{"id":8527,"date":"2026-09-06T16:39:05","date_gmt":"2026-09-06T07:39:05","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=8527"},"modified":"2026-09-06T16:39:06","modified_gmt":"2026-09-06T07:39:06","slug":"post-8527","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-8527\/","title":{"rendered":"\u300c\u9650\u5c40\u6027\u5f37\u76ae\u75c7\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32026\uff08\u7b2c2\u7248\uff09\u300d\u304c\u898f\u5b9a\u3059\u308b4\u5927\u5149\u7dda\u7642\u6cd5\uff08UVA1\u30fbPUVA\u30fbNB-UVB\u30fb\u30a8\u30ad\u30b7\u30de\uff09\u306e\u6cbb\u7642\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u3001\u79d1\u5b66\u7684\u306b\u7121\u52b9\u3068\u65ad\u5b9a\u3055\u308c\u305f\u300c5-ALA\u5c40\u6240\u5149\u7dda\u529b\u5b66\u7642\u6cd5\uff08PDT\uff09\u300d"},"content":{"rendered":"\n<h2 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class=\"wp-block-paragraph\">\u75c5\u5909\u304c\u6df1\u90e8\u7d44\u7e54\u306b\u53ca\u3076\u300c\u7dda\u72b6\u5f37\u76ae\u75c7\uff08linear scleroderma\uff09\u300d\u3084\u300c\u6c4e\u767a\u578b\uff08generalized morphea\uff09\u300d\u306b\u306f\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u3068\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u5168\u8eab\u4f75\u7528\u7642\u6cd5\uff08\u63a8\u5968\u5ea61B\uff09\u304c\u6a19\u6e96\u6cbb\u7642\u3068\u306a\u308a\u307e\u3059\u304c\u3001\u8868\u5728\u6027\u304b\u3064\u5c40\u6240\u7684\u306a\u300c\u6591\u72b6\u5f37\u76ae\u75c7\uff08circumscribed morphea\uff09\u300d\u306b\u304a\u3044\u3066\u306f\u3001\u5168\u8eab\u6027\u306e\u526f\u4f5c\u7528\u3092\u56de\u907f\u3057\u3064\u3064\u5c40\u6240\u306e\u6d3b\u52d5\u6027\u3092\u93ae\u3081\u308b\u300c\u5149\u7dda\u7642\u6cd5\uff08\u7269\u7406\u7642\u6cd5\uff09\u300d\u304c\u91cd\u8981\u306a\u6cbb\u7642\u306e\u9078\u629e\u80a2\u3068\u306a\u308a\u307e\u3059\u3002 2026\u5e749\u6708\u306b\u6539\u8a02\u516c\u8868\u3055\u308c\u305f\u65e5\u672c\u76ae\u819a\u79d1\u5b66\u4f1a\u306e\u300e\u9650\u5c40\u6027\u5f37\u76ae\u75c7\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32026\uff08\u7b2c2\u7248\uff09\u300f\u3067\u306f\u3001\u65e5\u5e38\u81e8\u5e8a\u3067\u7528\u3044\u3089\u308c\u308b\u5404\u7a2e\u5149\u7dda\u7642\u6cd5\u306e\u6709\u7528\u6027\u3092\u53b3\u683c\u306b\u518d\u8a55\u4fa1\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u304c\u3093\u6cbb\u7642\u306e\u5fdc\u7528\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u305f\u300c\u5c40\u6240\u5149\u7dda\u529b\u5b66\u7642\u6cd5\uff08PDT\uff09\u300d\u306b\u5bfe\u3059\u308b\u5f85\u671b\u306e\u5bfe\u7167\u8a66\u9a13\u7d50\u679c\u3092\u53cd\u6620\u3057\u3001\u4f55\u304c\u771f\u306b\u6709\u52b9\u3067\u3001\u4f55\u304c\u7121\u52b9\u306a\u306e\u304b\u3092EBM\uff08\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u304f\u533b\u7642\uff09\u306e\u5149\u306b\u3088\u3063\u3066\u51b7\u5fb9\u306b\u5cfb\u5225\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1. UVA1\u5149\u7dda\u7642\u6cd5\uff08\u63a8\u5968\u5ea6 2C\uff09\uff1aMMP-1\u3068IFN-\u03b3\u3092\u80fd\u52d5\u7684\u306b\u547c\u3073\u8d77\u3053\u3059\u300c\u7528\u91cf\u4f9d\u5b58\u7684\u300d\u6297\u7dda\u7dad\u5316\u4f5c\u7528<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u85ac\u7406\u30e1\u30ab\u30cb\u30ba\u30e0\uff08\u4f53\u306e\u4ed5\u7d44\u307f\uff09<\/strong>\uff1a \u9577\u6ce2\u9577\u7d2b\u5916\u7dda\u3067\u3042\u308bUVA1\uff08340\u301c400 nm\uff09\u306f\u3001\u7d2b\u5916\u7dda\u306e\u4e2d\u3067\u3082\u76ae\u819a\u306e\u6700\u3082\u6df1\u3044\u9818\u57df\uff08\u771f\u76ae\u6df1\u5c64\u304b\u3089\u76ae\u4e0b\u7d44\u7e54\u6d45\u5c64\uff09\u306b\u307e\u3067\u5230\u9054\u3059\u308b\u7269\u7406\u7684\u7279\u6027\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002 