{"id":8174,"date":"2026-08-30T21:44:56","date_gmt":"2026-08-30T12:44:56","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=8174"},"modified":"2026-08-30T21:44:56","modified_gmt":"2026-08-30T12:44:56","slug":"post-8174","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-8174\/","title":{"rendered":"\u907a\u4f1d\u6027\u6eb6\u8840\u6027\u8ca7\u8840\u306e\u4ee3\u8b1d\u6539\u5584\u3068\u65b0\u305f\u306a\u6cbb\u7642\u6226\u7565\uff1a\u30d4\u30eb\u30d3\u30f3\u9178\u30ad\u30ca\u30fc\u30bc\uff08PK\uff09\u6d3b\u6027\u5316\u85ac\u3002Lancet2026\u3002"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u6301\u305f\u306a\u3044\u8d64\u8840\u7403\u306e\u5bbf\u547d\u3002\u5acc\u6c17\u6027\u89e3\u7cd6\u7cfb\u306e\u8981\u300cPKR\u300d\u3092\u30a2\u30ed\u30b9\u30c6\u30ea\u30c3\u30af\u306b\u6d3b\u6027\u5316\u3057\u3001ATP\u67af\u6e07\u30fb\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u30fb\u5909\u5f62\u80fd\u4f4e\u4e0b\u306e\u9023\u9396\u3092\u65ad\u3061\u5207\u308b\u4f53\u306e\u4ed5\u7d44\u307f<\/strong><\/h2>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u3057\u304b\u3057\u8fd1\u5e74\u3001\u4e00\u6b21\u7684\u306a\u907a\u4f1d\u5b50\u5909\u7570\u306e\u67a0\u3092\u8d85\u3048\u3066\u3001\u300c\u8d64\u8840\u7403\u306e\u4ee3\u8b1d\u969c\u5bb3\uff08ATP\u306e\u76f8\u5bfe\u7684\u67af\u6e07\uff09\u300d\u304c\u69d8\u3005\u306a\u6eb6\u8840\u6027\u8ca7\u8840\u306b\u5171\u901a\u3057\u3066\u4ecb\u5728\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u4e16\u754c\u6700\u9ad8\u5cf0\u306e\u533b\u5b66\u8a8c\u300eThe Lancet\u300f\u306b\u767a\u8868\u3055\u308c\u305f\u5305\u62ec\u7684\u30ec\u30d3\u30e5\u30fc\u8ad6\u6587\uff082026\u5e744\u6708\u53f7\uff09\u306f\u3001\u8d64\u8840\u7403\u306e\u89e3\u7cd6\u7cfb\u6700\u7d42\u6bb5\u968e\u3092\u53f8\u308b\u9175\u7d20\u3092\u76f4\u63a5\u6d3b\u6027\u5316\u3059\u308b\u300c\u30d4\u30eb\u30d3\u30f3\u9178\u30ad\u30ca\u30fc\u30bc\uff08PK\uff09\u6d3b\u6027\u5316\u85ac\u300d\u304c\u3001\u8d64\u8840\u7403\u306e\u751f\u5b58\u3068\u6a5f\u80fd\u7dad\u6301\u3092\u6839\u5e95\u304b\u3089\u652f\u3048\u308b\u4f5c\u7528\u6a5f\u5e8f\u3068\u3001\u305d\u306e\u81e8\u5e8a\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u4f53\u7cfb\u7684\u306b\u89e3\u8aac\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1. \u8d64\u8840\u7403\u306e\u751f\u5b58\u3092\u63e1\u308b\u89e3\u7cd6\u7cfb\u3068\u3001ATP\u6b20\u4e4f\u304c\u62db\u304f\u300c\u6eb6\u8840\u306e\u9023\u9396\u300d\uff08\u4f53\u306e\u4ed5\u7d44\u307f\uff09<\/strong> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6210\u719f\u3057\u305f\u8d64\u8840\u7403\u306b\u306f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u304c\u5b58\u5728\u305b\u305a\u3001\u597d\u6c17\u6027\u547c\u5438\uff08\u9178\u7d20\u3092\u7528\u3044\u305fATP\u7523\u751f\uff09\u3092\u884c\u3046\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\u3002\u305d\u306e\u305f\u3081\u3001\u7d30\u80de\u306e\u751f\u547d\u7dad\u6301\u306b\u5fc5\u8981\u306a\u3059\u3079\u3066\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\uff08ATP\uff09\u3092\u3001\u7d30\u80de\u8cea\u306b\u304a\u3051\u308b\u300c\u5acc\u6c17