{"id":3656,"date":"2026-04-18T22:40:50","date_gmt":"2026-04-18T13:40:50","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=3656"},"modified":"2026-04-18T22:40:51","modified_gmt":"2026-04-18T13:40:51","slug":"post-3656","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-3656\/","title":{"rendered":"SLE\u60a3\u8005\u306b\u304a\u3051\u308b\u30dc\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\u3068\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u30e2\u30d5\u30a7\u30c1\u30eb\u306e\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\uff1aMPA\u66dd\u9732\u91cf\u3078\u306e\u5f71\u97ff\u306a\u3057"},"content":{"rendered":"\n<p>\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\u306e\u91cd\u7be4\u306a\u5408\u4f75\u75c7\u3067\u3042\u308b\u30eb\u30fc\u30d7\u30b9\u814e\u708e\uff08LN\uff09\u306e\u6a19\u6e96\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u30e2\u30d5\u30a7\u30c1\u30eb\uff08MMF\uff09\u3068\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u4f75\u7528\u7642\u6cd5\u306f\u6a19\u6e96\u7642\u6cd5\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u65e2\u5b58\u306e\u30ab\u30eb\u30b7\u30cb\u30e5\u30fc\u30ea\u30f3\u963b\u5bb3\u85ac\uff08CNI\uff09\u3067\u3042\u308b\u30b7\u30af\u30ed\u30b9\u30dd\u30ea\u30f3A\uff08CsA\uff09\u3092\u4f75\u7528\u3059\u308b\u5834\u5408\u3001CsA\u304c\u591a\u5264\u8010\u6027\u95a2\u9023\u86cb\u767d2\uff08MRP2\uff09\u3092\u4ecb\u3057\u305f\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u30b0\u30eb\u30af\u30ed\u30f3\u9178\u62b1\u5408\u4f53\uff08MPAG\uff09\u306e\u80c6\u6c41\u6392\u6cc4\u3092\u963b\u5bb3\u3059\u308b\u305f\u3081\u3001\u8178\u809d\u5faa\u74b0\u304c\u6291\u5236\u3055\u308c\u3001\u6d3b\u6027\u672c\u4f53\u3067\u3042\u308b\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\uff08MPA\uff09\u306e\u66dd\u9732\u91cf\u304c\u6700\u592740%\u4f4e\u4e0b\u3059\u308b\u3068\u3044\u3046\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u306a\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\uff08DDI\uff09\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u30dc\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\uff08VCS\uff09\u306f\u3001CsA\u306e\u30a2\u30df\u30ce\u91781\u6b8b\u57fa\u306b\u69cb\u9020\u6539\u5909\u3092\u52a0\u3048\u305f\u6b21\u4e16\u4ee3\u306eCNI\u3067\u3042\u308a\u3001CN\u3078\u306e\u7d50\u5408\u80fd\u5411\u4e0a\u306b\u3088\u308b\u529b\u4fa1\u306e\u6539\u5584\u3068\u3001\u3088\u308a\u5b89\u5b9a\u3057\u305f\u85ac\u7269\u52d5\u614b\uff08PK\uff09\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6709\u3057\u3066\u3044\u307e\u3059\u3002SLE\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3001\u5b9a\u5e38\u72b6\u614b\u4e0b\u306b\u304a\u3051\u308bVCS\u3068MMF\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u691c\u8a3c\u3057\u305f\u7b2c1\u76f8\u3001\u975e\u76f2\u691c\u3001\u591a\u65bd\u8a2d\u5171\u540c\u8a66\u9a13\u306e\u7d50\u679c\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>\u3010\u8a66\u9a13\u30c7\u30b6\u30a4\u30f3\u3068\u65b9\u6cd5\u3011<\/strong><\/p>\n\n\n\n<p>24\u540d\u306e\u5b89\u5b9a\u3057\u305fSLE\u60a3\u8005\uff08LN\u65e2\u5f8032%\u3092\u542b\u3080\uff09\u3092\u5bfe\u8c61\u3068\u3057\u3001MMF\uff082g\/\u65e5\uff09\u309228\u65e5\u9593\u4ee5\u4e0a\u670d\u7528\u3057\u3066\u5b9a\u5e38\u72b6\u614b\u306b\u3042\u308b\u3053\u3068\u304c\u6761\u4ef6\u3002\u3053\u308c\u306bVCS\uff0823.7mg BID\uff09\u30927\u65e5\u9593\u8ffd\u52a0\u6295\u4e0e\u3057\u3001\u6295\u4e0e1\u65e5\u76ee\uff08MMF\u5358\u72ec\uff09\u30687\u65e5\u76ee\uff08MMF+VCS\uff09\u306b\u304a\u3051\u308bMPA\u304a\u3088\u3073MPAG\u306ePK\u30d1\u30e9\u30e1\u30fc\u30bf\u3092\u975e\u30b3\u30f3\u30d1\u30fc\u30c8\u30e1\u30f3\u30c8\u89e3\u6790\u306b\u3088\u308a\u6bd4\u8f03\u691c\u8a0e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p><strong>\u3010\u4e3b\u8981\u306a\u7814\u7a76\u7d50\u679c\u3011<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MPA\u66dd\u9732\u91cf\u306e\u4e00\u8cab\u6027<\/strong>: \u5e7e\u4f55\u5e73\u5747\u6bd4\u306e\u89e3\u6790\u306b\u304a\u3044\u3066\u3001VCS\u4f75\u7528\u4e0b\u3067\u306eMPA\u306e<em>C<\/em><em>ma<\/em><em>x<\/em>\u200b\u304a\u3088\u3073<em>A<\/em><em>U<\/em><em>C<\/em>0\u221212\u200b\u306e\u6cbb\u7642\u6bd4\u306f\u305d\u308c\u305e\u308c0.94\u304a\u3088\u30731.09\u3067\u3042\u308a\u3001\u540c\u7b49\u6027\u306e\u95be\u5024\uff080.80\u20131.25\uff09\u306e\u7bc4\u56f2\u5185\u3067\u3057\u305f\u3002\u3064\u307e\u308a\u3001VCS\u306fMMF\u306e\u6d3b\u6027\u4ee3\u8b1d\u7269\u3067\u3042\u308bMPA\u306e\u8840\u4e2d\u6fc3\u5ea6\u306b\u81e8\u5e8a\u7684\u306b\u610f\u5473\u306e\u3042\u308b\u5f71\u97ff\u3092\u4e0e\u3048\u306a\u3044\u3053\u3068\u304c\u8a3c\u660e\u3055\u308c\u307e\u3057\u305f\u3002<\/li>\n\n\n\n<li><strong>MPAG\u306e\u63a8\u79fb<\/strong>: \u85ac\u7406\u5b66\u7684\u306b\u4e0d\u6d3b\u6027\u306a\u4ee3\u8b1d\u7269\u3067\u3042\u308bMPAG\u306e\u66dd\u9732\u91cf\u306f\u3001VCS\u4f75\u7528\u306b\u3088\u308a\u308f\u305a\u304b\u306b\u4e0a\u6607\uff08<em>C<\/em><em>ma<\/em><em>x<\/em>\u200b\u306712%\u3001<em>A<\/em><em>U<\/em><em>C<\/em>0\u221212\u200b\u306727%\u5897\uff09\u3057\u307e\u3057\u305f\u304c\u3001\u814e\u6a5f\u80fd\u306f\u5b89\u5b9a\u3057\u3066\u304a\u308a\u3001\u81e8\u5e8a\u7684\u306a\u610f\u7fa9\u306f\u4e4f\u3057\u3044\u3068\u5224\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/li>\n\n\n\n<li><strong>\u5b89\u5168\u6027\u3068\u5fcd\u5bb9\u6027<\/strong>: VCS\u3068MMF\u306e\u4f75\u7528\u306f\u826f\u597d\u306a\u5fcd\u5bb9\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u3084\u6b7b\u4ea1\u4f8b\u3001\u4e2d\u6b62\u306b\u81f3\u308b\u6cbb\u7642\u95a2\u9023\u526f\u4f5c\u7528\u306f\u8a8d\u3081\u3089\u308c\u305a\u3001eGFR\u3084SLE\u75be\u60a3\u6d3b\u52d5\u6027\u30b9\u30b3\u30a2\u3082\u8a66\u9a13\u671f\u9593\u3092\u901a\u3058\u3066\u5b89\u5b9a\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u3010\u7d50\u8ad6\u3068\u81e8\u5e8a\u7684\u610f\u7fa9\u3011<\/strong><\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u306b\u3088\u308a\u3001\u30dc\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\u306fCsA\u3068\u306f\u7570\u306a\u308a\u3001MMF\u3068\u306e\u9593\u306b\u81e8\u5e8a\u7684\u306b\u554f\u984c\u3068\u306a\u308bDDI\u3092\u5f15\u304d\u8d77\u3053\u3055\u306a\u3044\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002MMF\u306e\u66dd\u9732\u91cf\u5909\u52d5\u306f\u6cbb\u7642\u306e\u6709\u52b9\u6027\u3084\u5b89\u5168\u6027\u306b\u76f4\u7d50\u3059\u308b\u305f\u3081\u3001\u7528\u91cf\u8abf\u7bc0\u3092\u5fc5\u8981\u3068\u305b\u305a\u306b\u3053\u308c\u3089\u4e8c\u5264\u3092\u4f75\u7528\u3067\u304d\u308b\u3053\u3068\u306f\u3001LN\u306e\u5bdb\u89e3\u5c0e\u5165\u30fb\u7dad\u6301\u7642\u6cd5\u306b\u304a\u3051\u308b\u5927\u304d\u306a\u5f37\u307f\u3068\u306a\u308a\u307e\u3059\u3002VCS\u3001MMF\u3001\u304a\u3088\u3073\u4f4e\u7528\u91cf\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u4e09\u5264\u4f75\u7528\u7642\u6cd5\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u7d2f\u7a4d\u6bd2\u6027\u3092\u6291\u3048\u3064\u3064\u65e9\u671f\u306e\u5b8c\u5168\u5bdb\u89e3\u3092\u76ee\u6307\u3059\u305f\u3081\u306e\u3001\u4e88\u6e2c\u53ef\u80fd\u6027\u306e\u9ad8\u3044\u5f37\u529b\u306a\u6226\u7565\u3067\u3042\u308b\u3068\u7d50\u8ad6\u4ed8\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"434\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-119.jpg\" alt=\"\" class=\"wp-image-3657\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-119.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-119-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"434\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-120.jpg\" alt=\"\" class=\"wp-image-3658\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-120.