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class=\"wp-block-paragraph\">\u3055\u3089\u306b\u7d4c\u53e3\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u3059\u3079\u3066\u306e\u6297\u767d\u8840\u75c5\u85ac\u3092\u7d4c\u53e3\u6295\u4e0e\u3059\u308b\u30ec\u30b8\u30e1\u30f3\u304c\u6210\u7acb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001<strong>\u85ac\u7269\u66dd\u9732\u306e\u540c\u7b49\u6027\u306f\u3001\u6cbb\u7642\u52b9\u679c\u3084\u5b89\u5168\u6027\u306e\u540c\u7b49\u6027\u3092\u76f4\u63a5\u8a3c\u660e\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u81e8\u5e8a\u7684\u306a\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u3092\u8a55\u4fa1\u3057\u305f\u7814\u7a76\u304cASCERTAIN-V\u8a66\u9a13\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"566\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-118.png\" alt=\"\u6025\u6027\u9aa8\u9ac4\u6027\u767d\u8840\u75c5\u306b\u304a\u3051\u308bDNA\u4f4e\u30e1\u30c1\u30eb\u5316\u85ac\u3068BCL-2\u963b\u5bb3\u85ac\u306e\u4f5c\u7528\u6a5f\u5e8f\" class=\"wp-image-9343\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-118.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-118-400x283.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-118-767x543.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><strong>\u56f31\uff1a\u6025\u6027\u9aa8\u9ac4\u6027\u767d\u8840\u75c5\uff08AML\uff09\u306b\u5bfe\u3059\u308b\u5b8c\u5168\u7d4c\u53e3\u4f75\u7528\u7642\u6cd5\u306e\u85ac\u7406\u5b66\u7684\u4f5c\u7528\u6a5f\u5e8f<\/strong><br><\/strong>\u30c7\u30b7\u30bf\u30d3\u30f3\u306fDNA\u30e1\u30c1\u30eb\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc\uff08DNMT\uff09\u3092\u963b\u5bb3\u3057\u3001DNA\u30e1\u30c1\u30eb\u5316\u5236\u5fa1\u306b\u4ecb\u5165\u3059\u308b\u3002\u30bb\u30c0\u30ba\u30ea\u30b8\u30f3\u306f\u30b7\u30c1\u30b8\u30f3\u30c7\u30a2\u30df\u30ca\u30fc\u30bc\uff08CDA\uff09\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u7d4c\u53e3\u30c7\u30b7\u30bf\u30d3\u30f3\u306e\u5206\u89e3\u3092\u6291\u5236\u3057\u3001\u5168\u8eab\u66dd\u9732\u91cf\u3092\u9ad8\u3081\u308b\u3002\u4e00\u65b9\u3001\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u306f\u6297\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u30bf\u30f3\u30d1\u30af\u8ceaBCL-2\u3092\u963b\u5bb3\u3057\u3001\u767d\u8840\u75c5\u7d30\u80de\u306e\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u3092\u4fc3\u9032\u3059\u308b\u3002\u4e21\u6cbb\u7642\u7d4c\u8def\u3092\u6a21\u5f0f\u7684\u306b\u793a\u3057\u305f\u56f3\u3067\u3042\u308a\u3001\u81e8\u5e8a\u7684\u76f8\u4e57\u52b9\u679c\u3092\u76f4\u63a5\u8a3c\u660e\u3059\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4\uff0eASCERTAIN-V\u8a66\u9a13\u306e\u7814\u7a76\u30c7\u30b6\u30a4\u30f3<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">2026\u5e74\u306bNEJM\u306b\u767a\u8868\u3055\u308c\u305fASCERTAIN-V\u8a66\u9a13\u306f\u3001\u5f37\u529b\u306a\u5bdb\u89e3\u5c0e\u5165\u5316\u5b66\u7642\u6cd5\u304c\u9069\u3055\u306a\u3044\u65b0\u898f\u8a3a\u65adAML\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3001\u7b2c1\uff5e2\u76f8\u306e\u591a\u65bd\u8a2d\u5171\u540c\u81e8\u5e8a\u8a66\u9a13\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u306e\u7279\u5fb4\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u9805\u76ee<\/th><th>\u7814\u7a76\u5185\u5bb9<\/th><\/tr><tr><td>\u8a66\u9a13\u540d<\/td><td>ASCERTAIN-V\uff08ASTX727-07\uff09<\/td><\/tr><tr><td>\u7814\u7a76\u30c7\u30b6\u30a4\u30f3<\/td><td>\u7b2c1\uff5e2\u76f8\u3001\u975e\u76f2\u691c\u3001\u975e\u30e9\u30f3\u30c0\u30e0\u5316\u3001\u5358\u7fa4\u4ecb\u5165\u8a66\u9a13<\/td><\/tr><tr><td>\u5b9f\u65bd\u65bd\u8a2d<\/td><td>\u7c73\u56fd\u30fb\u30ab\u30ca\u30c0\u30fb\u30b9\u30da\u30a4\u30f3\u306e34\u65bd\u8a2d<\/td><\/tr><tr><td>\u5bfe\u8c61<\/td><td>\u65b0\u898f\u8a3a\u65adAML\u300175\u6b73\u4ee5\u4e0a\u307e\u305f\u306f\u5f37\u529b\u306a\u5316\u5b66\u7642\u6cd5\u304c\u4e0d\u9069<\/td><\/tr><tr><td>\u767b\u9332\u60a3\u8005<\/td><td>\u5408\u8a08189\u4f8b<\/td><\/tr><tr><td>Phase 1<\/td><td>30\u4f8b<\/td><\/tr><tr><td>Phase 2a<\/td><td>58\u4f8b<\/td><\/tr><tr><td>Phase 2b<\/td><td>101\u4f8b<\/td><\/tr><tr><td>\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee<\/td><td>\u85ac\u7269\u52d5\u614b\u304a\u3088\u3073\u5b8c\u5168\u5bdb\u89e3\u7387<\/td><\/tr><tr><td>\u81e8\u5e8a\u8a66\u9a13\u767b\u9332<\/td><td>NCT04657081<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u306f\u6bb5\u968e\u7684\u306b\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 1\u3067\u306f\u4e3b\u3068\u3057\u3066\u85ac\u7269\u9593\u76f8\u4e92\u4f5c\u7528\u3084\u85ac\u7269\u52d5\u614b\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 2a\u3067\u306f\u85ac\u7269\u52d5\u614b\u3068\u81e8\u5e8a\u7684\u6709\u52b9\u6027\u3092\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u3057\u3066\u3001\u4e2d\u5fc3\u7684\u306a\u6709\u52b9\u6027\u8a55\u4fa1\u3092\u62c5\u3063\u305fPhase 2b\u3067\u306f101\u4f8b\u3092\u5bfe\u8c61\u306b\u5b8c\u5168\u5bdb\u89e3\u7387\u3092\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u3068\u3057\u3066\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 