{"id":3669,"date":"2026-04-20T20:11:47","date_gmt":"2026-04-20T11:11:47","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=3669"},"modified":"2026-04-20T20:11:47","modified_gmt":"2026-04-20T11:11:47","slug":"post-3669","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-3669\/","title":{"rendered":"\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306b\u304a\u3051\u308b\u767a\u75c7\u6642\u671f\u5225\u306e\u4e88\u5f8c\u4e88\u6e2c\u3068\u96e3\u6cbb\u4f8b\u306b\u5bfe\u3059\u308b\u30de\u30eb\u30c1\u30bf\u30fc\u30b2\u30c3\u30c8\u7642\u6cd5\u306e\u81e8\u5e8a\u7684\u6709\u52b9\u6027"},"content":{"rendered":"\n

\u30eb\u30fc\u30d7\u30b9\u814e\u708e\uff08LN\uff09\u306f\u3001\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\u306e\u4e88\u5f8c\u3092\u5de6\u53f3\u3059\u308b\u6700\u91cd\u8981\u306e\u81d3\u5668\u75c5\u5909\u3067\u3042\u308a\u3001\u6210\u4eba\u60a3\u8005\u306e50\u301c60\uff05\u306b\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002\u6cbb\u7642\u306e\u30d1\u30e9\u30c0\u30a4\u30e0\u306f\u3001\u814e\u6a5f\u80fd\u306e\u4fdd\u6301\u3068\u751f\u5b58\u7387\u6539\u5584\u3092\u76ee\u7684\u3068\u3057\u305f\u65e9\u671f\u306e\u5b8c\u5168\u814e\u5bdb\u89e3\uff08CR\uff09\u9054\u6210<\/strong>\u306b\u7f6e\u304b\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u65e5\u672c\u4eba\u30b3\u30db\u30fc\u30c8\u3092\u5bfe\u8c61\u3068\u3057\u305f\u591a\u65bd\u8a2d\u5171\u540c\u7814\u7a76\u306b\u3088\u308c\u3070\u3001SLE\u8a3a\u65ad\u304b\u30895\u5e74\u4ee5\u5185\u306e\u300c\u65e9\u671f\u767a\u75c7\u578bLN\uff08Early-onset\uff09<\/strong>\u300d\u30685\u5e74\u4ee5\u964d\u306e\u300c\u9045\u5ef6\u767a\u75c7\u578bLN\uff08Late-onset\uff09<\/strong>\u300d\u3067\u306f\u81e8\u5e8a\u7684\u4e88\u5f8c\u304c\u7570\u306a\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u591a\u5909\u91cf\u89e3\u6790\u306b\u304a\u3044\u3066\u3001\u65e9\u671f\u767a\u75c7\u578bLN\u306f\u6cbb\u7642\u958b\u59cb6\u30f6\u6708\uff08OR 2.39\uff09\u304a\u3088\u307312\u30f6\u6708\uff08OR 2.10\uff09\u6642\u70b9\u3067\u306eCR\u9054\u6210\u306e\u72ec\u7acb\u3057\u305f\u4e88\u6e2c\u56e0\u5b50\u3067\u3042\u308a\u3001\u9045\u5ef6\u767a\u75c7\u578b\u3068\u6bd4\u8f03\u3057\u3066\u5168\u751f\u5b58\u7387\u3082\u6709\u610f\u306b\u826f\u597d\u3067\u3057\u305f\u3002\u4e00\u65b9\u3001\u9045\u5ef6\u767a\u75c7\u578bLN\u3067\u306f\u3001\u9577\u671f\u306b\u308f\u305f\u308b\u526f\u814e\u76ae\u8cea\u30b9\u30c6\u30ed\u30a4\u30c9\u3084\u514d\u75ab\u6291\u5236\u5264\u3078\u306e\u66dd\u9732\u304c\u5fc3\u8840\u7ba1\u5408\u4f75\u75c7\u3084\u91cd\u75c7\u611f\u67d3\u75c7\u3092\u8a98\u767a\u3057\u3001\u6b7b\u4ea1\u7387\u4e0a\u6607\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u6cbb\u7642\u62b5\u6297\u6027\uff08Refractory\uff09\u3092\u793a\u3059\u75c7\u4f8b\u3084\u3001\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u30e2\u30d5\u30a7\u30c1\u30eb\uff08MMF\uff09\u307e\u305f\u306f\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\uff08TAC\uff09\u5358\u5264\u7642\u6cd5\u3067\u5341\u5206\u306a\u53cd\u5fdc\u304c\u5f97\u3089\u308c\u306a\u3044\u75c7\u4f8b\u306b\u5bfe\u3057\u3066\u306f\u3001\u30de\u30eb\u30c1\u30bf\u30fc\u30b2\u30c3\u30c8\u7642\u6cd5\uff08\u591a\u6a19\u7684\u7642\u6cd5\uff09<\/strong>\u6297\u86cb\u767d\u5c3f\u4f5c\u7528<\/strong>\u3082\u6709\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u5b89\u5168\u6027\u306b\u95a2\u3057\u3066\u306f\u3001\u591a\u5264\u4f75\u7528\u306b\u3088\u308b\u514d\u75ab\u6291\u5236\u306e\u5897\u5f37\u306b\u4f34\u3044\u5e2f\u72b6\u75b1\u75b9\u3084\u80ba\u708e\u306a\u3069\u306e\u611f\u67d3\u75c7\u30ea\u30b9\u30af\u306b\u7559\u610f\u304c\u5fc5\u8981\u3067\u3059\u304c\u3001\u591a\u304f\u306f\u7ba1\u7406\u53ef\u80fd\u3067\u3042\u308a\u3001\u9577\u671f\u7684\u306aESKD\u56de\u907f\u304a\u3088\u3073\u751f\u547d\u4e88\u5f8c\u6539\u5584\u306e\u305f\u3081\u306e\u6709\u529b\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3068\u306a\u308a\u5f97\u307e\u3059\u3002<\/p>\n\n\n\n

