{"id":6901,"date":"2026-07-18T10:49:55","date_gmt":"2026-07-18T01:49:55","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=6901"},"modified":"2026-07-18T10:49:56","modified_gmt":"2026-07-18T01:49:56","slug":"post-6901","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-6901\/","title":{"rendered":"\u96e3\u6cbb\u6027\u3066\u3093\u304b\u3093\uff1a\u30c9\u30e9\u30d9\u75c7\u5019\u7fa4\u306b\u5bfe\u3059\u308bZorevunersen\u306e\u7b2c1\/2a\u76f8\u8a66\u9a13\u3002\u5931\u308f\u308c\u305f\u30d6\u30ec\u30fc\u30ad\u3092\u5fa9\u5143\u3059\u308b\u65b0\u85ac\u3068\u8133\u306e\u4f53\u306e\u4ed5\u7d44\u307f\u3092\u67cf\u6211\u5b6b\u5b50\u306e\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u304c\u89e3\u8aac"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u85ac\u304c\u52b9\u304b\u306a\u3044\u91cd\u3044\u767a\u4f5c\u3068\u767a\u9054\u306e\u9045\u308c\u3002\u907a\u4f1d\u5b50\u306e\u30a8\u30e9\u30fc\u3092\u76f4\u63a5\u4fee\u6b63\u3057\u3001\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u80fd\u529b\u307e\u3067\u6539\u5584\u3059\u308b\u6b21\u4e16\u4ee3\u306e\u5e0c\u671b<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u300c\u30c9\u30e9\u30d9\uff08Dravet\uff09\u75c7\u5019\u7fa4\u300d\u306f\u3001\u4e73\u5e7c\u5150\u671f\u306b\u767a\u75c7\u3057\u3001\u65e2\u5b58\u306e\u6297\u3066\u3093\u304b\u3093\u85ac\u304c\u307b\u3068\u3093\u3069\u52b9\u304b\u306a\u3044\u91cd\u7be4\u306a\u3051\u3044\u308c\u3093\u767a\u4f5c\u3092\u7e70\u308a\u8fd4\u3059\u6307\u5b9a\u96e3\u75c5\u3067\u3059\u3002\u767a\u4f5c\u3060\u3051\u3067\u306a\u304f\u3001\u6210\u9577\u306b\u4f34\u3063\u3066\u8a00\u8449\u306e\u9045\u308c\u3084\u77e5\u7684\u969c\u5bb3\u3001\u884c\u52d5\u7570\u5e38\u304c\u73fe\u308c\u3001\u3066\u3093\u304b\u3093\u306b\u3088\u308b\u7a81\u7136\u6b7b\uff08SUDEP\uff09\u306e\u30ea\u30b9\u30af\u3082\u9ad8\u3044\u3068\u3044\u3046\u904e\u9177\u306a\u75c5\u6c17\u3067\u3059\u3002 \u4eca\u56de\u3001\u6a29\u5a01\u533b\u5b66\u8a8c\u300eThe New England Journal of Medicine\uff08NEJM\uff09\u300f\u306b\u3066\u3001\u3053\u306e\u30c9\u30e9\u30d9\u75c7\u5019\u7fa4\u306e\u300c\u6839\u672c\u7684\u306a\u539f\u56e0\u300d\u306b\u76f4\u63a5\u30a2\u30d7\u30ed\u30fc\u30c1\u3059\u308b\u5168\u304f\u65b0\u3057\u3044\u907a\u4f1d\u5b50\u6a19\u7684\u85ac\u300czorevunersen\uff08\u30be\u30ec\u30d6\u30cd\u30eb\u30bb\u30f3\uff09\u300d\u306e\u81e8\u5e8a\u8a66\u9a13\uff08\u7b2c1\/2a\u76f8\u8a66\u9a13\uff09\u306e\u753b\u671f\u7684\u306a\u7d50\u679c\u304c\u767a\u8868\u3055\u308c\u307e\u3057\u305f\u3002\u4eca\u56de\u306f\u3053\u306e\u6700\u65b0\u30c7\u30fc\u30bf\u306b\u57fa\u3065\u304d\u3001\u8133\u306e\u8208\u596e\u304c\u6b62\u307e\u3089\u306a\u304f\u306a\u308b\u300c\u4f53\u306e\u4ed5\u7d44\u307f\u300d\u3068\u3001\u75c5\u6c17\u306e\u9032\u884c\u305d\u306e\u3082\u306e\u3092\u5909\u3048\u308b\u672a\u6765\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066\u67cf\u6211\u5b6b\u5b50\u306e\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u304c\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1. \u8133\u306e\u300c\u30d6\u30ec\u30fc\u30ad\u300d\u304c\u8db3\u308a\u306a\u304f\u306a\u308b\u4f53\u306e\u4ed5\u7d44\u307f<\/strong> