{"id":8847,"date":"2026-09-13T13:21:49","date_gmt":"2026-09-13T04:21:49","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=8847"},"modified":"2026-09-13T14:02:11","modified_gmt":"2026-09-13T05:02:11","slug":"post-8847","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-8847\/","title":{"rendered":"\u3010NEJM2026\u3011\u9078\u629e\u7684NaV1.8\u963b\u5bb3\u85acLTG-001\u306f\u8853\u5f8c\u6025\u6027\u75db\u3092\u3069\u3053\u307e\u3067\u6291\u3048\u305f\u304b\uff1f\u7b2c2b\u76f8RCT\u3067SPID48\u6539\u5584\u3068\u30aa\u30d4\u30aa\u30a4\u30c9\u7bc0\u6e1b\u52b9\u679c"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">\u672b\u68a2\u306e\u300c\u75db\u307f\u306e\u96fb\u6c17\u4fe1\u53f7\u300d\u3092\u9078\u629e\u7684\u306b\u6291\u3048\u308b\u3001\u65b0\u3057\u3044\u975e\u30aa\u30d4\u30aa\u30a4\u30c9\u93ae\u75db\u85ac<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u624b\u8853\u5f8c\u306e\u6025\u6027\u75bc\u75db\u7ba1\u7406\u3067\u306f\u3001\u30e2\u30eb\u30d2\u30cd\u3001\u30aa\u30ad\u30b7\u30b3\u30c9\u30f3\u3001\u30d2\u30c9\u30ed\u30b3\u30c9\u30f3\u306a\u3069\u306e\u30aa\u30d4\u30aa\u30a4\u30c9\u93ae\u75db\u85ac\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3067\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u60aa\u5fc3\u30fb\u5614\u5410<\/li>\n\n\n\n<li>\u4fbf\u79d8<\/li>\n\n\n\n<li>\u7720\u6c17<\/li>\n\n\n\n<li>\u547c\u5438\u6291\u5236<\/li>\n\n\n\n<li>\u9577\u671f\u4f7f\u7528\u306b\u4f34\u3046\u4f9d\u5b58\u30fb\u4e71\u7528<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u306a\u3069\u304c\u554f\u984c\u3068\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NSAIDs\u3084\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\u3082\u8853\u5f8c\u75bc\u75db\u7ba1\u7406\u306b\u5e83\u304f\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u75db\u307f\u3067\u306f\u3001\u305d\u308c\u3060\u3051\u3067\u5341\u5206\u306a\u93ae\u75db\u304c\u5f97\u3089\u308c\u306a\u3044\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u3053\u3067\u8fd1\u5e74\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u306e\u304c\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u75db\u307f\u306e\u4fe1\u53f7\u304c\u8133\u3078\u5230\u9054\u3059\u308b\u524d\u306b\u3001\u672b\u68a2\u795e\u7d4c\u3067\u96fb\u6c17\u4fe1\u53f7\u305d\u306e\u3082\u306e\u3092\u5f31\u3081\u308b\u300d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3044\u3046\u65b0\u3057\u3044\u6cbb\u7642\u6226\u7565\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2026\u5e747\u6708\u3001\u533b\u5b66\u8a8c\u300eThe New England Journal of Medicine\uff08NEJM\uff09\u300f\u306b\u3001\u9078\u629e\u7684NaV1.8\u963b\u5bb3\u85ac <strong>LTG-001<\/strong> \u3092\u7528\u3044\u305f\u7b2c2b\u76f8\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LTG-001\u306f\u73fe\u5728\u3001onzotrigine\uff08\u30aa\u30f3\u30be\u30c8\u30ea\u30b8\u30f3\uff09\u3068\u3044\u3046\u540d\u79f0\u3067\u3082\u958b\u767a\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u308b\u6cbb\u9a13\u85ac\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-448.png\" alt=\"\" class=\"wp-image-8849\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-448.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-448-767x428.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-448-400x223.png 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">NaV1.8\u3068\u306f\uff1f\u300c\u75db\u307f\u306e\u96fb\u6c17\u4fe1\u53f7\u300d\u3092\u4f5c\u308b\u672b\u68a2\u795e\u7d4c\u306e\u30ca\u30c8\u30ea\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u75db\u307f\u306f\u5358\u306a\u308b\u300c\u611f\u899a\u300d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u76ae\u819a\u3084\u7b4b\u8089\u3001\u95a2\u7bc0\u3001\u5185\u81d3\u306a\u3069\u306b\u640d\u50b7\u304c\u751f\u3058\u308b\u3068\u3001\u672b\u68a2\u306e\u75db\u899a\u53d7\u5bb9\u5668\uff08nociceptor\uff09\u304c\u523a\u6fc0\u3055\u308c\u3001\u96fb\u6c17\u4fe1\u53f7\u304c\u767a\u751f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u4fe1\u53f7\u304c\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u672b\u68a2\u795e\u7d4c \u2192 \u810a\u9ac4 \u2192 \u8133<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3078\u4f1d\u308f\u308b\u3053\u3068\u3067\u3001\u79c1\u305f\u3061\u306f\u300c\u75db\u3044\u300d\u3068\u8a8d\u8b58\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u96fb\u6c17\u4fe1\u53f7\u306e\u767a\u751f\u3068\u4f1d\u5c0e\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u306e\u304c\u3001\u96fb\u4f4d\u4f9d\u5b58\u6027\u30ca\u30c8\u30ea\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u4e2d\u3067\u3082 <strong>NaV1.8<\/strong> \u306f\u3001\u4e3b\u306b\u672b\u68a2\u306e\u611f\u899a\u795e\u7d4c\u3001\u7279\u306b\u75db\u899a\u3092\u4f1d\u3048\u308b\u4fb5\u5bb3\u53d7\u5bb9\u30cb\u30e5\u30fc\u30ed\u30f3\u3084\u5f8c\u6839\u795e\u7d4c\u7bc0\uff08DRG\uff09\u306b\u767a\u73fe\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LTG-001\u306f\u3053\u306eNaV1.8\u3092\u9078\u629e\u7684\u306b\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u3001\u672b\u68a2\u795e\u7d4c\u304b\u3089\u810a\u9ac4\u3078\u5411\u304b\u3046\u75db\u307f\u306e\u96fb\u6c17\u4fe1\u53f7\u3092\u5f31\u3081\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30aa\u30d4\u30aa\u30a4\u30c9\u53d7\u5bb9\u4f53\u3092\u4ecb\u3057\u3066\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u4f5c\u7528\u3059\u308b\u5f93\u6765\u306e\u30aa\u30d4\u30aa\u30a4\u30c9\u3068\u306f\u3001\u4f5c\u7528\u70b9\u304c\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-457.png\" alt=\"\" class=\"wp-image-8861\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-457.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-457-400x225.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-457-768x432.png 768w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">1\uff0e343\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7b2c2b\u76f8\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306eLTG-001-010\u8a66\u9a13\u3067\u306f\u3001\u7c73\u56fd4\u65bd\u8a2d\u306b\u304a\u3044\u3066\u8179\u58c1\u5f62\u6210\u8853\uff08abdominoplasty\uff09\u3092\u53d7\u3051\u305f18\u301c65\u6b73\u306e\u60a3\u8005343\u4eba\u304c\u767b\u9332\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8853\u5f8c\u306b\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u75bc\u75db\u3092\u8a8d\u3081\u305f\u60a3\u8005\u3092\u30011\uff1a1\uff1a1\uff1a1\u30674\u7fa4\u306b\u7121\u4f5c\u70ba\u5316\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">LTG-001\u4f4e\u7528\u91cf\u7fa4\uff1a85\u4eba<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u521d\u56de300 mg<\/li>\n\n\n\n<li>\u305d\u306e\u5f8c150 mg\u309212\u6642\u9593\u3054\u3068<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">LTG-001\u9ad8\u7528\u91cf\u7fa4\uff1a86\u4eba<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u521d\u56de450 mg<\/li>\n\n\n\n<li>\u305d\u306e\u5f8c300 mg\u309212\u6642\u9593\u3054\u3068<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">\u30d2\u30c9\u30ed\u30b3\u30c9\u30f3\uff0f\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\u7fa4\uff1a86\u4eba<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30d2\u30c9\u30ed\u30b3\u30c9\u30f35 mg<\/li>\n\n\n\n<li>\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3325 mg<\/li>\n\n\n\n<li>6\u6642\u9593\u3054\u3068<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">\u30d7\u30e9\u30bb\u30dc\u7fa4\uff1a86\u4eba<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">48\u6642\u9593\u306b\u308f\u305f\u308a\u6295\u85ac\u3055\u308c\u3001\u30c0\u30d6\u30eb\u30c0\u30df\u30fc\u6cd5\u306b\u3088\u3063\u3066\u4e8c\u91cd\u76f2\u691c\u304c\u7dad\u6301\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-451.png\" alt=\"\" class=\"wp-image-8853\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-451.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-451-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-451-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">2\uff0e\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u300cSPID48\u300d\u3068\u306f\uff1f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>SPID48\uff0848\u6642\u9593\u306b\u308f\u305f\u308bPain Intensity Difference\u306e\u6642\u9593\u52a0\u91cd\u548c\uff09<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7c21\u5358\u306b\u3044\u3046\u3068\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u85ac\u3092\u98f2\u3093\u3060\u3042\u3068\u300148\u6642\u9593\u306b\u308f\u305f\u308a\u3001\u3069\u306e\u7a0b\u5ea6\u30fb\u3069\u308c\u304f\u3089\u3044\u9577\u304f\u75db\u307f\u304c\u6539\u5584\u3057\u305f\u306e\u304b\u300d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3092\u4e00\u3064\u306e\u6570\u5024\u306b\u307e\u3068\u3081\u305f\u6307\u6a19\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u8a66\u9a13\u3067\u306f0\u301c10\u70b9\u306eNumeric Pain Rating