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-120-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"435\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-121.jpg\" alt=\"\" class=\"wp-image-3659\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-121.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-121-400x218.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"437\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-122.jpg\" alt=\"\" class=\"wp-image-3660\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-122.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-122-400x219.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"434\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-123.jpg\" alt=\"\" class=\"wp-image-3661\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-123.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-123-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"438\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-124.jpg\" alt=\"\" class=\"wp-image-3662\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-124.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-124-400x219.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"433\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-125.jpg\" alt=\"\" class=\"wp-image-3663\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-125.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-125-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"433\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-126.jpg\" alt=\"\" class=\"wp-image-3664\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-126.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-126-400x217.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"438\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-127.jpg\" alt=\"\" class=\"wp-image-3665\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-127.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-127-400x219.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-128.jpg\" alt=\"\" class=\"wp-image-3666\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-128.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-128-400x218.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"435\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-129.jpg\" alt=\"\" class=\"wp-image-3667\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-129.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/04\/image-21-129-400x218.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><em>Nephrology Dialysis Transplantation<\/em>. 2022;37(5):917\u2013922. doi:10.1093\/ndt\/gfab022.<\/p>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\u306e\u91cd\u7be4\u306a\u5408\u4f75\u75c7\u3067\u3042\u308b\u30eb\u30fc\u30d7\u30b9\u814e\u708e\uff08LN\uff09\u306e\u6a19\u6e96\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u30e2\u30d5\u30a7\u30c1\u30eb\uff08MMF\uff09\u3068\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u4f75\u7528\u7642\u6cd5\u306f\u6a19\u6e96\u7642\u6cd5&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[50],"class_list":["post-3656","post","type-post","status-publish","format-standard","hentry","category-50"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3656","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/comments?post=3656"}],"version-history":[{"count":1,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3656\/revisions"}],"predecessor-version":[{"id":3668,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3656\/revisions\/3668"}],"wp:attachment":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/media?parent=3656"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/categories?post=3656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}