\u6027\u89e3\u7cd6\u7cfb\uff08\u30a8\u30e0\u30c7\u30f3\u30fb\u30de\u30a4\u30e4\u30fc\u30db\u30d5\u7d4c\u8def\uff09\u300d\u306e\u307f\u306b\u4f9d\u5b58\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u89e3\u7cd6\u7cfb\u306e\u6700\u7d42\u6bb5\u968e\u3067\u4e0d\u53ef\u9006\u7684\u306bATP\u3092\u7523\u751f\u3059\u308b\u5f8b\u901f\u9175\u7d20\u304c\u3001\u8d64\u8840\u7403\u7279\u7570\u7684\u30a2\u30a4\u30bd\u30b6\u30a4\u30e0\u3067\u3042\u308b\u300c\u30d4\u30eb\u30d3\u30f3\u9178\u30ad\u30ca\u30fc\u30bcR\uff08PKR\uff09\u300d\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8d64\u8840\u7403\u5185\u306eATP\u304c\u4e0d\u8db3\u3059\u308b\u3068\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5bc6\u63a5\u306b\u9023\u52d5\u3057\u305f\u591a\u9762\u7684\u306a\u6a5f\u80fd\u969c\u5bb3\u304c\u5f15\u304d\u8d77\u3053\u3055\u308c\u3001\u65e9\u671f\u6eb6\u8840\u3078\u3068\u76f4\u7d50\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u84c4\u7a4d<\/strong>\uff1a\u30b0\u30eb\u30b3\u30fc\u30b9\u306e\u30ea\u30f3\u9178\u5316\u304c\u969c\u5bb3\u3055\u308c\u308b\u3068\u3001\u30da\u30f3\u30c8\u30fc\u30b9\u30ea\u30f3\u9178\u7d4c\u8def\uff08HMP\uff09\u3078\u306e\u70ad\u7d20\u4f9b\u7d66\u304c\u6e1b\u5c11\u3057\u3001\u6297\u9178\u5316\u7269\u8cea\u30b0\u30eb\u30bf\u30c1\u30aa\u30f3\u306e\u9084\u5143\u306b\u5fc5\u8981\u306aNADPH\u304c\u67af\u6e07\u3057\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u308b\u819c\u9aa8\u683c\u306e\u5909\u6027\u304c\u52a0\u901f\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u819c\u5909\u5f62\u80fd\u306e\u4f4e\u4e0b\u3068\u8131\u6c34<\/strong>\uff1aATP\u4f9d\u5b58\u6027\u30ea\u30f3\u9178\u5316\u306e\u4f4e\u4e0b\u306b\u3088\u308a\u819c\u9aa8\u683c\uff08Band 3\u3084\u30d7\u30ed\u30c6\u30a4\u30f34.1R\uff09\u306e\u76f8\u4e92\u4f5c\u7528\u304c\u4e71\u308c\u3001\u819c\u306e\u67d4\u8edf\u6027\u304c\u5931\u308f\u308c\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u7d30\u80de\u819c\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u30dd\u30f3\u30d7\uff08Ca\u00b2\u207a-ATPase\uff09\u306e\u6a5f\u80fd\u304c\u843d\u3061\u3066\u7d30\u80de\u5185\u30ab\u30eb\u30b7\u30a6\u30e0\u6fc3\u5ea6\u304c\u4e0a\u6607\u3059\u308b\u3068\u3001Gardos\u30c1\u30e3\u30cd\u30eb\uff08\u30ab\u30eb\u30b7\u30a6\u30e0\u611f\u53d7\u6027K\u207a\u30c1\u30e3\u30cd\u30eb\uff09\u304c\u958b\u304d\u3001\u7d30\u80de\u5916\u3078\u306e\u30ab\u30ea\u30a6\u30e0\u3068\u6c34\u5206\u306e\u55aa\u5931\uff08\u7d30\u80de\u8131\u6c34\uff09\u304c\u9032\u884c\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u819c\u975e\u5bfe\u79f0\u6027\u306e\u7834\u7dbb<\/strong>\uff1aATP\u4e0d\u8db3\u306b\u3088\u3063\u3066\u30d5\u30ea\u30c3\u30d1\u30fc\u30bc\u6d3b\u6027\u304c\u4f4e\u4e0b\u3057\u30b9\u30af\u30e9\u30f3\u30d6\u30e9\u30fc\u30bc\u304c\u6d3b\u6027\u5316\u3059\u308b\u3068\u3001\u901a\u5e38\u306f\u819c\u5185\u5074\u306b\u7dad\u6301\u3055\u308c\u3066\u3044\u308b\u30db\u30b9\u30d5\u30a1\u30c1\u30b8\u30eb\u30bb\u30ea\u30f3\uff08PS\uff09\u304c\u5916\u5074\u306b\u9732\u51fa\u3057\u307e\u3059\u3002\u3053\u308c\u304c\u76ee\u5370\u3068\u306a\u308a\u3001\u813e\u81d3\u306e\