UVA1\u304c\u75c5\u5909\u90e8\u306b\u7167\u5c04\u3055\u308c\u308b\u3068\u3001\u5c40\u6240\u306e\u76ae\u819a\u7d44\u7e54\u306b\u304a\u3051\u308b\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u30e1\u30bf\u30ed\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc-1\uff08MMP-1\uff09\u304a\u3088\u3073\u30a4\u30f3\u30bf\u30fc\u30d5\u30a7\u30ed\u30f3\u03b3\uff08IFN-\u03b3\uff09\u306e\u7523\u751f\u304c\u5f37\u529b\u306b\u8a98\u767a\uff08\u5897\u52a0\uff09\u3055\u308c\u307e\u3059\u3002\u3053\u306eMMP-1\u304c\u3001\u7dda\u7dad\u5316\u3092\u5f62\u6210\u3057\u3066\u3044\u308b\u904e\u5270\u306a\u30b3\u30e9\u30fc\u30b2\u30f3\u675f\u3092\u76f4\u63a5\u5206\u89e3\u30fb\u878d\u89e3\u3059\u308b\u3068\u3068\u3082\u306b\u3001IFN-\u03b3\u304c\u7dda\u7dad\u5316\u306e\u5f37\u529b\u306a\u30a2\u30af\u30bb\u30eb\u3067\u3042\u308b\u300cTGF-\u03b2\u300d\u306e\u30b7\u30b0\u30ca\u30eb\u304a\u3088\u3073\u30b3\u30e9\u30fc\u30b2\u30f3\u7523\u751f\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u76f4\u63a5\u6291\u5236\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u81e8\u5e8a\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>\uff1a UVA1\u306e\u6cbb\u7642\u52b9\u679c\u306b\u304a\u3044\u3066\u6700\u3082\u91cd\u8981\u306a\u4e8b\u5b9f\u306f\u3001\u305d\u308c\u304c\u300c\u7528\u91cf\u4f9d\u5b58\u6027\uff08\u7167\u5c04\u30a8\u30cd\u30eb\u30ae\u30fc\u91cf\u306b\u6bd4\u4f8b\u3057\u3066\u52b9\u679c\u304c\u9ad8\u307e\u308b\uff09\u300d\u3067\u3042\u308b\u3068\u3044\u3046\u70b9\u3067\u3059\u3002Sator\u3089\u306b\u3088\u308b\u524d\u5411\u304d\u30aa\u30fc\u30d7\u30f3\u6bd4\u8f03\u5bfe\u7167\u8a66\u9a13\uff08RCT\uff09\u3067\u306f\u3001\u6d3b\u52d5\u6027\u76ae\u75b9\u3092\u6709\u3059\u308b\u60a3\u8005\u306b\u5bfe\u3057\u3001low-dose\uff0820 J\/cm\u00b2\uff09\u7fa4\u3001medium-dose\uff0870 J\/cm\u00b2\uff09\u7fa4\u3001\u975e\u7167\u5c04\u7fa4\u306b\u5206\u3051\u3066\u691c\u8a0e\u3057\u305f\u7d50\u679c\u3001\u8d85\u97f3\u6ce2\u306b\u3088\u308b\u8a55\u4fa1\u3067medium-dose\u7fa4\u306e\u307b\u3046\u304clow-dose\u7fa4\u3088\u308a\u3082\u771f\u76ae\u539a\u3092\u6709\u610f\u306b\u6539\u5584\u3055\u305b\u308b\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002\u307e\u305f\u3001Stege\u3089\u306b\u3088\u308bRCT\u3067\u3082\u3001high-dose\uff08130 J\/cm\u00b2\uff09\u7fa4\u306flow-dose\uff0820 J\/cm\u00b2\uff09\u7fa4\u3088\u308a\u3082\u6709\u610f\u306b\u9ad8\u3044\u6539\u5584\u52b9\u679c\u3092\u793a\u3057\u300110\u4f8b\u4e2d4\u4f8b\u3067\u76ae\u75b9\u304c\u5b8c\u5168\u306b\u6d88\u9000\u3057\u307e\u3057\u305f\u3002 \u3055\u3089\u306b\u3001Wang\u3089\u306e\u7814\u7a76\u3067\u306f\u3001\u65e5\u713c\u3051\uff08\u76ae\u819a\u306e\u9ed2\u8272\u5316\uff09\u304c\u9032\u3080\u3068\u3001UVA1\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u6291\u5236\u52b9\u679c\u3084MMP\u8a98\u5c0e\u52b9\u679c\u304c\u4f4e\u4e0b\uff08\u6e1b\u5f31\uff09\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u3092\u56de\u907f\u3059\u308b\u305f\u3081\u306b\u9023\u7d9a\u7167\u5c04\u3067\u306f\u306a\u304f\u300c\u30d1\u30eb\u30b9\u7167\u5c04\u300d\u306b\u3059\u3079\u304d\u3067\u3042\u308b\u3068\u3059\u308b\u3001\u5b9f\u8df5\u7684\u306a\u85ac\u7406\u52d5\u614b\u3082\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2. Broad-band-UVA\/PUVA\uff08\u63a8\u5968\u5ea6 2C\uff09\u304a\u3088\u3073 NB-UVB\uff08\u63a8\u5968\u5ea6 2C\uff09\u306e\u81e8\u5e8a\u7684\u7acb\u3061\u4f4d\u7f6e<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PUVA\u7642\u6cd5<\/strong>\uff1a