u304c\u691c\u8a0e\u3055\u308c\u307e\u3057\u305f\u3002\u4e21\u8a66\u9a13\u3092\u6bd4\u8f03\u3059\u308b\u3053\u3068\u3067\u3001\u75c5\u72b6\u306e\u91cd\u75c7\u5ea6\u306b\u5fdc\u3058\u305f\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf\u6226\u7565\u3078\u306e\u7406\u89e3\u304c\u6df1\u307e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/pexivas-trial-anca-vasculitis-plasma-exchange-glucocorticoids\/\" target=\"_blank\" rel=\"noopener\">PEXIVAS\u8a66\u9a13\u306e\u8a73\u3057\u3044\u89e3\u8aac\u306f\u3053\u3061\u3089<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2\uff0e\u773c\u75c7\u72b6\u304c\u5f37\u304f\u51fa\u305f\u591a\u767a\u8840\u7ba1\u708e\u6027\u8089\u82bd\u816b\u75c7\uff08GPA\uff09\u306e\u4e00\u4f8b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">ANCA\u95a2\u9023\u8840\u7ba1\u708e\u306f\u814e\u81d3\u3084\u80ba\u3060\u3051\u3067\u306a\u304f\u3001\u773c\u3084\u8033\u9f3b\u54bd\u5589\u9818\u57df\u306a\u3069\u306b\u3082\u591a\u5f69\u306a\u75c7\u72b6\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u672c\u75c7\u4f8b\u3067\u306f\u3001\u773c\u75c7\u72b6\u3092\u5951\u6a5f\u3068\u3057\u3066GPA\u306e\u8a3a\u65ad\u306b\u81f3\u3063\u305f\u81e8\u5e8a\u7d4c\u904e\u3092\u7d39\u4ecb\u3057\u3066\u3044\u307e\u3059\u3002LoVAS\u8a66\u9a13\u3067\u6271\u308f\u308c\u305f\u75be\u60a3\u306e\u5b9f\u969b\u306e\u81e8\u5e8a\u50cf\u3092\u7406\u89e3\u3059\u308b\u3046\u3048\u3067\u53c2\u8003\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-2522\/\" target=\"_blank\" rel=\"noopener\">\u773c\u75c7\u72b6\u304c\u5f37\u304f\u51fa\u305fGPA\u75c7\u4f8b\u306f\u3053\u3061\u3089<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">3\uff0e\u81a0\u539f\u75c5\u30fb\u8840\u7ba1\u708e\u306e\u6b7b\u4ea1\u7387\u3068\u6b7b\u56e0\uff5c\u82f1\u56fd\u5168\u56fd\u7814\u7a762026<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">ANCA\u95a2\u9023\u8840\u7ba1\u708e\u306e\u6cbb\u7642\u3067\u306f\u3001\u539f\u75be\u60a3\u306e\u5236\u5fa1\u306b\u52a0\u3048\u3001\u611f\u67d3\u75c7\u3084\u81d3\u5668\u969c\u5bb3\u306a\u3069\u306e\u9577\u671f\u7684\u306a\u30ea\u30b9\u30af\u3078\u306e\u5bfe\u5fdc\u304c\u91cd\u8981\u3067\u3059\u3002\u82f1\u56fd\u306e\u5168\u56fd\u898f\u6a21\u306e\u7814\u7a76\u304b\u3089\u3001\u5e0c\u5c11\u81ea\u5df1\u514d\u75ab\u6027\u30ea\u30a6\u30de\u30c1\u75be\u60a3\u306e\u6b7b\u4ea1\u7387\u3068\u6b7b\u56e0\u3092\u89e3\u8aac\u3057\u3001\u6cbb\u7642\u306e\u6709\u52b9\u6027\u3060\u3051\u3067\u306a\u304f\u5b89\u5168\u6027\u3092\u91cd\u8996\u3059\u308b\u610f\u7fa9\u3092\u8003\u5bdf\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/rare-autoimmune-rheumatic-diseases-mortality-england-2026\/\" target=\"_blank\" rel=\"noopener\">\u81a0\u539f\u75c5\u30fb\u8840\u7ba1\u708e\u306e\u6b7b\u4ea1\u7387\u3068\u6b7b\u56e0\u306e\u89e3\u8aac\u306f\u3053\u3061\u3089<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<ol start=\"1\" class=\"wp-block-list\">\n<li>Furuta S, et al. Effect of Reduced-Dose vs High-Dose Glucocorticoids Added to Rituximab on Remission Induction in ANCA-Associated Vasculitis: A Randomized Clinical Trial. JAMA. 2021;325:2178\u20132187. DOI: 10.1001\/jama.2021.6615.<\/li>\n\n\n\n<li>Furuta S, et al. Reduced-dose versus high-dose glucocorticoids added to rituximab on remission induction in ANCA-associated vasculitis: predefined 2-year follow-up study. Ann Rheum Dis. 2024;83:96\u2013102.<\/li>\n\n\n\n<li>Walsh M, et al. Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis. N Engl J Med. 2020;382:622\u2013631. DOI: 10.1056\/NEJMoa1803537.<\/li>\n\n\n\n<li>Hellmich B, et al. EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update. Ann Rheum Dis. 2024;83:30\u201347.<\/li>\n\n\n\n<li>KDIGO ANCA Vasculitis Work Group. KDIGO 2024 Clinical Practice Guideline for the Management of Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis. Kidney Int. 2024.<\/li>\n\n\n\n<li>Rubin EJ. Retraction: Jayne DRW et al. Avacopan for the Treatment of ANCA-Associated Vasculitis. N Engl J Med. 2026. DOI: 10.1056\/NEJMe2608684.<\/li>\n\n\n\n<li>\u539a\u751f\u52b4\u50cd\u7701\uff0e\u30bf\u30d6\u30cd\u30aa\u30b9\u30ab\u30d7\u30bb\u30eb10 mg\u306b\u4fc2\u308b\u5bfe\u5fdc\u306b\u3064\u3044\u3066\uff0e2026\u5e7410\u670821\u65e5\uff0e<\/li>\n\n\n\n<li>\u65e5\u672c\u30ea\u30a6\u30de\u30c1\u5b66\u4f1a\u30fb\u65e5\u672c\u814e\u81d3\u5b66\u4f1a\u5408\u540c\u30bf\u30d6\u30cd\u30aa\u30b9\u5b89\u5168\u6027\u691c\u8a0e\u30bf\u30b9\u30af\u30d5\u30a9\u30fc\u30b9\uff0e\u30bf\u30d6\u30cd\u30aa\u30b9\uff08\u30a2\u30d0\u30b3\u30d1\u30f3\uff09\u306e\u4e2d\u6b62\u3068\u305d\u306e\u5f8c\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066\uff0e2026\u5e7411\u67084\u65e5\uff0e<\/li>\n<\/ol>\n<\/blockquote>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow 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