Scale\uff08NPRS\uff09\u304c\u4f7f\u7528\u3055\u308c\u3001SPID48\u306f\u6570\u5024\u304c\u5927\u304d\u3044\u307b\u3069\u300148\u6642\u9593\u3092\u901a\u3057\u305f\u93ae\u75db\u52b9\u679c\u304c\u5927\u304d\u304b\u3063\u305f\u3053\u3068\u3092\u793a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">3\uff0e\u9ad8\u7528\u91cfLTG-001\u3067\u306fSPID48\u304c185.30<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">SPID48\u306e\u6700\u5c0f\u4e8c\u4e57\u5e73\u5747\u5024\u306f\u6b21\u306e\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>LTG-001\u9ad8\u7528\u91cf\u7fa4\uff1a185.30<\/strong><\/li>\n\n\n\n<li><strong>LTG-001\u4f4e\u7528\u91cf\u7fa4\uff1a161.05<\/strong><\/li>\n\n\n\n<li><strong>\u30d2\u30c9\u30ed\u30b3\u30c9\u30f3\uff0f\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\u7fa4\uff1a164.08<\/strong><\/li>\n\n\n\n<li><strong>\u30d7\u30e9\u30bb\u30dc\u7fa4\uff1a123.22<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d7\u30e9\u30bb\u30dc\u3068\u306e\u5dee\u306f\u3001<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">LTG-001\u4f4e\u7528\u91cf<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\uff0b37.82<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">P\uff1d0.003<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">LTG-001\u9ad8\u7528\u91cf<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\uff0b62.08<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">P\uff1c0.001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3064\u307e\u308a\u3001\u4f4e\u7528\u91cf\u30fb\u9ad8\u7528\u91cf\u306e\u3044\u305a\u308c\u306b\u304a\u3044\u3066\u3082\u3001LTG-001\u306f\u30d7\u30e9\u30bb\u30dc\u3088\u308a48\u6642\u9593\u3092\u901a\u3058\u305f\u75bc\u75db\u8efd\u6e1b\u52b9\u679c\u304c\u6709\u610f\u306b\u5927\u304d\u3044\u7d50\u679c\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-452.png\" alt=\"\" class=\"wp-image-8854\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-452.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-452-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-452-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">4\uff0e\u9ad8\u7528\u91cf\u3067\u306f\u30ec\u30b9\u30ad\u30e5\u30fc\u30aa\u30d4\u30aa\u30a4\u30c9\u4f7f\u7528\u91cf\u3082\u6e1b\u5c11<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7814\u7a76\u3067\u7279\u306b\u8208\u5473\u6df1\u3044\u306e\u304c\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u75db\u307f\u304c\u6e1b\u3063\u305f\u304b\u300d\u3060\u3051\u3067\u306f\u306a\u304f\u3001\u300c\u8ffd\u52a0\u306e\u30aa\u30d4\u30aa\u30a4\u30c9\u304c\u3069\u308c\u3060\u3051\u5fc5\u8981\u3060\u3063\u305f\u304b\u300d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u3067\u8a55\u4fa1\u3057\u3066\u3044\u308b\u70b9\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u75bc\u75db\u304c\u5341\u5206\u306b\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u304d\u306a\u3044\u5834\u5408\u306b\u306f\u3001\u30ec\u30b9\u30ad\u30e5\u30fc\u85ac\u3068\u3057\u3066\u30aa\u30ad\u30b7\u30b3\u30c9\u30f3\u306e\u4f7f\u7528\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">48\u6642\u9593\u306b\u4f7f\u7528\u3055\u308c\u305f\u30ec\u30b9\u30ad\u30e5\u30fc\u30aa\u30d4\u30aa\u30a4\u30c9\u91cf\u3092\u30e2\u30eb\u30d2\u30cd\u63db\u7b97\u91cf\uff08MME\uff09\u3067\u6bd4\u8f03\u3059\u308b\u3068\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d7\u30e9\u30bb\u30dc\u7fa4\uff1a18.35 MME<\/strong><\/li>\n\n\n\n<li><strong>LTG-001\u9ad8\u7528\u91cf\u7fa4\uff1a11.00 MME<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u7528\u91cfLTG-001\u3067\u306f\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u30ec\u30b9\u30ad\u30e5\u30fc\u30aa\u30d4\u30aa\u30a4\u30c9\u4f7f\u7528\u91cf\u304c\u6709\u610f\u306b\u5c11\u306a\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>P\uff1d0.01<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u4f4e\u7528\u91cf\u7fa4\u3067\u306f\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u7dcf\u4f7f\u7528\u91cf\u306e\u6e1b\u5c11\u306b\u3064\u3044\u3066\u7d71\u8a08\u5b66\u7684\u6709\u610f\u5dee\u306f\u793a\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u30aa\u30d4\u30aa\u30a4\u30c9\u4f7f\u7528\u91cf\u305d\u306e\u3082\u306e\u3092\u6709\u610f\u306b\u6e1b\u3089\u3057\u305f\u300d\u3068\u3044\u3046\u7d50\u679c\u306f\u3001\u9ad8\u7528\u91cf\u7fa4\u3067\u78ba\u8a8d\u3055\u308c\u305f<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u7406\u89e3\u3059\u308b\u306e\u304c\u6b63\u78ba\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">5\uff0e\u7d04\u534a\u6570\u304c48\u6642\u9593\u300c\u30ec\u30b9\u30ad\u30e5\u30fc\u30aa\u30d4\u30aa\u30a4\u30c9\u4e0d\u8981