2b\u60a3\u8005\u306e\u5e74\u9f62\u4e2d\u592e\u5024\u306f78\u6b73\u3067\u3001TP53\u5909\u7570\u306f17%\u3001ELN 2017\u306b\u3088\u308b\u4e0d\u826f\u67d3\u8272\u4f53\u30ea\u30b9\u30af\u306f24%\u306b\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u8a66\u9a13\u306b\u306f\u30a2\u30b6\u30b7\u30c1\u30b8\u30f3\uff0b\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u306a\u3069\u306e\u540c\u6642\u5bfe\u7167\u7fa4\u304c\u5b58\u5728\u3057\u306a\u3044\u305f\u3081\u3001\u5f93\u6765\u6cbb\u7642\u3068\u306e\u76f4\u63a5\u6bd4\u8f03\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"566\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-119.png\" alt=\"ASCERTAIN-V\u8a66\u9a13\u306e3\u6bb5\u968e\u306e\u8a66\u9a13\u30c7\u30b6\u30a4\u30f3\u3068\u60a3\u8005\u6570\" class=\"wp-image-9344\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-119.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-119-400x283.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-119-767x543.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f32\uff1aASCERTAIN-V\u8a66\u9a13\u306e\u69cb\u6210<\/strong><br>Phase 1\u30012a\u30012b\u306e\u5bfe\u8c61\u4eba\u6570\u3068\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u3092\u6574\u7406\u3057\u305f\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u56f3\u3002\u767b\u9332189\u4f8b\u3092Phase 1\uff0830\u4f8b\uff09\u30012a\uff0858\u4f8b\uff09\u30012b\uff08101\u4f8b\uff09\u306b\u5206\u985e\u3057\u305f\u975e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u306e\u69cb\u6210\u3002\u7fa4\u9593\u3067\u5272\u4ed8\u6bd4\u8f03\u3092\u5b9f\u65bd\u3057\u305f\u7814\u7a76\u3067\u306f\u306a\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5\uff0e\u5b9f\u969b\u306e\u6cbb\u7642\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u3068\u9aa8\u9ac4\u6291\u5236\u3078\u306e\u5bfe\u7b56<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u57fa\u672c\u30ec\u30b8\u30e1\u30f3\u306f28\u65e5\u30921\u30b5\u30a4\u30af\u30eb\u3068\u3057\u3066\u8a2d\u8a08\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30c7\u30b7\u30bf\u30d3\u30f3\u30fb\u30bb\u30c0\u30ba\u30ea\u30b8\u30f3<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30c7\u30b7\u30bf\u30d3\u30f335 mg\uff0b\u30bb\u30c0\u30ba\u30ea\u30b8\u30f3100 mg<\/li>\n\n\n\n<li>\u5404\u30b5\u30a4\u30af\u30eb\u306e\u7b2c1\uff5e5\u65e5\u306b\u7d4c\u53e3\u6295\u4e0e<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u521d\u56de\u306f\u816b\u760d\u5d29\u58ca\u75c7\u5019\u7fa4\u3092\u9632\u3050\u305f\u3081\u6bb5\u968e\u7684\u306b\u5897\u91cf<\/li>\n\n\n\n<li>\u7b2c1\u65e5\uff1a100 mg<\/li>\n\n\n\n<li>\u7b2c2\u65e5\uff1a200 mg<\/li>\n\n\n\n<li>\u7b2c3\u65e5\u4ee5\u964d\uff1a\u539f\u5247400 mg\/\u65e5<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u6297\u771f\u83cc\u85ac\u4f75\u7528\u6642\u306b\u306f\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u3092\u8003\u616e\u3057\u305f\u7528\u91cf\u8abf\u6574\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u7814\u7a76\u3067\u91cd\u8981\u306a\u306e\u306f\u3001\u6295\u4e0e\u3092\u7d4c\u53e3\u5316\u3057\u305f\u3060\u3051\u3067\u306f\u306a\u304f\u3001<strong>\u5bdb\u89e3\u5f8c\u306b\u9aa8\u9ac4\u6291\u5236\u3092\u8efd\u6e1b\u3059\u308b\u305f\u3081\u6295\u4e0e\u65e5\u6570\u3092\u77ed\u7e2e\u3059\u308b\u6226\u7565<\/strong>\u3092\u53d6\u308a\u5165\u308c\u305f\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u521d\u671f\u306e\u8a66\u9a13\u6bb5\u968e\u3067\u306f\u3001\u9577\u671f\u306e\u597d\u4e2d\u7403\u6e1b\u5c11\u306a\u3069\u304c\u554f\u984c\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u3053\u3067Phase 2b\u3067\u306f\u3001\u6cbb\u7642\u958b\u59cb\u304b\u3089\u7d0421\u65e5\u76ee\u306b\u9aa8\u9ac4\u691c\u67fb\u3092\u884c\u3044\u3001\u9aa8\u9ac4\u82bd\u7403\u304c5%\u672a\u6e80\u306b\u6e1b\u5c11\u3057\u305f\u5834\u5408\u3001\u8840\u7403\u56de\u5fa9\u307e\u3067\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u3092\u4f11\u85ac\u3059\u308b\u65b9\u6cd5\u304c\u63a8\u5968\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b21\u30b5\u30a4\u30af\u30eb\u4ee5\u964d\u306f\u3001\u56de\u5fa9\u306b\u8981\u3059\u308b\u65e5\u6570\u306b\u5fdc\u3058\u3066\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u309221\u65e5\u9593\u300114\u65e5\u9593\u3001\u5834\u5408\u306b\u3088\u3063\u3066\u306f7\u65e5\u9593\u3078\u3068\u77ed\u7e2e\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30c7\u30b7\u30bf\u30d3\u30f3\u30fb\u30bb\u30c0\u30ba\u30ea\u30b8\u30f3\u306b\u3064\u3044\u3066\u3082\u3001\u5f53\u521d\u306e5\u65e5\u9593\u304b\u30893\uff5e4\u65e5\u9593\u3078\u306e\u77ed\u7e2e\u304c\u8a31\u5bb9\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5fc5\u8981\u306b\u5fdc\u3058\u3066G-CSF\u3082\u4f7f\u7528\u3057\u3001\u597d\u4e2d\u7403\u56de\u5fa9\u3092\u652f\u63f4\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u65b9\u6cd5\u306f\u3001\u6cbb\u7642\u52b9\u679c\u3092\u78ba\u4fdd\u3057\u306a\u304c\u3089\u9aa8\u9ac4\u6291\u5236\u3092\u7ba1\u7406\u3059\u308b\u3046\u3048\u3067\u3001\u91cd\u8981\u306a\u81e8\u5e8a\u7684\u5de5\u592b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u306a\u304a\u3001\u3053\u3053\u3067\u793a\u3057\u305f\u6295\u4e0e\u91cf\u30fb\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u306f\u539f\u8457\u8a66\u9a13\u306e\u65b9\u6cd5\u3067\u3042\u308a\u3001\u65e5\u672c\u56fd\u5185\u3067\u306e\u627f\u8a8d\u7528\u6cd5\u3084\u500b\u3005\u306e\u60a3\u8005\u3055\u3093\u3078\u306e\u51e6\u65b9\u3092\u793a\u3059\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6\uff0e\u4e3b\u8981\u7d50\u679c\u2460\uff5c\u5b8c\u5168\u5bdb\u89e3\u7387\u306f47%\u3001CR\uff0bCRi\u7387\u306f63%<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 