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30c9\u30e9\u30d9\u75c7\u5019\u7fa4\u306e\u6700\u3082\u5927\u304d\u306a\u539f\u56e0\u306f\u3001\u751f\u307e\u308c\u3064\u304d\u300cSCN1A\u300d\u3068\u3044\u3046\u907a\u4f1d\u5b50\u306b\u30a8\u30e9\u30fc\uff08\u5909\u7570\uff09\u304c\u3042\u308b\u3053\u3068\u3067\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306f\u3001\u8133\u306e\u795e\u7d4c\u7d30\u80de\u3092\u843d\u3061\u7740\u304b\u305b\u308b\u305f\u3081\u306e\u300c\u30d6\u30ec\u30fc\u30ad\uff08NaV1.1\u30ca\u30c8\u30ea\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb\uff09\u300d\u3092\u4f5c\u308b\u8a2d\u8a08\u56f3\u306e\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002 \u3057\u304b\u3057\u3001\u907a\u4f1d\u5b50\u306b\u30a8\u30e9\u30fc\u304c\u3042\u308b\u3068\u3001\u3053\u306e\u30d6\u30ec\u30fc\u30ad\u5f79\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u5341\u5206\u306a\u91cf\u4f5c\u3089\u308c\u306a\u304f\u306a\u308a\u307e\u3059\uff08\u30cf\u30d7\u30ed\u4e0d\u5168\uff09\u3002\u305d\u306e\u7d50\u679c\u3001\u8133\u5185\u306e\u300c\u8208\u596e\u300d\u3068\u300c\u6291\u5236\uff08\u30d6\u30ec\u30fc\u30ad\uff09\u300d\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u3066\u5168\u4f53\u304c\u904e\u8208\u596e\u72b6\u614b\u306b\u9665\u308a\u3001\u6fc0\u3057\u3044\u3051\u3044\u308c\u3093\u767a\u4f5c\u3084\u767a\u9054\u306e\u9045\u308c\u3092\u5f15\u304d\u8d77\u3053\u3059\u3068\u3044\u3046\u4f53\u306e\u4ed5\u7d44\u307f\u304c\u50cd\u3044\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002\u3053\u308c\u307e\u3067\u306e\u85ac\u306f\u300c\u767a\u4f5c\u3092\u6291\u3048\u8fbc\u3080\u300d\u3053\u3068\u3057\u304b\u3067\u304d\u305a\u3001\u3053\u306e\u6839\u672c\u7684\u306a\u30d6\u30ec\u30fc\u30ad\u4e0d\u8db3\u3092\u89e3\u6d88\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2. \u907a\u4f1d\u5b50\u306e\u300c\u7121\u99c4\u306a\u90e8\u5206\u300d\u3092\u30b9\u30ad\u30c3\u30d7\u3055\u305b\u308b\u65b0\u85ac<\/strong> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u958b\u767a\u3055\u308c\u305f\u300czorevunersen\u300d\u306f\u3001\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u30aa\u30ea\u30b4\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\uff08ASO\uff09\u3068\u547c\u3070\u308c\u308b\u6700\u5148\u7aef\u306e\u6838\u9178\u533b\u85ac\u54c1\u3067\u3059\u3002 \u4eba\u9593\u306e\u4f53\u306f\u3001\u907a\u4f1d\u5b50\uff08DNA\uff09\u304b\u3089\u8a2d\u8a08\u56f3\uff08mRNA\uff09\u3092\u30b3\u30d4\u30fc\u3057\u3066\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4f5c\u308a\u307e\u3059\u304c\u3001\u30c9\u30e9\u30d9\u75c7\u5019\u7fa4\u3067\u306f\u8a2d\u8a08\u56f3\u306e\u9014\u4e2d\u306b\u300c\u7121\u99c4\u306a\u90e8\u5206\uff08\u30dd\u30a4\u30ba\u30f3\u30a8\u30af\u30bd\u30f3\uff09\u300d\u304c\u6df7\u3056\u3063\u3066\u3057\u307e\u3044\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3046\u307e\u304f\u4f5c\u3089\u308c\u307e\u305b\u3093\u3002zorevunersen\u306f\u3001\u3053\u306e\u8a2d\u8a08\u56f3\u306b\u30d4\u30bf\u30c3\u3068\u304f\u3063\u3064\u3044\u3066\u300c\u7121\u99c4\u306a\u90e8\u5206\u3092\u8aad\u307f\u98db\u3070\u3059\uff08\u30b9\u30ad\u30c3\u30d7\u3059\u308b\uff09\u300d\u3088\u3046\u306b\u50