{"id":3639,"date":"2026-04-18T21:37:47","date_gmt":"2026-04-18T12:37:47","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=3639"},"modified":"2026-04-18T21:37:47","modified_gmt":"2026-04-18T12:37:47","slug":"post-3639","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-3639\/","title":{"rendered":"\u30dc\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\u306e\u814e\u79fb\u690d\u306b\u304a\u3051\u308b\u62d2\u7d76\u53cd\u5fdc\u6291\u5236\u80fd\u3068\u5b89\u5168\u6027\u306e\u691c\u8a3c\uff1aPROMISE\u8a66\u9a13\uff08\u7b2c2b\u76f8\uff09\u306b\u57fa\u3065\u304f\u89e3\u6790"},"content":{"rendered":"\n<p>\u814e\u79fb\u690d\u5f8c\u306e\u514d\u75ab\u6291\u5236\u7642\u6cd5\u306b\u304a\u3044\u3066\u3001\u30ab\u30eb\u30b7\u30cb\u30e5\u30fc\u30ea\u30f3\u963b\u5bb3\u85ac\uff08CNI\uff09\u306f\u4e2d\u5fc3\u7684\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\uff08TAC\uff09\u3084\u30b7\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\uff08CsA\uff09\u306f\u814e\u6bd2\u6027\u3084\u79fb\u690d\u5f8c\u65b0\u898f\u767a\u75c7\u7cd6\u5c3f\u75c5\uff08NODAT\uff09\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3068\u3044\u3063\u305f\u4ee3\u8b1d\u6027\u526f\u4f5c\u7528\u304c\u9577\u671f\u4e88\u5f8c\u306e\u963b\u5bb3\u56e0\u5b50\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30dc\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\uff08VCS\uff09\u306f\u3001CsA\u306e\u30a2\u30df\u30ce\u9178-1\u6b8b\u57fa\u306b\u5358\u4e00\u306e\u70ad\u7d20\u5206\u5b50\u3092\u4ed8\u52a0\u3057\u305f\u65b0\u898fCNI\u3067\u3042\u308a\u3001CN\u3078\u306e\u7d50\u5408\u80fd\u5411\u4e0a\u3068\u4ee3\u8b1d\u7523\u7269\u306e\u8fc5\u901f\u306a\u6392\u6cc4\u306b\u3088\u308a\u3001CsA\u4ee5\u4e0a\u306e\u9ad8\u529b\u4fa1\u3068\u5b89\u5b9a\u3057\u305f\u85ac\u7269\u52d5\u614b\uff08PK\/PD\uff09\u3092\u4e21\u7acb\u3055\u305b\u305f\u85ac\u5264\u3067\u3059\u3002<strong>\u814e\u79fb\u690d\u306b\u304a\u3051\u308bVCS\u3068TAC\u306e\u6bd4\u8f03\u8a66\u9a13<\/strong>\u3067\u3042\u308bPROMISE\u8a66\u9a13\u306e\u7d50\u679c\u3092\u8981\u7d04\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u3010PICO\uff1aPROMISE\u8a66\u9a13\u306e\u30c7\u30b6\u30a4\u30f3\u3011<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>P\uff08Patient\uff09<\/strong>: \u4f4e\u30ea\u30b9\u30af\u306e\u521d\u56de\u814e\u79fb\u690d\u30ec\u30b7\u30d4\u30a8\u30f3\u30c8\uff08\u4ea1\u5931\u30c9\u30ca\u30fc\u307e\u305f\u306f\u751f\u5b58\u30c9\u30ca\u30fc\uff09334\u540d\u3002<\/li>\n\n\n\n<li><strong>I\uff08Intervention\uff09<\/strong>: \u30dc\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\uff08VCS\uff09\u306e\u6fc3\u5ea6\u5236\u5fa1\u6295\u4e0e\uff08\u76ee\u6a19\u30c8\u30e9\u30d5\u5024\u306b\u5fdc\u3058\u305fLow, Mid, High\u306e3\u7fa4\uff09\u3002<\/li>\n\n\n\n<li><strong>C\uff08Comparison\uff09<\/strong>: \u30bf\u30af\u30ed\u30ea\u30e0\u30b9\uff08TAC\uff09\u6a19\u6e96\u6295\u4e0e\u7fa4\u3002<\/li>\n\n\n\n<li><strong>O\uff08Outcome\uff09<\/strong>: \u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f6\u30f6\u6708\u6642\u70b9\u306e\u751f\u691c\u8a3c\u660e\u6025\u6027\u62d2\u7d76\u53cd\u5fdc\uff08BPAR\uff09\u306e\u975e\u52a3\u6027\u3002\u526f\u6b21\u8a55\u4fa1\u9805\u76ee\u306f\u814e\u6a5f\u80fd\uff08eGFR\uff09\u3001NODAT\u3001\u8840\u5727\u3001\u8102\u8cea\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u7b49\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u3010\u81e8\u5e8a\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\uff1a\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u306e\u89e3\u6790\u3011<\/strong><\/p>\n\n\n\n<p><strong>1. \u6025\u6027\u62d2\u7d76\u53cd\u5fdc\uff08BPAR\uff09\u306e\u975e\u52a3\u6027<\/strong><\/p>\n\n\n\n<p>6\u30f6\u6708\u6642\u70b9\u306eBPAR\u767a\u73fe\u7387\u306f\u3001VCS Low\u7fa4\uff0810.7%\uff09\u3001Mid\u7fa4\uff089.1%\uff09\u3001High\u7fa4\uff082.3%\uff09\u3067\u3042\u308a\u3001TAC\u7fa4\uff085.8%\uff09\u306b\u5bfe\u3057\u3066\u5168\u7fa4\u3067\u975e\u52a3\u6027\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002VCS\u306e\u66dd\u9732\u91cf\u5897\u52a0\u306b\u4f34\u3044\u62d2\u7d76\u53cd\u5fdc\u7387\u304c\u4f4e\u4e0b\u3059\u308b\u660e\u78ba\u306a\u7528\u91cf\u53cd\u5fdc\u95a2\u4fc2\u304c\u8a8d\u3081\u3089\u308c\u3001\u7279\u306bHigh\u7fa4\u3067\u306f\u6975\u3081\u3066\u4f4e\u3044\u62d2\u7d76\u7387\u3092\u9054\u6210\u3002<\/p>\n\n\n\n<p><strong>2. \u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\uff08NODAT\uff09\u306e\u5927\u5e45\u306a\u4f4e\u6e1b<\/strong><\/p>\n\n\n\n<p>\u7279\u7b46\u3059\u3079\u304d\u77e5\u898b\u306f\u3001\u4ee3\u8b1d\u9762\u3078\u306e\u5f71\u97ff\u304c\u4f4e\u3044\u3053\u3068\u3002NODAT\u306e\u767a\u73fe\u7387\u306f\u3001VCS