2b\u306e\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u3067\u3042\u308b\u5b8c\u5168\u5bdb\u89e3\u7387\uff08Complete Response\uff1aCR\uff09\u306f47%\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">95%\u4fe1\u983c\u533a\u9593\u306f36\uff5e57%\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u5b8c\u5168\u5bdb\u89e3\u307e\u305f\u306f\u8840\u7403\u56de\u5fa9\u304c\u4e0d\u5341\u5206\u306a\u5b8c\u5168\u5bdb\u89e3\uff08CR\uff0bCRi\uff09\u306f63%\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u8a55\u4fa1\u9805\u76ee<\/th><th>Phase 2b\uff08101\u4f8b\uff09<\/th><\/tr><tr><td>\u5b8c\u5168\u5bdb\u89e3\uff08CR\uff09<\/td><td>47%\uff0895% CI 36\u201357\uff09<\/td><\/tr><tr><td>\u8840\u7403\u56de\u5fa9\u4e0d\u5b8c\u5168\u306a\u5b8c\u5168\u5bdb\u89e3\uff08CRi\uff09<\/td><td>17%\uff0895% CI 10\u201326\uff09<\/td><\/tr><tr><td>CR\uff0bCRi<\/td><td>63%\uff0895% CI 53\u201373\uff09<\/td><\/tr><tr><td>\u90e8\u5206\u7684\u8840\u7403\u56de\u5fa9\u3092\u4f34\u3046\u5b8c\u5168\u5bdb\u89e3\uff08CRh\uff09<\/td><td>5%\uff0895% CI 2\u201311\uff09<\/td><\/tr><tr><td>\u5b8c\u5168\u5bdb\u89e3\u307e\u3067\u306e\u671f\u9593\u4e2d\u592e\u5024<\/td><td>2.4\u304b\u6708<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3053\u3067\u3044\u3046\u5b8c\u5168\u5bdb\u89e3\u306f\u3001\u9aa8\u9ac4\u4e2d\u306e\u767d\u8840\u75c5\u7d30\u80de\u304c\u5341\u5206\u306b\u6e1b\u5c11\u3057\u3001\u4e00\u5b9a\u306e\u8840\u7403\u56de\u5fa9\u3092\u6e80\u305f\u3059\u72b6\u614b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001CRi\u3067\u306f\u767d\u8840\u75c5\u7d30\u80de\u304c\u5341\u5206\u306b\u6e1b\u5c11\u3057\u3066\u3044\u3066\u3082\u3001\u597d\u4e2d\u7403\u6570\u307e\u305f\u306f\u8840\u5c0f\u677f\u6570\u306a\u3069\u306e\u56de\u5fa9\u304c\u4e0d\u5341\u5206\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3064\u307e\u308a\u3001CR\uff0bCRi\u7387\u304c63%\u3067\u3042\u308b\u3053\u3068\u306f\u300163%\u306e\u60a3\u8005\u3055\u3093\u3067\u767d\u8840\u75c5\u304c\u6cbb\u7652\u3057\u305f\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 2b\u3067\u306f\u3001\u5b8c\u5168\u5bdb\u89e3\u7387\u306e95%\u4fe1\u983c\u533a\u9593\u306e\u4e0b\u9650\u304c17.9%\u3092\u4e0a\u56de\u308b\u3053\u3068\u304c\u4e8b\u524d\u898f\u5b9a\u3055\u308c\u305f\u6709\u52b9\u6027\u5224\u5b9a\u57fa\u6e96\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5b9f\u969b\u306e\u4e0b\u9650\u306f36%\u3067\u3042\u308a\u3001\u3053\u306e\u57fa\u6e96\u3092\u6e80\u305f\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u306e17.9%\u306f\u904e\u53bb\u306e\u4f4e\u30e1\u30c1\u30eb\u5316\u85ac\u5358\u5264\u6cbb\u7642\u306b\u7531\u6765\u3059\u308b\u95be\u5024\u3067\u3042\u308a\u3001\u540c\u6642\u5bfe\u7167\u7fa4\u3068\u306e\u6bd4\u8f03\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"566\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-120.png\" alt=\"ASCERTAIN-V Phase 2b\u306b\u304a\u3051\u308b\u5b8c\u5168\u5bdb\u89e3\u738747%\u3068CR\uff0bCRi\u738763%\" class=\"wp-image-9346\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-120.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-120-400x283.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-120-767x543.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f33\uff1a\u5b8c\u5168\u5bdb\u89e3\u7387\u3068CR\uff0bCRi\u7387<\/strong>\u3000CR 47%\uff0895% CI 36\u201357\uff09\u3001CR\uff0bCRi 63%\uff0895% CI 53\u201373\uff09\u309295%\u4fe1\u983c\u533a\u9593\u4ed8\u304d\u3067\u8868\u793a\u3002Phase 2b\u5168\u6cbb\u7642\u96c6\u56e3101\u4f8b\u306b\u304a\u3051\u308b\u594f\u52b9\u5272\u5408\u3002CR\uff0bCRi\u306fCR\u3092\u5185\u5305\u3059\u308b\u8907\u5408\u6307\u6a19\u3067\u3042\u308a\u3001\u72ec\u7acb\u3057\u305f2\u7fa4\u3067\u306f\u306a\u3044\u300295% CI\u306fClopper\u2013Pearson\u6cd5\u306b\u57fa\u3065\u304f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">7\uff0e\u4e3b\u8981\u7d50\u679c\u2461\uff5c\u5168\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\u306f15.5\u304b\u6708<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5168\u751f\u5b58\u671f\u9593\uff08Overall Survival\uff1aOS\uff09\u306f\u3001\u6cbb\u7642\u958b\u59cb\u304b\u3089\u6b7b\u4ea1\u307e\u3067\u306e\u671f\u9593\u3092\u8868\u3059\u6307\u6a19\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u8a66\u9a13\u3067\u306f\u4ee5\u4e0b\u306e\u7d50\u679c\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u8a66\u9a13\u6bb5\u968e<\/th><th>OS\u4e2d\u592e\u5024<\/th><\/tr><tr><td>Phase 1\uff0830\u4f8b\uff09<\/td><td>6.8\u304b\u6708<\/td><\/tr><tr><td>Phase 