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u8caa\u98df\u30fb\u7834\u58ca\u3055\u308c\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u7121\u52b9\u9020\u8840<\/strong>\uff1a\u8d64\u82bd\u7403\u306e\u6210\u719f\u904e\u7a0b\u306b\u304a\u3051\u308b\u30a8\u30cd\u30eb\u30ae\u30fc\u4e0d\u5168\u3084\u6297\u9178\u5316\u80fd\u4f4e\u4e0b\u306b\u3088\u308a\u3001\u9aa8\u9ac4\u5185\u3067\u306e\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff08\u7121\u52b9\u9020\u8840\uff09\u304c\u8a98\u767a\u3055\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2. \u30a2\u30ed\u30b9\u30c6\u30ea\u30c3\u30af\u6d3b\u6027\u5316\u306b\u3088\u308b\u4ee3\u8b1d\u6539\u5584\u3068\u30c7\u30e5\u30a2\u30eb\u30a2\u30af\u30b7\u30e7\u30f3\uff08\u85ac\u7406\u6a5f\u5e8f\uff09<\/strong> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d4\u30eb\u30d3\u30f3\u9178\u30ad\u30ca\u30fc\u30bc\u6d3b\u6027\u5316\u85ac\uff08\u4ee3\u8868\u85ac\uff1a\u30df\u30bf\u30d4\u30d0\u30c3\u30c8 [mitapivat]\u3001\u30a8\u30bf\u30dc\u30d4\u30d0\u30c3\u30c8 [etavopivat]\u3001\u30c6\u30d0\u30d4\u30d0\u30c3\u30c8 [tebapivat]\uff09\u306f\u3001PKR\u9175\u7d20\u306e\u4e8c\u91cf\u4f53\u754c\u9762\u306b\u3042\u308b\u7d50\u5408\u90e8\u4f4d\u306b\u30a2\u30ed\u30b9\u30c6\u30ea\u30c3\u30af\u306b\u7d50\u5408\u3057\u3001\u9175\u7d20\u69cb\u9020\u3092\u4e0d\u6d3b\u6027\u306aT\u72b6\u614b\uff08tense\uff09\u304b\u3089\u9ad8\u6d3b\u6027\u306aR\u72b6\u614b\uff08relaxed\uff09\u3078\u3068\u9077\u79fb\u3055\u305b\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u57fa\u8cea\u89aa\u548c\u6027\u304c\u98db\u8e8d\u7684\u306b\u9ad8\u307e\u308a\u3001\u89e3\u7cd6\u7cfb\u306e\u6d41\u901f\uff08\u30b0\u30ea\u30b3\u30ea\u30c6\u30a3\u30c3\u30af\u30fb\u30d5\u30e9\u30c3\u30af\u30b9\uff09\u304c\u4ea2\u9032\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\"><strong>\u25a1\u30af\u30ea\u30cb\u30c3\u30af\u304b\u3089\u306e\u30e1\u30c3\u30bb\u30fc\u30b8<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u3001\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u30fb\u30ea\u30a6\u30de\u30c1\u81a0\u539f\u75c5\u5c02\u9580\u533b\u3001\u304a\u3088\u3073\u809d\u81d3\u5c02\u9580\u533b\u304c\u5728\u7c4d\u3057\u3001\u65e5\u3005\u52c9\u5b66\u306b\u52aa\u3081\u308b\u3053\u3068\u3067\u6b63\u78ba\u306a\u8a3a\u65ad\u30fb\u6cbb\u7642\u3092\u884c\u3048\u308b\u3088\u3046\u52aa\u529b\u3092\u7a4d\u307f\u91cd\u306d\u3066\u3044\u307e\u3059\u3002\u60a3\u8005\u69d8\u306e\u8a34\u3048\u304c\u3001\u3069\u306e\u3088\u3046\u306a\u300c\u4f53\u306e\u4ed5\u7d44\u307f\u300d\u3067\u8d77\u304d\u3066\u3044\u308b\u306e\u304b\u3092\u3001\u8eab\u4f53\u8a3a\u5bdf\u3001\u7dbf\u5bc6\u306a\u8840\u6db2\u691c\u67fb\u3084\u8d85\u97f3\u6ce2\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30fb\u5fc5\u8981\u306b\u5fdc\u3058\u3066CT\u7b49\u304b\u3089\u8ad6\u7406\u7684\u306b\u89e3\u304d\u660e\u304b\u3057\u3001\u6b63\u78ba\u306a\u8a3a\u65ad\u306a\u3089\u3073\u306b\u5b89\u5168\u306a\u6cbb\u7642\u7ba1\u7406\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u3054\u63d0\u6848\u3057\u307e\u3059\u3002\u5f53\u9662\u306e\u5185\u79d1\u30fb\u767a\u71b1\u5916\u6765\u306