Kerscher\u3089\u304c\u6700\u521d\u306b\u5831\u544a\u3057\u305fbath-PUVA\uff08\u30bd\u30e9\u30ec\u30f3\u6e29\u6d74\uff0bUVA\uff09\u3092\u306f\u3058\u3081\u3001\u5185\u670d\u30fb\u5916\u7528PUVA\u306f\u591a\u304f\u306e\u524d\u5411\u304d\u8a66\u9a13\u306b\u304a\u3044\u3066<strong>\u7d0480%\u4ee5\u4e0a\u306e\u9ad8\u3044\u76ae\u819a\u786c\u5316\u6539\u5584\u7387<\/strong>\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u5c0f\u5150\u9650\u5c40\u6027\u5f37\u76ae\u75c7\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u304a\u3044\u3066\u306f\u3001\u5168\u8eab\u514d\u75ab\u6291\u5236\u7642\u6cd5\u3067\u3042\u308b\u300c\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\uff08MTX\uff09\u30d7\u30ed\u30c8\u30b3\u30eb\u300d\u306e\u307b\u3046\u304cUVA\u7642\u6cd5\u5168\u822c\u3088\u308a\u3082\u6709\u610f\u306b\u512a\u308c\u305f\u6a5f\u80fd\u56de\u5fa9\u304a\u3088\u3073\u9032\u884c\u6291\u5236\u52b9\u679c\u3092\u793a\u3057\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u95a2\u7bc0\u62d8\u7e2e\u306a\u3069\u306e\u5408\u4f75\u75c7\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u4f8b\u3067\u306f\u5168\u8eab\u7642\u6cd5\u3092\u6700\u512a\u5148\u3059\u3079\u304d\u3067\u3042\u308b\u3053\u3068\u304c\u6559\u8a13\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>NB-UVB\u7642\u6cd5<\/strong>\uff1a Kreuter\u3089\u306b\u3088\u308bUVA1\u3068NB-UVB\u306e\u6bd4\u8f03RCT\uff0864\u4f8b\uff09\u306b\u304a\u3044\u3066\u3001NB-UVB\uff08\u30ca\u30ed\u30fc\u30d0\u30f3\u30c9UVB\uff09\u306fmedium-dose UVA1\u3088\u308a\u306f\u52b9\u679c\u304c\u30de\u30a4\u30eb\u30c9\u3067\u3042\u308b\u3082\u306e\u306e\u3001low-dose UVA1\u3068\u540c\u7b49\u306e\u6709\u610f\u306a\u7d44\u7e54\u5b66\u7684\u30fb\u8d85\u97f3\u6ce2\u5b66\u7684\u6539\u5584\u3092\u793a\u3057\u307e\u3057\u305f\u3002UVA1\u5c02\u7528\u7167\u5c04\u5668\u3092\u8a2d\u7f6e\u3057\u3066\u3044\u308b\u65bd\u8a2d\u304c\u56fd\u5185\u3067\u9650\u5b9a\u7684\u3067\u3042\u308b\u306e\u306b\u5bfe\u3057\u3001NB-UVB\u306f\u591a\u304f\u306e\u76ae\u819a\u79d1\u30af\u30ea\u30cb\u30c3\u30af\u306b\u666e\u53ca\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u300c\u5b9f\u7528\u6027\u306e\u9ad8\u3044\u4ee3\u66ff\u5149\u7dda\u7642\u6cd5\u300d\u3068\u3057\u3066\u6975\u3081\u3066\u6709\u7528\u306a\u9078\u629e\u80a2\u3068\u3057\u3066\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>3. \u96e3\u6cbb\u6027\u8868\u5728\u578b\uff08superficial morphea\uff09\u306b\u5bfe\u3059\u308b\u30a8\u30ad\u30b7\u30de\u30e9\u30a4\u30c8\uff08\u63a8\u5968\u5ea6 2C\uff09\u306e\u885d\u6483<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u81e8\u5e8a\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>\uff1a \u75c5\u5909\u304c\u771f\u76ae\u306e\u6975\u3081\u3066\u6d45\u3044\u9818\u57df\u306b\u9650\u5c40\u3059\u308b\u8868\u5728\u578b\uff08superficial morphea\uff09\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u3084\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\u5916\u7528\u304c\u7121\u52b9\u3067\u3042\u3063\u305f\u308a\u518d\u767a\u3092\u7e70\u308a\u8fd4\u3057\u305f\u308a\u3059\u308b\u300c\u6cbb\u7642\u62b5\u6297\u6027\u300d\u3092\u5448\u3057\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002 Mosbeh\u3089\u306b\u3088\u308b\u30aa\u30fc\u30d7\u30f3\u8a66\u9a13\uff0828\u4f8b\uff09\u3067\u306f\u3001\u3053\u308c\u3089\u5f93\u6765\u306e\u5916\u7528\u7642\u6cd5\u3084UVA1\u5149\u7dda\u7642\u6cd5\u304c\u7121\u52b9\u3001\u3042\u308b\u3044\u306f\u518d\u767a\u3057\u305f\u8868\u5728\u578b\u306b\u5bfe\u3057\u3001308 