cd\u304d\u304b\u3051\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u6b63\u5e38\u306a\u8a2d\u8a08\u56f3\u304c\u5927\u91cf\u306b\u4f5c\u3089\u308c\u3001\u4e0d\u8db3\u3057\u3066\u3044\u305f\u300c\u8133\u306e\u30d6\u30ec\u30fc\u30ad\uff08NaV1.1\uff09\u300d\u306e\u91cf\u304c\u5143\u901a\u308a\u306b\u5897\u3048\u308b\u3068\u3044\u3046\u3001\u6975\u3081\u3066\u7cbe\u5bc6\u306a\u4f53\u306e\u4ed5\u7d44\u307f\u3092\u5229\u7528\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>3. \u767a\u4f5c\u306e\u6fc0\u6e1b\u3068\u300c\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u80fd\u529b\u300d\u306e\u6539\u5584<\/strong> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u8a66\u9a13\u3067\u306f\u3001\u65e2\u5b58\u306e\u85ac\u3067\u767a\u4f5c\u304c\u6291\u3048\u3089\u308c\u306a\u30442\u6b73\u304b\u308918\u6b73\u306e\u60a3\u8005\u69d8\u306b\u5bfe\u3057\u3001\u8170\u690e\u7a7f\u523a\uff08\u80cc\u4e2d\u304b\u3089\u306e\u6ce8\u5c04\uff09\u3067zorevunersen\u304c\u9ac4\u6db2\u5185\u306b\u6295\u4e0e\u3055\u308c\u307e\u3057\u305f\u3002 \u6700\u3082\u9ad8\u3044\u7528\u91cf\uff0870mg\uff09\u3092\u6295\u4e0e\u3055\u308c\u3001\u305d\u306e\u5f8c\u306e\u5ef6\u9577\u8a66\u9a13\u306b\u53c2\u52a0\u3057\u305f\u60a3\u8005\u69d8\u3067\u306f\u3001\u3051\u3044\u308c\u3093\u767a\u4f5c\u306e\u983b\u5ea6\u304c\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u3089\u300c58.8%\u301c90.9%\u3082\u6e1b\u5c11\u3059\u308b\u300d\u3068\u3044\u3046\u5287\u7684\u306a\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u9a5a\u304f\u3079\u304d\u3053\u3068\u306b\u3001\u3053\u308c\u307e\u3067\u306e\u85ac\u3067\u306f\u6539\u5584\u304c\u96e3\u3057\u304b\u3063\u305f\u300c\u81ea\u5206\u306e\u610f\u601d\u3092\u4f1d\u3048\u308b\u529b\uff08\u8868\u51fa\u8a00\u8a9e\uff09\u300d\u3084\u300c\u8a00\u8449\u3092\u7406\u89e3\u3059\u308b\u529b\uff08\u53d7\u5bb9\u8a00\u8a9e\uff09\u300d\u3068\u3044\u3063\u305f\u9069\u5fdc\u884c\u52d5\uff08Vineland-3\u30b9\u30b3\u30a2\uff09\u306b\u3082\u660e\u78ba\u306a\u6539\u5584\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002\u767a\u4f5c\u3060\u3051\u3067\u306a\u304f\u3001\u8133\u306e\u6a5f\u80fd\u305d\u306e\u3082\u306e\u304c\u56de\u5fa9\u3057\u3064\u3064\u3042\u308b\u3053\u3068\u3092\u793a\u3059\u753b\u671f\u7684\u306a\u30c7\u30fc\u30bf\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>4. \u5b89\u5168\u6027\u3068\u672a\u6765\u3078\u306e\u5c55\u671b<\/strong> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65b0\u3057\u3044\u304a\u85ac\u3067\u3042\u308b\u305f\u3081\u5b89\u5168\u6027\u3082\u614e\u91cd\u306b\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002\u6700\u3082\u591a\u304f\u898b\u3089\u308c\u305f\u526f\u4f5c\u7528\u306f\u3001\u8170\u690e\u7a7f\u523a\u306b\u4f34\u3046\u75c7\u72b6\u3084\u3001\u9ac4\u6db2\u4e2d\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u4e00\u904e\u6027\u306e\u4e0a\u6607\uff0845%\uff09\u3067\u3057\u305f\u304c\u3001\u91cd\u7be4\u306a\u3082\u306e\u306f\u5c11\u306a\u304f\u3001\u5b89\u5168\u306b\u7ba1\u7406\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u30c9\u30e9\u30d9\u75c7\u5019\u7fa4\u306e\u6cbb\u7642\u306f\u3001\u5358\u306a\u308b\u300c\u5bfe\u75c7\u7642\u