{"id":10073,"date":"2026-11-13T21:12:51","date_gmt":"2026-11-13T12:12:51","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=10073"},"modified":"2026-11-13T21:14:31","modified_gmt":"2026-11-13T12:14:31","slug":"blog-sle-inflammatory-myopathy-overlap-vaginal-bleeding-nejm-2026","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/blog-sle-inflammatory-myopathy-overlap-vaginal-bleeding-nejm-2026\/","title":{"rendered":"\u4e0d\u6b63\u6027\u5668\u51fa\u8840\u304b\u3089\u8a3a\u65ad\u3055\u308c\u305fSLE\u30fb\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u30aa\u30fc\u30d0\u30fc\u30e9\u30c3\u30d7\u75c7\u5019\u7fa4\uff5cNEJM 2026\u5e74\u75c7\u4f8b"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">\u91cd\u8981\u8981\u70b9<\/h2>\n\n\n\n<p 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class=\"wp-block-paragraph\">LDH\u4e0a\u6607\u3068\u30cf\u30d7\u30c8\u30b0\u30ed\u30d3\u30f3\u4f4e\u4e0b\u306f\u6eb6\u8840\u3092\u793a\u5506\u3057\u307e\u3059\u304c\u3001\u51fa\u8840\u3084\u8f38\u8840\u306e\u5f71\u97ff\u3082\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u708e\u75c7\u30fb\u514d\u75ab\u5b66\u7684\u7570\u5e38<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>ESR\uff1a88 mm\/\u6642<\/li>\n\n\n\n<li>CRP\uff1a9.9 mg\/L<\/li>\n\n\n\n<li>\u7dcf\u86cb\u767d\uff1a9.2 g\/dL<\/li>\n\n\n\n<li>\u30a2\u30eb\u30d6\u30df\u30f3\uff1a3.2 g\/dL<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">ESR\u304c\u9ad8\u5ea6\u306b\u4e0a\u6607\u3057\u3066\u3044\u308b\u4e00\u65b9\u3001CRP\u306e\u4e0a\u6607\u306f\u6bd4\u8f03\u7684\u8efd\u5ea6\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306eESR\u3068CRP\u306e\u4e56\u96e2\u306f\u3001SLE\u3067\u89b3\u5bdf\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u306e\u6240\u898b\u3060\u3051\u3067SLE\u3068\u8a3a\u65ad\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u305a\u3001\u8ca7\u8840\u3084\u9ad8\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u8840\u75c7\u306a\u3069\u306e\u5f71\u97ff\u3082\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u7b4b\u969c\u5bb3\u3092\u793a\u5506\u3059\u308b\u7570\u5e38<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>CK\uff1a268 U\/L<\/li>\n\n\n\n<li>AST\uff1a111 U\/L<\/li>\n\n\n\n<li>ALT\uff1a64 U\/L<\/li>\n\n\n\n<li>\u8fd1\u4f4d\u7b4b\u512a\u4f4d\u306e\u7b4b\u529b\u4f4e\u4e0b<\/li>\n\n\n\n<li>\u4e0a\u8155\u306e\u7b4b\u840e\u7e2e<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">CK\u4e0a\u6607\u306f\u6bd4\u8f03\u7684\u8efd\u5ea6\u3067\u3057\u305f\u304c\u3001\u7b4b\u529b\u4f4e\u4e0b\u306f\u9855\u8457\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u3067\u306f\u3001CK\u5024\u306e\u9ad8\u3055\u3068\u7b4b\u529b\u4f4e\u4e0b\u306e\u7a0b\u5ea6\u304c\u5fc5\u305a\u3057\u3082\u4e00\u81f4\u3057\u306a\u3044\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u814e\u969c\u5bb3\u3092\u793a\u5506\u3059\u308b\u7570\u5e38<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5c3f\u691c\u67fb\u3067\u306f\u8840\u5c3f\u3068\u86cb\u767d\u5c3f\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u5f8c\u3001\u5c3f\u86cb\u767d\/\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u6bd4\u306f6.51\u306b\u9054\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u306f\u6b63\u5e38\u7bc4\u56f2\u3092\u7dad\u6301\u3057\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u9ad8\u5ea6\u306e\u86cb\u767d\u5c3f\u304c\u5b58\u5728\u3057\u3066\u304a\u308a\u3001\u7cf8\u7403\u4f53\u75be\u60a3\u304c\u5f37\u304f\u7591\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u814e\u6a5f\u80fd\u304c\u6b63\u5e38\u3060\u304b\u3089\u3068\u3044\u3063\u3066\u3001\u6d3b\u52d5\u6027\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3092\u5426\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c3\u7ae0\uff1a\u9451\u5225\u8a3a\u65ad\uff5c\u5168\u8eab\u6027\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3092\u7591\u3046\u7406\u7531<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u6025\u6027\u306e\u5927\u91cf\u51fa\u8840\u3078\u306e\u5bfe\u5fdc\u3068\u4e26\u884c\u3057\u3066\u3001\u6570\u304b\u6708\u304b\u3089\u6570\u5e74\u306b\u308f\u305f\u308b\u5168\u8eab\u75c7\u72b6\u3092\u8aac\u660e\u3067\u304d\u308b\u75be\u60a3\u306e\u691c\u7d22\u304c\u5fc5\u8981\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u91cd\u8981\u306a\u9451\u5225\u75be\u60a3\u306f\u3001\u4ee5\u4e0b\u306e3\u7fa4\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u5168\u8eab\u6027\u81ea\u5df1\u514d\u75ab\u75be\u60a3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u3001\u6df7\u5408\u6027\u7d50\u5408\u7d44\u7e54\u75c5\uff08MCTD\uff09\u3001\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u306a\u3069\u304c\u5019\u88dc\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u4ee5\u4e0b\u306e\u6240\u898b\u304c\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>3\u5e74\u524d\u304b\u3089\u306e\u30ec\u30a4\u30ce\u30fc\u73fe\u8c61<\/li>\n\n\n\n<li>\u9032\u884c\u6027\u306e\u8fd1\u4f4d\u7b4b\u7b4b\u529b\u4f4e\u4e0b<\/li>\n\n\n\n<li>\u8131\u6bdb\u3068\u982d\u76ae\u75c5\u5909<\/li>\n\n\n\n<li>\u767d\u8840\u7403\u6e1b\u5c11\u30fb\u8840\u5c0f\u677f\u6e1b\u5c11<\/li>\n\n\n\n<li>\u9ad8\u5ea6\u306eESR\u4e0a\u6607<\/li>\n\n\n\n<li>\u86cb\u767d\u5c3f\u30fb\u8840\u5c3f<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u3001\u76ae\u819a\u3001\u7b4b\u3001\u8840\u6db2\u3001\u814e\u81d3\u3068\u3044\u3046\u8907\u6570\u81d3\u5668\u306b\u7570\u5e38\u304c\u5b58\u5728\u3057\u3066\u3044\u305f\u70b9\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 