{"id":10046,"date":"2026-11-12T14:47:01","date_gmt":"2026-11-12T05:47:01","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=10046"},"modified":"2026-11-12T14:54:21","modified_gmt":"2026-11-12T05:54:21","slug":"blog-anifrolumab-belimumab-cardiovascular-risk-sle-2026","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/blog-anifrolumab-belimumab-cardiovascular-risk-sle-2026\/","title":{"rendered":"SLE\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\uff5c\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u3068\u30d9\u30ea\u30e0\u30de\u30d6\u3092\u6bd4\u8f03\u3057\u305f2026\u5e74\u7814\u7a76"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\u306f\u3001\u514d\u75ab\u306e\u7570\u5e38\u306b\u3088\u3063\u3066\u76ae\u819a\u3001\u95a2\u7bc0\u3001\u814e\u81d3\u3001\u8840\u6db2\u306a\u3069\u5168\u8eab\u306e\u81d3\u5668\u306b\u708e\u75c7\u3092\u751f\u3058\u308b\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u306e\u6cbb\u7642\u3067\u306f\u3001\u75be\u60a3\u6d3b\u52d5\u6027\u3092\u6291\u3048\u3066\u81d3\u5668\u969c\u5bb3\u3092\u9632\u3050\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u304c\u3001\u8fd1\u5e74\u306f\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\u3001\u5fc3\u4e0d\u5168\u306a\u3069\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u3092\u4e88\u9632\u3059\u308b\u3053\u3068\u3082\u5927\u304d\u306a\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u60a3\u8005\u3055\u3093\u3067\u306f\u3001\u4e00\u822c\u4eba\u53e3\u3068\u6bd4\u8f03\u3057\u3066\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u80cc\u666f\u306b\u306f\u3001\u9ad8\u8840\u5727\u3084\u8102\u8cea\u7570\u5e38\u75c7\u306a\u3069\u306e\u5f93\u6765\u306e\u5371\u967a\u56e0\u5b50\u306b\u52a0\u3048\u3066\u3001\u6162\u6027\u7684\u306a\u708e\u75c7\u3001\u8840\u7ba1\u5185\u76ae\u969c\u5bb3\u3001\u514d\u75ab\u7570\u5e38\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u6cbb\u7642\u306a\u3069\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2026\u5e74\u3001\u7c73\u56fd\u30ea\u30a6\u30de\u30c1\u5b66\u4f1a\u306e\u5b66\u8853\u8a8c\u300eArthritis &amp; Rheumatology\u300f\u306b\u3001SLE\u6cbb\u7642\u85ac\u3067\u3042\u308b\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u3068\u30d9\u30ea\u30e0\u30de\u30d6\u306e\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u767a\u751f\u30ea\u30b9\u30af\u3092\u6bd4\u8f03\u3057\u305f\u7814\u7a76\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u3092\u958b\u59cb\u3057\u305f\u60a3\u8005\u7fa4\u3067\u3001\u30d9\u30ea\u30e0\u30de\u30d6\u3092\u958b\u59cb\u3057\u305f\u60a3\u8005\u7fa4\u3088\u308a\u3082\u5fc3\u4e0d\u5168\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\u306a\u3069\u306e\u767a\u751f\u30ea\u30b9\u30af\u304c\u4f4e\u3044\u3068\u3044\u3046\u7d50\u679c\u304c\u5f97\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u89b3\u5bdf\u7814\u7a76\u3067\u3042\u308a\u3001\u85ac\u5264\u81ea\u4f53\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u4fdd\u8b77\u4f5c\u7528\u304c\u8a3c\u660e\u3055\u308c\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306f\u3001\u3053\u306e\u7814\u7a76\u306e\u7d50\u679c\u3068\u81e8\u5e8a\u7684\u306a\u610f\u7fa9\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c1\u7ae0\uff0eSLE\u60a3\u8005\u3067\u306f\u306a\u305c\u5fc3\u8840\u7ba1\u75be\u60a3\u304c\u554f\u984c\u306b\u306a\u308b\u306e\u304b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u306e\u57fa\u672c\u7684\u306a\u75c5\u614b\u3001\u8a3a\u65ad\u3001\u6cbb\u7642\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-1987\/\" target=\"_blank\" rel=\"noopener\">\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\uff1a\u81e8\u5e8a\u30a2\u30c3\u30d7\u30c7\u30fc\u30c8<\/a>\u3067\u8a73\u3057\u304f\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 