f\u571f\u66dc\u65e5\u306e\u5348\u5f8c\u308217\u6642\u307e\u3067\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u3001\u5e73\u65e5\u304a\u5fd9\u3057\u304f\u3066\u7cbe\u5bc6\u306a\u5065\u5eb7\u7ba1\u7406\u3084\u691c\u67fb\u306b\u306a\u304b\u306a\u304b\u901a\u3048\u306a\u3044\u60a3\u8005\u69d8\u3067\u3082\u3001\u9031\u672b\u306b\u3086\u3068\u308a\u3092\u6301\u3063\u3066\u5c02\u9580\u533b\u306b\u3088\u308b\u304d\u3081\u7d30\u304b\u306a\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u3092\u53d7\u3051\u3066\u3044\u305f\u3060\u304f\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u611f\u67d3\u75c7\u3092\u4e88\u9632\u30fb\u7ba1\u7406\u3059\u308b\u4e0a\u3067\u3001\u304a\u53e3\u306e\u4e2d\u306e\u885b\u751f\u7ba1\u7406\uff08\u6b6f\u79d1\u7ba1\u7406\uff09\u306f\u3001\u898b\u904e\u3054\u3055\u308c\u304c\u3061\u3067\u3059\u304c\u6975\u3081\u3066\u91cd\u8981\u306a\u300c\u9632\u885b\u30e9\u30a4\u30f3\u300d\u3067\u3059\u3002\u304a\u53e3\u306e\u4e2d\u306b\u91cd\u5ea6\u306e\u6b6f\u5468\u75c5\uff08\u6162\u6027\u708e\u75c7\uff09\u304c\u5b58\u5728\u3057\u3066\u3044\u308b\u3068\u3001\u98df\u4e8b\u306e\u969b\u306e\u5480\u56bc\uff08\u565b\u3080\u3053\u3068\uff09\u3084\u6bce\u65e5\u306e\u30cf\u30df\u30ac\u30ad\u3068\u3044\u3063\u305f\u4e9b\u7d30\u306a\u523a\u6fc0\u306b\u3088\u3063\u3066\u3001\u6b6f\u5468\u30dd\u30b1\u30c3\u30c8\u306e\u8840\u7ba1\u304b\u3089\u5927\u91cf\u306e\u53e3\u8154\u5185\u7d30\u83cc\u304c\u5bb9\u6613\u306b\u8840\u6db2\u4e2d\u306b\u4fb5\u5165\u3057\u307e\u3059\uff08\u4e00\u904e\u6027\u83cc\u8840\u75c7\uff09\u3002\u5065\u5eb7\u306a\u72b6\u614b\u3067\u3042\u308c\u3070\u514d\u75ab\u306b\u3088\u3063\u3066\u6392\u9664\u3055\u308c\u307e\u3059\u304c\u3001\u6eb6\u8840\u6027\u8ca7\u8840\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u8840\u6db2\u75be\u60a3\u3001\u9244\u904e\u5270\u3084\u813e\u6458\u5f8c\u306e\u65b9\u3001\u3042\u308b\u3044\u306f\u7cd6\u5c3f\u75c5\u306a\u3069\u306e\u6301\u75c5\u3092\u304a\u6301\u3061\u306e\u65b9\u3084\u9ad8\u9f62\u306e\u60a3\u8005\u69d8\u306a\u3069\u306e\u69cb\u9020\u7684\u306a\u5f31\u70b9\uff08\u57fa\u8cea\uff09\u304c\u3042\u308b\u72b6\u614b\u3067\u306f\u3001\u8840\u6db2\u306b\u4e57\u3063\u3066\u6d41\u308c\u3066\u304d\u305f\u304a\u53e3\u306e\u7d30\u83cc\u304c\u809d\u81d3\u3084\u5fc3\u81d3\u306e\u5f01\u3001\u4eba\u5de5\u95a2\u7bc0\u306a\u3069\u306b\u5b9a\u7740\u3057\u3001\u91cd\u75c7\u306e\u5316\u81bf\u6027\u611f\u67d3\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059\u76f4\u63a5\u306e\u5f15\u304d\u91d1\uff08\u539f\u56e0\u7d4c\u8def\uff09\u3068\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u5f53\u9662\u306e\u6b6f\u79d1\u306f\u571f\u66dc\u65e5\u5348\u5f8c2\u6642\uff0814\u6642\uff09\u307e\u3067\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u3001\u533b\u79d1\u3068\u6b6f\u79d1\u304c\u7dca\u5bc6\u306b\u9023\u643a\u3059\u308b\u300c\u533b\u79d1\u6b6f\u79d1\u9023\u643a\u6cbb\u7642\u300d\u306e\u5f37\u307f\u3092\u6d3b\u304b\u3057\u3001\u5185\u79d1\u3067\u306e\u5168\u8eab\u7ba1\u7406\u3068\u9023\u52d5\u3057\u306a\u304c\u3089\u3001\u30d7\u30ed\u306b\u3088\u308b\u5fb9\u5e95\u7684\u306a\u304