\u300d<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u6ce8\u76ee\u3055\u308c\u305f\u306e\u304c\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>48\u6642\u9593\u306b\u308f\u305f\u3063\u3066\u30ec\u30b9\u30ad\u30e5\u30fc\u30aa\u30d4\u30aa\u30a4\u30c9\u3092\u4e00\u5ea6\u3082\u5fc5\u8981\u3068\u3057\u306a\u304b\u3063\u305f\u60a3\u8005\u306e\u5272\u5408<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">LTG-001\u9ad8\u7528\u91cf\u7fa4<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>52%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">LTG-001\u4f4e\u7528\u91cf\u7fa4<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>49%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u30d7\u30e9\u30bb\u30dc\u7fa4<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>22%<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u7528\u91cf\u7fa4\u3067\u306f\u3001\u7d042\u4eba\u306b1\u4eba\u304c48\u6642\u9593\u306b\u308f\u305f\u308a\u8ffd\u52a0\u306e\u30aa\u30d4\u30aa\u30a4\u30c9\u3092\u5fc5\u8981\u3068\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306fNaV1.8\u963b\u5bb3\u85ac\u304c\u5358\u306b\u75db\u307f\u306e\u30b9\u30b3\u30a2\u3092\u6539\u5584\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u8853\u5f8c\u306e\u30aa\u30d4\u30aa\u30a4\u30c9\u66dd\u9732\u305d\u306e\u3082\u306e\u3092\u6e1b\u3089\u305b\u308b\u53ef\u80fd\u6027<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3092\u793a\u5506\u3059\u308b\u91cd\u8981\u306a\u7d50\u679c\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u306f48\u6642\u9593\u3068\u3044\u3046\u77ed\u671f\u9593\u306e\u8853\u5f8c\u75bc\u75db\u30e2\u30c7\u30eb\u3067\u5f97\u3089\u308c\u305f\u7d50\u679c\u3067\u3042\u308a\u3001\u9577\u671f\u7684\u306a\u30aa\u30d4\u30aa\u30a4\u30c9\u4f7f\u7528\u3084\u4f9d\u5b58\u30ea\u30b9\u30af\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u307e\u3067\u4eca\u56de\u306e\u8a66\u9a13\u3067\u8a3c\u660e\u3055\u308c\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-458.png\" alt=\"\" class=\"wp-image-8862\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-458.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-458-768x432.png 768w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-458-400x225.png 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">6\uff0e\u610f\u5473\u306e\u3042\u308b\u75bc\u75db\u8efd\u6e1b\u306f\u7d0452\u5206\u3067\u51fa\u73fe<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u93ae\u75db\u85ac\u3067\u306f\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u3069\u308c\u3060\u3051\u52b9\u304f\u304b\u300d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3060\u3051\u3067\u306a\u304f\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u3069\u308c\u304f\u3089\u3044\u65e9\u304f\u52b9\u304f\u304b\u300d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3082\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NPRS\u304c2\u70b9\u4ee5\u4e0a\u4f4e\u4e0b\u3059\u308b\u307e\u3067\u306e\u6642\u9593\u306f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>LTG-001\u9ad8\u7528\u91cf\uff1a\u7d0452\u5206<\/strong><\/li>\n\n\n\n<li><strong>LTG-001\u4f4e\u7528\u91cf\uff1a\u7d0460\u5206<\/strong><\/li>\n\n\n\n<li><strong>\u30d2\u30c9\u30ed\u30b3\u30c9\u30f3\uff0f\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\uff1a\u7d0483\u5206<\/strong><\/li>\n\n\n\n<li><strong>\u30d7\u30e9\u30bb\u30dc\uff1a\u7d0488\u5206<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LTG-001\u3067\u306f\u3001\u7d041\u6642\u9593\u4ee5\u5185\u306b\u81e8\u5e8a\u7684\u306b\u610f\u5473\u306e\u3042\u308b\u75bc\u75db\u8efd\u6e1b\u304c\u89b3\u5bdf\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u3053\u3067\u91cd\u8981\u306a\u6ce8\u610f\u70b9\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u7528\u91cfLTG-001\u7fa4\u306eSPID48\u306f\u30d2\u30c9\u30ed\u30b3\u30c9\u30f3\uff0f\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\u7fa4\u3088\u308a\u6570\u5024\u4e0a\u5927\u304d\u304f\u3001\u75bc\u75db\u8efd\u6e1b\u307e\u3067\u306e\u6642\u9593\u3082\u77ed\u304f\u307f\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u4eca\u56de\u306e\u8a66\u9a13\u304b\u3089\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300cLTG-001\u306f\u30d2\u30c9\u30ed\u30b3\u30c9\u30f3\uff0f\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\u3088\u308a\u512a\u308c\u3066\u3044\u308b\u300d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u76f4\u63a5\u7d50\u8ad6\u3065\u3051\u308b\u3053\u3068\u306f\u9069\u5207\