SLE\u3067\u306f\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u3067\u306f\u3001\u75be\u60a3\u305d\u306e\u3082\u306e\u306b\u4f34\u3046\u6162\u6027\u708e\u75c7\u3084\u514d\u75ab\u7570\u5e38\u304c\u52d5\u8108\u786c\u5316\u3084\u8840\u7ba1\u969c\u5bb3\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u91cd\u8981\u306a\u8981\u56e0\u3068\u3057\u3066\u3001\u4ee5\u4e0b\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6162\u6027\u7684\u306a\u5168\u8eab\u6027\u708e\u75c7<\/li>\n\n\n\n<li>\u8840\u7ba1\u5185\u76ae\u6a5f\u80fd\u969c\u5bb3<\/li>\n\n\n\n<li>I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u7d4c\u8def\u306e\u6d3b\u6027\u5316<\/li>\n\n\n\n<li>\u597d\u4e2d\u7403\u7d30\u80de\u5916\u30c8\u30e9\u30c3\u30d7\uff08NETs\uff09\u306b\u3088\u308b\u8840\u7ba1\u50b7\u5bb3<\/li>\n\n\n\n<li>\u9ad8\u8840\u5727\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u7cd6\u5c3f\u75c5<\/li>\n\n\n\n<li>\u814e\u969c\u5bb3\u3084\u30b9\u30c6\u30ed\u30a4\u30c9\u3078\u306e\u7d2f\u7a4d\u66dd\u9732<\/li>\n\n\n\n<li>\u6297\u30ea\u30f3\u8102\u8cea\u6297\u4f53\u306b\u95a2\u9023\u3059\u308b\u8840\u6813\u75c7<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u304c\u8907\u5408\u7684\u306b\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067\u3001SLE\u60a3\u8005\u3067\u306f\u82e5\u5e74\u3067\u3042\u3063\u3066\u3082\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u3068\u8840\u7ba1\u969c\u5bb3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u306e\u75c5\u614b\u5f62\u6210\u306b\u306f\u3001I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u3001\u7279\u306bIFN-\u03b1\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u7d4c\u8def\u306e\u6301\u7d9a\u7684\u306a\u6d3b\u6027\u5316\u306f\u3001\u81ea\u5df1\u514d\u75ab\u53cd\u5fdc\u3092\u5897\u5e45\u3055\u305b\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u8840\u7ba1\u5185\u76ae\u306e\u6052\u5e38\u6027\u3092\u969c\u5bb3\u3057\u3001\u8840\u7ba1\u4fee\u5fa9\u80fd\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001NETs\u5f62\u6210\u3084\u708e\u75c7\u7d30\u80de\u306e\u6d3b\u6027\u5316\u3092\u4ecb\u3057\u3066\u3001\u52d5\u8108\u786c\u5316\u6027\u75c5\u5909\u306e\u5f62\u6210\u3084\u8840\u7ba1\u50b7\u5bb3\u306b\u95a2\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u305f\u3081\u3001I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u7d4c\u8def\u3092\u963b\u5bb3\u3059\u308b\u6cbb\u7642\u304c\u3001SLE\u306e\u75be\u60a3\u6d3b\u52d5\u6027\u3060\u3051\u3067\u306a\u304f\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306b\u3082\u5f71\u97ff\u3059\u308b\u53ef\u80fd\u6027\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c2\u7ae0\uff0e\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u3068\u30d9\u30ea\u30e0\u30de\u30d6\u306e\u4f5c\u7528\u6a5f\u5e8f<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\uff08\u30b5\u30d5\u30cd\u30ed\u30fc\uff09<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u306f\u3001I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u53d7\u5bb9\u4f53\u306e\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u3067\u3042\u308bIFNAR1\u306b\u7d50\u5408\u3059\u308b\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u53d7\u5bb9\u4f53\u3092\u4ecb\u3057\u305f\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u963b\u5bb3\u3057\u3001\u4e0b\u6d41\u306eJAK-STAT\u7d4c\u8def\u3084\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u523a\u6fc0\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u6291\u5236\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306b\u3088\u308a\u3001SLE\u306b\u7279\u5fb4\u7684\u306a\u514d\u75ab\u6d3b\u6027\u5316\u3084\u708e\u75c7\u53cd\u5fdc\u3092\u6291\u5236\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u76ae\u819a\u75c7\u72b6\u3084\u95a2\u7bc0\u75c7\u72b6\u306a\u3069\u3092\u6709\u3059\u308bSLE\u60a3\u8005\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u9078\u629e\u80a2\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u30d9\u30ea\u30e0\u30de\u30d6\uff08\u30d9\u30f3\u30ea\u30b9\u30bf\uff09<