6cd5\u300d\u304b\u3089\u3001\u75c5\u6c17\u306e\u539f\u56e0\u305d\u306e\u3082\u306e\u3092\u6cbb\u7642\u3059\u308b\u300c\u75be\u60a3\u4fee\u98fe\u7642\u6cd5\u300d\u306e\u6642\u4ee3\u3078\u3068\u5927\u304d\u306a\u4e00\u6b69\u3092\u8e0f\u307f\u51fa\u3057\u307e\u3057\u305f\u3002\u73fe\u5728\u3001\u3055\u3089\u306b\u5927\u898f\u6a21\u306a\u7b2c3\u76f8\u8a66\u9a13\u304c\u9032\u884c\u4e2d\u3067\u3042\u308a\u3001\u4e00\u65e5\u3082\u65e9\u3044\u5b9f\u7528\u5316\u304c\u5f85\u3061\u671b\u307e\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af<\/strong>\u3067\u306f\u3001\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u306e\u8996\u70b9\u304b\u3089\u3001\u907a\u4f1d\u5b50\u3084\u514d\u75ab\u306e\u7570\u5e38\u304c\u3069\u306e\u3088\u3046\u306b\u3057\u3066\u5168\u8eab\u306e\u75c5\u6c17\u3092\u5f15\u304d\u8d77\u3053\u3059\u306e\u304b\u3068\u3044\u3046**\u300c\u4f53\u306e\u4ed5\u7d44\u307f\u300d\u3092\u4e01\u5be7\u306b\u7d10\u89e3\u304d\u306a\u304c\u3089**\u3001\u7686\u69d8\u306e\u30c8\u30fc\u30bf\u30eb\u306a\u5065\u5eb7\u7ba1\u7406\u3092\u30b5\u30dd\u30fc\u30c8\u3044\u305f\u3057\u307e\u3059\u3002\u5f53\u9662\u3067\u306f\u5c0f\u5150\u306e\u96e3\u6cbb\u6027\u3066\u3093\u304b\u3093\u306e\u76f4\u63a5\u7684\u306a\u6cbb\u7642\u306f\u884c\u3063\u3066\u304a\u308a\u307e\u305b\u3093\u304c\u3001\u6301\u75c5\u3092\u6301\u3064\u60a3\u8005\u69d8\u3084\u305d\u306e\u3054\u5bb6\u65cf\u306e\u611f\u67d3\u75c7\u4e88\u9632\uff08\u80ba\u708e\u7403\u83cc\u3084\u5e2f\u72b6\u75b1\u75b9\u306a\u3069\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\uff09\u3001\u304a\u3088\u3073\u3066\u3093\u304b\u3093\u767a\u4f5c\u306b\u3088\u308b\u5916\u50b7\u30ea\u30b9\u30af\u3084\u98f2\u307f\u8fbc\u307f\u306e\u4f4e\u4e0b\uff08\u8aa4\u56a5\uff09\u3092\u9632\u3050\u305f\u3081\u306e\u5fb9\u5e95\u3057\u305f\u533b\u79d1\u6b6f\u79d1\u9023\u643a\u3092\u901a\u3058\u3001\u5b89\u5fc3\u3067\u304d\u308b\u751f\u6d3b\u74b0\u5883\u3065\u304f\u308a\u3092\u3054\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002<strong>\u5f53\u9662\u306e\u5185\u79d1\uff08\u30ea\u30a6\u30de\u30c1\u30fb\u81a0\u539f\u75c5\u8a3a\u7642\uff09\u30fb\u767a\u71b1\u5916\u6765\u306f\u571f\u66dc\u65e5\u306e\u5348\u5f8c\u308217\u6642\u307e\u3067<\/strong>\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u3001\u5e73\u65e5\u304a\u5fd9\u3057\u3044\u65b9\u306e\u3054\u76f8\u8ac7\u306b\u3082\u3057\u3063\u304b\u308a\u5bfe\u5fdc\u3044\u305f\u3057\u307e\u3059\u3002\u307e\u305f\u3001<strong>\u5f53\u9662\u306e\u6b6f\u79d1\u306f\u571f\u66dc\u65e5\u5348\u5f8c2\u6642\uff0814\u6642\uff09\u307e\u3067<\/strong>\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002\u67cf\u30fb\u6211\u5b6b\u5b50\u30a8\u30ea\u30a2\u3067\u5168\u8eab\u306e\u30c8\u30fc\u30bf\u30eb\u30b1\u30a2\u3092\u3054\u5e0c\u671b\u306e\u65b9\u306f\u3001\u304b\u304b\u308a\u3064\u3051\u533b\u3067\u3042\u308b\u5f53\u9662\u3078\u304a\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u25a0 \u53d7\u8a3a\u3092\u3054\u5e0c\u671b\u306e\u65b9\u3078<br>\ud83d\udc49 \u3010\u533b\u79d1\u3011\uff08\u7dcf\u5408\u5185\u79d1\u30fb\u30ea\u30a6\u30de\u30c1\u5c02\u9580\u533b\uff09WEB\u4e88\u7d04\u306f\u3053\u3061\u3089<a