{"id":10060,"date":"2026-11-13T13:45:13","date_gmt":"2026-11-13T04:45:13","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=10060"},"modified":"2026-11-13T13:47:36","modified_gmt":"2026-11-13T04:47:36","slug":"cerebral-syphilitic-gumma-neurosyphilis-nejm-2026","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/cerebral-syphilitic-gumma-neurosyphilis-nejm-2026\/","title":{"rendered":"\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\uff08Cerebral Syphilitic Gumma\uff09\uff5c\u8133\u816b\u760d\u306b\u985e\u4f3c\u3057\u305f\u795e\u7d4c\u6885\u6bd2\u306e\u4e00\u4f8b\u3010NEJM 2026\u3011"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u8133\u306b\u816b\u7624\u6027\u75c5\u5909\u304c\u898b\u3064\u304b\u3063\u305f\u5834\u5408\u3001\u8133\u816b\u760d\u3084\u60aa\u6027\u30ea\u30f3\u30d1\u816b\u3001\u8ee2\u79fb\u6027\u8133\u816b\u760d\u306a\u3069\u304c\u9451\u5225\u8a3a\u65ad\u306b\u6319\u304c\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u611f\u67d3\u75c7\u306b\u3088\u3063\u3066\u8133\u816b\u760d\u306b\u985e\u4f3c\u3057\u305f\u753b\u50cf\u6240\u898b\u304c\u51fa\u73fe\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u4e00\u3064\u304c\u3001\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\uff08cerebral syphilitic gumma\uff09\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6885\u6bd2\u306f\u6885\u6bd2\u30c8\u30ec\u30dd\u30cd\u30fc\u30de\uff08Treponema pallidum\uff09\u306b\u3088\u308b\u611f\u67d3\u75c7\u3067\u3042\u308a\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306b\u611f\u67d3\u304c\u53ca\u3076\u3068\u795e\u7d4c\u6885\u6bd2\u3092\u767a\u75c7\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u6885\u6bd2\u306e\u81e8\u5e8a\u50cf\u306f\u591a\u5f69\u3067\u3001\u9ac4\u819c\u708e\u3001\u8133\u8840\u7ba1\u969c\u5bb3\u3001\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u306a\u3069\u3092\u5448\u3057\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u307e\u308c\u3067\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u8133\u5b9f\u8cea\u3084\u9ac4\u819c\u306b\u8089\u82bd\u816b\u6027\u75c5\u5909\u3092\u5f62\u6210\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2026\u5e745\u6708\u3001New England Journal of Medicine\uff08NEJM\uff09\u306e\u300cImages in Clinical 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class=\"wp-block-paragraph\">\u3053\u306e\u3088\u3046\u306a\u753b\u50cf\u6240\u898b\u3067\u306f\u3001\u539f\u767a\u6027\u8133\u816b\u760d\u3001\u8ee2\u79fb\u6027\u8133\u816b\u760d\u3001\u60aa\u6027\u30ea\u30f3\u30d1\u816b\u3001\u611f\u67d3\u6027\u8089\u82bd\u816b\u306a\u3069\u3092\u9451\u5225\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u3001\u786c\u819c\u306b\u8fd1\u63a5\u3059\u308b\u9020\u5f71\u75c5\u5909\u3067\u306f\u9ac4\u819c\u816b\u306a\u3069\u3082\u9451\u5225\u306b\u6319\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u3082\u3001\u753b\u50cf\u6240\u898b\u306e\u307f\u3067\u6885\u6bd2\u6027\u75c5\u5909\u3068\u8a3a\u65ad\u3059\u308b\u3053\u3068\u306f\u56f0\u96e3\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"334\" height=\"258\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-69.png\" alt=\"\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u306e\u6cbb\u7642\u524dMRI\u3002\u53f3\u524d\u982d\u982d\u9802\u8449\u306e\u5927\u8133\u938c\u8fd1\u508d\u306b\u9020\u5f71\u75c5\u5909\u3092\u8a8d\u3081\u308b\u3002\" class=\"wp-image-10061\"\/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1a \u53f3\u524d\u982d\u982d\u9802\u8449\u306e\u5927\u8133\u938c\u306b\u96a3\u63a5\u3059\u308b\u9020\u5f71\u75c5\u5909\u3068\u5e83\u7bc4\u306a\u5468\u56f2\u6d6e\u816b\u3092\u8a8d\u3081\u308b\u3002\u9020\u5f71T1\u5f37\u8abf\u77e2\u72b6\u65ad\u753b\u50cf\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c2\u7ae0\uff0e\u8840\u6e05\u691c\u67fb\u3068\u9ac4\u6db2\u691c\u67fb\u304b\u3089\u795e\u7d4c\u6885\u6bd2\u3092\u7591\u3046<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 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class=\"wp-block-paragraph\">\u5f62\u8cea\u7d30\u80de\u6d78\u6f64\u306f\u6885\u6bd2\u6027\u708e\u75c7\u3067\u8a8d\u3081\u3089\u308c\u308b\u91cd\u8981\u306a\u75c5\u7406\u6240\u898b\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u6885\u6bd2\u3067\u306f\u8840\u7ba1\u5468\u56f2\u306e\u708e\u75c7\u3084\u8840\u7ba1\u58c1\u306e\u969c\u5bb3\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3067\u306f\u8840\u7ba1\u708e\u3084\u865a\u8840\u6027\u75c5\u5909\u306e\u5f62\u6210\u306b\u3082\u95a2\u4fc2\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u5f62\u8cea\u7d30\u80de\u6d78\u6f64\u3084\u8840\u7ba1\u708e\u3060\u3051\u3067\u306f\u6885\u6bd2\u306b\u7279\u7570\u7684\u3068\u306f\u3044\u3048\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"345\" height=\"259\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-70.png\" alt=\"\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u306e\u75c5\u7406\u7d44\u7e54\u50cf\u3002\u5f62\u8cea\u7d30\u80de\u6d78\u6f64\u3068\u7d30\u52d5\u8108\u708e\u3092\u8a8d\u3081\u308b\u3002\" class=\"wp-image-10062\"\/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1a \u8133\u75c5\u5909\u306e\u7d44\u7e54\u50cf\u3002\u8c4a\u5bcc\u306a\u5f62\u8cea\u7d30\u80de\u6d78\u6f64\u3068\u7d30\u52d5\u8108\u708e\u3092\u8a8d\u3081\u308b\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u75c5\u5909\u7d44\u7e54\u306e\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272\u306b\u3088\u3063\u3066\u30b9\u30d4\u30ed\u30d8\u30fc\u30bf\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u6240\u898b\u306f\u3001\u75c5\u5909\u3068\u6885\u6bd2\u611f\u67d3\u3068\u306e\u95a2\u9023\u3092\u5f37\u304f\u652f\u6301\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u6e05\u30fb\u9ac4\u6db2\u691c\u67fb\u6240\u898b\u3068\u75c5\u7406\u7d44\u7e54\u6240\u898b\u3092\u7dcf\u5408\u3057\u3001\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\uff08cerebral syphilitic gumma\uff09\u3068\u8a3a\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"327\" height=\"255\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-71.png\" alt=\"\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u306e\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272\u3002\u7d44\u7e54\u5185\u306b\u30b9\u30d4\u30ed\u30d8\u30fc\u30bf\u3092\u8a8d\u3081\u308b\u3002\" class=\"wp-image-10063\"\/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1a \u75c5\u5909\u7d44\u7e54\u306e\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272\u3002\u30b9\u30d4\u30ed\u30d8\u30fc\u30bf\u304c\u691c\u51fa\u3055\u308c\u3001\u6885\u6bd2\u6027\u75c5\u5909\u306e\u8a3a\u65ad\u3092\u652f\u6301\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c4\u7ae0\uff0e\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u3068\u306f\u4f55\u304b<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u6885\u6bd2\u6027\u30b4\u30e0\u816b\u306e\u75c5\u614b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u306f\u3001\u6885\u6bd2\u611f\u67d3\u306b\u4f34\u3063\u3066\u5f62\u6210\u3055\u308c\u308b\u8089\u82bd\u816b\u6027\u306e\u708e\u75c7\u6027\u75c5\u5909\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u822c\u306b\u7b2c\u4e09\u671f\u6885\u6bd2\u306e\u75c5\u614b\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u795e\u7d4c\u6885\u6bd2\u305d\u306e\u3082\u306e\u306f\u611f\u67d3\u5f8c\u306e\u3055\u307e\u3056\u307e\u306a\u6642\u671f\u306b\u767a\u75c7\u3057\u5f97\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u3067\u306f\u3001\u6162\u6027\u7684\u306a\u708e\u75c7\u53cd\u5fdc\u306b\u3088\u3063\u3066\u5c40\u6240\u306b\u816b\u7624\u6027\u75c5\u5909\u304c\u5f62\u6210\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5178\u578b\u7684\u306a\u75c5\u7406\u50cf\u3067\u306f\u3001\u8089\u82bd\u816b\u6027\u708e\u75c7\u3001\u5f62\u8cea\u7d30\u80de\u3092\u542b\u3080\u708e\u75c7\u7d30\u80de\u6d78\u6f64\u3001\u8840\u7ba1\u708e\u3001\u58ca\u6b7b\u6027\u5909\u5316\u306a\u3069\u304c\u8a8d\u3081\u3089\u308c\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u6240\u898b\u304c\u3059\u3079\u3066\u306e\u75c7\u4f8b\u3067\u78ba\u8a8d\u3055\u308c\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306eNEJM\u75c7\u4f8b\u3067\u5b9f\u969b\u306b\u8a18\u8f09\u3055\u308c\u305f\u7279\u5fb4\u306f\u3001\u8c4a\u5bcc\u306a\u5f62\u8cea\u7d30\u80de\u6d78\u6f64\u3001\u7d30\u52d5\u8108\u708e\u3001\u514d\u75ab\u67d3\u8272\u306b\u3088\u308b\u30b9\u30d4\u30ed\u30d8\u30fc\u30bf\u306e\u691c\u51fa\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u306a\u305c\u8133\u816b\u760d\u306b\u985e\u4f3c\u3059\u308b\u306e\u304b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u3067\u306f\u3001\u5c40\u6240\u7684\u306a\u708e\u75c7\u7d30\u80de\u6d78\u6f64\u3068\u8089\u82bd\u816b\u5f62\u6210\u306b\u3088\u3063\u3066\u816b\u7624\u304c\u5f62\u6210\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u708e\u75c7\u306b\u4f34\u3046\u8840\u6db2\u8133\u95a2\u9580\u306e\u969c\u5bb3\u306b\u3088\u3063\u3066\u9020\u5f71\u52b9\u679c\u304c\u51fa\u73fe\u3057\u3001\u5468\u56f2\u306b\u8840\u7ba1\u539f\u6027\u6d6e\u816b\u3092\u4f34\u3046\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001MRI\u3067\u306f\u8133\u816b\u760d\u306b\u985e\u4f3c\u3057\u305f\u753b\u50cf\u6240\u898b\u3092\u5448\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u306e\u3088\u3046\u306b\u5927\u8133\u938c\u4ed8\u8fd1\u306b\u75c5\u5909\u304c\u5b58\u5728\u3059\u308b\u5834\u5408\u306b\u306f\u3001\u9ac4\u819c\u816b\u306a\u3069\u306e\u786c\u819c\u95a2\u9023\u816b\u7624\u3068\u306e\u9451\u5225\u3082\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u753b\u50cf\u4e0a\u306e\u9020\u5f71\u52b9\u679c\u3084\u6d6e\u816b\u3060\u3051\u3067\u3001\u60aa\u6027\u816b\u760d\u3068\u611f\u67d3\u6027\u8089\u82bd\u816b\u3092\u78ba\u5b9f\u306b\u533a\u5225\