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d9\u30ea\u30e0\u30de\u30d6\u306f\u3001\u53ef\u6eb6\u6027B\u7d30\u80de\u6d3b\u6027\u5316\u56e0\u5b50BAFF\uff08BLyS\uff09\u3092\u6a19\u7684\u3068\u3059\u308b\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BAFF\u306fB\u7d30\u80de\u306e\u751f\u5b58\u3084\u5206\u5316\u3092\u652f\u3048\u308b\u91cd\u8981\u306a\u56e0\u5b50\u3067\u3042\u308a\u3001SLE\u3067\u306f\u305d\u306e\u6d3b\u6027\u5316\u304c\u81ea\u5df1\u6297\u4f53\u7523\u751f\u3084\u514d\u75ab\u7570\u5e38\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u4e21\u85ac\u5264\u3068\u3082SLE\u306b\u5bfe\u3057\u3066\u6709\u52b9\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4f5c\u7528\u3059\u308b\u514d\u75ab\u7d4c\u8def\u306f\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7814\u7a76\u306f\u3001\u3053\u306e\u4f5c\u7528\u6a5f\u5e8f\u306e\u9055\u3044\u304c\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u767a\u751f\u30ea\u30b9\u30af\u306b\u3082\u95a2\u4fc2\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304b\u3092\u691c\u8a0e\u3057\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"565\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-66-565x600.png\" alt=\"SLE\u6cbb\u7642\u85ac\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u306eIFNAR1\u963b\u5bb3\u3068\u30d9\u30ea\u30e0\u30de\u30d6\u306eBAFF\u963b\u5bb3\u3092\u6bd4\u8f03\u3057\u305f\u4f5c\u7528\u6a5f\u5e8f\u56f3\u3002\" class=\"wp-image-10047\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-66-565x600.png 565w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-66-283x300.png 283w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-66-768x815.png 768w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-66.png 800w\" sizes=\"auto, (max-width: 565px) 100vw, 565px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1a\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u306fI\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u53d7\u5bb9\u4f53IFNAR1\u3092\u963b\u5bb3\u3057\u3001\u4e0b\u6d41\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u6291\u5236\u3059\u308b\u3002\u4e00\u65b9\u3001\u30d9\u30ea\u30e0\u30de\u30d6\u306f\u53ef\u6eb6\u6027BAFF\u3092\u963b\u5bb3\u3057\u3001B\u7d30\u80de\u306e\u751f\u5b58\u30b7\u30b0\u30ca\u30eb\u3092\u6291\u5236\u3059\u308b\u3002I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u7d4c\u8def\u306e\u6291\u5236\u304c\u8840\u7ba1\u708e\u75c7\u3084\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304c\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u6291\u5236\u3078\u306e\u76f4\u63a5\u7684\u306a\u56e0\u679c\u95a2\u4fc2\u306f\u78ba\u7acb\u3057\u3066\u3044\u306a\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c3\u7ae0\uff0e2026\u5e74\u7814\u7a76\u306e\u6982\u8981<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u7814\u7a76\u30c7\u30b6\u30a4\u30f3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Mahajan\u3089\u306f\u3001\u7c73\u56fd\u306e67\u533b\u7642\u6a5f\u95a2\u304b\u3089\u69cb\u6210\u3055\u308c\u308bTriNetX\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u96fb\u5b50\u30ab\u30eb\u30c6\u30c7\u30fc\u30bf\u3092\u4f7f\u7528\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5bfe\u8c61\u671f\u9593\u306f2020\uff5e2025\u5e74\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u306b\u306f\u3001target trial