Low\u7fa4\u30671.6%<strong>\u3067\u3042\u308a\u3001TAC\u7fa4\u306e<\/strong>16.4%\u3068\u6bd4\u8f03\u3057\u3066\u6709\u610f\u306b\u4f4e\u3044\u7d50\u679c\uff08p=0.031\uff09\u3002VCS Mid\u7fa4\uff085.7%\uff09\u3067\u3082TAC\u7fa4\u3088\u308a\u4f4e\u5024\u3067\u3042\u308a\u3001VCS\u306fTAC\u3068\u6bd4\u8f03\u3057\u3066\u81b5\u03b2\u7d30\u80de\u3078\u306e\u6bd2\u6027\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u6291\u5236\u4f5c\u7528\u304c\u4f4e\u3044\u53ef\u80fd\u6027\u3001\u3042\u308b\u3044\u306fCsA\u306b\u8fd1\u3044\u4ee3\u8b1d\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6709\u3059\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u305f\u3002<\/p>\n\n\n\n<p><strong>3. \u814e\u6a5f\u80fd\u3068\u8840\u884c\u52d5\u614b<\/strong><\/p>\n\n\n\n<p>Nankivell\u5f0f\u306b\u3088\u308beGFR\u306f\u3001VCS Low\u7fa4\uff0871 mL\/min\uff09\u3001Mid\u7fa4\uff0872 mL\/min\uff09\u306b\u304a\u3044\u3066TAC\u7fa4\uff0869 mL\/min\uff09\u3068\u540c\u7b49\u3067\u3057\u305f\u304c\u3001VCS High\u7fa4\uff0868 mL\/min\uff09\u3067\u306fTAC\u7fa4\u306b\u5bfe\u3057\u6709\u610f\u306a\u4f4e\u4e0b\u3092\u8a8d\u3081\u305f\uff08p=0.049\uff09\u3002\u3053\u308c\u306f\u9ad8\u7528\u91cfCNI\u306b\u3088\u308b\u8f38\u5165\u7d30\u52d5\u8108\u53ce\u7e2e\u7b49\u306e\u8840\u884c\u52d5\u614b\u7684\u5f71\u97ff\u3092\u53cd\u6620\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u3002\u8840\u5727\u3084\u8102\u8cea\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u3064\u3044\u3066\u306f\u3001\u7fa4\u9593\u306b\u81e8\u5e8a\u7684\u306a\u6709\u610f\u5dee\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002<\/p>\n\n\n\n<p><strong>4. \u85ac\u7269\u52d5\u614b\u5b66\u7684\u7279\u6027\uff08PK\/PD\uff09<\/strong><\/p>\n\n\n\n<p>VCS\u306f\u30c8\u30e9\u30d5\u5024\uff08C0\uff09\u3068\u85ac\u7269\u8840\u4e2d\u6fc3\u5ea6\u6642\u9593\u66f2\u7dda\u4e0b\u9762\u7a4d\uff08AUC\uff09\u306e\u9593\u3067\u6975\u3081\u3066\u9ad8\u3044\u76f8\u95a2\uff08<em>r<\/em>2=0.97\uff09\u3092\u793a\u3057\u3001\u8840\u4e2d\u6fc3\u5ea6\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\uff08TDM\uff09\u306e\u4fe1\u983c\u6027\u304c\u9ad8\u3044\u3053\u3068\u304c\u8a3c\u660e\u3002\u307e\u305f\u3001CsA\u3068\u7570\u306a\u308a\u3001MMF\u4f75\u7528\u6642\u306b\u304a\u3051\u308b\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\uff08MPA\uff09\u306e\u66dd\u9732\u91cf\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u306a\u3044\u3068\u3044\u3046\u3001TAC\u3068\u540c\u69d8\u306e\u5229\u70b9\uff08\u6709\u6a5f\u30a2\u30cb\u30aa\u30f3\u8f38\u9001\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\u3078\u306e\u5e72\u6e09\u304c\u306a\u3044\uff09\u3082\u78ba\u8a8d\u3055\u308c\u305f\u3002<\/p>\n\n\n\n<p><strong>\u3010\u7d50\u8ad6\uff1a\u81f3\u9069\u6cbb\u7642\u57df\u306e\u7b56\u5b9a\u3011<\/strong><\/p>\n\n\n\n<p>\u4e8b\u5f8c\u89e3\u6790\u306b\u3088\u308a\u3001\u62d2\u7d76\u53cd\u5fdc\u3092\u6700\u5c0f\u5316\u3057\u3064\u3064NODAT\u30ea\u30b9\u30af\u3092\u6291\u5236\u3059\u308b\u305f\u3081\u306e\u81f3\u9069\u306a\u30dc\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\u30fb\u30c8\u30e9\u30d5\u76ee\u6a19\u57df\u306f<strong>35\u301c&lt;60 ng\/mL<\/strong>\u3067\u3042\u308b\u3068\u63d0\u5531\u3055\u308c\u305f\u3002\u3053\u306e\u7bc4\u56f2\u5185\u3067\u306f\u3001TAC\u3068\u540c\u7b49\u306e\u62d2\u7d76\u6291\u5236\u80fd\u3092\u7dad\u6301\u3057\u3064\u3064\u3001\u7cd6\u5c3f\u75c5\u767a\u73fe\u7387\u3092\u7d04\u534a\u5206\u306b\u6291\u3048\u3089\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002\u3053\u306e\u3088\u3046\u306b\u8a00\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"398\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-104.jpg\" alt=\"\" class=\"wp-image-3640\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-104.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-104-400x199.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"435\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-105.jpg\" alt=\"\" class=\"wp-image-3641\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-105.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-105-400x218.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"432\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-106.jpg\" alt=\"\" class=\"wp-image-3642\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-106.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-106-400x216.