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u795e\u7d4c\u6885\u6bd2\u306e\u591a\u5f69\u306a\u81e8\u5e8a\u50cf<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u6885\u6bd2\u306f\u3001\u6885\u6bd2\u30c8\u30ec\u30dd\u30cd\u30fc\u30de\u306b\u3088\u308b\u4e2d\u67a2\u795e\u7d4c\u7cfb\u611f\u67d3\u306b\u4f34\u3046\u75c5\u614b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u81e8\u5e8a\u7684\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u75c5\u578b\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u9ac4\u819c\u578b\u795e\u7d4c\u6885\u6bd2<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u982d\u75db\u3001\u9ac4\u819c\u523a\u6fc0\u75c7\u72b6\u3001\u8133\u795e\u7d4c\u969c\u5bb3\u306a\u3069\u3092\u5448\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u9ac4\u819c\u8840\u7ba1\u578b\u795e\u7d4c\u6885\u6bd2<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u7ba1\u708e\u3084\u8840\u7ba1\u969c\u5bb3\u3092\u4ecb\u3057\u3066\u8133\u6897\u585e\u3092\u767a\u75c7\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5b9f\u8cea\u578b\u795e\u7d4c\u6885\u6bd2<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9032\u884c\u9ebb\u75fa\u3084\u810a\u9ac4\u7646\u306a\u3069\u3001\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u3001\u7cbe\u795e\u75c7\u72b6\u3001\u611f\u899a\u969c\u5bb3\u3001\u6b69\u884c\u969c\u5bb3\u306a\u3069\u3092\u5448\u3059\u308b\u75c5\u578b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30b4\u30e0\u816b\u6027\u75c5\u5909<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u5b9f\u8cea\u3084\u9ac4\u819c\u306b\u816b\u7624\u6027\u75c5\u5909\u3092\u5f62\u6210\u3059\u308b\u3001\u307e\u308c\u306a\u75c5\u614b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u75c7\u4f8b\u306f\u3001\u3053\u306e\u30b4\u30e0\u816b\u6027\u75c5\u5909\u306b\u8a72\u5f53\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c5\u7ae0\uff0e\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u306e\u9451\u5225\u8a3a\u65ad<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133MRI\u3067\u9020\u5f71\u52b9\u679c\u3092\u4f34\u3046\u816b\u7624\u6027\u75c5\u5909\u3092\u8a8d\u3081\u305f\u5834\u5408\u3001\u611f\u67d3\u75c7\u3060\u3051\u3067\u306a\u304f\u60aa\u6027\u816b\u760d\u3084\u514d\u75ab\u708e\u75c7\u6027\u75be\u60a3\u3082\u8003\u3048\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u8133\u816b\u760d<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u81a0\u816b\u3001\u8ee2\u79fb\u6027\u8133\u816b\u760d\u3001\u60aa\u6027\u30ea\u30f3\u30d1\u816b\u306a\u3069\u304c\u9451\u5225\u306b\u6319\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9020\u5f71\u30d1\u30bf\u30fc\u30f3\u3001\u75c5\u5909\u306e\u5206\u5e03\u3001\u62e1\u6563\u5f37\u8abf\u753b\u50cf\u3001\u5468\u56f2\u6d6e\u816b\u306e\u7a0b\u5ea6\u306a\u3069\u3092\u7dcf\u5408\u7684\u306b\u8a55\u4fa1\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u816b\u760d\u306b\u985e\u4f3c\u3057\u305f\u753b\u50cf\u6240\u898b\u3092\u5448\u3059\u308b\u75be\u60a3\u3068\u3057\u3066\u3001\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u75c5\u5909\u3082\u91cd\u8981\u3067\u3059\u3002\u591a\u767a\u6027\u786c\u5316\u75c7\u306b\u3088\u308b\u816b\u7624\u6027\u75c5\u5909\u3068\u3001\u305d\u306e\u9451\u5225\u306b\u5f79\u7acb\u3064MRI\u6240\u898b\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/late-onset-multiple-sclerosis-tumefactive-demyelination-nejm-2026\/\" target=\"_blank\" rel=\"noopener\">\u9ad8\u9f62\u767a\u75c7\u306e\u591a\u767a\u6027\u786c\u5316\u75c7\u3068\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u75c5\u5909\uff5cNEJM 