2a\uff0858\u4f8b\uff09<\/td><td>14.5\u304b\u6708<\/td><\/tr><tr><td>Phase 2b\uff08101\u4f8b\uff09<\/td><td>15.5\u304b\u6708<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 2b\u306eOS\u4e2d\u592e\u5024\u306f15.5\u304b\u6708\u3067\u300195%\u4fe1\u983c\u533a\u9593\u306f7.6\u304b\u6708\u304b\u3089\u4e0a\u9650\u63a8\u5b9a\u4e0d\u80fd\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001Phase 2b\u306e\u8ffd\u8de1\u671f\u9593\u4e2d\u592e\u5024\u306f11.2\u304b\u6708\u3067\u3042\u308a\u3001\u751f\u5b58\u671f\u9593\u306e\u63a8\u5b9a\u306b\u306f\u672a\u6210\u719f\u306a\u90e8\u5206\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u91cd\u8981\u306a\u306e\u306f\u3001Phase 1\u30012a\u30012b\u306e\u60a3\u8005\u7fa4\u304c\u30e9\u30f3\u30c0\u30e0\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u305f\u3082\u306e\u3067\u306f\u306a\u3044\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001Phase 1\u306e6.8\u304b\u6708\u304b\u3089Phase 2b\u306e15.5\u304b\u6708\u3078\u306e\u5909\u5316\u3092\u3001\u6295\u4e0e\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u8abf\u6574\u306b\u3088\u308b\u751f\u5b58\u671f\u9593\u306e\u5ef6\u9577\u3068\u65ad\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u8005\u3089\u306f\u3001\u5bdb\u89e3\u5f8c\u306e\u6295\u4e0e\u65e5\u6570\u77ed\u7e2e\u3068\u9aa8\u9ac4\u6291\u5236\u306e\u8efd\u6e1b\u304c\u81e8\u5e8a\u8ee2\u5e30\u306e\u6539\u5584\u306b\u5bc4\u4e0e\u3057\u305f\u53ef\u80fd\u6027\u3092\u6307\u6458\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u81e8\u5e8a\u7684\u306b\u8208\u5473\u6df1\u3044\u4eee\u8aac\u3067\u3059\u304c\u3001\u691c\u8a3c\u306b\u306f\u5bfe\u7167\u8a66\u9a13\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"566\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-121.png\" alt=\"ASCERTAIN-V\u8a66\u9a13\u306ePhase 1\u30fb2a\u30fb2b\u306b\u304a\u3051\u308b\u5168\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\" class=\"wp-image-9348\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-121.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-121-400x283.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-121-767x543.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><strong>\u56f34\uff1aASCERTAIN-V\u8a66\u9a13\u306b\u304a\u3051\u308b\u5168\u751f\u5b58\u671f\u9593\uff08OS\uff09\u4e2d\u592e\u5024<\/strong><\/strong>\u3000Phase 1\uff0830\u4f8b\uff09\u3001Phase 2a\uff0858\u4f8b\uff09\u3001Phase 2b\uff08101\u4f8b\uff09\u306b\u304a\u3051\u308b\u5168\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\u306895%\u4fe1\u983c\u533a\u9593\u3092\u793a\u3059\u3002OS\u4e2d\u592e\u5024\u306f\u305d\u308c\u305e\u308c6.8\u304b\u6708\uff0895% CI\uff1a4.3\u201319.5\uff09\u300114.5\u304b\u6708\uff088.1\u201318.2\uff09\u300115.5\u304b\u6708\uff087.6\u2013\u4e0a\u9650\u63a8\u5b9a\u4e0d\u80fd\uff09\u3067\u3042\u3063\u305f\u3002Phase 2b\u306e\u8ffd\u8de1\u671f\u9593\u4e2d\u592e\u5024\u306f11.2\u304b\u6708\u3067\u3042\u308b\u3002\u672c\u8a66\u9a13\u306f\u975e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u3067\u3042\u308a\u3001\u5404Phase\u9593\u306e\u751f\u5b58\u671f\u9593\u306e\u9055\u3044\u3092\u6cbb\u7642\u6cd5\u3084\u6295\u4e0e\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u306e\u52b9\u679c\u3068\u3057\u3066\u76f4\u63a5\u6bd4\u8f03\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u306a\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">8\uff0e\u5fae\u5c0f\u6b8b\u5b58\u75c5\u5909\uff08MRD\uff09\u306e\u9670\u6027\u5316\u3068\u81e8\u5e8a\u7684\u610f\u7fa9<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">AML\u306e\u6cbb\u7642\u3067\u306f\u3001\u901a\u5e38\u306e\u9aa8\u9ac4\u691c\u67fb\u3067\u5b8c\u5168\u5bdb\u89e3\u3068\u5224\u5b9a\u3055\u308c\u3066\u3082\u3001\u5fae\u91cf\u306e\u767d\u8840\u75c5\u7d30\u80de\u304c\u6b8b\u5b58\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3092\u5fae\u5c0f\u6b8b\u5b58\u75c5\u5909\u3001\u3042\u308b\u3044\u306f\u6e2c\u5b9a\u53ef\u80fd\u6b8b\u5b58\u75c5\u5909\uff08Measurable Residual Disease\uff1aMRD\uff09\u3068\u547c\u3073\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">MRD\u306fAML\u306e\u518d\u767a\u30ea\u30b9\u30af\u3092\u8a55\u4fa1\u3059\u308b\u91cd\u8981\u306a\u6307\u6a19\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ASCERTAIN-V\u8a66\u9a13\u306ePhase 2b\u3067\u306f\u3001CR\u3001CRi\u307e\u305f\u306fCRh\u304c\u5f97\u3089\u308c\u305f64\u4f8b\u306e\u3046\u3061\u300149\u4f8b\u3067MRD\u304c\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e49\u4f8b\u306e\u3046\u306127\u4f8b\uff0855%\uff09\u3067\u3001\u3044\u305a\u308c\u304b\u306e\u8a55\u4fa1\u6642\u70b9\u306b\u304a\u3044\u3066MRD\u9670\u6027\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">MRD\u9670\u6027\u306e\u5b9a\u7fa9\u306f\u3001\u591a\u9805\u76ee\u30d5\u30ed\u30fc\u30b5\u30a4\u30c8\u30e1\u30c8\u30ea\u30fc\u306b\u3088\u308b10\u207b\u2074\u672a\u6e80\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u63a2\u7d22\u7684\u89e3\u6790\u3067\u306f\u3001MRD\u9670\u6027\u3068\u306a\u3063\u305f\u594f\u52b9\u60a3\u8005\u306e1\u5e74\u751f\u5b58\u5272\u5408\u306f92%\u3068\