href=\"https:\/\/melmo-app.com\/clinic\/673d5e08785f0f0030870bdb\/reservation?method=visit\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/melmo-app.com\/clinic\/673d5e08785f0f0030870bdb\/reservation?method=visit<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udc49 \u3010\u6b6f\u79d1\u3011\uff08\u30c9\u30e9\u30a4\u30de\u30a6\u30b9\u30fb\u81a0\u539f\u75c5\u95a2\u9023\u53e3\u8154\u5185\u7ba1\u7406\u30fb\u6839\u7ba1\u6cbb\u7642\u30fb\u6b6f\u5468\u75c5\u7ba1\u7406\u30fb\u304a\u53e3\u306e\u76f8\u8ac7\uff09WEB\u4e88\u7d04\u306f\u3053\u3061\u3089<a href=\"http:\/\/www.gomidental-kashiwa.com\/reservation\/\" target=\"_blank\" rel=\"noopener\" title=\"\">http:\/\/www.gomidental-kashiwa.com\/reservation\/<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udcde \u304a\u96fb\u8a71\u3067\u306e\u3054\u4e88\u7d04\u30fb\u304a\u554f\u3044\u5408\u308f\u305b\uff08\u5065\u5eb7\u8a3a\u65ad\u30fb\u30ef\u30af\u30c1\u30f3\u306a\u3069\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3010\u533b\u79d1\u3011\uff1a04-7196-7531 \u3010\u6b6f\u79d1\u3011\uff1a04-7191-7081<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83c\udfe5 \u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af \u30a2\u30af\u30bb\u30b9 \u3012277-0902 \u5343\u8449\u770c\u67cf\u5e02\u5927\u4e95764-1 \u30d0\u30b9\u3067\u304a\u8d8a\u3057\u306e\u65b9\uff1a\u5343\u4ee3\u7530\u5e38\u78d0\u7dda \u67cf\u99c5\u6771\u53e3 \u6771\u6b66\u30d0\u30b91\u756a\u4e57\u5834\uff08\u300c\u6cbc\u5357\u8eca\u5eab\u300d\u300c\u5c0f\u91ce\u585a\u53f0\u300d\u300c\u624b\u8cc0\u306e\u4e18\u516c\u5712\u300d\u300c\u5e03\u702c\u300d\u884c\u304d\uff09\u3088\u308a\u30d0\u30b915\u5206 \u300c\u5927\u4e95\u300d\u4e0b\u8eca \u5f92\u6b691\u5206 \u8eca\u3067\u304a\u8d8a\u3057\u306e\u65b9\uff1a\u67cf\u99c5\u3088\u308a\u7d0415\u5206<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-478.jpg\" alt=\"\" class=\"wp-image-6902\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-478.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-478-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-479.jpg\" alt=\"\" class=\"wp-image-6903\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-479.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-479-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-480.jpg\" alt=\"\" class=\"wp-image-6904\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-480.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-480-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-481.jpg\" alt=\"\" class=\"wp-image-6905\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-481.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-481-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-482.jpg\" alt=\"\" class=\"wp-image-6906\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-482.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-482-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-483.jpg\" alt=\"\" class=\"wp-image-6907\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-483.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-483-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-484.jpg\" alt=\"\" class=\"wp-image-6908\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-484.