2026<\/a>\u3067\u8a73\u3057\u304f\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u9ac4\u819c\u816b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5927\u8133\u938c\u3084\u786c\u819c\u306b\u8fd1\u63a5\u3059\u308b\u816b\u7624\u3067\u306f\u3001\u9ac4\u819c\u816b\u304c\u91cd\u8981\u306a\u9451\u5225\u8a3a\u65ad\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u3082\u786c\u819c\u306b\u63a5\u3059\u308b\u75c5\u5909\u3068\u3057\u3066\u51fa\u73fe\u3059\u308b\u5834\u5408\u304c\u3042\u308a\u3001\u753b\u50cf\u3060\u3051\u3067\u306f\u533a\u5225\u304c\u96e3\u3057\u3044\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u611f\u67d3\u6027\u75c5\u5909<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u81bf\u760d\u3001\u7d50\u6838\u816b\u3001\u771f\u83cc\u6027\u8089\u82bd\u816b\u306a\u3069\u3082\u9451\u5225\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u514d\u75ab\u6291\u5236\u72b6\u614b\u3084\u611f\u67d3\u30ea\u30b9\u30af\u3001\u9ac4\u6db2\u6240\u898b\u3001\u5fae\u751f\u7269\u5b66\u7684\u691c\u67fb\u306a\u3069\u304c\u8a3a\u65ad\u306e\u624b\u304c\u304b\u308a\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u975e\u5178\u578b\u7684\u306a\u611f\u67d3\u75c7\u3067\u306f\u3001\u80cc\u666f\u306b\u3042\u308b\u514d\u75ab\u7570\u5e38\u306e\u8a55\u4fa1\u304c\u8a3a\u65ad\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u6210\u4eba\u767a\u75c7\u306e\u514d\u75ab\u4e0d\u5168\u3068\u64ad\u7a2e\u6027\u611f\u67d3\u75c7\u306e\u8a3a\u65ad\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/anti-ifng-autoantibody-disseminated-ntm-nejm-2026\/\" target=\"_blank\" rel=\"noopener\">\u6297IFN-\u03b3\u81ea\u5df1\u6297\u4f53\u75c7\u5019\u7fa4\u3068\u64ad\u7a2e\u6027\u975e\u7d50\u6838\u6027\u6297\u9178\u83cc\u75c7\uff5cNEJM 2026<\/a>\u3082\u53c2\u8003\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u514d\u75ab\u708e\u75c7\u6027\u75be\u60a3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u3084IgG4\u95a2\u9023\u75be\u60a3\u306a\u3069\u3067\u3082\u3001\u9ac4\u819c\u3084\u8133\u5b9f\u8cea\u306b\u816b\u7624\u6027\u75c5\u5909\u304c\u5f62\u6210\u3055\u308c\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u75be\u60a3\u3067\u3082\u708e\u75c7\u7d30\u80de\u6d78\u6f64\u3092\u8a8d\u3081\u308b\u305f\u3081\u3001\u75c5\u7406\u7d44\u7e54\u306e\u89e3\u91c8\u3067\u306f\u611f\u67d3\u75c7\u306e\u9664\u5916\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u514d\u75ab\u6291\u5236\u7642\u6cd5\u3092\u691c\u8a0e\u3059\u308b\u5834\u5408\u306b\u306f\u3001\u6885\u6bd2\u3092\u542b\u3080\u611f\u67d3\u6027\u75be\u60a3\u3092\u5341\u5206\u306b\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c6\u7ae0\uff0e\u30da\u30cb\u30b7\u30ea\u30f3\u6cbb\u7642\u5f8c\u306b\u795e\u7d4c\u75c7\u72b6\u3068MRI\u6240\u898b\u304c\u6539\u5584<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u30da\u30cb\u30b7\u30ea\u30f3\u306e\u9759\u8108\u5185\u6295\u4e0e\u304c2\u9031\u9593\u884c\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u6cbb\u7642\u5f8c\u306e\u795e\u7d4c\u75c7\u72b6<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6cbb\u7642\u7d42\u4e86\u304b\u30897\u9031\u9593\u5f8c\u306b\u306f\u3001\u5de6\u5074\u306e\u7b4b\u529b\u4f4e\u4e0b\u304c\u6539\u5584\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 