nm\u306e\u30e2\u30ce\u30af\u30ed\u30de\u30c6\u30a3\u30c3\u30af\u306a\u30a8\u30ad\u30b7\u30de\u30e9\u30a4\u30c8\u3092\u90312\u56de\u30016\u30f6\u6708\u9593\u7167\u5c04\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u306e\u60a3\u8005\u6e80\u8db3\u5ea6\u304c7.1%\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\uff0b\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\u5916\u7528\u304c23.1%\u3001UVA1\u304c5%\u306b\u3068\u3069\u307e\u3063\u305f\u306e\u306b\u5bfe\u3057\u3001\u30a8\u30ad\u30b7\u30de\u30e9\u30a4\u30c8\u3092\u7167\u5c04\u3055\u308c\u305f\u7fa4\u3067\u306f\u300c78.9%\u300d\u3068\u3044\u3046\u6975\u3081\u3066\u9ad8\u3044\u60a3\u8005\u6e80\u8db3\u5ea6\uff08\u6709\u610f\u306a\u76ae\u819a\u786c\u5316\u306e\u6539\u5584\uff09\u3092\u53e9\u304d\u51fa\u3057\u307e\u3057\u305f\u3002<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>4. 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\u30a2\u30df\u30ce\u30ec\u30d6\u30ea\u30f3\u9178\uff085-ALA\uff09\u306a\u3069\u306e\u5149\u611f\u53d7\u6027\u7269\u8cea\u3092\u76ae\u819a\u306b\u5857\u5e03\u3057\u305f\u5f8c\u306b\u7279\u5b9a\u306e\u53ef\u8996\u5149\u3092\u7167\u5c04\u3057\u3001\u751f\u3058\u308b\u6d3b\u6027\u9178\u7d20\uff08\u4e00\u91cd\u9805\u9178\u7d20\uff09\u306b\u3088\u3063\u3066\u7570\u5e38\u7d30\u80de\u3092\u6a19\u7684\u7834\u58ca\u3059\u308b\u5c40\u6240\u5149\u7dda\u529b\u5b66\u7642\u6cd5\uff08PDT\uff09\u306f\u3001\u4e00\u90e8\u306e\u75c7\u4f8b\u5831\u544a\u306b\u304a\u3044\u3066\u95a2\u7bc0\u53ef\u52d5\u57df\u306e\u5287\u7684\u306a\u6539\u5584\u306a\u3069\u304c\u5831\u544a\u3055\u308c\u3001\u7dda\u7dad\u5316\u6cbb\u7642\u306e\u65b0\u305f\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002 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6\u4f8b\uff09\u300d\u306b\u304a\u3044\u3066\u3001ALA-PDT\u306e\u51b7\u5fb9\u306a\u771f\u5b9f\u304c\u6d6e\u304d\u5f6b\u308a\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u672c\u8a66\u9a13\u306b\u304a\u3044\u3066\u30015-ALA\u30af\u30ea\u30fc\u30e0\u3092\u5857\u5e03\u3057\u3066\u5149\u7167\u5c04\u3092\u884c\u3063\u305f\u90e8\u4f4d\u3067\u306f\u3001\u6cbb\u7642\u7d42\u4e866\u9031\u9593\u5f8c\u306b\u6709\u610f\u306a\u76ae\u819a\u786c\u5316\u306e\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u540c\u6642\u306b\u300c\u304a\u85ac\u3092\u5857\u3089\u305a\u3001\u5149\u3082\u5f53\u3066\u3066\u3044\u306a\u3044\u975e\u7167\u5c04\u90e8\u4f4d\uff08\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\uff09\u300d\u3092\u8a73\u7d30\u306b\u89b3\u5bdf\u3057\u305f\u3068\u3053\u308d\u3001\u7167\u5c04\u90e8\u4f4d\u3068\u5168\u304f\u540c\u7b49\u306e\u76ae\u819a\u786c\u5316\u306e\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u305f\u306e\u3067\u3059\u3002\u3059\u306a\u308f\u3061\u3001PDT\u6cbb\u7642\u306b\u3088\u3063\u3066\u76ae\u819a\u304c\u67d4\u3089\u304b\u304f\u306a\u3063\u305f\u3088\u3046\u306b\u898b\u3048\u305f\u73fe\u8c61\u306f\u3001\u6cbb\u7642\u85ac\u7406\u306b\u3088\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u9650\u5c40\u6027\u5f37\u76ae\u75c7\u3068\u3044\u3046\u75be\u60a3\u304c\u672c\u6765\u6301\u3063\u3066\u3044\u308b\u300c\u81ea\u7136\u5bdb\u89e3\uff08\u6642\u9593\u7d4c\u904e\u306b\u3088\u308b\u81ea\u7136\u6d88\u9000\uff09\u300d\u3092\u89b3\u5bdf\u3057\u3066\u3044\u305f\u306b\u904e\u304e\u306a\u3044\u3053\u3068\u304c\u79d1\u5b66\u7684\u306b\u8a3c\u660e\u3055\u308c\u307e\u3057\u305f\u3002\u7d44\u7e54\u5b66\u7684\u306b\u771f\u306e\u7dda\u7dad\u5316\u6539\u5584\u304c\u78ba\u8a8d\u3055\u308c\u305f\u306e\u30826\u4f8b\u4e2d\u308f\u305a\u304b1\u4f8b\u306e\u307f\u3067\u3057\u305f\u3002 