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-484-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-485.jpg\" alt=\"\" class=\"wp-image-6909\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-485.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-485-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-486.jpg\" alt=\"\" class=\"wp-image-6910\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-486.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-486-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-487.jpg\" alt=\"\" class=\"wp-image-6911\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-487.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-487-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-488.jpg\" alt=\"\" class=\"wp-image-6912\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-488.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-488-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-489.jpg\" alt=\"\" class=\"wp-image-6913\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-489.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-489-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-490.jpg\" alt=\"\" class=\"wp-image-6914\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-490.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-490-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-491.jpg\" alt=\"\" class=\"wp-image-6915\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-491.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-491-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-492.jpg\" alt=\"\" class=\"wp-image-6916\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-492.jpg 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/07\/image-492-400x224.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Laux L, Sullivan J, Perry MS, et al. &#8220;Zorevunersen in Children and Adolescents with Dravet Syndrome.&#8221; <em>New England Journal of Medicine<\/em>. 2026; 394: 969-982.<\/p>\n<\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\">\u25a0\u95a2\u9023\u8a18\u4e8b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1. \u907a\u4f1d\u5b50\u306e\u30a8\u30e9\u30fc\u3092\u300c\u85ac\u300d\u3067\u76f4\u63a5\u4fee\u7406\u3059\u308b\u6700\u65b0\u6cbb\u7642\u306b\u8208\u5473\u304c\u3042\u308b\u65b9\u3078<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u30c9\u30e9\u30d9\u75c7\u5019\u7fa4\u306e\u3088\u3046\u306b\u3001\u7279\u5b9a\u306e\u300c\u907a\u4f1d\u5b50\u306e\u30a8\u30e9\u30fc\u300d\u3092\u30d4\u30f3\u30dd\u30a4\u30f3\u30c8\u3067\u72d9\u3044\u6483\u3061\u306b\u3059\u308b\u85ac\u306e\u958b\u767a\u306f\u3001\u304c\u3093\u6cbb\u7642\u306e\u5206\u91ce\u3067\u3082\u5287\u7684\u306a\u9032\u6b69\u3092\u9042\u3052\u3066\u3044\u307e\u3059\u3002\u304c\u3093\u7d30\u80de\u304c\u52dd\u624b\u306b\u5897\u6b96\u3059\u308b\u539f\u56e0\u3068\u306a\u308b\u300c\u58ca\u308c\u305f\u30d6\u30ec\u30fc\u30ad\u907a\u4f1d\u5b50\uff08p53\uff09\u300d\u3092\u518d\u6d3b\u6027\u5316\u3055\u305b\u3001\u304c\u3093\u7d30\u80de\u3092\u81ea\u6ec5\u306b\u5c0e\u304f\u6700\u5148\u7aef\u306e\u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30fb\u30e1\u30c7\u30a3\u30b7\u30f3\uff08\u500b\u5225\u5316\u533b\u7642\uff09\u306e\u4ed5\u7d44\u307f\u306b\u3064\u3044\u3066\u5c02\u9580\u533b\u304c\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-wp-embed\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"58TgoZyShZ\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-6761\/\">TP53 