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001MRD\u6e2c\u5b9a\u306e\u65b9\u6cd5\u3084\u6642\u70b9\u306f\u6a19\u6e96\u5316\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u8a55\u4fa1\u3055\u308c\u305f\u60a3\u8005\u3082\u9078\u629e\u3055\u308c\u305f\u96c6\u56e3\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001MRD\u9670\u6027\u5316\u304c\u751f\u5b58\u671f\u9593\u3092\u6539\u5584\u3057\u305f\u56e0\u679c\u95a2\u4fc2\u307e\u3067\u793a\u3059\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">9\uff0e\u5b89\u5168\u6027\uff5c\u5b8c\u5168\u7d4c\u53e3\u6cbb\u7642\u3067\u3082\u91cd\u5ea6\u306e\u9aa8\u9ac4\u6291\u5236\u306f\u91cd\u8981<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d4c\u53e3\u6cbb\u7642\u3068\u3044\u3046\u3068\u3001\u70b9\u6ef4\u6cbb\u7642\u3088\u308a\u526f\u4f5c\u7528\u304c\u5c11\u306a\u3044\u5370\u8c61\u3092\u53d7\u3051\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u672c\u8a66\u9a13\u3067\u306f\u91cd\u5ea6\u306e\u9aa8\u9ac4\u6291\u5236\u304c\u9ad8\u983b\u5ea6\u3067\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 2b\u306b\u304a\u3051\u308b\u4e3b\u306aGrade 3\u4ee5\u4e0a\u306e\u6cbb\u7642\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u6709\u5bb3\u4e8b\u8c61<\/th><th class=\"has-text-align-right\" data-align=\"right\">\u983b\u5ea6<\/th><\/tr><tr><td>\u8ca7\u8840<\/td><td class=\"has-text-align-right\" data-align=\"right\">30%<\/td><\/tr><tr><td>\u597d\u4e2d\u7403\u6e1b\u5c11<\/td><td class=\"has-text-align-right\" data-align=\"right\">26%<\/td><\/tr><tr><td>\u767a\u71b1\u6027\u597d\u4e2d\u7403\u6e1b\u5c11\u75c7<\/td><td class=\"has-text-align-right\" data-align=\"right\">25%<\/td><\/tr><tr><td>\u8840\u5c0f\u677f\u6570\u6e1b\u5c11<\/td><td class=\"has-text-align-right\" data-align=\"right\">25%<\/td><\/tr><tr><td>\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7<\/td><td class=\"has-text-align-right\" data-align=\"right\">20%<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Grade 3\u4ee5\u4e0a\u306e\u6cbb\u7642\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\u5168\u4f53\u306f72%\u306b\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u306f84%\u3001\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u6cbb\u7642\u4e2d\u6b62\u306f9%\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001Phase 2b\u306b\u304a\u3051\u308b\u6b7b\u4ea1\u7387\u306f30\u65e5\u30673%\u300160\u65e5\u306710%\u3067\u3057\u305f\u3002\u3053\u308c\u306f\u4e00\u5b9a\u671f\u9593\u5185\u306e\u5168\u6b7b\u56e0\u6b7b\u4ea1\u7387\u3067\u3042\u308a\u3001\u3059\u3079\u3066\u304c\u6cbb\u7642\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u305f\u6b7b\u4ea1\u3092\u610f\u5473\u3059\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u6cbb\u7642\u306b\u304a\u3044\u3066\u306f\u3001\u767a\u71b1\u6027\u597d\u4e2d\u7403\u6e1b\u5c11\u75c7\u3001\u91cd\u75c7\u611f\u67d3\u75c7\u3001\u51fa\u8840\u306a\u3069\u3078\u306e\u5bfe\u5fdc\u304c\u6975\u3081\u3066\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d4c\u53e3\u85ac\u306e\u307f\u3067\u6cbb\u7642\u3067\u304d\u308b\u3053\u3068\u306f\u3001\u533b\u5b66\u7684\u7ba1\u7406\u3092\u4e0d\u8981\u306b\u3059\u308b\u3053\u3068\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6cbb\u7642\u521d\u671f\u306b\u306f\u5165\u9662\u7ba1\u7406\u3092\u691c\u8a0e\u3059\u3079\u304d\u5834\u5408\u3082\u3042\u308a\u3001\u7d99\u7d9a\u7684\u306a\u8840\u7b97\u6e2c\u5b9a\u3001\u9aa8\u9ac4\u8a55\u4fa1\u3001\u611f\u67d3\u4e88\u9632\u3001\u8f38\u8840\u306a\u3069\u306e\u652f\u6301\u7642\u6cd5\u304c\u6b20\u304b\u305b\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"566\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-122.png\" alt=\"\u5b8c\u5168\u7d4c\u53e3AML\u6cbb\u7642\u306e\u91cd\u5ea6\u6709\u5bb3\u4e8b\u8c61\u3068\u767a\u751f\u983b\u5ea6\" class=\"wp-image-9349\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-122.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-122-400x283.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-122-767x543.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f35\uff1aGrade 3\u4ee5\u4e0a\u306e\u9aa8\u9ac4\u6291\u5236<\/strong>\u3000Phase 2b\uff08101\u4f8b\uff09\u306b\u304a\u3051\u308bGrade 3\u4ee5\u4e0a\u306e\u4e3b\u306a\u6cbb\u7642\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\u3002\u8ca7\u884030%\u3001\u597d\u4e2d\u7403\u6e1b\u5c1126%\u3001\u767a\u71b1\u6027\u597d\u4e2d\u7403\u6e1b\u5c11\u75c725%\u3001\u8840\u5c0f\u677f\u6570\u6e1b\u5c1125%\u3001\u8840\u5c0f\u677f\u6e1b\u5c11\u75c720%\u3092\u6a2a\u68d2\u30b0\u30e9\u30d5\u3067\u793a\u3059\u3002\u540c\u4e00\u60a3\u8005\u306b\u8907\u6570\u306e\u4e8b\u8c61\u304c\u751f\u3058\u5f97\u308b\u305f\u3081\u3001\u5404\u983b\u5ea6\u306e\u5408\u8a08\u306f100%\u306b\u306a\u3089\u306a\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">10\uff0e\u85ac\u7269\u9593\u76f8\u4e92\u4f5c\u7528\u3068\u6297\u771f\u83cc\u85ac\u4f75\u7528\u6642\u306e\u6ce8\u610f\u70b9<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u7814\u7a76\u3067\u306f\u3001\u30c7\u30b7\u30bf\u30d3\u30f3\u30fb\u30bb\u30c0\u30ba\u30ea\u30b8\u30f3\u3068\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