emulation\uff08\u6a19\u7684\u8a66\u9a13\u30a8\u30df\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\uff09\u304c\u63a1\u7528\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u3001\u89b3\u5bdf\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3066\u3001\u53ef\u80fd\u306a\u9650\u308a\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306b\u8fd1\u3044\u7814\u7a76\u6761\u4ef6\u3092\u518d\u73fe\u3059\u308b\u624b\u6cd5\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u60a3\u8005\u3092\u5b9f\u969b\u306b\u7121\u4f5c\u70ba\u5272\u4ed8\u3057\u305f\u7814\u7a76\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u5bfe\u8c61\u60a3\u8005<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5bfe\u8c61\u306f\u3001SLE\u3068\u8a3a\u65ad\u3055\u308c\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u307e\u305f\u306f\u30d9\u30ea\u30e0\u30de\u30d6\u3092\u65b0\u898f\u306b\u958b\u59cb\u3057\u305f\u6210\u4eba\u60a3\u8005\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u85ac\u5264\u958b\u59cb\u524d\u306b\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u65e2\u5f80\u304c\u3042\u308b\u60a3\u8005\u306f\u9664\u5916\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u6cbb\u7642\u9069\u5fdc\u306e\u9055\u3044\u306b\u3088\u308b\u4ea4\u7d61\u3092\u6e1b\u3089\u3059\u76ee\u7684\u3067\u3001\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3092\u6709\u3059\u308b\u60a3\u8005\u3082\u9664\u5916\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30de\u30c3\u30c1\u30f3\u30b0\u524d\u306e\u60a3\u8005\u6570\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa4\uff1a1,091\u4eba<\/li>\n\n\n\n<li>\u30d9\u30ea\u30e0\u30de\u30d6\u7fa4\uff1a7,492\u4eba<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u50be\u5411\u30b9\u30b3\u30a2\u30de\u30c3\u30c1\u30f3\u30b0\u5f8c\u306f\u3001\u5404\u7fa41,084\u4eba\u3001\u5408\u8a082,168\u4eba\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u60a3\u8005\u80cc\u666f<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30de\u30c3\u30c1\u30f3\u30b0\u5f8c\u306e\u5e73\u5747\u5e74\u9f62\u306f\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa445.6\u6b73\u3001\u30d9\u30ea\u30e0\u30de\u30d6\u7fa446.0\u6b73\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5973\u6027\u306f\u4e21\u7fa4\u3068\u3082\u7d0494\uff05\u3092\u5360\u3081\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u8840\u5727\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u7cd6\u5c3f\u75c5\u3001\u814e\u6a5f\u80fd\u3001\u4f75\u7528\u85ac\u306a\u3069\u306b\u3064\u3044\u3066\u3082\u3001\u30de\u30c3\u30c1\u30f3\u30b0\u5f8c\u306e\u7fa4\u9593\u5dee\u306f\u304a\u304a\u3080\u306d\u5c0f\u3055\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u8a55\u4fa1\u9805\u76ee<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f\u3001\u5fc3\u8840\u7ba1\u6b7b\u3001\u8133\u5352\u4e2d\u3001\u5fc3\u7b4b\u6897\u585e\u3092\u542b\u3080\u4e3b\u8981\u5fc3\u8840\u7ba1\u6709\u5bb3\u4e8b\u8c61\uff08MACE\uff09\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u526f\u6b21\u8a55\u4fa1\u9805\u76ee\u3068\u3057\u3066\u3001\u5fc3\u4e0d\u5168\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\u3001\u8133\u5352\u4e2d\u3001\u5168\u6b7b\u4ea1\u306a\u3069\u304c\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8ffd\u8de1\u671f\u9593\u306f\u6700\u95773\u5e74\u9593\u3067\u3001\u4e2d\u592e\u5024\u306f\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa42.2\u5e74\u3001\u30d9\u30ea\u30e0\u30de\u30d6\u7fa42.8\u5e74\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"548\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-67-548x600.png\" alt=\"SLE\u60a3\u8005\u306b\u304a\u3051\u308b\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u3068\u30d9\u30ea\u30e0\u30de\u30d6\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u6bd4\u8f03\u7814\u7a76\u306e\u60a3\u8005\u9078\u629e\u3068\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u3002\" class=\"wp-image-10048\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-67-548x600.png 548w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-67-274x300.png 274w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-67-768x840.png 768w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-67.png 800w\" sizes=\"auto, (max-width: 548px) 100vw, 