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class=\"wp-block-paragraph\">\u767a\u71b1\u3001\u30ea\u30f3\u30d1\u7bc0\u816b\u8139\u3001\u813e\u816b\u306a\u3069\u306f\u611f\u67d3\u75c7\u3067\u3082\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u514d\u75ab\u6291\u5236\u7642\u6cd5\u3092\u958b\u59cb\u3059\u308b\u524d\u306b\u306f\u3001\u611f\u67d3\u75c7\u3084\u60aa\u6027\u816b\u760d\u3092\u9069\u5207\u306b\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u8a3a\u65ad\u4e0a\u306e\u91cd\u8981\u306a\u8003\u3048\u65b9<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u5b50\u5bae\u7b4b\u816b\u306b\u3088\u308b\u51fa\u8840\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u81ea\u4f53\u306f\u6b63\u3057\u3044\u8a3a\u65ad\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u554f\u984c\u306f\u3001\u305d\u308c\u3060\u3051\u3067\u5168\u8eab\u75c7\u72b6\u306e\u3059\u3079\u3066\u3092\u8aac\u660e\u3057\u3088\u3046\u3068\u3059\u308b\u3068\u3001\u80cc\u666f\u306b\u5b58\u5728\u3059\u308b\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3092\u898b\u9003\u3057\u3066\u3057\u307e\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u3064\u306e\u75be\u60a3\u3067\u8aac\u660e\u3067\u304d\u308b\u75c7\u72b6\u3068\u3001\u5225\u306e\u75c5\u614b\u3092\u8003\u3048\u308b\u3079\u304d\u75c7\u72b6\u3092\u533a\u5225\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c4\u7ae0\uff1a\u81ea\u5df1\u6297\u4f53\u691c\u67fb\uff5c\u6297dsDNA\u6297\u4f53\u9670\u6027\u3067\u3082SLE\u306f\u5426\u5b9a\u3067\u304d\u306a\u3044<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u8ffd\u52a0\u691c\u67fb\u3067\u306f\u3001\u4ee5\u4e0b\u306e\u81ea\u5df1\u6297\u4f53\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u967d\u6027\u6240\u898b<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6297\u6838\u6297\u4f53\uff1a1:640\u3001\u6838\u5185\u5747\u8cea\u578b<\/li>\n\n\n\n<li>\u6297Sm\u6297\u4f53<\/li>\n\n\n\n<li>\u6297RNP\u6297\u4f53<\/li>\n\n\n\n<li>\u6297CCP\u6297\u4f53<\/li>\n\n\n\n<li>\u30ea\u30a6\u30de\u30c8\u30a4\u30c9\u56e0\u5b50<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">\u9670\u6027\u307e\u305f\u306f\u5224\u5b9a\u4fdd\u7559\u306e\u6240\u898b<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6297dsDNA\u6297\u4f53\uff1a\u9670\u6027<\/li>\n\n\n\n<li>\u6297SS-B\/La\u6297\u4f53\uff1a\u9670\u6027<\/li>\n\n\n\n<li>\u6297SS-A\/Ro\u6297\u4f53\uff1a\u5224\u5b9a\u4fdd\u7559<\/li>\n\n\n\n<li>\u7b4b\u708e\u95a2\u9023\u30fb\u7279\u7570\u81ea\u5df1\u6297\u4f53\u30d1\u30cd\u30eb\uff1a\u9670\u6027<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u6297Sm\u6297\u4f53\u306fSLE\u306b\u5bfe\u3059\u308b\u7279\u7570\u6027\u304c\u9ad8\u304f\u3001\u672c\u75c7\u4f8b\u306e\u8a3a\u65ad\u3092\u652f\u6301\u3059\u308b\u91cd\u8981\u306a\u6240\u898b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u6297dsDNA\u6297\u4f53\u306f\u9670\u6027\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u3067\u306f\u6297dsDNA\u6297\u4f53\u304c\u8a3a\u65ad\u3084\u75be\u60a3\u6d3b\u52d5\u6027\u8a55\u4fa1\u306b\u6709\u7528\u3067\u3059\u304c\u3001\u3059\u3079\u3066\u306e\u60a3\u8005\u3067\u967d\u6027\u306b\u306a\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001<strong>\u6297dsDNA\u6297\u4f53\u9670\u6027\u3068\u3044\u3046\u7d50\u679c\u3060\u3051\u3067SLE\u3084\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3092\u5426\u5b9a\u3057\u3066\u306f\u3044\u3051\u307e\u305b\u3093\u3002<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u6297RNP\u6297\u4f53\u967d\u6027\u3068\u30ec\u30a4\u30ce\u30fc\u73fe\u8c61\u3001\u7b4b\u708e\u3092\u8a8d\u3081\u305f\u3053\u3068\u304b\u3089MCTD\u3082\u9451\u5225\u306b\u6319\u304c\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u6700\u7d42\u7684\u306b\u306fSLE\u3068\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u305d\u308c\u305e\u308c\u306e\u5206\u985e\u57fa\u6e96\u3092\u6e80\u305f\u3059\u3053\u3068\u304b\u3089\u3001\u4e21\u75be\u60a3\u306e\u30aa\u30fc\u30d0\u30fc\u30e9\u30c3\u30d7\u75c7\u5019\u7fa4\u3068\u8a3a\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u306a\u304a\u3001\u5206\u985e\u57fa\u6e96\u306f\u8a3a\u65ad\u3092\u88dc\u52a9\u3059\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u5b9f\u81e8\u5e8a\u3067\u306f\u75c5\u6b74\u3001\u8eab\u4f53\u6240\u898b\u3001\u81d3\u5668\u75c5\u5909\u3001\u691c\u67fb\u7d50\u679c\u3092\u7dcf\u5408\u3057\u3066\u5224\u65ad\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c5\u7ae0\uff1a\u982d\u76ae\u751f\u691c\uff5c\u8131\u6bdb\u306e\u80cc\u666f\u306b\u5b58\u5728\u3057\u305f\u81ea\u5df1\u514d\u75ab\u6027\u708e\u75c7<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u60a3\u8005\u306e\u8131\u6bdb\u306f\u5f53\u521d\u3001\u91cd\u75c7\u9244\u6b20\u4e4f\u6027\u8ca7\u8840\u306b\u4f34\u3046\u75c7\u72b6\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u982d\u76ae\u751f\u691c\u304b\u3089\u306f\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3092\u793a\u5506\u3059\u308b\u6240\u898b\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u306a\u75c5\u7406\u6240\u898b\u306f\u4ee5\u4e0b\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6bdb\u5305\u306e\u5909\u5316<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6bdb\u5305\u6570\u306e\u6e1b\u5c11\u3068\u5c0f\u578b\u5316\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Interface