u306e\u4f75\u7528\u306b\u3088\u3063\u3066\u3001\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u306a\u85ac\u7269\u52d5\u614b\u5b66\u7684\u76f8\u4e92\u4f5c\u7528\u306f\u78ba\u8a8d\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u306f\u4e21\u85ac\u5264\u9593\u306e\u85ac\u7269\u52d5\u614b\u306b\u3064\u3044\u3066\u306e\u7d50\u679c\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u306fCYP3A\u3067\u4ee3\u8b1d\u3055\u308c\u308b\u305f\u3081\u3001\u30dd\u30b5\u30b3\u30ca\u30be\u30fc\u30eb\u306a\u3069\u306e\u30a2\u30be\u30fc\u30eb\u7cfb\u6297\u771f\u83cc\u85ac\u3068\u306e\u4f75\u7528\u3067\u306f\u8840\u4e2d\u6fc3\u5ea6\u304c\u4e0a\u6607\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u4f75\u7528\u85ac\u306b\u5fdc\u3058\u3066\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u306e\u7528\u91cf\u3092\u9069\u5207\u306b\u8abf\u6574\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 2b\u3067\u306f82%\u306e\u60a3\u8005\u3055\u3093\u306b\u30a2\u30be\u30fc\u30eb\u7cfb\u6297\u771f\u83cc\u85ac\u306b\u3088\u308b\u4e88\u9632\u6295\u4e0e\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u300144%\u3067G-CSF\u304c\u4f7f\u7528\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5b8c\u5168\u7d4c\u53e3\u7642\u6cd5\u306e\u5b9f\u65bd\u306b\u306f\u3001\u6297\u767d\u8840\u75c5\u85ac\u305d\u306e\u3082\u306e\u3060\u3051\u3067\u306a\u304f\u3001\u611f\u67d3\u4e88\u9632\u3001\u652f\u6301\u7642\u6cd5\u3001\u76f8\u4e92\u4f5c\u7528\u7ba1\u7406\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">11\uff0e\u3053\u306e\u7814\u7a76\u306e\u9650\u754c\uff5c\u5f93\u6765\u6cbb\u7642\u3088\u308a\u512a\u308c\u3066\u3044\u308b\u3068\u306f\u307e\u3060\u8a00\u3048\u306a\u3044<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">ASCERTAIN-V\u8a66\u9a13\u306f\u3001AML\u306e\u6cbb\u7642\u9078\u629e\u80a2\u3092\u62e1\u5927\u3059\u308b\u3046\u3048\u3067\u91cd\u8981\u306a\u7814\u7a76\u3067\u3059\u304c\u3001\u89e3\u91c8\u4e0a\u306e\u9650\u754c\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">11-1\uff0e\u975e\u30e9\u30f3\u30c0\u30e0\u5316\u30fb\u5358\u7fa4\u8a66\u9a13\u3067\u3042\u308b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u7814\u7a76\u306b\u306f\u540c\u6642\u5bfe\u7167\u7fa4\u304c\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001\u5b8c\u5168\u7d4c\u53e3\u7642\u6cd5\u304c\u30a2\u30b6\u30b7\u30c1\u30b8\u30f3\uff0b\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u306a\u3069\u306e\u6a19\u6e96\u6cbb\u7642\u3068\u6bd4\u8f03\u3057\u3066\u3001\u6709\u52b9\u6027\u3084\u5b89\u5168\u6027\u306e\u9762\u3067\u540c\u7b49\u307e\u305f\u306f\u512a\u308c\u3066\u3044\u308b\u3068\u306f\u7d50\u8ad6\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6b74\u53f2\u7684\u5bfe\u7167\u3068\u306e\u6bd4\u8f03\u306b\u306f\u3001\u60a3\u8005\u80cc\u666f\u3001\u907a\u4f1d\u5b50\u5909\u7570\u3001\u6cbb\u7642\u4e2d\u65ad\u57fa\u6e96\u3001\u652f\u6301\u7642\u6cd5\u306a\u3069\u306e\u9055\u3044\u304c\u5f71\u97ff\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">11-2\uff0e\u751f\u5b58\u671f\u9593\u306e\u8ffd\u8de1\u304c\u5341\u5206\u306b\u6210\u719f\u3057\u3066\u3044\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 2b\u306e\u8ffd\u8de1\u671f\u9593\u4e2d\u592e\u5024\u306f11.2\u304b\u6708\u3067\u3042\u308a\u3001\u9577\u671f\u751f\u5b58\u671f\u9593\u3001\u518d\u767a\u3001\u6cbb\u7642\u7d99\u7d9a\u6027\u306a\u3069\u306b\u3064\u3044\u3066\u306f\u8ffd\u52a0\u691c\u8a3c\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">11-3\uff0e\u751f\u6d3b\u306e\u8cea\u3084\u901a\u9662\u8ca0\u62c5\u3092\u76f4\u63a5\u8a55\u4fa1\u3057\u3066\u3044\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d4c\u53e3\u6cbb\u7642\u306b\u3088\u308b\u901a\u9662\u8ca0\u62c5\u306e\u8efd\u6e1b\u306f\u5408\u7406\u7684\u306b\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u672c\u8a66\u9a13\u3067\u306f\u60a3\u8005\u5831\u544a\u306b\u3088\u308b\u751f\u6d3b\u306e\u8cea\uff08QOL\uff09\u3084\u533b\u7642\u8cc7\u6e90\u306e\u5229\u7528\u306b\u3064\u3044\u3066\u3001\u76f4\u63a5\u7684\u306a\u8a55\u4fa1\u306f\u884c\u308f\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u7d4c\u53e3\u5316\u306b\u3088\u3063\u3066QOL\u304c\u6539\u5584\u3057\u305f\u3068\u65ad\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">11-4\uff0e\u6295\u4e0e\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u77ed\u7e2e\u306e\u52b9\u679c\u306f\u63a2\u7d22\u7684\u3067\u3042\u308b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Phase 