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u8a66\u9a13\u306e\u4e3b\u8981\u306a\u6709\u52b9\u6027\u6bd4\u8f03\u306fLTG-001\u3068\u30d7\u30e9\u30bb\u30dc\u3068\u306e\u6bd4\u8f03\u3067\u3042\u308a\u3001\u30a2\u30af\u30c6\u30a3\u30d6\u5bfe\u7167\u85ac\u306b\u5bfe\u3059\u308b\u512a\u8d8a\u6027\u3092\u78ba\u7acb\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u8a66\u9a13\u3067\u306f\u306a\u3044\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u533a\u5225\u306f\u3001\u65b0\u85ac\u306e\u81e8\u5e8a\u8a66\u9a13\u3092\u8aad\u3080\u3046\u3048\u3067\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">7\uff0e\u60aa\u5fc3\u30fb\u5614\u5410\u306fLTG-001\u7fa4\u3067\u5c11\u306a\u304b\u3063\u305f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u6cbb\u7642\u671f\u9593\u4e2d\u306b\u60aa\u5fc3\u307e\u305f\u306f\u5614\u5410\u3092\u8a8d\u3081\u305f\u5272\u5408\u306f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>LTG-001\u4f4e\u7528\u91cf\uff1a14%<\/strong><\/li>\n\n\n\n<li><strong>LTG-001\u9ad8\u7528\u91cf\uff1a16%<\/strong><\/li>\n\n\n\n<li><strong>\u30d7\u30e9\u30bb\u30dc\uff1a29%<\/strong><\/li>\n\n\n\n<li><strong>\u30d2\u30c9\u30ed\u30b3\u30c9\u30f3\uff0f\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\uff1a\u7d0431%<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u30aa\u30d4\u30aa\u30a4\u30c9\u3067\u306f\u60aa\u5fc3\u30fb\u5614\u5410\u304c\u81e8\u5e8a\u4e0a\u5927\u304d\u306a\u554f\u984c\u3068\u306a\u308b\u305f\u3081\u3001\u672b\u68a2\u795e\u7d4c\u3092\u6a19\u7684\u3068\u3059\u308b\u975e\u30aa\u30d4\u30aa\u30a4\u30c9\u93ae\u75db\u85ac\u304c\u5341\u5206\u306a\u93ae\u75db\u52b9\u679c\u3092\u6301\u3064\u3053\u3068\u304c\u3067\u304d\u308c\u3070\u3001\u8853\u5f8c\u75bc\u75db\u7ba1\u7406\u306e\u9078\u629e\u80a2\u3092\u5e83\u3052\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-454.png\" alt=\"\" class=\"wp-image-8856\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-454.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-454-400x223.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-454-767x428.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">8\uff0e\u5b89\u5168\u6027\uff1a\u767a\u71b1\u3068\u524d\u5931\u795e\u306b\u306f\u4eca\u5f8c\u3082\u6ce8\u610f\u304c\u5fc5\u8981<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5168\u6709\u5bb3\u4e8b\u8c61\u306e\u767a\u73fe\u7387\u306f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>LTG-001\u9ad8\u7528\u91cf\uff1a50%<\/strong><\/li>\n\n\n\n<li><strong>LTG-001\u4f4e\u7528\u91cf\uff1a62%<\/strong><\/li>\n\n\n\n<li><strong>\u30d2\u30c9\u30ed\u30b3\u30c9\u30f3\uff0f\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\uff1a63%<\/strong><\/li>\n\n\n\n<li><strong>\u30d7\u30e9\u30bb\u30dc\uff1a65%<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u304f\u306f\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u9ad8\u7528\u91cfLTG-001\u7fa4\u3067\u306f\u3001<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u767a\u71b1<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>7% vs \u30d7\u30e9\u30bb\u30dc2%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u524d\u5931\u795e\uff08presyncope\uff09<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7d046% vs \u30d7\u30e9\u30bb\u30dc1%<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3001\u30d7\u30e9\u30bb\u30dc\u3088\u308a\u591a\u304f\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u8005\u5224\u5b9a\u3067\u306f\u591a\u304f\u304c\u6cbb\u7642\u85ac\u3068\u306e\u95a2\u9023\u6027\u306a\u3057\u3068\u5224\u65ad\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001343\u4eba\u30fb48\u6642\u9593\u3068\u3044\u3046\u6bd4\u8f03\u7684\u5c0f\u898f\u6a21\u304b\u3064\u77ed\u671f\u9593\u306e\u8a66\u9a13\u3060\u3051\u3067\u306f\u3001\u307e\u308c\u306a\u526f\u4f5c\u7528\u3084\u9577\u671f\u5b89\u5168\u6027\u3092\u5341\u5206\u306b\u8a55\u4fa1\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u5f8c\u3001\u3088\u308a\u5927\u898f\u6a21\u306a\u7b2c3\u76f8\u8a66\u9a13\u3067\u306e\u78ba\u8a8d\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"447\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-455.png\" alt=\"\" class=\"wp-image-8857\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-455.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-455-767x428.