dermatitis<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8868\u76ae\u304a\u3088\u3073\u6bdb\u5305\u4e0a\u76ae\u306b\u6db2\u72b6\u5909\u6027\u3092\u4f34\u3046\u5883\u754c\u90e8\u76ae\u819a\u708e\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u8272\u7d20\u5931\u8abf<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u771f\u76ae\u306b\u306f\u8272\u7d20\u306e\u6f0f\u51fa\u30fb\u6c88\u7740\u3092\u793a\u3059\u5909\u5316\u304c\u5b58\u5728\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u771f\u76ae\u30e0\u30c1\u30f3\u6c88\u7740<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u771f\u76ae\u306b\u306f\u8457\u660e\u306a\u30e0\u30c1\u30f3\u6c88\u7740\u304c\u8a8d\u3081\u3089\u308c\u3001\u30b3\u30ed\u30a4\u30c9\u9244\u67d3\u8272\u3067\u3082\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u6240\u898b\u306f\u3001\u81ea\u5df1\u514d\u75ab\u6027\u306e\u76ae\u819a\u75c5\u5909\u3092\u652f\u6301\u3059\u308b\u3082\u306e\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u81e8\u5e8a\u7684\u306b\u306f\u5186\u677f\u72b6\u30eb\u30fc\u30d7\u30b9\u3092\u793a\u5506\u3059\u308b\u982d\u76ae\u75c5\u5909\u3068\u5224\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8131\u6bdb\u306f\u9244\u6b20\u4e4f\u3001\u7532\u72b6\u817a\u75be\u60a3\u3001\u85ac\u5264\u3001\u611f\u67d3\u75c7\u306a\u3069\u3067\u3082\u751f\u3058\u307e\u3059\u304c\u3001\u76ae\u819a\u306e\u8272\u8abf\u5909\u5316\u3084\u708e\u75c7\u6027\u75c5\u5909\u3092\u4f34\u3046\u5834\u5408\u306b\u306f\u81a0\u539f\u75c5\u3082\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"404\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-74-404x600.png\" alt=\"SLE\u60a3\u8005\u306e\u982d\u76ae\u751f\u691c\u3067\u8a8d\u3081\u3089\u308c\u305f\u6bdb\u5305\u840e\u7e2e\u3001\u5883\u754c\u90e8\u76ae\u819a\u708e\u3001\u8272\u7d20\u5931\u8abf\u3001\u771f\u76ae\u30e0\u30c1\u30f3\u6c88\u7740\u306e\u75c5\u7406\u753b\u50cf\" class=\"wp-image-10075\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-74-404x600.png 404w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-74-202x300.png 202w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-74.png 552w\" sizes=\"auto, (max-width: 404px) 100vw, 404px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1aNEJM\u539f\u8457Figure 2\u306b\u793a\u3055\u308c\u305f\u982d\u76ae\u751f\u691c\u6240\u898b\u3002\u6bdb\u5305\u306e\u6e1b\u5c11\u3068\u5c0f\u578b\u5316\u3001\u6bdb\u5305\u5468\u56f2\u304a\u3088\u3073\u8868\u76ae\u306e\u5883\u754c\u90e8\u76ae\u819a\u708e\u3001\u8272\u7d20\u5931\u8abf\u3001\u771f\u76ae\u30e0\u30c1\u30f3\u6c88\u7740\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u3053\u308c\u3089\u306e\u7d44\u7e54\u5b66\u7684\u6240\u898b\u306fSLE\u306b\u4f34\u3046\u76ae\u819a\u75c5\u5909\u3092\u652f\u6301\u3057\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c6\u7ae0\uff1a\u30eb\u30fc\u30d7\u30b9\u814e\u708e\uff5c\u814e\u6a5f\u80fd\u6b63\u5e38\u3067\u3082\u9ad8\u5ea6\u306e\u814e\u75c5\u5909\u304c\u5b58\u5728<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u7279\u306b\u91cd\u8981\u306a\u306e\u304c\u814e\u75c5\u5909\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u5024\u306f\u6b63\u5e38\u3067\u3057\u305f\u304c\u3001\u5c3f\u86cb\u767d\/\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u6bd4\u306f6.51\u3068\u9ad8\u5ea6\u306e\u86cb\u767d\u5c3f\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5165\u966214\u65e5\u76ee\u306b\u814e\u751f\u691c\u304c\u65bd\u884c\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u5149\u5b66\u9855\u5fae\u93e1\u6240\u898b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">18\u500b\u306e\u7cf8\u7403\u4f53\u306e\u3046\u30613\u500b\u306b\u8efd\u5ea6\u306e\u7ba1\u5185\u7d30\u80de\u5897\u591a\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u819c\u6027\u75c5\u5909\u3092\u793a\u5506\u3059\u308b\u6c88\u7740\u7269\u3082\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u86cd\u5149\u6297\u4f53\u6cd5<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u7cf8\u7403\u4f53\u306b\u4ee5\u4e0b\u306e\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u30fb\u88dc\u4f53\u6210\u5206\u304c\u6c88\u7740\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>IgG<\/li>\n\n\n\n<li>IgM<\/li>\n\n\n\n<li>IgA<\/li>\n\n\n\n<li>C3<\/li>\n\n\n\n<li>C1q<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3044\u308f\u3086\u308b\u300cfull-house pattern\u300d\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u6240\u898b\u306f\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3067\u7279\u5fb4\u7684\u306b\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001full-house pattern\u306fSLE\u3060\u3051\u306b\u7279\u7570\u7684\u306a\u6240\u898b\u3067\u306f\u306a\u304f\u3001\u81e8\u5e8a\u6240\u898b\u3084\u81ea\u5df1\u6297\u4f53\u691c\u67fb\u3068\u306e\u7d71\u5408\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u96fb\u5b50\u9855\u5fae\u93e1\u6240\u898b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30e1\u30b5\u30f3\u30ae\u30a6\u30e0\u9818\u57df\u3068\u4e0a\u76ae\u4e0b\u306b\u96fb\u5b50\u5bc6\u5ea6\u306e\u9ad8\u3044\u6c88\u7740\u7269\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001tubuloreticular structures\uff08\u7ba1\u72b6\u7db2\u72b6\u5c01\u5165\u4f53\uff09\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306fI\u578b\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u6d3b\u6027\u5316\u3068\u95a2\u9023\u3059\u308b\u8d85\u5fae\u5f62\u614b\u5b66\u7684\u6240\u898b\u3067\u3042\u308a\u3001\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3067\u3082\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6700\u7d42\u7684\u306a\u814e\u75c5\u7406\u8a3a\u65ad<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Class V\uff08\u819c\u6027\u30eb\u30fc\u30d7\u30b9\u814e\u708e\uff09\u512a\u4f4d\u3067\u3001\u8efd\u5ea6\u306eClass III\uff08\u5de3\u72b6\u30eb\u30fc\u30d7\u30b9\u814e\u708e\uff09\u75c5\u5909\u3092\u4f34\u3046\u30eb\u30fc\u30d7\u30b9\u814e\u708e<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u8a3a\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Class V\u75c5\u5909\u306f\u9ad8\u5ea6\u86cb\u767d\u5c3f\u3092\u5448\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u3001Class