Y220C\u5909\u7570\u816b\u760d\u306b\u5bfe\u3059\u308bp53\u518d\u6d3b\u6027\u5316\u85ac\u300c\u30ec\u30b6\u30bf\u30dd\u30d7\u30c8\uff08rezatapopt\uff09\u300d\u306e\u7b2c1\u76f8\u8a66\u9a13\uff08PYNNACLE\u8a66\u9a13\uff09\u306b\u3064\u3044\u3066\u67cf\u6211\u5b6b\u5b50\u306e\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u304c\u89e3\u8aac<\/a><\/blockquote><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; visibility: hidden;\" title=\"\u201cTP53 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class=\"wp-block-paragraph\">\u3066\u3093\u304b\u3093\u306a\u3069\u306e\u795e\u7d4c\u75be\u60a3\u3084\u514d\u75ab\u7cfb\u306e\u6301\u75c5\u304c\u3042\u308b\u65b9\u306f\u3001\u80ba\u708e\u306a\u3069\u306e\u611f\u67d3\u75c7\u3092\u304d\u3063\u304b\u3051\u306b\u5168\u8eab\u72b6\u614b\u304c\u6025\u6fc0\u306b\u60aa\u5316\uff08\u767a\u4f5c\u306e\u8a98\u767a\u306a\u3069\uff09\u3059\u308b\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002\u30a6\u30a4\u30eb\u30b9\u3084\u7d30\u83cc\u304b\u3089\u4f53\u3092\u5f37\u529b\u306b\u5b88\u308a\u629c\u304f\u305f\u3081\u306e\u300c\u80ba\u708e\u7403\u83cc\u30ef\u30af\u30c1\u30f3\u300d\u306e\u4ed5\u7d44\u307f\u3068\u3001\u5f53\u9662\u304c\u63d0\u6848\u3059\u308b\u6700\u9069\u306a\u63a5\u7a2e\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u306b\u3064\u3044\u3066\u3054\u6848\u5185\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-wp-embed\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"m6nQXhKV8D\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-4703\/\">\u30102026\u5e74\u5ea6\u7248\u3011\u67cf\u30fb\u6211\u5b6b\u5b50\u3067\u9078\u3076\u80ba\u708e\u7403\u83cc\u30ef\u30af\u30c1\u30f3\uff1a\u516c\u8cbb\u306e\u300c\u30d7\u30ec\u30d9\u30ca\u30fc20\u300d\u3068\u6700\u65b0\u306e\u300c\u30ad\u30e3\u30c3\u30d7\u30d0\u30c3\u30af\u30b921\u300d\u3092\u4f7f\u3044\u5206\u3051\u308b\u6700\u5f37\u306e\u4e88\u9632\u6226\u7565<\/a><\/blockquote><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; visibility: hidden;\" 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class=\"wp-block-embed is-type-wp-embed\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"E9goYt6BON\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-5215\/\">\u3010\u67cf\u6211\u5b6b\u5b50\u5e02\u30fb\u533b\u79d1\u6b6f\u79d1\u9023\u643a\u3011\u6025\u5897\u3059\u308b\u300c\u30c9\u30e9\u30a4\u30de\u30a6\u30b9\uff08\u53e3\u8154\u4e7e\u71e5\u75c7\uff09\u300d\u306e\u610f\u5916\u306a\u539f\u56e0\uff1a\u53e3\u81ed\u30fb\u3080\u3057\u6b6f\u3092\u9632\u304e\u3001\u5168\u8eab\u3092\u5b88\u308b\u553e\u6db2\u306e\u529b\uff5e\u6839\u7ba1\u6cbb\u7642\u5c02\u9580\u533b\u304c\u89e3\u8aac<\/a><\/blockquote><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; visibility: hidden;\" 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