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-107.jpg\" alt=\"\" class=\"wp-image-3643\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-107.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-107-400x218.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"440\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-108.jpg\" alt=\"\" class=\"wp-image-3644\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-108.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-108-400x220.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"434\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-109.jpg\" alt=\"\" class=\"wp-image-3645\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-109.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-109-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"446\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-110.jpg\" alt=\"\" class=\"wp-image-3646\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-110.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-110-400x223.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"433\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-111.jpg\" alt=\"\" class=\"wp-image-3647\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-111.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-111-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-112.jpg\" alt=\"\" class=\"wp-image-3648\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-112.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-112-400x218.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"433\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-113.jpg\" alt=\"\" class=\"wp-image-3649\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-113.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-113-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"433\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-114.jpg\" alt=\"\" class=\"wp-image-3650\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-114.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-114-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"431\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-115.jpg\" alt=\"\" class=\"wp-image-3651\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-115.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-115-400x216.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"430\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-116.jpg\" alt=\"\" class=\"wp-image-3652\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-116.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-116-400x215.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"430\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-117.jpg\" alt=\"\" class=\"wp-image-3653\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-117.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-117-400x215.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"429\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-118.jpg\" alt=\"\" class=\"wp-image-3654\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-118.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-118-400x215.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><em>American Journal of Transplantation<\/em>. 2011;11(12):2675-2684. doi:10.1111\/j.1600-6143.2011.03763.x<\/p>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>\u814e\u79fb\u690d\u5f8c\u306e\u514d\u75ab\u6291\u5236\u7642\u6cd5\u306b\u304a\u3044\u3066\u3001\u30ab\u30eb\u30b7\u30cb\u30e5\u30fc\u30ea\u30f3\u963b\u5bb3\u85ac\uff08CNI\uff09\u306f\u4e2d\u5fc3\u7684\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\uff08TAC\uff09\u3084\u30b7\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\uff08CsA\uff09\u306f\u814e\u6bd2\u6027\u3084\u79fb\u690d\u5f8c&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[50],"class_list":["post-3639","post","type-post","status-publish","format-standard","hentry","category-50"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3639","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/comments?post=3639"}],"version-history":[{"count":1,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3639\/revisions"}],"predecessor-version":[{"id":3655,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3639\/revisions\/3655"}],"wp:attachment":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/media?parent=3639"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/categories?post=3639"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}