548px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1aTriNetX\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u96fb\u5b50\u30ab\u30eb\u30c6\u30c7\u30fc\u30bf\u304b\u3089\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u307e\u305f\u306f\u30d9\u30ea\u30e0\u30de\u30d6\u3092\u958b\u59cb\u3057\u305fSLE\u60a3\u8005\u3092\u62bd\u51fa\u3057\u305f\u3002\u50be\u5411\u30b9\u30b3\u30a2\u30de\u30c3\u30c1\u30f3\u30b0\u5f8c\u3001\u5404\u7fa41,084\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u3066\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u767a\u751f\u30ea\u30b9\u30af\u3092\u6bd4\u8f03\u3057\u305f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c4\u7ae0\uff0e\u7814\u7a76\u7d50\u679c\uff1a\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa4\u3067\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u304c\u5c11\u306a\u304b\u3063\u305f<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u4e3b\u8981\u5fc3\u8840\u7ba1\u6709\u5bb3\u4e8b\u8c61\uff08MACE\uff09<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">MACE\u306e\u767a\u751f\u6570\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa4\uff1a26\u4f8b\uff0f1,084\u4eba<\/li>\n\n\n\n<li>\u30d9\u30ea\u30e0\u30de\u30d6\u7fa4\uff1a57\u4f8b\uff0f1,084\u4eba<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u30cf\u30b6\u30fc\u30c9\u6bd4\uff08HR\uff09\u306f0.65\uff0895\uff05\u4fe1\u983c\u533a\u95930.37\u20130.89\uff09\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa4\u3067\u306f\u3001\u30d9\u30ea\u30e0\u30de\u30d6\u7fa4\u3068\u6bd4\u8f03\u3057\u3066MACE\u306e\u30cf\u30b6\u30fc\u30c9\u304c\u7d0435\uff05\u4f4e\u3044\u3068\u3044\u3046\u95a2\u9023\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u5fc3\u4e0d\u5168<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5fc3\u4e0d\u5168\u306e\u767a\u751f\u6570\u306f\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa420\u4f8b\u3001\u30d9\u30ea\u30e0\u30de\u30d6\u7fa459\u4f8b\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">HR\u306f0.55\uff0895\uff05\u4fe1\u983c\u533a\u95930.39\u20130.75\uff09\u3067\u3042\u308a\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa4\u3067\u5fc3\u4e0d\u5168\u306e\u767a\u751f\u30ea\u30b9\u30af\u304c\u4f4e\u3044\u3068\u3044\u3046\u95a2\u9023\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u5fc3\u4e0d\u5168\u304c\u7279\u306b\u6ce8\u76ee\u3055\u308c\u308b\u7d50\u679c\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u5fc3\u7b4b\u6897\u585e<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5fc3\u7b4b\u6897\u585e\u306e\u767a\u751f\u6570\u306f\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa412\u4f8b\u3001\u30d9\u30ea\u30e0\u30de\u30d6\u7fa423\u4f8b\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">HR\u306f0.63\uff0895\uff05\u4fe1\u983c\u533a\u95930.40\u20130.91\uff09\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u8133\u5352\u4e2d<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u865a\u8840\u6027\u307e\u305f\u306f\u51fa\u8840\u6027\u8133\u5352\u4e2d\u306e\u767a\u751f\u6570\u306f\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa412\u4f8b\u3001\u30d9\u30ea\u30e0\u30de\u30d6\u7fa427\u4f8b\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">HR\u306f0.50\uff0895\uff05\u4fe1\u983c\u533a\u95930.26\u20130.94\uff09\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u306a\u304a\u3001\u7814\u7a76\u8981\u65e8\u3067\u306f\u865a\u8840\u6027\u8133\u5352\u4e2d\u306b\u3064\u3044\u3066\u540c\u3058HR\u304c\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u672c\u6587\u306e\u8a55\u4fa1\u9805\u76ee\u304a\u3088\u3073\u7d50\u679c\u8868\u3067\u306f\u865a\u8840\u6027\u30fb\u51fa\u8840\u6027\u8133\u5352\u4e2d\u3092\u5408\u308f\u305b\u305f\u7d50\u679c\u3068\u3057\u3066\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2464 \u9759\u8108\u8840\u6813\u585e\u6813\u75c7\u3068\u5168\u6b7b\u4ea1<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\u306eHR\u306f0.82\uff0895\uff05\u4fe1\u983c\u533a\u95930.40\u20131.64\uff09\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u76ae\u819a\u75c7\u72b6\u3001\u95a2\u7bc0\u708e\u3001\u814e\u75c5\u5909\u3001\u904e\u53bb\u306e\u6cbb\u7642\u6b74\u306a\u3069\u304c\u85ac\u5264\u9078\u629e\u306b\u5f71\u97ff\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u60a3\u8005\u3092\u9664\u5916\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u6b8b\u4f59\u4ea4\u7d61\u306e\u53ef\u80fd\u6027\u306f\u6b8b\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 SLE\u75be\u60a3\u6d3b\u52d5\u6027\u306e\u60c5\u5831\u304c\u9650\u5b9a\u7684<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">SLEDAI\u306a\u3069\u306e\u75be\u60a3\u6d3b\u52d5\u6027\u6307\u6a19\u3084\u3001\u81d3\u5668\u969c\u5bb3\u306e\u7a0b\u5ea6\u3001\u85ac\u5264\u6295\u4e0e\u91cf\u306b\u95a2\u3059\u308b\u60c5\u5831\u304c\u5341\u5206\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u75be\u60a3\u6d3b\u52d5\u6027\u3084\u7d2f\u7a4d\u30b9\u30c6\u30ed\u30a4\u30c9\u66dd\u9732\u91cf\u306e\u9055\u3044\u304c\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306b\u5f71\u97ff\u3057\u305f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u8ffd\u8de1\u671f\u9593\u306e\u9055\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8ffd\u8de1\u671f\u9593\u4e2d\u592e\u5024\u306f\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u7fa42.2\u5e74\u3001\u30d9\u30ea\u30e0\u30de\u30d6\u7fa42.8\u5e74\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Cox\u56de\u5e30\u5206\u6790\u306b\u3088\u3063\u3066\u8ffd\u8de1\u6642\u9593\u306f\u8003\u616e\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u8ffd\u8de1\u671f\u9593\u306e\u9055\u3044\u3084\u60c5\u5831\u3092\u4f34\u3046\u6253\u3061\u5207\u308a\u306e\u5f71\u97ff\u304c\u5b8c\u5168\u306b\u89e3\u6d88\u3055\u308c\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2464 \u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u767a\u751f\u6570\u304c\u5c11\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306e\u767a\u751f\u6570\u306f\u5408\u8a0883\u4f8b\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u500b\u5225\u30a4\u30d9\u30f3\u30c8\u306e\u767a\u751f\u6570\u306f\u3055\u3089\u306b\u5c11\u306a\u304f\u3001\u63a8\u5b9a\u5024\u306e\u4e0d\u78ba\u5b9f\u6027\u3084\u5076\u7136\u306b\u3088\u308b\u5f71\u97ff\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2465 \u30eb\u30fc\u30d7\u30b9\u814e\u708e\u60a3\u8005\u3078\u306e\u4e00\u822c\u5316\u306f\u3067\u304d\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u60a3\u8005\u304c\u9664\u5916\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001\u814e\u75c5\u5909\u3092\u6709\u3059\u308bSLE\u60a3\u8005\u306b\u5bfe\u3057\u3066\u540c\u69d8\u306e\u7d50\u679c\u304c\u5f97\u3089\u308c\u308b\u304b\u306f\u4e0d\u660e\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c8\u7ae0\uff0e\u4eca\u56de\u306e\u7814\u7a76\u304b\u3089\u81e8\u5e8a\u3067\u4f55\u304c\u5909\u308f\u308b\u306e\u304b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7814\u7a76\u306f\u3001SLE\u306e\u751f\u7269\u5b66\u7684\u88fd\u5264\u9078\u629e\u306b\u304a\u3044\u3066\u3001\u75be\u60a3\u6d3b\u52d5\u6027\u3084\u81d3\u5668\u75c5\u5909\u3060\u3051\u3067\u306a\u304f\u3001\u9577\u671f\u7684\u306a\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306b\u3082\u6ce8\u76ee\u3059\u308b\u5fc5\u8981\u6027\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u304c\u9ad8\u3044SLE\u60a3\u8005\u306b\u5bfe\u3057\u3066\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u306e\u5fc3\u8840\u7ba1\u5b89\u5168\u6027\u3084\u6f5c\u5728\u7684\u306a\u4fdd\u8b77\u4f5c\u7528\u3092\u691c\u8a3c\u3059\u308b\u4fa1\u5024\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u73fe\u6642\u70b9\u3067\u306f\u4eca\u56de\u306e\u7814\u7a76\u306e\u307f\u3092\u6839\u62e0\u306b\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u4e88\u9632\u3092\u76ee\u7684\u3068\u3057\u3066\u30d9\u30ea\u30e0\u30de\u30d6\u3088\u308a\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u3092\u512a\u5148\u3059\u308b\u3053\u3068\u306f\u63a8