MRI\u6240\u898b\u306e\u6539\u5584<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6cbb\u7642\u5f8c\u306eMRI\u3067\u306f\u3001\u8133\u75c5\u5909\u304c\u8457\u660e\u306b\u7e2e\u5c0f\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u3001\u816b\u7624\u6027\u75c5\u5909\u304c\u611f\u67d3\u6027\u30fb\u708e\u75c7\u6027\u75c5\u5909\u3067\u3042\u3063\u305f\u3053\u3068\u3092\u652f\u6301\u3059\u308b\u7d4c\u904e\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"345\" height=\"258\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-72.png\" alt=\"\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u306e\u6cbb\u7642\u5f8cMRI\u3002\u30da\u30cb\u30b7\u30ea\u30f3\u6cbb\u7642\u306b\u3088\u3063\u3066\u8133\u75c5\u5909\u304c\u8457\u660e\u306b\u7e2e\u5c0f\u3057\u3066\u3044\u308b\u3002\" class=\"wp-image-10064\"\/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1a 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class=\"wp-block-paragraph\">\u3053\u306e\u6297\u4f53\u4fa1\u306e\u4f4e\u4e0b\u306f\u6cbb\u7642\u53cd\u5fdc\u3092\u652f\u6301\u3059\u308b\u6240\u898b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u975e\u30c8\u30ec\u30dd\u30cd\u30fc\u30de\u6297\u4f53\u4fa1\u306e\u63a8\u79fb\u3060\u3051\u3067\u795e\u7d4c\u6885\u6bd2\u306e\u5b8c\u5168\u306a\u6cbb\u7652\u3092\u78ba\u5b9a\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u75c7\u72b6\u3001\u8840\u6e05\u5b66\u7684\u53cd\u5fdc\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u305f\u9ac4\u6db2\u691c\u67fb\u3084MRI\u6240\u898b\u306a\u3069\u3092\u7dcf\u5408\u3057\u3066\u7d4c\u904e\u3092\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c7\u7ae0\uff0e\u795e\u7d4c\u6885\u6bd2\u306e\u6cbb\u7642\uff1a\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068\u306e\u95a2\u4fc2<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u6885\u6bd2\u306e\u6cbb\u7642\u3067\u306f\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306b\u5341\u5206\u306a\u85ac\u5264\u6fc3\u5ea6\u3092\u78ba\u4fdd\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CDC\u306e\u6027\u611f\u67d3\u75c7\u6cbb\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3001\u795e\u7d4c\u6885\u6bd2\u306b\u5bfe\u3059\u308b\u6a19\u6e96\u6cbb\u7642\u3068\u3057\u3066\u6c34\u6eb6\u6027\u7d50\u6676\u30da\u30cb\u30b7\u30ea\u30f3G\u306e\u9759\u8108\u5185\u6295\u4e0e\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u63a8\u5968\u3055\u308c\u308b\u6cbb\u7642\u306f\u4ee5\u4e0b\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ul 