III\u75c5\u5909\u306e\u5408\u4f75\u306f\u5897\u6b96\u6027\u75c5\u5909\u306e\u5b58\u5728\u3092\u610f\u5473\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u814e\u6a5f\u80fd\u304c\u6b63\u5e38\u3067\u3082\u814e\u751f\u691c\u304c\u75c5\u578b\u306e\u78ba\u5b9a\u3068\u6cbb\u7642\u9078\u629e\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306e\u7d44\u7e54\u5206\u985e\u3068\u6cbb\u7642\u9078\u629e\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-8775\/\">SLE\u30fb\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306e\u6700\u65b0\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068\u6cbb\u7642\u6226\u7565<\/a>\u3067\u3082\u8a73\u3057\u304f\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"443\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-75-443x600.png\" alt=\"SLE\u60a3\u8005\u306e\u814e\u751f\u691c\u75c5\u7406\u753b\u50cf\u3002\u30eb\u30fc\u30d7\u30b9\u814e\u708eClass V\u512a\u4f4d\u3001\u8efd\u5ea6Class III\u75c5\u5909\u3001full-house pattern\u3001\u4e0a\u76ae\u4e0b\u514d\u75ab\u8907\u5408\u4f53\u6c88\u7740\u3001\u7ba1\u72b6\u7db2\u72b6\u5c01\u5165\u4f53\u3092\u793a\u3059\u3002\" class=\"wp-image-10076\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-75-443x600.png 443w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-75-222x300.png 222w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-75.png 544w\" sizes=\"auto, (max-width: 443px) 100vw, 443px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1aNEJM\u539f\u8457Figure 3\u306b\u793a\u3055\u308c\u305f\u814e\u751f\u691c\u6240\u898b\u3002\u5149\u5b66\u9855\u5fae\u93e1\u3067\u306f\u4e00\u90e8\u7cf8\u7403\u4f53\u306b\u7ba1\u5185\u7d30\u80de\u5897\u591a\u304c\u8a8d\u3081\u3089\u308c\u3001\u514d\u75ab\u86cd\u5149\u67d3\u8272\u3067\u306fIgG\u3001IgA\u3001IgM\u3001C3\u3001C1q\u304c\u6c88\u7740\u3059\u308bfull-house pattern\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\u96fb\u5b50\u9855\u5fae\u93e1\u3067\u306f\u4e0a\u76ae\u4e0b\u6c88\u7740\u7269\u3068\u7ba1\u72b6\u7db2\u72b6\u5c01\u5165\u4f53\u3092\u8a8d\u3081\u3001Class V\u512a\u4f4d\u3067\u8efd\u5ea6\u306eClass III\u75c5\u5909\u3092\u4f34\u3046\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3068\u8a3a\u65ad\u3055\u308c\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c7\u7ae0\uff1a\u8840\u5c0f\u677f\u6e1b\u5c11\u306e\u539f\u56e0\uff5cITP\u3068\u5373\u65ad\u3057\u306a\u3044\u3053\u3068\u306e\u91cd\u8981\u6027<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u8840\u5c0f\u677f\u6570\u304c39,000\/\u03bcL\u307e\u3067\u6e1b\u5c11\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u3067\u306f\u514d\u75ab\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\uff08ITP\uff09\u3092\u5408\u4f75\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u5f53\u521d\u306f\u305d\u306e\u53ef\u80fd\u6027\u304c\u8003\u616e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u5c0f\u677f\u95a2\u9023IgM\u6297\u4f53\u306f\u5f37\u967d\u6027\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u3053\u306e\u7d50\u679c\u3060\u3051\u3067ITP\u3068\u8a3a\u65ad\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u8840\u5c0f\u677f\u95a2\u9023\u6297\u4f53\u691c\u67fb\u306e\u9650\u754c<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u5c0f\u677f\u95a2\u9023\u6297\u4f53\u691c\u67fb\u306b\u306f\u3001\u691c\u67fb\u65b9\u6cd5\u306b\u3088\u308b\u7279\u7570\u5ea6\u306e\u9055\u3044\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u6700\u521d\u306b\u884c\u308f\u308c\u305f\u691c\u67fb\u306f\u3001\u8840\u5c0f\u677f\u8868\u9762\u306b\u7d50\u5408\u3057\u305fIgM\u3092\u691c\u51fa\u3059\u308b\u3082\u306e\u3067\u3057\u305f\u304c\u3001\u8840\u5c0f\u677f\u7cd6\u86cb\u767d\u306b\u7279\u7570\u7684\u306a\u6297\u4f53\u3092\u6e2c\u5b9a\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u708e\u75c7\u3084\u9ad8\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u72b6\u614b\u3067\u306f\u3001\u8840\u5c0f\u677f\u306b\u975e\u7279\u7570\u7684\u306b\u7d50\u5408\u3057\u305f\u6297\u4f53\u304c\u691c\u51fa\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u30ea\u30a6\u30de\u30c8\u30a4\u30c9\u56e0\u5b50IgM\u304c\u9ad8\u529b\u4fa1\u3067\u3042\u3063\u305f\u3053\u3068\u304c\u507d\u967d\u6027\u306e\u539f\u56e0\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u8ffd\u52a0\u691c\u67fb\u3067\u5224\u660e\u3057\u305f\u3053\u3068<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u5f8c\u3001\u8840\u5c0f\u677f\u7cd6\u86cb\u767d\u306b\u5bfe\u3059\u308b\u7279\u7570\u7684\u306a\u76f4\u63a5\u6297\u4f53\u691c\u67fb\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u304c\u3001\u7d50\u679c\u306f\u9670\u6027\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u51fa\u8840\u306e\u6539\u5584\u3068\u813e\u816b\u306e\u6d88\u5931\u306b\u4f34\u3063\u3066\u8840\u5c0f\u677f\u6570\u304c\u6b63\u5e38\u5316\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u7d4c\u904e\u304b\u3089\u3001\u8840\u5c0f\u677f\u6e1b\u5c11\u306e\u4e3b\u56e0\u306f\u514d\u75ab\u5b66\u7684\u306a\u8840\u5c0f\u677f\u7834\u58ca\u3067\u306f\u306a\u304f\u3001\u6162\u6027\u51fa\u8840\u306b\u4f34\u3046\u8840\u5c0f\u677f\u6d88\u8cbb\u3068\u813e\u816b\u306b\u3088\u308b\u813e\u5185\u8caf\u7559\u306a\u3069\u306e\u8907\u5408\u7684\u306a\u8981\u56e0\u3068\u5224\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u81e8\u5e8a\u7684\u306a\u6559\u8a13<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u60a3\u8005\u3067\u8840\u5c0f\u677f\u6e1b\u5c11\u3092\u8a8d\u3081\u305f\u5834\u5408\u3001\u305d\u306e\u539f\u56e0\u304c\u5fc5\u305aITP\u3067\u3042\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u5c0f\u677f\u6e1b\u5c11\u306e\u9451\u5225\u3067\u306f\u3001\u4ee5\u4e0b\u3092\u691c\u8a0e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u514d\u75ab\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7<\/li>\n\n\n\n<li>\u51fa\u8840\u3084\u6d88\u8cbb\u306b\u3088\u308b\u8840\u5c0f\u677f\u6e1b\u5c11<\/li>\n\n\n\n<li>\u813e\u6a5f\u80fd\u4ea2\u9032\u30fb\u813e\u5185\u8caf\u7559<\/li>\n\n\n\n<li>\u85ac\u5264\u6027\u8840\u5c0f\u677f\u6e1b\u5c11<\/li>\n\n\n\n<li>\u611f\u67d3\u75c7<\/li>\n\n\n\n<li>\u8840\u6813\u6027\u5fae\u5c0f\u8840\u7ba1\u75c7<\/li>\n\n\n