2b\u3067\u306f\u3001\u9aa8\u9ac4\u82bd\u7403\u306e\u6d88\u5931\u5f8c\u306b\u6295\u4e0e\u65e5\u6570\u3092\u8abf\u6574\u3059\u308b\u6226\u7565\u304c\u5c0e\u5165\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u77ed\u7e2e\u7fa4\u3068\u975e\u77ed\u7e2e\u7fa4\u3092\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u3057\u305f\u8a66\u9a13\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9aa8\u9ac4\u6291\u5236\u306e\u7ba1\u7406\u4e0a\u6709\u7528\u3068\u8003\u3048\u3089\u308c\u308b\u4e00\u65b9\u3001\u6700\u9069\u306a\u6295\u4e0e\u671f\u9593\u3084\u751f\u5b58\u8ee2\u5e30\u3078\u306e\u72ec\u7acb\u3057\u305f\u52b9\u679c\u306f\u672a\u78ba\u5b9a\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">12\uff0e2026\u5e74\u306e\u81e8\u5e8a\u7684\u610f\u7fa9\uff5cAML\u6cbb\u7642\u306f\u300c\u3059\u3079\u3066\u98f2\u307f\u85ac\u300d\u306e\u6642\u4ee3\u3078\u9032\u3080\u306e\u304b\uff1f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u7814\u7a76\u306e\u610f\u7fa9\u306f\u3001\u5358\u306b\u65b0\u3057\u3044\u85ac\u5264\u306e\u7d44\u307f\u5408\u308f\u305b\u3092\u8a66\u3057\u305f\u3053\u3068\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3059\u3067\u306b\u78ba\u7acb\u3055\u308c\u3066\u3044\u308b\u4f4e\u30e1\u30c1\u30eb\u5316\u85ac\u3068BCL-2\u963b\u5bb3\u85ac\u3068\u3044\u3046\u6cbb\u7642\u6226\u7565\u3092\u3001\u3059\u3079\u3066\u7d4c\u53e3\u85ac\u3067\u5b9f\u65bd\u3067\u304d\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u305f\u70b9\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u9f62AML\u60a3\u8005\u3055\u3093\u3067\u306f\u3001\u6297\u767d\u8840\u75c5\u52b9\u679c\u3068\u3068\u3082\u306b\u3001\u901a\u9662\u8ca0\u62c5\u3001\u65e5\u5e38\u751f\u6d3b\u3001\u4ecb\u8b77\u8005\u306e\u8ca0\u62c5\u306a\u3069\u3082\u6cbb\u7642\u9078\u629e\u306b\u5f71\u97ff\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5b8c\u5168\u7d4c\u53e3\u5316\u306f\u3001\u3053\u308c\u3089\u306e\u8ab2\u984c\u3092\u6539\u5584\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3067\u3001\u7d4c\u53e3\u5316\u306b\u3088\u3063\u3066\u9aa8\u9ac4\u6291\u5236\u3084\u611f\u67d3\u75c7\u306e\u5371\u967a\u304c\u306a\u304f\u306a\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001AML\u306f\u907a\u4f1d\u5b50\u7570\u5e38\u306b\u3088\u3063\u3066\u75c5\u614b\u3084\u6cbb\u7642\u53cd\u5fdc\u6027\u304c\u7570\u306a\u308a\u3001FLT3\u963b\u5bb3\u85ac\u3001IDH\u963b\u5bb3\u85ac\u306a\u3069\u306e\u5206\u5b50\u6a19\u7684\u6cbb\u7642\u304c\u691c\u8a0e\u3055\u308c\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5b8c\u5168\u7d4c\u53e3\u5316\u3068\u3044\u3046\u5229\u70b9\u3060\u3051\u3067\u3001\u60a3\u8005\u3055\u3093\u3054\u3068\u306e\u6700\u9069\u6cbb\u7642\u3092\u4e00\u5f8b\u306b\u6c7a\u3081\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u672c\u8a66\u9a13\u304c\u793a\u3057\u305f\u306e\u306f\u3001\u5f37\u529b\u306a\u5316\u5b66\u7642\u6cd5\u304c\u96e3\u3057\u3044AML\u60a3\u8005\u3055\u3093\u306b\u5bfe\u3057\u3066\u5b8c\u5168\u7d4c\u53e3\u7642\u6cd5\u304c\u6709\u671b\u306a\u6cbb\u7642\u9078\u629e\u80a2\u3068\u306a\u308a\u5f97\u308b\u3053\u3068\u3067\u3059\u3002\u3059\u3079\u3066\u306eAML\u60a3\u8005\u3055\u3093\u3067\u5f93\u6765\u6cbb\u7642\u3092\u7f6e\u304d\u63db\u3048\u3089\u308c\u308b\u3068\u8a3c\u660e\u3057\u305f\u7814\u7a76\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2026\u5e745\u6708\u3001\u7c73\u56fdFDA\u304c\u5b8c\u5168\u7d4c\u53e3\u4f75\u7528\u7642\u6cd5\u3092\u627f\u8a8d<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">ASCERTAIN-V\u8a66\u9a13\u306e\u7d50\u679c\u3092\u53d7\u3051\u3066\u3001\u7c73\u56fd\u98df\u54c1\u533b\u85ac\u54c1\u5c40\uff08FDA\uff09\u306f2026\u5e745\u670813\u65e5\u300175\u6b73\u4ee5\u4e0a\u3001\u307e\u305f\u306f\u4f75\u5b58\u75be\u60a3\u306b\u3088\u3063\u3066\u5f37\u529b\u306a\u5bdb\u89e3\u5c0e\u5165\u5316\u5b66\u7642\u6cd5\u304c\u9069\u3055\u306a\u3044\u65b0\u898f\u8a3a\u65adAML\u6210\u4eba\u60a3\u8005\u306b\u5bfe\u3057\u3001\u30c7\u30b7\u30bf\u30d3\u30f3\u30fb\u30bb\u30c0\u30ba\u30ea\u30b8\u30f3\uff08INQOVI\uff09\u3068\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u306e\u4f75\u7528\u7642\u6cd5\u3092\u627f\u8a8d\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u5b8c\u5168\u7d4c\u53e3\u6cbb\u7642\u304c\u3001\u81e8\u5e8a\u7814\u7a76\u306e\u6bb5\u968e\u304b\u3089\u5b9f\u969b\u306e\u6cbb\u7642\u9078\u629e\u80a2\u3078\u9032\u3093\u3060\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u7c73\u56fd\u3067\u306e\u627f\u8a8d\u306f\u65e5\u672c\u56fd\u5185\u3067\u306e\u627f\u8a8d\u3092\u610f\u5473\u3057\u307e\u305b\u3093\u3002\u56fd\u5185\u3067\u306e\u4f7f\u7528\u306b\u969b\u3057\u3066\u306f\u3001\u6700\u65b0\u306e\u627f\u8a8d\u72b6\u6cc1\u30fb\u6dfb\u4ed8\u6587\u66f8\u30fb\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3092\u78ba\u8a8d\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u7c73\u56fdFDA\u516c\u5f0f\u767a\u8868<\/strong>\uff1a<a href=\"https:\/\/www.fda.gov\/drugs\/resources-information-approved-drugs\/fda-approves-oral-combination-decitabine-and-cedazuridine-tablets-venetoclax-newly-diagnosed-acute?utm_source=chatgpt.com\">FDA Approves Oral Combination of Decitabine and Cedazuridine with Venetoclax for Newly Diagnosed