a\u53e3\u306e\u6e05\u6383\uff08PMTC\u306b\u3088\u308b\u30d0\u30a4\u30aa\u30d5\u30a3\u30eb\u30e0\u9664\u53bb\uff09\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002\u4f53\u5168\u4f53\u306e\u5165\u308a\u53e3\u3067\u3042\u308b\u304a\u53e3\u306e\u7d30\u83cc\u3092\u304d\u308c\u3044\u306b\u30ea\u30bb\u30c3\u30c8\u3059\u308b\u3053\u3068\u3067\u3001\u5185\u79d1\u6cbb\u7642\u306e\u5b89\u5168\u6027\u3092\u98db\u8e8d\u7684\u306b\u9ad8\u3081\u3001\u751f\u6daf\u306b\u308f\u305f\u308b\u304a\u4f53\u306e\u5065\u5eb7\u3092\u30c8\u30fc\u30bf\u30eb\u3067\u652f\u3048\u629c\u304d\u307e\u3059\u3002\u67cf\u30fb\u6211\u5b6b\u5b50\u30a8\u30ea\u30a2\u3067\u539f\u56e0\u4e0d\u660e\u306e\u3060\u308b\u3055\u3084\u98df\u6b32\u4f4e\u4e0b\u3001\u304a\u53e3\u306e\u4e7e\u304d\u3084\u30c8\u30e9\u30d6\u30eb\u306b\u304a\u60a9\u307f\u306e\u65b9\u306f\u3001\u304a\u6c17\u8efd\u306b\u5f53\u9662\u307e\u3067\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u25a0\u53d7\u8a3a\u3092\u3054\u5e0c\u671b\u306e\u65b9\u3078<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udc49 <strong>\u3010\u533b\u79d1\u3011\uff08\u30a2\u30ec\u30eb\u30ae\u30fc\u81a0\u539f\u75c5\u30ea\u30a6\u30de\u30c1\u5185\u79d1\u30fb\u7dcf\u5408\u5185\u79d1\u30fb\u767a\u71b1\u5916\u6765\u30fb\u3060\u308b\u3055\u3084\u8ca7\u8840\u30fb\u8840\u6db2\u75be\u60a3\u306e\u76f8\u8ac7\u306a\u3069\uff09WEB\u4e88\u7d04\u306f\u3053\u3061\u3089<\/strong> \u203b\u5f53\u9662\u306e\u5185\u79d1\u30fb\u767a\u71b1\u5916\u6765\u306f\u3001\u571f\u66dc\u65e5\u5348\u5f8c\u308217\u6642\u307e\u3067\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002<a href=\"https:\/\/melmo-app.com\/clinic\/673d5e08785f0f0030870bdb\/reservation?method=visit\" target=\"_blank\" rel=\"noopener\"> https:\/\/melmo-app.com\/clinic\/673d5e08785f0f0030870bdb\/reservation?method=visit<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udc49 <strong>\u3010\u6b6f\u79d1\u3011\uff08\u6839\u7ba1\u6cbb\u7642\u30fb\u3080\u3057\u6b6f\u30fb\u6b6f\u5468\u75c5\u30fb\u30d7\u30ed\u306b\u3088\u308b\u53e3\u8154\u30b1\u30a2\u30fb\u611f\u67d3\u4e88\u9632\u6b6f\u79d1\u30fb\u4e00\u822c\u6b6f\u79d1\u306a\u3069\uff09WEB\u4e88\u7d04\u306f\u3053\u3061\u3089<\/strong> \u203b\u5f53\u9662\u306e\u6b6f\u79d1\u306f\u3001\u571f\u66dc\u65e5\u5348\u5f8c2\u6642\uff0814\u6642\uff09\u307e\u3067\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002 <a href=\"http:\/\/www.gomidental-kashiwa.com\/reservation\/\" target=\"_blank\" rel=\"noopener\">http:\/\/www.gomidental-kashiwa.com\/reservation\/<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udcde <strong>\u304a\u96fb\u8a71\u3067\u306e\u3054\u4e88\u7d04\u30fb\u304a\u554f\u3044\u5408\u308f\u305b\uff08\u304a\u85ac\u306e\u76f8\u8ac7\u30fb\u5065\u5eb7\u8a3a\u65ad\u30fb\u30ef\u30af\u30c1\u30f3\u306a\u3069\uff09<\/strong> \u3010\u533b\u79d1\u3011\uff1a04-7196-7531 \u3010\u6b6f\u79d1\u3011\uff1a04-7191-7081<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83c\udfe5 <strong>\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af \u30a2\u30af\u30bb\u30b9<\/strong> \u3012277-0902 \u5343\u8449\u770c\u67cf\u5e02\u5927\u4e95764-1\uff08\u5927\u4e95\u4ea4\u5dee\u70b9\u8fd1\u304f\u3001\u99d0\u8eca\u5834\u5b8c\u5099\uff09 \u30d0\u30b9\u3067\u304a\u8d8a\u3057\u306e\u65b9\uff1a\u5343\u4ee3\u7530\u5e38\u78d0\u7dda \u67cf\u99c5\u6771\u53e3 \u6771\u6b66\u30d0\u30b91\u756a\u4e57\u5834\uff08\u300c\u6cbc\u5357\u8eca\u5eab\u300d\u300c\u5c0f\u91ce\u585a\u53f0\u300d\u300c\u624b\u8cc0\u306e\u4e18\u516c\u5712\u300d\u300c\u5e03\u702c\u300d\u884c\u304d\uff09\u3088\u308a\u30d0\u30b915\u5206 \u300c\u5927\u4e95\u300d\u4e0b\u8eca \u5f92\u6b691\u5206 \u8eca\u3067\u304a\u8d8a\u3057\u306e\u65b9\uff1a\u67cf\u99c5\u3088\u308a\u7d0415\u5206<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-441.png\" alt=\"\" class=\"wp-image-8175\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-441.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-441-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-441-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-442.png\" alt=\"\" class=\"wp-image-8176\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-442.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-442-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-442-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-443.png\" alt=\"\" class=\"wp-image-8177\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-443.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-443-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-443-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-444.png\" alt=\"\" class=\"wp-image-8178\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-444.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-444-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-444-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-445.png\" alt=\"\" class=\"wp-image-8179\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-445.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-445-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-445-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-446.png\" alt=\"\" class=\"wp-image-8180\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-446.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-446-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-446-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-447.png\" alt=\"\" class=\"wp-image-8181\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-447.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-447-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-447-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-448.png\" alt=\"\" class=\"wp-image-8182\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-448.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-448-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-448-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-449.png\" alt=\"\" class=\"wp-image-8183\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-449.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-449-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-449-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-450.png\" alt=\"\" class=\"wp-image-8184\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-450.