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-455-400x223.png 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">9\uff0e\u306a\u305cNaV1.8\u963b\u5bb3\u85ac\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u306e\u304b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7814\u7a76\u304c\u91cd\u8981\u306a\u306e\u306f\u3001\u65b0\u3057\u3044\u93ae\u75db\u85ac\u304c\u4e00\u3064\u5897\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3001\u3068\u3044\u3046\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u75bc\u75db\u6cbb\u7642\u306e\u767a\u60f3\u305d\u306e\u3082\u306e\u304c\u5909\u308f\u308a\u3064\u3064\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f93\u6765\u306e\u30aa\u30d4\u30aa\u30a4\u30c9\u306f\u4e3b\u3068\u3057\u3066\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u30aa\u30d4\u30aa\u30a4\u30c9\u53d7\u5bb9\u4f53\u306b\u4f5c\u7528\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001NaV1.8\u963b\u5bb3\u85ac\u306f\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u672b\u68a2\u306e\u75db\u899a\u795e\u7d4c\u3067\u75db\u307f\u306e\u96fb\u6c17\u4fe1\u53f7\u304c\u751f\u307e\u308c\u3001\u4f1d\u308f\u3063\u3066\u3044\u304f\u6bb5\u968e<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3092\u6a19\u7684\u3068\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3064\u307e\u308a\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u8133\u3067\u75db\u307f\u306e\u611f\u3058\u65b9\u3092\u5909\u3048\u308b\u300d\u306e\u3067\u306f\u306a\u304f\u3001\u300c\u672b\u68a2\u304b\u3089\u4e0a\u304c\u3063\u3066\u304f\u308b\u75db\u307f\u306e\u4fe1\u53f7\u305d\u306e\u3082\u306e\u3092\u5f31\u3081\u308b\u300d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3044\u3046\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LTG-001\u306f\u524d\u81e8\u5e8a\u8a66\u9a13\u3067\u672b\u68a2\u795e\u7d4c\u3078\u306e\u5206\u5e03\u304c\u78ba\u8a8d\u3055\u308c\u3001\u8133\u3078\u306e\u79fb\u884c\u306f\u9650\u5b9a\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u672b\u68a2\u9078\u629e\u6027\u306f\u3001NaV1.8\u963b\u5bb3\u85ac\u304c\u975e\u30aa\u30d4\u30aa\u30a4\u30c9\u93ae\u75db\u85ac\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u308b\u7406\u7531\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u4e2d\u67a2\u79fb\u884c\u304c\u5c11\u306a\u3044\uff1d\u4f9d\u5b58\u3084\u3059\u3079\u3066\u306e\u4e2d\u67a2\u795e\u7d4c\u7cfb\u526f\u4f5c\u7528\u304c\u7d76\u5bfe\u306b\u8d77\u3053\u3089\u306a\u3044\u300d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e02\u8ca9\u5f8c\u3092\u542b\u3080\u5341\u5206\u306a\u898f\u6a21\u306e\u5b89\u5168\u6027\u30c7\u30fc\u30bf\u304c\u84c4\u7a4d\u3055\u308c\u308b\u307e\u3067\u306f\u3001\u614e\u91cd\u306a\u8a55\u4fa1\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">10\uff0e\u4eca\u56de\u306e\u7814\u7a76\u304b\u3089\u4f55\u304c\u5206\u304b\u308a\u3001\u4f55\u304c\u307e\u3060\u5206\u304b\u3089\u306a\u3044\u306e\u304b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7b2c2b\u76f8\u8a66\u9a13\u304b\u3089\u306f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>LTG-001\u306f\u8179\u58c1\u5f62\u6210\u8853\u5f8c\u306e\u4e2d\u7b49\u5ea6\u301c\u91cd\u5ea6\u6025\u6027\u75db\u306b\u304a\u3044\u3066\u3001\u30d7\u30e9\u30bb\u30dc\u3088\u308aSPID48\u3092\u6709\u610f\u306b\u6539\u5584\u3057\u305f<\/li>\n\n\n\n<li>\u9ad8\u7528\u91cf\u7fa4\u3067\u306f\u30ec\u30b9\u30ad\u30e5\u30fc\u30aa\u30d4\u30aa\u30a4\u30c9\u4f7f\u7528\u91cf\u304c\u6709\u610f\u306b\u6e1b\u5c11\u3057\u305f<\/li>\n\n\n\n<li>\u9ad8\u7528\u91cf\u7fa4\u306e\u7d0452%\u304c48\u6642\u9593\u30ec\u30b9\u30ad\u30e5\u30fc\u30aa\u30d4\u30aa\u30a4\u30c9\u3092\u5fc5\u8981\u3068\u3057\u306a\u304b\u3063\u305f<\/li>\n\n\n\n<li>\u7d041\u6642\u9593\u4ee5\u5185\u3068\u3044\u3046\u6bd4\u8f03\u7684\u901f\u3044\u75bc\u75db\u8efd\u6e1b\u304c\u89b3\u5bdf\u3055\u308c\u305f<\/li>\n\n\n\n<li>\u60aa\u5fc3\u30fb\u5614\u5410\u306fLTG-001\u7fa4\u3067\u5c11\u306a\u304b\u3063\u305f<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3067\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30d2\u30c9\u30ed\u30b3\u30c9\u30f3\uff0f\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\u306b\u5bfe\u3059\u308b\u512a\u8d8a\u6027<\/li>\n\n\n\n<li>\u4ed6\u306e\u624b\u8853\u3084\u5916\u50b7\u3067\u3082\u540c\u3058\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b\u304b<\/li>\n\n\n\n<li>\u9ad8\u9f62\u8005\u3084\u591a\u6570\u306e\u4f75\u5b58\u75be\u60a3\u3092\u6301\u3064\u60a3\u8005\u3067\u306e\u6709\u52b9\u6027\u30fb\u5b89\u5168\u6027<\/li>\n\n\n\n<li>\u6570\u65e5\u301c\u6570\u9031\u9593\u4f7f\u7528\u3057\u305f\u5834\u5408\u306e\u5b89\u5168\u6027<\/li>\n\n\n\n<li>\u307e\u308c\u306a\u6709\u5bb3\u4e8b\u8c61<\/li>\n\n\n\n<li>\u5b9f\u81e8\u5e8a\u3