\u5968\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5b9f\u969b\u306e\u6cbb\u7642\u9078\u629e\u3067\u306f\u3001\u76ae\u819a\u30fb\u95a2\u7bc0\u30fb\u814e\u81d3\u306a\u3069\u306e\u81d3\u5668\u75c5\u5909\u3001\u75be\u60a3\u6d3b\u52d5\u6027\u3001\u611f\u67d3\u75c7\u30ea\u30b9\u30af\u3001\u65e2\u5f80\u6cbb\u7642\u3001\u4f75\u5b58\u75be\u60a3\u3001\u60a3\u8005\u3055\u3093\u306e\u5e0c\u671b\u306a\u3069\u3092\u7dcf\u5408\u7684\u306b\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u306b\u306f\u3001SLE\u306e\u708e\u75c7\u3092\u9069\u5207\u306b\u5236\u5fa1\u3059\u308b\u3053\u3068\u306b\u52a0\u3048\u3001\u8840\u5727\u3001\u8102\u8cea\u3001\u8840\u7cd6\u3001\u55ab\u7159\u3001\u814e\u6a5f\u80fd\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u66dd\u9732\u306a\u3069\u306e\u7ba1\u7406\u304c\u5f15\u304d\u7d9a\u304d\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u73fe\u5728\u306e\u6cbb\u7642\u6226\u7565\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-3990\/\" target=\"_blank\" rel=\"noopener\">ACR\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u89e3\u8aac<\/a>\u3092\u3054\u53c2\u7167\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c9\u7ae0\uff0e\u307e\u3068\u3081<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">2026\u5e74\u306b\u5831\u544a\u3055\u308c\u305f\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001SLE\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u958b\u59cb\u7fa4\u306f\u30d9\u30ea\u30e0\u30de\u30d6\u958b\u59cb\u7fa4\u3088\u308a\u3082\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u767a\u751f\u30ea\u30b9\u30af\u304c\u4f4e\u3044\u3068\u3044\u3046\u95a2\u9023\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u3001\u5fc3\u4e0d\u5168\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\u3001MACE\u3067\u6709\u610f\u306a\u5dee\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\u3084\u5168\u6b7b\u4ea1\u3067\u306f\u660e\u78ba\u306a\u5dee\u306f\u793a\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u7814\u7a76\u306f\u3001I\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u7d4c\u8def\u3068SLE\u306e\u5fc3\u8840\u7ba1\u969c\u5bb3\u3068\u306e\u95a2\u4fc2\u3092\u8003\u3048\u308b\u3046\u3048\u3067\u8208\u5473\u6df1\u3044\u77e5\u898b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u89b3\u5bdf\u7814\u7a76\u3067\u3042\u308b\u3053\u3068\u3001\u75be\u60a3\u6d3b\u52d5\u6027\u3084\u85ac\u5264\u9078\u629e\u306b\u4f34\u3046\u6b8b\u4f59\u4ea4\u7d61\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u304b\u3089\u3001\u7d50\u679c\u306f\u4eee\u8aac\u751f\u6210\u7684\u306b\u89e3\u91c8\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u5f8c\u3001\u524d\u5411\u304d\u7814\u7a76\u3084\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306b\u3088\u308b\u691c\u8a3c\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u95a2\u9023\u8a18\u4e8b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1\uff0e<\/strong><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-1987\/\" target=\"_blank\" rel=\"noopener\"><strong>\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\uff1a\u81e8\u5e8a\u30a2\u30c3\u30d7\u30c7\u30fc\u30c8<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u306e\u75c5\u614b\u3001\u8a3a\u65ad\u3001\u6cbb\u7642\u306b\u3064\u3044\u3066\u7dcf\u5408\u7684\u306b\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u306e\u7814\u7a76\u3092\u7406\u89e3\u3059\u308b\u3046\u3048\u3067\u91cd\u8981\u306a\u3001SLE\u306e\u514d\u75ab\u7570\u5e38\u3084\u81d3\u5668\u969c\u5bb3\u306e\u57fa\u790e\u77e5\u8b58\u3092\u6574\u7406\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2\uff0e<\/strong><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-3990\/\" target=\"_blank\" rel=\"noopener\"><strong>ACR\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u89e3\u8aac<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u306b\u5bfe\u3059\u308b\u6700\u65b0\u306