{"id":1403,"date":"2026-02-06T19:14:30","date_gmt":"2026-02-06T10:14:30","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=1403"},"modified":"2026-03-30T14:46:04","modified_gmt":"2026-03-30T05:46:04","slug":"post-1403","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-1403\/","title":{"rendered":"VEXAS\u75c7\u5019\u7fa4\u306b\u3064\u3044\u3066\u306e\u6700\u65b0\u898b\u89e3"},"content":{"rendered":"\n<p>2020\u5e74\u306b\u767a\u898b\u3055\u308c\u305f<strong>VEXAS\u75c7\u5019\u7fa4<\/strong>\u3068\u3044\u3046\u3001\u4e3b\u306b50\u6b73\u4ee5\u4e0a\u306e\u7537\u6027\u306b\u767a\u75c7\u3059\u308b<strong>\u5358\u4e00\u907a\u4f1d\u5b50\u6027\u306e\u81ea\u5df1\u708e\u75c7\u6027\u75be\u60a3<\/strong>\u306b\u3064\u3044\u3066\u5305\u62ec\u7684\u306b\u89e3\u8aac\u3057\u305f\u30ec\u30d3\u30e5\u30fc\u304cLancet\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u306e\u3067\u89e3\u8aac\u3057\u307e\u3059\u3002\u672c\u75be\u60a3\u306f\u3001\u8840\u6db2\u7d30\u80de\u306b\u304a\u3051\u308b<strong>UBA1\u907a\u4f1d\u5b50\u306e\u5f8c\u5929\u7684\uff08\u4f53\u7d30\u80de\uff09\u5909\u7570<\/strong>\u3092\u539f\u56e0\u3068\u3057\u3001\u65e2\u5b58\u306e\u6cbb\u7642\u306b\u62b5\u6297\u3059\u308b\u5168\u8eab\u6027\u306e\u708e\u75c7\u3068<strong>\u9032\u884c\u6027\u306e\u9aa8\u9ac4\u4e0d\u5168<\/strong>\u3092\u7279\u5fb4\u3068\u3059\u308b\u3001\u547d\u306b\u95a2\u308f\u308b\u91cd\u7be4\u306a\u75c5\u614b\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3000<\/p>\n\n\n\n<p>\u3053\u306e\u75c5\u6c17\u304c\u518d\u767a\u6027\u591a\u767a\u8edf\u9aa8\u708e\u3084\u9aa8\u9ac4\u7570\u5f62\u6210\u75c7\u5019\u7fa4\u3068\u3044\u3063\u305f<strong>\u65e2\u5b58\u306e\u8907\u6570\u306e\u75be\u60a3\u3068\u75c7\u72b6\u304c\u9177\u4f3c\u3057\u3066\u3044\u308b<\/strong>\u70b9\u306b\u7740\u76ee\u3057\u3001\u6b63\u78ba\u306a\u8a3a\u65ad\u306b\u306f<strong>UBA1\u5909\u7570\u306e\u907a\u4f1d\u5b50\u691c\u67fb<\/strong>\u304c\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3053\u3068\u3092\u5f37\u8abf\u3057\u3066\u3044\u307e\u3059\u3002\u6cbb\u7642\u9762\u3067\u306f\u3001\u708e\u75c7\u306e\u6291\u5236\u306b<strong>\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9<\/strong>\u304c\u6709\u52b9\u3067\u3042\u308b\u4e00\u65b9\u3001\u526f\u4f5c\u7528\u306e\u61f8\u5ff5\u304b\u3089<strong>JAK\u963b\u5bb3\u85ac<\/strong>\u3084<strong>IL-6\u963b\u5bb3\u85ac<\/strong>\u306a\u3069\u306e\u4f75\u7528\u304c\u691c\u8a0e\u3055\u308c\u3001\u3055\u3089\u306b\u6839\u6cbb\u7684\u6cbb\u7642\u3068\u3057\u3066<strong>\u30a2\u30b6\u30b7\u30c1\u30b8\u30f3<\/strong>\u3092\u7528\u3044\u305f\u5316\u5b66\u7642\u6cd5\u3084<strong>\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d<\/strong>\u306e\u6709\u52b9\u6027\u304c\u63d0\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>VEXAS\u75c7\u5019\u7fa4\u306e<strong>\u5206\u5b50\u751f\u7269\u5b66\u7684\u306a\u30e1\u30ab\u30cb\u30ba\u30e0<\/strong>\u304b\u3089<strong>\u81e8\u5e8a\u7684\u306a\u591a\u69d8\u6027<\/strong>\u3001\u305d\u3057\u3066<strong>\u6700\u65b0\u306e\u6cbb\u7642\u6226\u7565<\/strong>\u307e\u3067\u3092\u4f53\u7cfb\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u8840\u6db2\u5b66\u3068\u81a0\u539f\u75c5\u5b66\u306e\u5883\u754c\u9818\u57df\u306b\u304a\u3051\u308b\u65b0\u305f\u306a\u75be\u60a3\u6982\u5ff5\u3092\u78ba\u7acb\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<figure 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