\n<li>\u9aa8\u9ac4\u75be\u60a3<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u5c0f\u677f\u95a2\u9023\u6297\u4f53\u306e\u967d\u6027\u6240\u898b\u306f\u3001\u81e8\u5e8a\u7d4c\u904e\u3084\u4ed6\u306e\u691c\u67fb\u7d50\u679c\u3068\u5408\u308f\u305b\u3066\u89e3\u91c8\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u306b\u5408\u4f75\u3059\u308b\u771f\u306e\u514d\u75ab\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-1973\/\">SLE\u306b\u4f34\u3046\u96e3\u6cbb\u6027\u514d\u75ab\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u306e\u6cbb\u7642<\/a>\u3082\u53c2\u8003\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"480\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-76-480x600.png\" alt=\"SLE\u60a3\u8005\u306e\u8840\u5c0f\u677f\u6e1b\u5c11\u306b\u3064\u3044\u3066\u3001ITP\u3001\u51fa\u8840\u306b\u4f34\u3046\u6d88\u8cbb\u3001\u813e\u5185\u8caf\u7559\u3092\u533a\u5225\u3057\u3001\u975e\u7279\u7570\u7684\u8840\u5c0f\u677f\u6297\u4f53\u691c\u67fb\u306e\u507d\u967d\u6027\u3092\u793a\u3059\u6a21\u5f0f\u56f3\" class=\"wp-image-10077\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-76-480x600.png 480w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-76-240x300.png 240w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-76-767x959.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-76.png 800w\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac<\/strong>\uff1aSLE\u60a3\u8005\u306b\u304a\u3051\u308b\u8840\u5c0f\u677f\u6e1b\u5c11\u306e\u4e3b\u306a\u6a5f\u5e8f\u3068\u6297\u4f53\u691c\u67fb\u306e\u89e3\u91c8\u3002\u672c\u75c7\u4f8b\u3067\u306f\u8840\u5c0f\u677f\u95a2\u9023IgM\u6297\u4f53\u304c\u5f37\u967d\u6027\u3067\u3042\u3063\u305f\u3082\u306e\u306e\u3001\u8840\u5c0f\u677f\u7cd6\u86cb\u767d\u7279\u7570\u7684\u306a\u76f4\u63a5\u6297\u4f53\u691c\u67fb\u306f\u9670\u6027\u3067\u3042\u308a\u3001\u30ea\u30a6\u30de\u30c8\u30a4\u30c9\u56e0\u5b50IgM\u306b\u3088\u308b\u975e\u7279\u7570\u7684\u53cd\u5fdc\u304c\u8003\u3048\u3089\u308c\u305f\u3002\u8840\u5c0f\u677f\u6e1b\u5c11\u306e\u4e3b\u56e0\u306f\u6162\u6027\u51fa\u8840\u306b\u4f34\u3046\u6d88\u8cbb\u3068\u813e\u5185\u8caf\u7559\u306a\u3069\u306e\u8907\u5408\u7684\u8981\u56e0\u3068\u5224\u65ad\u3055\u308c\u305f\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c8\u7ae0\uff1a\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u306e\u5408\u4f75\uff5cCK\u8efd\u5ea6\u4e0a\u6607\u3067\u3082\u7b4b\u708e\u3092\u7591\u3046<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u8fd1\u4f4d\u7b4b\u512a\u4f4d\u306e\u7b4b\u529b\u4f4e\u4e0b\u304c\u6570\u304b\u6708\u306b\u308f\u305f\u308a\u9032\u884c\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u60a3\u8005\u306f\u6905\u5b50\u304b\u3089\u7acb\u3061\u4e0a\u304c\u308b\u3053\u3068\u3084\u968e\u6bb5\u6607\u964d\u304c\u56f0\u96e3\u3067\u3001\u4e0a\u80a2\u3092\u6319\u4e0a\u3059\u308b\u52d5\u4f5c\u3082\u969c\u5bb3\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8eab\u4f53\u8a3a\u5bdf\u3067\u306f\u8fd1\u4f4d\u7b4b\u7b4b\u529b\u4f4e\u4e0b\u3068\u7b4b\u840e\u7e2e\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CK\u306f268 U\/L\u3068\u8efd\u5ea6\u4e0a\u6607\u306b\u3068\u3069\u307e\u3063\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u7b4b\u96fb\u56f3\u3067\u306f\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u3092\u793a\u5506\u3059\u308b\u5909\u5316\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b4bMRI\u3068\u7b4b\u751f\u691c\u306f\u60a3\u8005\u304c\u5e0c\u671b\u3057\u306a\u304b\u3063\u305f\u305f\u3081\u5b9f\u65bd\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001\u672c\u75c7\u4f8b\u306e\u7b4b\u708e\u8a3a\u65ad\u306f\u3001\u81e8\u5e8a\u7d4c\u904e\u3001\u7b4b\u529b\u4f4e\u4e0b\u306e\u5206\u5e03\u3001\u7b4b\u96fb\u56f3\u6240\u898b\u306a\u3069\u3092\u7d71\u5408\u3057\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">SLE\u306b\u5408\u4f75\u3059\u308b\u708e\u75c7\u6027\u7b4b\u75be\u60a3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u60a3\u8005\u3067\u306f\u7b4b\u75db\u3084\u7b4b\u529b\u4f4e\u4e0b\u304c\u8a8d\u3081\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u660e\u78ba\u306a\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u3092\u5408\u4f75\u3059\u308b\u75c7\u4f8b\u3067\u306f\u3001\u7b4b\u75c7\u72b6\u3092\u72ec\u7acb\u3057\u305f\u81d3\u5668\u75c5\u5909\u3068\u3057\u3066\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u75c7\u72b6\u306f\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6905\u5b50\u304b\u3089\u7acb\u3061\u4e0a\u304c\u308a\u306b\u304f\u3044<\/li>\n\n\n\n<li>\u968e\u6bb5\u3092\u4e0a\u308b\u306e\u304c\u96e3\u3057\u3044<\/li>\n\n\n\n<li>\u9aea\u3092\u6d17\u3046\u52d5\u4f5c\u304c\u56f0\u96e3<\/li>\n\n\n\n<li>\u8155\u3092\u982d\u4e0a\u306b\u6319\u3052\u3089\u308c\u306a\u3044<\/li>\n\n\n\n<li>\u7b4b\u529b\u4f4e\u4e0b\u304c\u6570\u9031\u9593\u304b\u3089\u6570\u304b\u6708\u3067\u9032\u884c\u3059\u308b<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b4b\u529b\u4f4e\u4e0b\u304c\u660e\u3089\u304b\u306a\u5834\u5408\u306b\u306f\u3001CK\u304c\u8efd\u5ea6\u4e0a\u6607\u306b\u3068\u3069\u307e\u3063\u3066\u3044\u3066\u3082\u7b4b\u75be\u60a3\u3092\u5426\u5b9a\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">MCTD\u3068\u306e\u9451\u5225<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u306f\u6297RNP\u6297\u4f53\u967d\u6027\u3067\u3001\u30ec\u30a4\u30ce\u30fc\u73fe\u8c61\u3068\u7b4b\u708e\u3092\u4f34\u3063\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u305f\u3081MCTD\u3082\u9451\u5225\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6700\u7d42\u7684\u306b\u306f\u3001SLE\u3068\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u306e\u305d\u308c\u305e\u308c\u306e\u5206\u985e\u57fa\u6e96\u3092\u6e80\u305f\u3057\u305f\u3053\u3068\u304b\u3089\u3001SLE-IIM\u30