067\u30aa\u30d4\u30aa\u30a4\u30c9\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\u3084\u4f9d\u5b58\u3092\u3069\u306e\u7a0b\u5ea6\u6e1b\u3089\u305b\u308b\u304b<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u306b\u3064\u3044\u3066\u306f\u3001\u307e\u3060\u78ba\u7acb\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u975e\u5e38\u306b\u6709\u671b\u306a\u7b2c2b\u76f8\u8a66\u9a13\u300d\u3067\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u300c\u65b0\u3057\u3044\u6a19\u6e96\u6cbb\u7642\u304c\u78ba\u7acb\u3057\u305f\u300d\u3068\u8a55\u4fa1\u3059\u308b\u6bb5\u968e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u5f8c\u306e\u7b2c3\u76f8\u8a66\u9a13\u304c\u91cd\u8981\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u307e\u3068\u3081<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">NaV1.8\u306f\u3001\u672b\u68a2\u306e\u75db\u899a\u795e\u7d4c\u306b\u5b58\u5728\u3057\u3001\u75db\u307f\u306e\u96fb\u6c17\u4fe1\u53f7\u3092\u767a\u751f\u30fb\u4f1d\u5c0e\u3059\u308b\u3046\u3048\u3067\u91cd\u8981\u306a\u30ca\u30c8\u30ea\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7b2c2b\u76f8\u8a66\u9a13\u3067\u306f\u3001\u9078\u629e\u7684NaV1.8\u963b\u5bb3\u85acLTG-001\u304c\u8179\u58c1\u5f62\u6210\u8853\u5f8c\u306e\u6025\u6027\u75bc\u75db\u306b\u5bfe\u3057\u3066\u30d7\u30e9\u30bb\u30dc\u3088\u308a\u6709\u610f\u306b\u9ad8\u3044\u93ae\u75db\u52b9\u679c\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u9ad8\u7528\u91cf\u7fa4\u3067\u306f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>SPID48\uff1a185.30<\/strong><\/li>\n\n\n\n<li><strong>\u30d7\u30e9\u30bb\u30dc\u3068\u306e\u5dee\uff1a\uff0b62.08<\/strong><\/li>\n\n\n\n<li><strong>\u30ec\u30b9\u30ad\u30e5\u30fc\u30aa\u30d4\u30aa\u30a4\u30c9\uff1a11.00 MME<\/strong><\/li>\n\n\n\n<li><strong>\u7d0452%\u304c48\u6642\u9593\u30ec\u30b9\u30ad\u30e5\u30fc\u30aa\u30d4\u30aa\u30a4\u30c9\u4e0d\u8981<\/strong><\/li>\n\n\n\n<li><strong>\u610f\u5473\u306e\u3042\u308b\u75bc\u75db\u8efd\u6e1b\u307e\u3067\u7d0452\u5206<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3044\u3046\u7d50\u679c\u304c\u5f97\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u300c\u75db\u307f\u3092\u8133\u3067\u6291\u3048\u308b\u300d\u306e\u3067\u306f\u306a\u304f\u3001\u672b\u68a2\u795e\u7d4c\u3067\u75db\u307f\u306e\u4fe1\u53f7\u305d\u306e\u3082\u306e\u3092\u6291\u3048\u308b<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3044\u3046\u65b0\u3057\u3044\u975e\u30aa\u30d4\u30aa\u30a4\u30c9\u93ae\u75db\u6226\u7565\u306e\u53ef\u80fd\u6027\u3092\u793a\u3057\u305f\u7814\u7a76\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001LTG-001\u306f\u73fe\u6642\u70b9\u3067\u306f\u958b\u767a\u4e2d\u306e\u6cbb\u9a13\u85ac\u3067\u3042\u308a\u3001\u9577\u671f\u5b89\u5168\u6027\u3084\u5e45\u5e83\u3044\u60a3\u8005\u96c6\u56e3\u306b\u304a\u3051\u308b\u52b9\u679c\u306b\u3064\u3044\u3066\u306f\u3001\u4eca\u5f8c\u306e\u7b2c3\u76f8\u8a66\u9a13\u306b\u3088\u308b\u691c\u8a3c\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-459.png\" alt=\"\" class=\"wp-image-8863\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-459.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-459-768x432.png 768w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/09\/image-459-400x225.png 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u25a1\u30af\u30ea\u30cb\u30c3\u30af\u304b\u3089\u306e\u30e1\u30c3\u30bb\u30fc\u30b8<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u75db\u307f\u306f\u3001\u3059\u3079\u3066\u540c\u3058\u4ed5\u7d44\u307f\u3067\u751f\u3058\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f8b\u3048\u3070\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u95a2\u7bc0\u708e\u306a\u3069\u306e\u300c\u708e\u75c7\u6027\u30fb\u4fb5\u5bb3\u53d7\u5bb9\u6027\u75bc\u75db\u300d<\/li>\n\n\n\n<li>\u672b\u68a2\u795e\u7d4c\u969c\u5bb3\u306b\u3088\u308b\u300c\u795e\u7d4c\u969c\u5bb3\u6027\u75bc\u75db\u300d<\/li>\n\n\n\n<li>\u7dda\u7dad\u7b4b\u75db\u75c7\u306a\u3069\u3067\u307f\u3089\u308c\u308b\u300c\u75db\u899a\u5909\u8abf\u6027\u75bc\u75db\u300d<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3067\u306f\u3001\u9069\u5207\u306a\u8a55\u4fa1\u65b9\u6cd5\u3084\u6cbb\u7642\u85ac\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u3001\u7dcf\u5408\u5185\u79d1\u5c02\u9580\u533b\u30fb\u30ea\u30a6\u30de\u30c1\u5c02\u9580\u533b\u3001\u304a\u3088\u3073\u809d\u81d3\u5c02\u9580\u533b\u304c\u9023\u643a\u3057\u3001\u95a2\u7bc0\u75db\u3084\u5168\u8eab\u306e\u75db\u307f\u306b\u3064\u