{"id":3446,"date":"2026-04-14T19:46:36","date_gmt":"2026-04-14T10:46:36","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=3446"},"modified":"2026-04-14T19:46:36","modified_gmt":"2026-04-14T10:46:36","slug":"post-3446","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-3446\/","title":{"rendered":"\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306e\u5bdb\u89e3\u7dad\u6301\u3068\u85ac\u306e\u6e1b\u3089\u3057\u65b9\uff1a\u751f\u7269\u5b66\u7684\u88fd\u5264\u30fbJAK\u963b\u5bb3\u85ac\u306e\u7279\u6027\u306b\u5fdc\u3058\u305f\u9069\u5207\u306a\u6e1b\u91cf\u6226\u7565"},"content":{"rendered":"\n<p>\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\uff08RA\uff09\u6cbb\u7642\u306e\u6700\u7d42\u76ee\u6a19\u306f\u300c\u81e8\u5e8a\u7684\u5bdb\u89e3\u300d\u3092\u9054\u6210\u3057\u3001\u9577\u671f\u7684\u306b\u7dad\u6301\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u6700\u65b0\u306e\u751f\u7269\u5b66\u7684\u88fd\u5264\u3084JAK\u963b\u5bb3\u85ac\u306e\u767b\u5834\u306b\u3088\u308a\u3001\u591a\u304f\u306e\u60a3\u8005\u69d8\u304c\u5bdb\u89e3\u306b\u81f3\u308b\u3053\u3068\u304c\u53ef\u80fd\u3068\u306a\u308a\u307e\u3057\u305f\u304c\u3001\u305d\u306e\u5f8c\u306e\u5927\u304d\u306a\u8ab2\u984c\u306f\u300c\u3069\u306e\u3088\u3046\u306b\u85ac\u3092\u5b89\u5168\u306b\u6e1b\u91cf\u3057\u3066\u3044\u304f\u304b\u300d\u3068\u3044\u3046\u70b9\u3067\u3059\u3002<\/p>\n\n\n\n<p>TNF\u963b\u5bb3\u85ac\uff08\u30a8\u30bf\u30cd\u30eb\u30bb\u30d7\u30c8\u306a\u3069\uff09\u3092\u7528\u3044\u30663\u301c12\u30f6\u6708\u9593\u5b89\u5b9a\u3057\u3066\u5bdb\u89e3\u3092\u7dad\u6301\u3067\u304d\u305f\u5834\u5408\u3001\u6295\u4e0e\u91cf\u3092\u6e1b\u3089\u3057\u305f\u308a\u3001\u6295\u4e0e\u9593\u9694\u3092\u5ef6\u9577\u3057\u305f\u308a\u3057\u3066\u3082\u3001\u85ac\u3092\u305d\u306e\u307e\u307e\u7d99\u7d9a\u3057\u305f\u5834\u5408\u3068\u6bd4\u8f03\u3057\u3066\u3001\u5bdb\u89e3\u7dad\u6301\u7387\u3084\u95a2\u7bc0\u7834\u58ca\u306e\u9032\u884c\u6291\u5236\u3001\u8eab\u4f53\u6a5f\u80fd\u306e\u7dad\u6301\uff08HAQ\uff09\u306b\u304a\u3044\u3066\u6709\u610f\u306a\u5dee\u304c\u306a\u3044\u3053\u3068\u304c\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u3088\u308a\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u85ac\u3092\u5b8c\u5168\u306b\u300c\u4e2d\u6b62\u300d\u3057\u3066\u3057\u307e\u3046\u3068\u518d\u71c3\u7387\u304c\u5927\u5e45\u306b\u9ad8\u307e\u308a\u3001\u95a2\u7bc0\u7834\u58ca\u304c\u9032\u884c\u3059\u308b\u30ea\u30b9\u30af\u304c\u6709\u610f\u306b\u5897\u52a0\u3059\u308b\u305f\u3081\u3001<strong>\u4e2d\u6b62\u3088\u308a\u3082\u7de9\u3084\u304b\u306a\u6e1b\u91cf\u3084\u9593\u9694\u5ef6\u9577<\/strong>\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30e1\u30bd\u30c8\u30ec\u30ad\u30bb\u30fc\u30c8\uff08MTX\uff09\u306a\u3069\u306e\u5f93\u6765\u578b\u6297\u30ea\u30a6\u30de\u30c1\u85ac\uff08csDMARDs\uff09\u3068\u751f\u7269\u88fd\u5264\u30fbJAK\u963b\u5bb3\u85ac\u3092\u4f75\u7528\u3057\u3066\u3044\u308b\u5834\u5408\u3001\u3069\u3061\u3089\u304b\u3089\u6e1b\u3089\u3059\u3079\u304d\u304b\u306b\u3064\u3044\u3066\u306f\u3001<strong>\u307e\u305aMTX\u306a\u3069\u306e\u5f93\u6765\u85ac\u304b\u3089\u6e1b\u91cf\u3057\u3066\u3044\u304f\u65b9\u91dd<\/strong>\u304c\u4e00\u822c\u7684\u3067\u3059\u3002\u3053\u308c\u306f\u3001\u751f\u7269\u5b66\u7684\u88fd\u5264\u3092\u5358\u5264\u3067\u7d99\u7d9a\u3057\u3066\u3082\u3001\u4f75\u7528\u6642\u3068\u540c\u7b49\u306e\u5bdb\u89e3\u7dad\u6301\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b\u3068\u3044\u3046\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30a2\u30af\u30c6\u30e0\u30e9\uff08IL-6\u963b\u5bb3\u85ac\uff09\u306b\u3064\u3044\u3066\u306f\u3001\u5b8c\u5168\u306b\u3084\u3081\u3066\u3057\u307e\u3046\u3068\u5bdb\u89e3\u3092\u7dad\u6301\u3067\u304d\u308b\u5272\u5408\u306f\u4f4e\u304f\u306a\u308a\u307e\u3059\u304c\u3001\u6295\u4e0e\u9593\u9694\u30924\u9031\u304b\u30896\u9031\u3078\u5ef6\u3070\u3059\u3053\u3068\u3067\u3001\u7d0487%\u3068\u3044\u3046\u9ad8\u3044\u5272\u5408\u3067\u5bdb\u89e3\u3092\u7dad\u6301\u3057\u3001\u95a2\u7bc0\u7834\u58ca\u306e\u9032\u884c\u3082\u9632\u3052\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<strong>\u6e1b\u91cf\u3088\u308a\u3082\u9593\u9694\u3092\u4f38\u3070\u3059\u6226\u8853<\/strong>\u304c\u3088\u3044\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u85ac\u306e\u6e1b\u91cf\u306f\u3001\u518d\u71c3\u306e\u5146\u5019\u3092\u898b\u9003\u3055\u306a\u3044\u3088\u3046\u3001\u5c02\u9580\u533b\u306b\u3088\u308b\u614e\u91cd\u306a\u7ba1\u7406\u306e\u3082\u3068\u3067\u9032\u3081\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"430\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-1.jpg\" alt=\"\" class=\"wp-image-3447\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-1.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-1-400x215.