aa\u30fc\u30d0\u30fc\u30e9\u30c3\u30d7\u75c7\u5019\u7fa4\u304c\u3088\u308a\u9069\u5207\u306a\u8a3a\u65ad\u3068\u5224\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8907\u6570\u306e\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306b\u5171\u901a\u3059\u308b\u7279\u5fb4\u3092\u6709\u3059\u308b\u5834\u5408\u306b\u306f\u3001\u81ea\u5df1\u6297\u4f53\u3060\u3051\u3067\u8a3a\u65ad\u540d\u3092\u6c7a\u3081\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u5b9f\u969b\u306e\u81d3\u5668\u75c5\u5909\u3068\u81e8\u5e8a\u50cf\u3092\u91cd\u8996\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c9\u7ae0\uff1a\u6cbb\u7642\u7d4c\u904e\uff5c\u5a66\u4eba\u79d1\u7684\u6b62\u8840\u3068\u514d\u75ab\u6291\u5236\u7642\u6cd5<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u751f\u547d\u3092\u8105\u304b\u3059\u5b50\u5bae\u51fa\u8840\u3078\u306e\u5bfe\u5fdc\u304c\u6700\u512a\u5148\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u51fa\u8840\u306b\u5bfe\u3059\u308b\u6cbb\u7642<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u3001\u8840\u5c0f\u677f\u8f38\u8840\u3001\u8d64\u8840\u7403\u8f38\u8840\u306a\u3069\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u304c\u3001\u5927\u91cf\u51fa\u8840\u306f\u6301\u7d9a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5165\u96623\u65e5\u76ee\u306b\u8179\u8154\u93e1\u4e0b\u5b50\u5bae\u5168\u6458\u8853\u304a\u3088\u3073\u4e21\u5074\u5375\u7ba1\u5207\u9664\u8853\u304c\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u624b\u8853\u6a19\u672c\u3067\u306f\u8907\u6570\u306e\u5b50\u5bae\u5e73\u6ed1\u7b4b\u816b\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u624b\u8853\u5f8c\u3001\u8ca7\u8840\u306f\u5b89\u5b9a\u3057\u3001\u8ffd\u52a0\u306e\u8d64\u8840\u7403\u8f38\u8840\u306f\u4e0d\u8981\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 SLE\u306b\u5bfe\u3059\u308b\u6cbb\u7642<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u3068\u8a3a\u65ad\u3055\u308c\u305f\u6bb5\u968e\u3067\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30af\u30ed\u30ed\u30ad\u30f3\u304c\u958b\u59cb\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d2\u30c9\u30ed\u30ad\u30b7\u30af\u30ed\u30ed\u30ad\u30f3\u306f\u3001SLE\u306e\u518d\u71c3\u6291\u5236\u3001\u81d3\u5668\u969c\u5bb3\u306e\u84c4\u7a4d\u6291\u5236\u3001\u751f\u5b58\u7387\u6539\u5584\u306a\u3069\u3092\u76ee\u7684\u3068\u3057\u305f\u57fa\u672c\u7684\u306a\u6cbb\u7642\u85ac\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u708e\u75c7\u6027\u7b4b\u75be\u60a3\u306b\u5bfe\u3059\u308b\u6cbb\u7642<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u901a\u5e38\u3001\u6d3b\u52d5\u6027\u306e\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u3067\u306f\u526f\u814e\u76ae\u8cea\u30b9\u30c6\u30ed\u30a4\u30c9\u304c\u6cbb\u7642\u9078\u629e\u80a2\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u672c\u75c7\u4f8b\u3067\u306f\u5e83\u7bc4\u56f2\u306e\u30ea\u30f3\u30d1\u7bc0\u816b\u8139\u3068\u813e\u816b\u306e\u539f\u56e0\u691c\u7d22\u304c\u7d99\u7d9a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u5f53\u521d\u306f\u30b9\u30c6\u30ed\u30a4\u30c9\u6295\u4e0e\u3092\u63a7\u3048\u3001\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u9759\u6ce8\u7642\u6cd5\uff08IVIG\uff09\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6cbb\u7642\u5f8c\u3001\u8fd1\u4f4d\u7b4b\u7b4b\u529b\u306f\u901f\u3084\u304b\u306b\u6539\u5584\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306b\u5bfe\u3059\u308b\u6cbb\u7642<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u814e\u751f\u691c\u3067Class V\u512a\u4f4d\u3001Class III\u6210\u5206\u3092\u4f34\u3046\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u304c\u78ba\u8a8d\u3055\u308c\u305f\u305f\u3081\u3001\u4ee5\u4e0b\u306e\u6cbb\u7642\u304c\u9078\u629e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u526f\u814e\u76ae\u8cea\u30b9\u30c6\u30ed\u30a4\u30c9<\/li>\n\n\n\n<li>\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u30e2\u30d5\u30a7\u30c1\u30eb\uff08MMF\uff09<\/li>\n\n\n\n<li>\u30d9\u30ea\u30e0\u30de\u30d6<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d9\u30ea\u30e0\u30de\u30d6\u306f\u9000\u96622\u304b\u6708\u5f8c\u306b\u8ffd\u52a0\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pneumocystis jirovecii\u80ba\u708e\u4e88\u9632\u3068\u3057\u3066ST\u5408\u5264\u3082\u958b\u59cb\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u306a\u304a\u3001\u3053\u308c\u306f\u672c\u75c7\u4f8b\u306b\u304a\u3051\u308b\u6cbb\u7642\u9078\u629e\u3067\u3042\u308a\u3001\u3059\u3079\u3066\u306e\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u60a3\u8005\u306b\u540c\u4e00\u306e3\u5264\u4f75\u7528\u304c\u5fc5\u8981\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d44\u7e54\u578b\u3001\u86cb\u767d\u5c3f\u3001\u814e\u6a5f\u80fd\u3001\u814e\u5916\u75c5\u5909\u3001\u611f\u67d3\u75c7\u30ea\u30b9\u30af\u306a\u3069\u306b\u5fdc\u3058\u305f\u6cbb\u7642\u306e\u500b\u5225\u5316\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d9\u30ea\u30e0\u30de\u30d6\u306e\u814e\u75c5\u5909\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u52b9\u679c\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/lupus-nephritis-belimumab-deep-renal-response\/\" target=\"_blank\" rel=\"noopener\">\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u3068\u30d9\u30ea\u30e0\u30de\u30d6\uff5c\u6df1\u3044\u814e\u594f\u52b9\u306e\u6700\u65b0\u7814\u7a76<\/a>\u3067\u3082\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c10\u7ae0\uff1a\u6cbb\u7642\u5f8c\u306e\u7d4c\u904e\u3068\u4e88\u5f8c<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u6cbb\u7642\u5f8c\u3001\u60a3\u8005\u306e\u5168\u8eab\u72b6\u614b\u306f\u8457\u660e\u306b\u6539\u5584\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6700\u7d42\u7684\u306b\u3001\u4ee5\u4e0b