\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u3001\u6700\u65b0\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u304d\u3001\u75c7\u72b6\u306e\u80cc\u666f\u306b\u3042\u308b\u300c\u4f53\u306e\u4ed5\u7d44\u307f\u300d\u307e\u3067\u4e01\u5be7\u306b\u8aac\u660e\u3057\u306a\u304c\u3089\u3001\u5185\u79d1\u30fb\u30ea\u30a6\u30de\u30c1\u30fb\u81a0\u539f\u75c5\u8a3a\u7642\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u8907\u96d1\u306a\u75c5\u614b\u3092\u6301\u3064\u30eb\u30fc\u30d7\u30b9\u814e\u708e\u306b\u304a\u3044\u3066\u3082\u3001\u60a3\u8005\u69d8\u304c\u300c\u306a\u305c\u3053\u306e\u591a\u5264\u4f75\u7528\u304c\u5fc5\u8981\u306a\u306e\u304b\u300d\u3092\u6df1\u304f\u7406\u89e3\u3057\u3001\u7d0d\u5f97\u3057\u3066\u6cbb\u7642\u3092\u7d99\u7d9a\u3067\u304d\u308b\u74b0\u5883\u4f5c\u308a\u3092\u5927\u5207\u306b\u3057\u3066\u3044\u307e\u3059\u3002 \u67cf\u5e02\u30fb\u6211\u5b6b\u5b50\u5e02\u5468\u8fba\u3067\u3001\u95a2\u7bc0\u306e\u75db\u307f\u3084\u86cb\u767d\u5c3f\u306a\u3069\u3001\u539f\u56e0\u306e\u5206\u304b\u3089\u306a\u3044\u4f53\u8abf\u4e0d\u826f\u306b\u304a\u60a9\u307f\u306e\u65b9\u306f\u3001\u3069\u3046\u305e\u304a\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\"\"<\/figure>\n\n\n\n
\n

Arthritis Res Ther<\/em>. 2020;22(1):170.<\/p>\n\n\n\n

Clin Exp Rheumatol<\/em>. 2019;37(1):89-96.<\/p>\n\n\n\n

Nephrol Dial Transplant<\/em>. 2010;25(12):3939-3948.<\/p>\n\n\n\n

Int J Clin Rheumatol<\/em>. 2013;8(1):61-72.<\/p>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":"

\u30eb\u30fc\u30d7\u30b9\u814e\u708e\uff08LN\uff09\u306f\u3001\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09\u306e\u4e88\u5f8c\u3092\u5de6\u53f3\u3059\u308b\u6700\u91cd\u8981\u306e\u81d3\u5668\u75c5\u5909\u3067\u3042\u308a\u3001\u6210\u4eba\u60a3\u8005\u306e50\u301c60\uff05\u306b\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002\u6cbb\u7642\u306e\u30d1\u30e9\u30c0\u30a4\u30e0\u306f\u3001\u814e\u6a5f\u80fd…<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[64,1],"class_list":["post-3669","post","type-post","status-publish","format-standard","hentry","category-sle","category-medical_science"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3669","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/comments?post=3669"}],"version-history":[{"count":1,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3669\/revisions"}],"predecessor-version":[{"id":3684,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/posts\/3669\/revisions\/3684"}],"wp:attachment":[{"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/media?parent=3669"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-json\/wp\/v2\/categories?post=3669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}