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-450-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-450-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-451.png\" alt=\"\" class=\"wp-image-8185\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-451.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-451-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-451-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-452.png\" alt=\"\" class=\"wp-image-8186\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-452.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-452-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-452-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-453.png\" alt=\"\" class=\"wp-image-8187\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-453.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-453-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-453-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-454.png\" alt=\"\" class=\"wp-image-8188\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-454.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-454-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-454-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-455.png\" alt=\"\" class=\"wp-image-8189\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-455.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-455-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/image-455-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Thomas Doeven, Andreas Glenth\u00f8j, Rachael F. Grace, and Eduard J. van Beers. &#8220;Pyruvate kinase activators in hereditary haemolytic anaemias: current evidence and clinical potential.&#8221; The Lancet. 2026; 407(10534): 1383-1396.<\/p>\n<\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\">\u25a0\u95a2\u9023\u8a18\u4e8b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1. \u8ca7\u8840\u306e\u521d\u671f\u5fb4\u5019\u3084\u809d\u6a5f\u80fd\u30fb\u4ee3\u8b1d\u306e\u6570\u5024\u3092\u7db2\u7f85\u7684\u306b\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3057\u3001\u8eab\u4f53\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u5ba2\u89b3\u7684\u306b\u628a\u63e1\u3057\u305f\u3044\u65b9\u3078<\/strong><\/p>\n\n\n\n<p 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class=\"wp-block-embed is-type-wp-embed\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"IHl9d9Y360\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-7663\/\">\u300c\u8af8\u5203\u306e\u5263\u300d\u3092\u540d\u85ac\u306b\u5909\u3048\u308b\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u6cbb\u7642\u306e\u5b8c\u5168\u30ac\u30a4\u30c9\u3002\u52b9\u679c\u3068\u526f\u4f5c\u7528\u306e\u7406\u89e3\u3067\u5b89\u5168\u306a\u6cbb\u7642\u3092\u3002\u67cf\u6211\u5b6b\u5b50\u306e\u30ea\u30a6\u30de\u30c1\u5c02\u9580\u533b\u304c\u89e3\u8aac<\/a><\/blockquote><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; visibility: hidden;\" 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