e\u6cbb\u7642\u6226\u7565\u3068\u85ac\u5264\u9078\u629e\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002\u30a2\u30cb\u30d5\u30ed\u30eb\u30de\u30d6\u3084\u30d9\u30ea\u30e0\u30de\u30d6\u306e\u6cbb\u7642\u4e0a\u306e\u4f4d\u7f6e\u3065\u3051\u3092\u7406\u89e3\u3059\u308b\u969b\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>3\uff0e<\/strong><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-8775\/\" target=\"_blank\" rel=\"noopener\"><strong>SLE\u30fb\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306e\u6700\u65b0\u6cbb\u7642\u6226\u7565\uff5c2024\uff5e2026\u5e74\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3092\u542b\u3080SLE\u306e\u6cbb\u7642\u6226\u7565\u306b\u3064\u3044\u3066\u3001\u8fd1\u5e74\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u8e0f\u307e\u3048\u3066\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u6bd4\u8f03\u7814\u7a76\u3067\u306f\u9664\u5916\u3055\u308c\u305f\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u60a3\u8005\u306e\u6cbb\u7642\u3092\u8003\u3048\u308b\u3046\u3048\u3067\u3082\u53c2\u8003\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u5f53\u9662\u3067\u306eSLE\u8a3a\u7642\u306b\u3064\u3044\u3066<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u3001\u30ea\u30a6\u30de\u30c1\u5c02\u9580\u533b\u30fb\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u304c\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\u3092\u542b\u3080\u81a0\u539f\u75c5\u306e\u8a3a\u7642\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u3067\u306f\u3001\u95a2\u7bc0\u75c7\u72b6\u3084\u76ae\u819a\u75c7\u72b6\u3060\u3051\u3067\u306a\u304f\u3001\u814e\u6a5f\u80fd\u3001\u8840\u5727\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u7cd6\u5c3f\u75c5\u306a\u3069\u3001\u5168\u8eab\u306e\u72b6\u614b\u3092\u7d99\u7d9a\u7684\u306b\u8a55\u4fa1\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f53\u9662\u3067\u306f\u3001\u75be\u60a3\u6d3b\u52d5\u6027\u306e\u8a55\u4fa1\u306b\u52a0\u3048\u3066\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3084\u4f75\u5b58\u75be\u60a3\u3082\u542b\u3081\u305f\u7dcf\u5408\u7684\u306a\u7ba1\u7406\u3092\u91cd\u8996\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u5ea6\u306a\u5c02\u9580\u7684\u6cbb\u7642\u3084\u5165\u9662\u7ba1\u7406\u304c\u5fc5\u8981\u306a\u5834\u5408\u306b\u306f\u3001\u9069\u5207\u306a\u5c02\u9580\u533b\u7642\u6a5f\u95a2\u3068\u9023\u643a\u3057\u3066\u8a3a\u7642\u3092\u9032\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u67cf\u5e02\u30fb\u6211\u5b6b\u5b50\u5e02\u5468\u8fba\u3067SLE\u3084\u81a0\u539f\u75c5\u306b\u3064\u3044\u3066\u3054\u76f8\u8ac7\u306e\u3042\u308b\u65b9\u306f\u3001\u5f53\u9662\u307e\u3067\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<ol start=\"1\" class=\"wp-block-list\">\n<li>Mahajan A, Whittelsey M, Vleugels RA, et al. Anifrolumab Versus Belimumab for Cardiovascular Disease Risk in Systemic Lupus Erythematosus. Arthritis Rheumatol. 2026. doi:10.1002\/art.70293.<a href=\"https:\/\/doi.org\/10.1002\/art.70293\">https:\/\/doi.org\/10.1002\/art.70293<\/a><\/li>\n\n\n\n<li>Kirchler C, Husar-Memmer E, Rappersberger K, et al. Type I Interferon as cardiovascular risk factor in systemic and cutaneous lupus erythematosus: a systematic review. Autoimmun Rev. 2021;20(5):102794.<a href=\"https:\/\/doi.org\/10.1016\/j.autrev.2021.102794\">https:\/\/doi.org\/10.1016\/j.autrev.2021.102794<\/a><\/li>\n\n\n\n<li>Casey KA, Smith MA, Sinibaldi D, et al. Modulation of cardiometabolic disease markers by type I interferon inhibition in systemic lupus erythematosus. Arthritis Rheumatol. 2021;73(3):459\u2013471.<a href=\"https:\/\/doi.org\/10.1002\/art.41518\">https:\/\/doi.org\/10.1002\/art.41518<\/a><\/li>\n\n\n\n<li>Hern\u00e1n MA, Wang W, Leaf DE. Target trial emulation: a framework for causal inference from observational data. 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