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class=\"wp-block-paragraph\">\u9650\u5c40\u6027\u5f37\u76ae\u75c7\u306e\u5c40\u6240\u7ba1\u7406\u306f\u3001\u5358\u306a\u308b\u300c\u6cbb\u7642\u524d\u5f8c\u306e\u898b\u305f\u76ee\u306e\u5909\u5316\u300d\u3060\u3051\u306b\u60d1\u308f\u3055\u308c\u308b\u3053\u3068\u306a\u304f\u3001\u5bfe\u7167\u7fa4\u3092\u8a2d\u5b9a\u3057\u305f\u79d1\u5b66\u7684\u691c\u8a3c\uff08EBM\uff09\u306b\u57fa\u3065\u304d\u3001\u771f\u306b\u52b9\u679c\u306e\u3042\u308b\u5149\u7dda\uff08UVA1\u3001NB-UVB\u3001\u30a8\u30ad\u30b7\u30de\uff09\u3092\u9069\u5207\u306b\u9078\u629e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u76ae\u819a\u306b\u751f\u3058\u305f\u308f\u305a\u304b\u306a\u5909\u5316\u304c\u3001\u7dda\u7dad\u5316\u306e\u4fb5\u653b\u3092\u544a\u3052\u308bSOS\u306a\u306e\u304b\u3001\u305d\u308c\u3068\u3082\u6642\u9593\u306e\u7d4c\u904e\u3068\u3068\u3082\u306b\u6d88\u3048\u3086\u304f\u3082\u306e\u306a\u306e\u304b\u3092\u6b63\u3057\u304f\u898b\u6975\u3081\u308b\u3053\u3068\u3001\u305d\u3057\u3066\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u88cf\u4ed8\u3051\u3089\u308c\u305f\u5b89\u5168\u306a\u5c40\u6240\u6cbb\u7642\u3092\u5c55\u958b\u3059\u308b\u3053\u3068\u3053\u305d\u304c\u3001\u5927\u5207\u306a\u76ae\u819a\u3068\u3057\u306a\u3084\u304b\u306a\u95a2\u7bc0\u3092\u751f\u6daf\u306b\u308f\u305f\u3063\u3066\u5b88\u308a\u629c\u304f\u305f\u3081\u306e\u3001\u63fa\u308b\u304e\u306a\u3044\u81e8\u5e8a\u533b\u7642\u306e\u9244\u5247\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u25a1\u30af\u30ea\u30cb\u30c3\u30af\u304b\u3089\u306e\u30e1\u30c3\u30bb\u30fc\u30b8<\/strong><\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u307e\u305f\u3001\u9650\u5c40\u6027\u5f37\u76ae\u75c7\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u81a0\u539f\u75c5\u30fb\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u304a\u53e3\u306e\u4e2d\u306e\u885b\u751f\u7ba1\u7406\uff08\u6b6f\u79d1\u7ba1\u7406\uff09\u306f\u3001\u898b\u904e\u3054\u3055\u308c\u304c\u3061\u3067\u3059\u304c\u751f\u547d\u3068\u6a5f\u80fd\u4e88\u5f8c\u306b\u95a2\u308f\u308b\u6975\u3081\u3066\u91cd\u8981\u306a\u300c\u9632\u885b\u30e9\u30a4\u30f3\u300d\u3067\u3059\u3002 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class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u5f37\u76ae\u75c7\u306e\u75be\u60a3\u6d3b\u52d5\u6027\u3092\u6291\u3048\u8fbc\u3080\u305f\u3081\u306b\u30b9\u30c6\u30ed\u30a4\u30c9\u5168\u8eab\u7642\u6cd5\u3084\u3001\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u3001\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u30e2\u30d5\u30a7\u30c1\u30eb\u3001JAK\u963b\u5bb3\u85ac\u306a\u3069\u306e\u5f37\u529b\u306a\u300c\u5168\u8eab\u514d\u75ab\u6291\u5236\u7642\u6cd5\u300d\u3092\u884c\u3063\u3066\u3044\u308b\u5c40\u9762\u3067\u306f\u3001\u4f53\u5168\u4f53\u306e\u611f\u67d3\u306b\u5bfe\u3059\u308b\u62b5\u6297\u529b\u304c\u8457\u3057\u304f\u4f4e\u4e0b\u3057\u307e\u3059\u3002 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class=\"wp-block-paragraph\">\u5f53\u9662\u306e\u6b6f\u79d1\u306f\u571f\u66dc\u65e5\u5348\u5f8c2\u6642\uff0814\u6642\uff09\u307e\u3067\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u3001\u533b\u79d1\u3068\u6b6f\u79d1\u304c\u540c\u3058\u96fb\u5b50\u30ab\u30eb\u30c6\u306e\u3082\u3068\u3067\u5b8c\u5168\u306b\u60c5\u5831\u3092\u5171\u6709\u3057\u3001\u7dca\u5bc6\u306b\u9023\u643a\u3059\u308b\u300c\u533b\u79d1\u6b6f\u79d1\u9023\u643a\u6cbb\u7642\u300d\u306e\u5f37\u307f\u3092\u6700\u5927\u9650\u306b\u6d3b\u304b\u3057\u307e\u3059\u3002 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\u304a\u53e3\u306e\u7d30\u83cc\u3092\u5b8c\u5168\u306b\u30ea\u30bb\u30c3\u30c8\u3059\u308b\u3053\u3068\u3067\u3001\u5185\u79d1\u3067\u884c\u3046\u5f37\u529b\u306a\u81a0\u539f\u75c5\u6cbb\u7642\u306e\u5b89\u5168\u6027\u3092\u98db\u8e8d\u7684\u306b\u9ad8\u3081\u3001\u9854\u9762\u3084\u624b\u306e\u5909\u5f62\u30fb\u958b\u53e3\u969c\u5bb3\u304b\u3089\u751f\u3058\u308b\u751f\u6d3b\u4e0a\u306e\u56f0\u96e3\u3092\u30c8\u30fc\u30bf\u30eb\u3067\u652f\u3048\u629c\u304d\u307e\u3059\u3002 \u9577\u5f15\u304f\u76ae\u819a\u306e\u7a81\u3063\u5f35\u308a\u3084\u8272\u629c\u3051\u3001\u95a2\u7bc0\u306e\u75db\u307f\u3001\u304a\u53e3\u306e\u958b\u304d\u306b\u304f\u3055\u3084\u4e7e\u304d\u306b\u304a\u60a9\u307f\u306e\u65b9\u306f\u3001\u304a\u6c17\u8efd\u306b\u5f53\u9662\u307e\u3067\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u25a0\u53d7\u8a3a\u3092\u3054\u5e0c\u671b\u306e\u65b9\u3078<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udc49 <strong>\u3010\u533b\u79d1\u3011\uff08\u30a2\u30ec\u30eb\u30ae\u30fc\u81a0\u539f\u75c5\u30ea\u30a6\u30de\u30c1\u5185\u79d1\u30fb\u7dcf\u5408\u5185\u79d1\u30fb\u767a\u71b1\u5916\u6765\u30fb\u76ae\u819a\u306e\u3064\u3063\u3071\u308a\u3084\u3057\u3053\u308a\u3001\u3060\u308b\u3055\u3001\u5404\u7a2e\u81a0\u539f\u75c5\u306e\u5c02\u9580\u7ba1\u7406\u76f8\u8ac7\u306a\u3069\uff09WEB\u4e88\u7d04\u306f\u3053\u3061\u3089<\/strong> \u203b\u5f53\u9662\u306e\u5185\u79d1\u30fb\u767a\u71b1\u5916\u6765\u306f\u3001\u571f\u66dc\u65e5\u5348\u5f8c\u308217\u6642\u307e\u3067\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002 <a href=\"https:\/\/melmo-app.com\/clinic\/673d5e08785f0f0030870bdb\/reservation?method=visit\" target=\"_blank\" rel=\"noopener\">https:\/\/melmo-app.com\/clinic\/673d5e08785f0f0030870bdb\/reservation?method=visit<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udc49 <strong>\u3010\u6b6f\u79d1\u3011\uff08\u6839\u7ba1\u6cbb\u7642\u30fb\u3080\u3057\u6b6f\u30fb\u6b6f\u5468\u75c5\u30fb\u958b\u53e3\u5236\u9650\u30fb\u77ef\u6b63\u6b6f\u79d1\u30fb\u30d7\u30ed\u306b\u3088\u308b\u53e3\u8154\u30b1\u30a2\u30fb\u6709\u75c5\u8005\u6b6f\u79d1\u306a\u3069\uff09WEB\u4e88\u7d04\u306f\u3053\u3061\u3089<\/strong> \u203b\u5f53\u9662\u306e\u6b6f\u79d1\u306f\u3001\u571f\u66dc\u65e5\u5348\u5f8c2\u6642\uff0814\u6642\uff09\u307e\u3067\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002 <a href=\"http:\/\/www.gomidental-kashiwa.com\/reservation\/\" target=\"_blank\" rel=\"noopener\">http:\/\/www.gomidental-kashiwa.com\/reservation\/<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udcde <strong>\u304a\u96fb\u8a71\u3067\u306e\u3054\u4e88\u7d04\u30fb\u304a\u554f\u3044\u5408\u308f\u305b\uff08\u304a\u85ac\u306e\u76f8\u8ac7\u30fb\u5065\u5eb7\u8a3a\u65ad\u30fb\u30ef\u30af\u30c1\u30f3\u306a\u3069\uff09<\/strong> \u3010\u533b\u79d1\u3011\uff1a04-7196-7531 \u3010\u6b6f\u79d1\u3011\uff1a04-7191-7081<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83c\udfe5 <strong>\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af \u30a2\u30af\u30bb\u30b9<\/strong> \u3012277-0902 \u5343\u8449\u770c\u67cf\u5e02\u5927\u4e95764-1\uff08\u5927\u4e95\u4ea4\u5dee\u70b9\u8fd1\u304f\u3001\u99d0\u8eca\u5834\u5b8c\u5099\uff09 \u30d0\u30b9\u3067\u304a\u8d8a\u3057\u306e\u65b9\uff1a\u5343\u4ee3\u7530\u5e38\u78d0\u7dda \u67cf\u99c5\u6771\u53e3 \u6771\u6b66\u30d0\u30b91\u756a\u4e57\u5834\uff08\u300c\u6cbc\u5357\u8eca\u5eab\u300d\u300c\u5c0f\u91ce\u585a\u53f0\u300d\u300c\u624b\u8cc0\u306e\u4e18\u516c\u5712\u300d\u300c\u5e03\u702c\u300d\u884c\u304d\uff09\u3088\u308a\u30d0\u30b915\u5206 \u300c\u5927\u4e95\u300d\u4e0b\u8eca \u5f92\u6b691\u5206 \u8eca\u3067\u304a\u8d8a\u3057\u306e\u65b9\uff1a\u67cf\u99c5\u3088\u308a\u7d0415\u5206<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-220.png\" alt=\"\" class=\"wp-image-8528\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-220.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-220-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-220-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-221.png\" alt=\"\" class=\"wp-image-8529\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-221.