\u306e\u6539\u5584\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>CK\u5024\u306e\u6b63\u5e38\u5316<\/li>\n\n\n\n<li>\u8fd1\u4f4d\u7b4b\u7b4b\u529b\u306e\u5b8c\u5168\u306a\u56de\u5fa9<\/li>\n\n\n\n<li>\u86cb\u767d\u5c3f\u306e\u6d88\u5931<\/li>\n\n\n\n<li>\u814e\u6a5f\u80fd\u306e\u7dad\u6301<\/li>\n\n\n\n<li>\u8131\u6bdb\u306e\u6539\u5584<\/li>\n\n\n\n<li>\u5168\u8eab\u5026\u6020\u611f\u306e\u6539\u5584<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u5a66\u4eba\u79d1\u7684\u51fa\u8840\u3078\u306e\u9069\u5207\u306a\u51e6\u7f6e\u3068\u3001SLE\u30fb\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u306b\u5bfe\u3059\u308b\u514d\u75ab\u8abf\u6574\u7642\u6cd5\u306e\u4e21\u65b9\u304c\u91cd\u8981\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u306f1\u75c7\u4f8b\u306e\u6cbb\u7642\u7d4c\u904e\u3067\u3042\u308a\u3001\u540c\u69d8\u306e\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u5168\u4f53\u306b\u540c\u3058\u8ee2\u5e30\u304c\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u3092\u8a3c\u660e\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u7b2c11\u7ae0\uff1a\u672c\u75c7\u4f8b\u304b\u3089\u5b66\u30765\u3064\u306e\u81e8\u5e8a\u7684\u30dd\u30a4\u30f3\u30c8<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u76ee\u7acb\u3064\u4e3b\u8a34\u3060\u3051\u3067\u8a3a\u65ad\u3092\u5b8c\u7d50\u3055\u305b\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u91cd\u75c7\u306e\u5b50\u5bae\u51fa\u8840\u3068\u9244\u6b20\u4e4f\u6027\u8ca7\u8840\u304c\u5b58\u5728\u3057\u3066\u3082\u3001\u5168\u8eab\u6027\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u304c\u4f75\u5b58\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5225\u306e\u75c5\u614b\u3092\u793a\u5506\u3059\u308b\u6240\u898b\u304c\u3042\u308c\u3070\u3001\u8a3a\u65ad\u3092\u518d\u691c\u8a0e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 CK\u304c\u8efd\u5ea6\u4e0a\u6607\u3067\u3082\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u306f\u5426\u5b9a\u3067\u304d\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b4b\u708e\u306e\u8a55\u4fa1\u3067\u306f\u3001CK\u5024\u3060\u3051\u3067\u306a\u304f\u3001\u7b4b\u529b\u4f4e\u4e0b\u306e\u5206\u5e03\u3001\u9032\u884c\u901f\u5ea6\u3001\u7b4b\u96fb\u56f3\u3001MRI\u3001\u7b4b\u751f\u691c\u306a\u3069\u306e\u6240\u898b\u3092\u7dcf\u5408\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u814e\u6a5f\u80fd\u304c\u6b63\u5e38\u3067\u3082\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306f\u5b58\u5728\u3059\u308b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u304c\u6b63\u5e38\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u814e\u751f\u691c\u3067Class V\u512a\u4f4d\u3001Class III\u6210\u5206\u3092\u4f34\u3046\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u60a3\u8005\u3067\u306f\u5c3f\u86cb\u767d\u3001\u5c3f\u6c88\u6e23\u3001\u814e\u6a5f\u80fd\u3092\u7d99\u7d9a\u3057\u3066\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u8840\u5c0f\u677f\u95a2\u9023\u6297\u4f53\u967d\u6027\u306fITP\u306e\u78ba\u5b9a\u8a3a\u65ad\u3067\u306f\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u5c0f\u677f\u95a2\u9023\u6297\u4f53\u691c\u67fb\u306f\u3001\u6e2c\u5b9a\u6cd5\u3084\u975e\u7279\u7570\u7684\u306a\u6297\u4f53\u7d50\u5408\u306b\u3088\u3063\u3066\u507d\u967d\u6027\u3092\u751f\u3058\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u5c0f\u677f\u6e1b\u5c11\u306e\u539f\u56e0\u3092\u81e8\u5e8a\u7d4c\u904e\u3068\u3068\u3082\u306b\u518d\u8a55\u4fa1\u3059\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2464 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class=\"wp-block-paragraph\">\u65e5\u5e38\u8a3a\u7642\u3067\u306f\u3001\u8ca7\u8840\u3001\u8131\u6bdb\u3001\u5026\u6020\u611f\u3001\u7b4b\u529b\u4f4e\u4e0b\u306a\u3069\u304c\u3001\u305d\u308c\u305e\u308c\u5225\u306e\u8a3a\u7642\u79d1\u3067\u8a55\u4fa1\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u75c7\u72b6\u304c\u8907\u6570\u91cd\u306a\u308b\u5834\u5408\u306b\u306f\u3001\u5168\u8eab\u6027\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3092\u691c\u8a0e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u8ca7\u8840\u306b\u52a0\u3048\u3066\u767d\u8840\u7403\u3084\u8840\u5c0f\u677f\u3082\u6e1b\u5c11\u3057\u3066\u3044\u308b<\/li>\n\n\n\n<li>\u8131\u6bdb\u3068\u30ec\u30a4\u30ce\u30fc\u73fe\u8c61\u3092\u4f34\u3046<\/li>\n\n\n\n<li>\u7b4b\u529b\u4f4e\u4e0b\u304c\u6570\u304b\u6708\u306b\u308f\u305f\u308a\u9032\u884c\u3057\u3066\u3044\u308b<\/li>\n\n\n\n<li>\u539f\u56e0\u4e0d\u660e\u306e\u30ea\u30f3\u30d1\u7bc0\u816b\u8139\u3084\u813e\u816b\u304c\u3042\u308b<\/li>\n\n\n\n<li>\u5c3f\u86cb\u767d\u3084\u8840\u5c3f\u304c\u6301\u7d9a\u3057\u3066\u3044\u308b<\/li>\n\n\n\n<li>ESR\u304c\u9ad8\u5024\u3067\u3001\u307b\u304b\u306b\u3082\u81a0\u539f\u75c5\u3092\u7591\u3046\u6240\u898b\u304c\u3042\u308b<\/li>\n<\/ul>\n\n\n\n<p 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class=\"wp-block-paragraph\">NEJM\u3067\u5831\u544a\u3055\u308c\u305f\u672c\u75c7\u4f8b\u306f\u3001\u91cd\u75c7\u306e\u4e0d\u6b63\u6027\u5668\u51fa\u8840\u3068\u8ca7\u8840\u3092\u5951\u6a5f\u3068\u3057\u3066\u3001SLE\u3068\u7279\u767a\u6027\u708e\u75c7\u6027\u7b4b\u75be\u60a3\u306e\u30aa\u30fc\u30d0\u30fc\u30e9\u30c3\u30d7\u75c7\u5019\u7fa4\u304c\u8a3a\u65ad\u3055\u308c\u305f50\u6b73\u5973\u6027\u306e\u75c7\u4f8b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5b50\u5bae\u7b4b\u816b\u306b\u3088\u308b\u51fa\u8840\u306f\u78ba\u304b\u306b\u5b58\u5728\u3057\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u9032\u884c\u3059\u308b\u7b4b\u529b\u4f4e\u4e0b\u3001\u8131\u6bdb\u3001\u30ec\u30a4\u30ce\u30fc\u73fe\u8c61\u3001\u8840\u5c0f\u677f\u6e1b\u5c11\u3001\u86cb\u767d\u5c3f\u306a\u3069\u306e\u80cc\u666f\u306b\u306f\u5168\u8eab\u6027\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