3044\u3066\u300c\u3068\u308a\u3042\u3048\u305a\u75db\u307f\u6b62\u3081\u3092\u51fa\u3059\u300d\u306e\u3067\u306f\u306a\u304f\u3001\u708e\u75c7\u3001\u795e\u7d4c\u3001\u81d3\u5668\u969c\u5bb3\u3001\u85ac\u5264\u526f\u4f5c\u7528\u306a\u3069\u3092\u7dcf\u5408\u7684\u306b\u8a55\u4fa1\u3057\u305f\u3046\u3048\u3067\u6cbb\u7642\u65b9\u91dd\u3092\u691c\u8a0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u95a2\u7bc0\u306e\u816b\u308c\u3084\u75db\u307f\u3001\u624b\u8db3\u306e\u3057\u3073\u308c\u3001\u539f\u56e0\u306e\u5206\u304b\u3089\u306a\u3044\u5168\u8eab\u75db\u306a\u3069\u304c\u7d9a\u304f\u5834\u5408\u306b\u306f\u3001\u75db\u307f\u306e\u80cc\u666f\u306b\u3042\u308b\u75c5\u614b\u3092\u6574\u7406\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u203bLTG-001\uff08onzotrigine\uff09\u306f\u73fe\u5728\u958b\u767a\u4e2d\u306e\u85ac\u5264\u3067\u3042\u308a\u3001\u5f53\u9662\u3067\u51e6\u65b9\u3067\u304d\u308b\u85ac\u5264\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u672c\u8a18\u4e8b\u306f\u6700\u65b0\u533b\u5b66\u7814\u7a76\u306e\u89e3\u8aac\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u25a0\u53d7\u8a3a\u3092\u3054\u5e0c\u671b\u306e\u65b9\u3078<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udc49 <strong><a href=\"https:\/\/melmo-app.com\/clinic\/673d5e08785f0f0030870bdb\/reservation?method=visit\" target=\"_blank\" rel=\"noopener\">\u3010\u533b\u79d1\u3011\u30a2\u30ec\u30eb\u30ae\u30fc\u81a0\u539f\u75c5\u30ea\u30a6\u30de\u30c1\u5185\u79d1\u30fb\u7dcf\u5408\u5185\u79d1\u30fb\u767a\u71b1\u5916\u6765\u30fb\u95a2\u7bc0\u75db\u30fb\u5404\u7a2e\u8840\u6db2\uff0f\u753b\u50cf\u691c\u67fb\u306a\u3069<\/a><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f53\u9662\u306e\u5185\u79d1\u306f\u571f\u66dc\u65e5\u308217\u6642\u307e\u3067\u8a3a\u7642\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udc49 <strong><a href=\"http:\/\/www.gomidental-kashiwa.com\/reservation\/\" target=\"_blank\" rel=\"noopener\">\u3010\u6b6f\u79d1\u3011\u6839\u7ba1\u6cbb\u7642\u30fb\u3080\u3057\u6b6f\u30fb\u6b6f\u5468\u75c5\u30fb\u53e3\u8154\u30b1\u30a2\u30fb\u6709\u75c5\u8005\u6b6f\u79d1\u30fbPMTC\u306a\u3069<\/a><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5f53\u9662\u306e\u6b6f\u79d1\u306f\u571f\u66dc\u65e514\u6642\u307e\u3067\u8a3a\u7642\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83d\udcde <strong>\u304a\u96fb\u8a71\u3067\u306e\u3054\u4e88\u7d04\u30fb\u304a\u554f\u3044\u5408\u308f\u305b<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3010\u533b\u79d1\u301104-7196-7531<br>\u3010\u6b6f\u79d1\u301104-7191-7081<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ud83c\udfe5 <strong>\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3012277-0902<br>\u5343\u8449\u770c\u67cf\u5e02\u5927\u4e95764-1<br>\u5927\u4e95\u4ea4\u5dee\u70b9\u8fd1\u304f\u30fb\u99d0\u8eca\u5834\u5b8c\u5099<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u25a0\u6b63\u5f0f\u306a\u5f15\u7528\u6587<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Neil Singla, Nathaniel P. Katz, Ben Vaughn, Timothy Rogier, Todd Bertoch, Harold Minkowitz, Mallory Loflin.<br>\u201cPhase 2b Trial of a NaV1.8 Inhibitor for Acute Pain.\u201d<br><em>The New England Journal of Medicine<\/em>. 2026;395(5):454-464.<br>DOI: 10.1056\/NEJMoa2602910<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u25a0\u3042\u308f\u305b\u3066\u8aad\u307f\u305f\u3044\u95a2\u9023\u8a18\u4e8b<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1\uff0e\u6025\u6027\u306e\u75db\u307f\u306b\u300c\u93ae\u75db\u85ac\u3092\u8ffd\u52a0\u3059\u308c\u3070\u3059\u308b\u307b\u3069\u52b9\u304f\u300d\u3068\u306f\u9650\u3089\u306a\u3044\u7406\u7531\u3092\u77e5\u308a\u305f\u3044\u65b9\u3078<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-6542\/\" target=\"_blank\" rel=\"noopener\">\u3010\u7dcf\u5408\u5185\u79d1\u3011\u5b50\u3069\u3082\u306e\u30b1\u30ac\u306b\u300c\u8907\u6570\u306e\u75db\u307f\u6b62\u3081\u300d\u306f\u610f\u5473\u304c\u306a\u3044\uff1fNo OUCH\u8a66\u9a13\u304c\u660e\u304b\u3059\u6b63\u3057\u3044\u93ae\u75db\u85ac\u306e\u9078\u3073\u65b9\u3068\u4f53\u306e\u4ed5\u7d44\u307f<\/a><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6025\u6027\u75bc\u75db\u3067\u306f\u3001\u5f37\u3044\u85ac\u3092\u6b21\u3005\u306b\u8ffd\u52a0\u3059\u308b\u3053\u3068\u304c\u5fc5\u305a\u3057\u3082\u512a\u308c\u305f\u93ae\u75db\u306b\u3064\u306a\u304c\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p 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