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-221-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-221-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-222.png\" alt=\"\" class=\"wp-image-8530\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-222.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-222-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-222-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-223.png\" alt=\"\" class=\"wp-image-8531\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-223.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-223-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-223-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-224.png\" alt=\"\" class=\"wp-image-8532\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-224.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-224-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-224-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-225.png\" alt=\"\" class=\"wp-image-8533\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-225.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-225-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-225-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-226.png\" alt=\"\" class=\"wp-image-8534\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-226.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-226-767x428.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-226-400x223.png 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-227.png\" alt=\"\" class=\"wp-image-8535\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-227.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-227-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-227-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-228.png\" alt=\"\" class=\"wp-image-8536\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-228.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-228-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-228-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-229.png\" alt=\"\" class=\"wp-image-8537\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-229.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-229-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-229-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-230.png\" alt=\"\" class=\"wp-image-8538\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-230.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-230-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-230-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-231.png\" alt=\"\" class=\"wp-image-8539\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-231.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-231-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-231-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-232.png\" alt=\"\" class=\"wp-image-8540\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-232.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-232-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-232-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u65e5\u672c\u76ae\u819a\u79d1\u5b66\u4f1a\u300c\u9650\u5c40\u6027\u5f37\u76ae\u75c7\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u7b56\u5b9a\u59d4\u54e1\u4f1a\u300d. \u300c\u9650\u5c40\u6027\u5f37\u76ae\u75c7\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3 2026\uff08\u7b2c 2 \u7248\uff09\u300d. \u65e5\u672c\u76ae\u819a\u79d1\u5b66\u4f1a\u96d1\u8a8c. 2026; 136(9): 1533-1584.