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"440\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-6.jpg\" alt=\"\" class=\"wp-image-3452\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-6.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-6-400x220.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"442\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-7.jpg\" alt=\"\" class=\"wp-image-3453\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-7.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-7-400x221.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"443\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-8.jpg\" alt=\"\" class=\"wp-image-3454\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-8.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-8-400x222.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"442\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-9.jpg\" alt=\"\" class=\"wp-image-3455\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-9.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-9-400x221.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"434\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-10.jpg\" alt=\"\" class=\"wp-image-3456\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-10.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-10-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-11.jpg\" alt=\"\" class=\"wp-image-3457\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-11.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-11-400x218.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"426\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-12.jpg\" alt=\"\" class=\"wp-image-3458\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-12.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-12-400x213.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-13.jpg\" alt=\"\" class=\"wp-image-3459\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-13.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-13-400x218.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"424\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-14.jpg\" alt=\"\" class=\"wp-image-3460\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-14.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-14-400x212.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-15.jpg\" alt=\"\" class=\"wp-image-3461\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-15.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-15-400x218.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"458\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-16.jpg\" alt=\"\" class=\"wp-image-3462\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-16.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-20-16-400x229.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p>\u6700\u5f8c\u306b\u3001\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u3001\u75c7\u72b6\u306e\u80cc\u666f\u306b\u3042\u308b\u300c\u4f53\u306e\u4ed5\u7d44\u307f\u300d\u307e\u3067\u4e01\u5be7\u306b\u8aac\u660e\u3057\u306a\u304c\u3089\u3001\u5185\u79d1\u30fb\u30ea\u30a6\u30de\u30c1\u30fb\u81a0\u539f\u75c5\u8a3a\u7642\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u300c\u306a\u305c\u3053\u306e\u75c7\u72b6\u304c\u8d77\u304d\u308b\u306e\u304b\u300d\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3092\u5927\u5207\u306b\u3057\u3066\u3044\u307e\u3059\u3002 \u67cf\u5e02\u30fb\u6211\u5b6b\u5b50\u5e02\u5468\u8fba\u3067\u3001\u95a2\u7bc0\u306e\u75db\u307f\u3084\u539f\u56e0\u306e\u5206\u304b\u3089\u306a\u3044\u4f53\u8abf\u4e0d\u826f\u306b\u304a\u60a9\u307f\u306e\u65b9\u306f\u3001\u3069\u3046\u305e\u304a\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\uff08RA\uff09\u6cbb\u7642\u306e\u6700\u7d42\u76ee\u6a19\u306f\u300c\u81e8\u5e8a\u7684\u5bdb\u89e3\u300d\u3092\u9054\u6210\u3057\u3001\u9577\u671f\u7684\u306b\u7dad\u6301\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u6700\u65b0\u306e\u751f\u7269\u5b66\u7684\u88fd\u5264\u3084JAK\u963b\u5bb3\u85ac\u306e\u767b\u5834\u306b\u3088\u308a\u3001\u591a\u304f\u306e\u60a3\u8005\u69d8\u304c\u5bdb\u89e3\u306b\u81f3\u308b\u3053\u3068&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[40,9],"class_list":["post-3446","post","type-post","status-publish","format-standard","hentry","category-40","category-9"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3446","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/comments?post=3446"}],"version-history":[{"count":1,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3446\/revisions"}],"predecessor-version":[{"id":3463,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3446\/revisions\/3463"}],"wp:attachment":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/media?parent=3446"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/categories?post=3446"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}