u304c\u5b58\u5728\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u8907\u6570\u306e\u75c7\u72b6\u304c\u3042\u308a\u3001\u3069\u306e\u8a3a\u7642\u79d1\u3092\u53d7\u8a3a\u3059\u308c\u3070\u3088\u3044\u304b\u5206\u304b\u3089\u306a\u3044\u5834\u5408\u306b\u3082\u3001\u75c7\u72b6\u3084\u691c\u67fb\u7d50\u679c\u3092\u6574\u7406\u3057\u306a\u304c\u3089\u8a3a\u65ad\u3092\u9032\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5c02\u9580\u7684\u306a\u691c\u67fb\u3084\u5165\u9662\u6cbb\u7642\u304c\u5fc5\u8981\u306a\u5834\u5408\u306b\u306f\u3001\u9069\u5207\u306a\u533b\u7642\u6a5f\u95a2\u3068\u9023\u643a\u3057\u3066\u8a3a\u7642\u3092\u884c\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u67cf\u5e02\u30fb\u6211\u5b6b\u5b50\u5e02\u3092\u4e2d\u5fc3\u306b\u3001\u6d41\u5c71\u5e02\u30fb\u677e\u6238\u5e02\u30fb\u5370\u897f\u5e02\u30fb\u767d\u4e95\u5e02\u306a\u3069\u304b\u3089\u306e\u3054\u76f8\u8ac7\u306b\u3082\u5bfe\u5fdc\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/rheumatology-allergy.html\" target=\"_blank\" rel=\"noopener\">\u30ea\u30a6\u30de\u30c1\u30fb\u81a0\u539f\u75c5\u30fb\u30a2\u30ec\u30eb\u30ae\u30fc\u5185\u79d1\u306e\u8a3a\u7642\u6848\u5185<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u95a2\u9023\u8a18\u4e8b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1\uff0e<\/strong><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-1987\/\" target=\"_blank\" rel=\"noopener\"><strong>\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\uff5c\u81e8\u5e8a\u50cf\u3068\u8a3a\u65ad\u30fb\u6cbb\u7642\u306e\u7dcf\u5408\u30ec\u30d3\u30e5\u30fc<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u306e\u4ee3\u8868\u7684\u306a\u75c7\u72b6\u3001\u81ea\u5df1\u6297\u4f53\u3001\u8a3a\u65ad\u57fa\u6e96\u3001\u6cbb\u7642\u306b\u3064\u3044\u3066\u7dcf\u5408\u7684\u306b\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002\u672c\u75c7\u4f8b\u3067\u8a8d\u3081\u3089\u308c\u305f\u8131\u6bdb\u3001\u8840\u7403\u6e1b\u5c11\u3001\u814e\u969c\u5bb3\u306a\u3069\u306e\u5168\u8eab\u75c7\u72b6\u3092\u7406\u89e3\u3059\u308b\u3046\u3048\u3067\u53c2\u8003\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2\uff0e<\/strong><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-8775\/\" target=\"_blank\" rel=\"noopener\"><strong>SLE\u30fb\u30eb\u30fc\u30d7\u30b9\u814e\u708e\uff5c\u6700\u65b0\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068\u6cbb\u7642\u6226\u7565<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306e\u75c5\u578b\u5206\u985e\u3001\u814e\u751f\u691c\u306e\u91cd\u8981\u6027\u3001\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u88fd\u5264\u3084\u30d9\u30ea\u30e0\u30de\u30d6\u3092\u542b\u3080\u6cbb\u7642\u6226\u7565\u3092\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002\u672c\u75c7\u4f8b\u3067\u8a3a\u65ad\u3055\u308c\u305fClass V\u512a\u4f4d\u306e\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306b\u3064\u3044\u3066\u3001\u6cbb\u7642\u9078\u629e\u3092\u3055\u3089\u306b\u8a73\u3057\u304f\u5b66\u3079\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>3\uff0e<\/strong><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-1973\/\" target=\"_blank\" rel=\"noopener\"><strong>SLE\u306b\u4f34\u3046\u96e3\u6cbb\u6027\u514d\u75ab\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u306e\u6cbb\u7642<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SLE\u306b\u5408\u4f75\u3059\u308b\u514d\u75ab\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\uff08ITP\uff09\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002\u672c\u75c7\u4f8b\u3067\u306f\u8840\u5c0f\u677f\u6e1b\u5c11\u306e\u4e3b\u56e0\u306f\u514d\u75ab\u6027\u7834\u58ca\u3067\u306f\u306a\u3044\u3068\u5224\u65ad\u3055\u308c\u307e\u3057\u305f\u3002SLE\u306b\u304a\u3051\u308b\u8840\u5c0f\u677f\u6e1b\u5c11\u306e\u9451\u5225\u3068\u6cbb\u7642\u65b9\u91dd\u3092\u8003\u3048\u308b\u3046\u3048\u3067\u3001\u5bfe\u6bd4\u3057\u3066\u8aad\u3080\u4fa1\u5024\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\">Ziperstein JC, Barnawi RA, Al-Samkari H, Bolster MB, Heusinkveld LE. Case 14-2026: A 50-Year-Old Woman with Vaginal Bleeding and Anemia. N Engl J Med. 2026;394:1940\u20131951.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">DOI: 10.1056\/NEJMcpc2517864<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u539f\u8457\uff1a<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMcpc2517864\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMcpc2517864<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Aringer M, et al. 2019 European League Against Rheumatism\/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus. Arthritis Rheumatol. 2019;71:1400\u20131412.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Lundberg IE, et al. 2017 European League Against Rheumatism\/American College of Rheumatology Classification Criteria for Adult and Juvenile Idiopathic Inflammatory Myopathies and Their Major Subgroups. Ann Rheum Dis. 2017;76:1955\u20131964.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Sammaritano LR, et al. 2024 American College of Rheumatology (ACR) Guideline for the Screening, Treatment, and Management of Lupus Nephritis. Arthritis Rheumatol. 2025;77:1115\u20131135.<\/p>\n<\/div><\/div>\n<\/blockquote>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\">\u203b\u672c\u8a18\u4e8b\u306fNEJM\u306b\u63b2\u8f09\u3055\u308c\u305f\u75c7\u4f8b\u5831\u544a\u3092\u3082\u3068\u306b\u3001\u81e8\u5e8a\u7684\u306a\u5b66\u3073\u3092\u6574\u7406\u3057\u305f\u3082\u306e\u3067\u3059\u3002\u8a3a\u65ad\u3084\u6cbb\u7642\u306f\u500b\u3005\u306e\u60a3\u8005\u3055\u3093\u306e\u72b6\u614b\u306b\u5fdc\u3058\u3066\u5224\u65ad\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u91cd\u8981\u8981\u70b9 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