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class=\"wp-block-paragraph\">\u6297IFN-\u03b3\u81ea\u5df1\u6297\u4f53\u306b\u3088\u308b\u514d\u75ab\u7570\u5e38\u306f\u3001\u64ad\u7a2e\u6027\u975e\u7d50\u6838\u6027\u6297\u9178\u83cc\u75c7\u306a\u3069\u306e\u91cd\u75c7\u611f\u67d3\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u8133\u6885\u6bd2\u6027\u30b4\u30e0\u816b\u3068\u306f\u75c5\u614b\u304c\u7570\u306a\u308a\u307e\u3059\u304c\u3001\u975e\u5178\u578b\u7684\u306a\u611f\u67d3\u75c7\u3092\u8a3a\u65ad\u3059\u308b\u969b\u306b\u3001\u514d\u75ab\u5b66\u7684\u691c\u67fb\u3084\u75c5\u7406\u7d44\u7e54\u6240\u898b\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u91cd\u8981\u6027\u3092\u5b66\u3079\u308b\u75c7\u4f8b\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">3\uff0e<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-8270\/\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u75c5\u614b\u30fb\u8a3a\u65ad\u30fb\u6cbb\u7642\uff5c\u5c02\u9580\u533b\u306b\u3088\u308b\u89e3\u8aac<\/a><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306f\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306b\u708e\u75c7\u6027\u8131\u9ac4\u75c5\u5909\u3092\u5f62\u6210\u3059\u308b\u81ea\u5df1\u514d\u75ab\u6027\u75be\u60a3\u3067\u3059\u3002\u795e\u7d4c\u6885\u6bd2\u3068\u306f\u539f\u56e0\u3082\u6cbb\u7642\u6cd5\u3082\u7570\u306a\u308a\u307e\u3059\u304c\u3001\u4e21\u75be\u60a3\u306e\u81e8\u5e8a\u50cf\u3084MRI\u6240\u898b\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u708e\u75c7\u6027\u75be\u60a3\u306b\u5bfe\u3059\u308b\u9451\u5225\u8a3a\u65ad\u306e\u7406\u89e3\u3092\u6df1\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<\/div><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<ol start=\"1\" class=\"wp-block-list\">\n<li>Xiao K, Si Y. Cerebral Syphilitic Gumma. N Engl J Med. 2026;394:1939.<br><a href=\"https:\/\/doi.org\/10.1056\/NEJMicm2518333\">https:\/\/doi.org\/10.1056\/NEJMicm2518333<\/a><\/li>\n\n\n\n<li>Centers for Disease Control and Prevention. Neurosyphilis, Ocular Syphilis, and Otosyphilis. Sexually Transmitted Infections Treatment Guidelines.<br><a href=\"https:\/\/www.cdc.gov\/std\/treatment-guidelines\/neurosyphilis.htm\">https:\/\/www.cdc.gov\/std\/treatment-guidelines\/neurosyphilis.htm<\/a><\/li>\n\n\n\n<li>Centers for Disease Control and Prevention. Syphilis. Sexually Transmitted Infections Treatment Guidelines.<br><a href=\"https:\/\/www.cdc.gov\/std\/treatment-guidelines\/syphilis.htm\">https:\/\/www.cdc.gov\/std\/treatment-guidelines\/syphilis.htm<\/a><\/li>\n\n\n\n<li>Cerebral syphilitic gumma: a case retrospective report of eight cases. 2024.<br><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11635609\/\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11635609\/<\/a><\/li>\n<\/ol>\n<\/blockquote>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23%\">\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/84f9b1a365bb2c08a7e4b50359f34012-600x600.png\" alt=\"\" class=\"wp-image-8240\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/84f9b1a365bb2c08a7e4b50359f34012-600x600.png 600w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/84f9b1a365bb2c08a7e4b50359f34012-150x150.png 150w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/84f9b1a365bb2c08a7e4b50359f34012-300x300.png 300w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/84f9b1a365bb2c08a7e4b50359f34012-768x768.png 768w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/84f9b1a365bb2c08a7e4b50359f34012.png 800w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:77%\">\n<p 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