<\/p>\n<\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\">\u25a0\u95a2\u9023\u8a18\u4e8b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>1. \u5149\u7dda\u7642\u6cd5\u306e\u9069\u5fdc\u5916\u3068\u306a\u308b\u300c\u6df1\u90e8\u75c5\u5909\u30fb\u95a2\u7bc0\u62d8\u7e2e\u300d\u306b\u5bfe\u3057\u3066\u5168\u8eab\u6295\u4e0e\uff08\u30b9\u30c6\u30ed\u30a4\u30c9\u30fbMTX\u7b49\uff09\u3092\u884c\u3046\u65b9\u3078\uff1a\u85ac\u7406\u4f5c\u7528\u3068\u5b89\u5fc3\u30fb\u5b89\u5168\u306a\u526f\u4f5c\u7528\u7ba1\u7406\u306e\u4f53\u306e\u4ed5\u7d44\u307f<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3084\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u304c\u793a\u3059\u3088\u3046\u306b\u3001\u5149\u7dda\u7642\u6cd5\u306a\u3069\u306e\u5c40\u6240\u6cbb\u7642\u3067\u306f\u5c4a\u304b\u306a\u3044\u300c\u6df1\u90e8\u75c5\u5909\u300d\u3084\u300c\u6025\u901f\u9032\u884c\u4f8b\u300d\u3092\u6291\u3048\u8fbc\u3080\u305f\u3081\u306b\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u5168\u8eab\u6295\u4e0e\u304c\u5fc5\u8981\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u308c\u3089\u306f\u6975\u3081\u3066\u9ad8\u3044\u708e\u75c7\u6291\u5236\u52b9\u679c\u3092\u6301\u3064\u4e00\u65b9\u3067\u3001\u6613\u611f\u67d3\u6027\u3084\u9aa8\u7c97\u9b06\u75c7\u3001\u8102\u8cea\u30fb\u7cd6\u4ee3\u8b1d\u7570\u5e38\u306a\u3069\u5168\u8eab\u306b\u591a\u69d8\u306a\u526f\u4f5c\u7528\u3092\u3082\u305f\u3089\u3059\u300c\u8af8\u5203\u306e\u5263\u300d\u3067\u3082\u3042\u308a\u307e\u3059\u3002\u304a\u85ac\u304c\u4f53\u5185\u3067\u679c\u305f\u3059\u751f\u7406\u7684\u306a\u5f79\u5272\u3092\u8ad6\u7406\u7684\u306b\u7406\u89e3\u3057\u3001\u5c02\u9580\u533b\u306e\u3082\u3068\u3067\u5b89\u5168\u306b\u305d\u306e\u6069\u6075\u3092\u6700\u5927\u5316\u3059\u308b\u305f\u3081\u306e\u6700\u65b0\u306e\u526f\u4f5c\u7528\u4e88\u9632\u7ba1\u7406\u306e\u4f53\u306e\u4ed5\u7d44\u307f\u3092\u5fb9\u5e95\u89e3\u8aac\u3057\u307e\u3059\u3002\u5f53\u9662\u306e\u5185\u79d1\u306f\u571f\u66dc\u65e5\u308217\u6642\u307e\u3067\u8a3a\u7642\u3092\u884c\u3063\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-7663\/\" target=\"_blank\" rel=\"noopener\">\u3010\u81a0\u539f\u75c5\u30fb\u30ea\u30a6\u30de\u30c1\u5185\u79d1\u3011\u300e\u8af8\u5203\u306e\u5263\u300f\u3092\u540d\u85ac\u306b\u5909\u3048\u308b\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u6cbb\u7642\u306e\u751f\u7406\u4f5c\u7528\u30fb\u85ac\u7406\u4f5c\u7528\u3068\u547d\u3092\u5b88\u308b\u526f\u4f5c\u7528\u7ba1\u7406 of \u306e\u4f53\u306e\u4ed5\u7d44\u307f<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>2. \u76ae\u819a\u306b\u751f\u3058\u305f\u521d\u671f\u306e\u8d64\u307f\uff08\u30e9\u30a4\u30e9\u30c3\u30af\u30ea\u30f3\u30b0\uff09\u3084\u3064\u3063\u3071\u308a\u304c\u3001\u5f37\u76ae\u75c7\u306e\u30b7\u30b0\u30ca\u30eb\u306a\u306e\u304b\u3001\u91d1\u5c5e\u30a2\u30ec\u30eb\u30ae\u30fc\u7b49\u306e\u300c\u304b\u3076\u308c\u300d\u306a\u306e\u304b\u3001\u79d1\u5b66\u7684\u306b\u9451\u5225\u3057\u305f\u3044\u65b9\u3078<\/strong><\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\"><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-5906\/\" target=\"_blank\" rel=\"noopener\">\u3010\u76ae\u819a\u79d1\u30fb\u30a2\u30ec\u30eb\u30ae\u30fc\u79d1\u3011\u304b\u3076\u308c\u3084\u5168\u8eab\u306e\u96e3\u6cbb\u6027\u76ae\u819a\u708e\u3001\u91d1\u5c5e\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u539f\u56e0\u3092\u79d1\u5b66\u7684\u306b\u7279\u5b9a\u3059\u308b\u30d1\u30c3\u30c1\u30c6\u30b9\u30c8\u306e\u4f53\u306e\u4ed5\u7d44\u307f<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>3. 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