AML<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">13\uff0e\u8ca7\u8840\u30fb\u767a\u71b1\u30fb\u51fa\u8840\u50be\u5411\u304c\u7d9a\u304f\u5834\u5408\u306f\u65e9\u671f\u306e\u8a55\u4fa1\u304c\u91cd\u8981<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u6025\u6027\u9aa8\u9ac4\u6027\u767d\u8840\u75c5\u3067\u306f\u3001\u8ca7\u8840\u3001\u767a\u71b1\u3001\u51fa\u8840\u50be\u5411\u306a\u3069\u304c\u6700\u521d\u306e\u75c7\u72b6\u3068\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u3053\u308c\u3089\u306e\u75c7\u72b6\u306fAML\u4ee5\u5916\u306e\u591a\u304f\u306e\u75c5\u6c17\u3067\u3082\u51fa\u73fe\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u539f\u56e0\u306e\u5206\u304b\u3089\u306a\u3044\u8ca7\u8840\u3001\u767d\u8840\u7403\u30fb\u8840\u5c0f\u677f\u306e\u7570\u5e38\u3001\u9577\u5f15\u304f\u767a\u71b1\u3001\u5f37\u3044\u5026\u6020\u611f\u306a\u3069\u304c\u3042\u308b\u5834\u5408\u306b\u306f\u3001\u8840\u6db2\u691c\u67fb\u306b\u3088\u308b\u8a55\u4fa1\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u67cf\u4e94\u5473\u6b6f\u79d1\u5185\u79d1\u30ea\u30a6\u30de\u30c1\u30af\u30ea\u30cb\u30c3\u30af\u3067\u306f\u3001\u7dcf\u5408\u5185\u79d1\u306e\u7acb\u5834\u304b\u3089\u3001\u8840\u7b97\u7570\u5e38\u3084\u539f\u56e0\u4e0d\u660e\u306e\u5168\u8eab\u75c7\u72b6\u306b\u3064\u3044\u3066\u521d\u671f\u8a55\u4fa1\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6025\u6027\u767d\u8840\u75c5\u306a\u3069\u306e\u8840\u6db2\u75be\u60a3\u304c\u7591\u308f\u308c\u308b\u5834\u5408\u306b\u306f\u3001\u901f\u3084\u304b\u306b\u8840\u6db2\u5185\u79d1\u306e\u3042\u308b\u5c02\u9580\u533b\u7642\u6a5f\u95a2\u3078\u7d39\u4ecb\u3057\u3001\u7cbe\u5bc6\u691c\u67fb\u30fb\u5c02\u9580\u6cbb\u7642\u306b\u3064\u306a\u3052\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u306a\u304a\u3001\u672c\u8a18\u4e8b\u3067\u7d39\u4ecb\u3057\u305fAML\u306b\u5bfe\u3059\u308b\u7d4c\u53e3\u6297\u767d\u8840\u75c5\u7642\u6cd5\u306f\u3001\u8840\u6db2\u5185\u79d1\u5c02\u9580\u65bd\u8a2d\u3067\u306e\u7ba1\u7406\u3092\u524d\u63d0\u3068\u3057\u305f\u6cbb\u7642\u3067\u3042\u308a\u3001\u5f53\u9662\u3067\u306e\u6cbb\u7642\u63d0\u4f9b\u3092\u610f\u5473\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">14\uff0e\u307e\u3068\u3081<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">ASCERTAIN-V\u8a66\u9a13\u306f\u3001\u5f37\u529b\u306a\u5316\u5b66\u7642\u6cd5\u304c\u9069\u3055\u306a\u3044\u65b0\u898f\u8a3a\u65adAML\u60a3\u8005\u306b\u5bfe\u3059\u308b\u3001\u30c7\u30b7\u30bf\u30d3\u30f3\u30fb\u30bb\u30c0\u30ba\u30ea\u30b8\u30f3\uff0b\u30d9\u30cd\u30c8\u30af\u30e9\u30af\u30b9\u306e\u5b8c\u5168\u7d4c\u53e3\u7642\u6cd5\u3092\u691c\u8a0e\u3057\u305f\u7b2c1\uff5e2\u76f8\u8a66\u9a13\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u8981\u306a\u7d50\u679c\u3068\u3057\u3066\u3001Phase 2b\u306e\u5b8c\u5168\u5bdb\u89e3\u7387\u306f47%\u3001CR\uff0bCRi\u7387\u306f63%\u3001\u5168\u751f\u5b58\u671f\u9593\u4e2d\u592e\u5024\u306f15.5\u304b\u6708\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u4eca\u5f8c\u306e\u8ab2\u984c\u306f\u3001\u6a19\u6e96\u7684\u306a\u6ce8\u5c04\u30fb\u70b9\u6ef4\u4f75\u7528\u7642\u6cd5\u3068\u306e\u76f4\u63a5\u6bd4\u8f03\u3001\u9577\u671f\u751f\u5b58\u30fb\u518d\u767a\u306b\u95a2\u3059\u308b\u8a55\u4fa1\u3001\u305d\u3057\u3066\u60a3\u8005\u3055\u3093\u306e\u751f\u6d3b\u306e\u8cea\u3084\u901a\u9662\u8ca0\u62c5\u304c\u3069\u306e\u7a0b\u5ea6\u6539\u5584\u3059\u308b\u304b\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u5b8c\u5168\u7d4c\u53e3\u7642\u6cd5\u306fAML\u6cbb\u7642\u306e\u5229\u4fbf\u6027\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u306e\u81e8\u5e8a\u7684\u4fa1\u5024\u306f\u6709\u52b9\u6027\u30fb\u5b89\u5168\u6027\u30fb\u60a3\u8005\u8ca0\u62c5\u3092\u7dcf\u5408\u3057\u3066\u5224\u65ad\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>\u539f\u8457\u8ad6\u6587<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Roboz GJ, Zeidan AM, Mannis GN, et al. All-Oral Treatment of Newly Diagnosed Acute Myeloid Leukemia. <em>N Engl J Med.<\/em> 2026;394:2107\u20132116.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">DOI: <a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2510223\">https:\/\/doi.org\/10.1056\/NEJMoa2510223<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u81e8\u5e8a\u8a66\u9a13\u767b\u9332\uff1aASCERTAIN-V\uff08NCT04657081\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u95a2\u9023\u3059\u308b\u4e3b\u8981\u6587\u732e<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">DiNardo CD, Jonas BA, Pullarkat V, et al. Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia. <em>N Engl J Med.<\/em> 2020;383:617\u2013629.<\/p>\n<\/blockquote>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">15. \u3042\u308f\u305b\u3066\u8aad\u307f\u305f\u3044\u95a2\u9023\u8a18\u4e8b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u2460 <a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-1403\/\"><strong>VEXAS\u75c7\u5019\u7fa4\u306b\u3064\u3044\u3066\u306e\u6700\u65b0\u898b\u89e3<\/strong><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9aa8\u9ac4\u7570\u5f62\u6210\u75c7\u5019\u7fa4\u3068\u306e\u95a2\u9023\u3084\u3001\u30a2\u30b6\u30b7\u30c1\u30b8\u30f3\u30fb\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\u306a\u3069\u306e\u6cbb\u7642\u6226\u7565\u3092\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002AML\u306e\u80cc\u666f\u306b\u3042\u308b\u9020\u8840\u7570\u5e38\u3092\u7406\u89e3\u3059\u308b\u3046\u3048\u3067\u3082\u53c2\u8003\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u2461 <a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-2208\/\"><strong>\u80ba\u30e0\u30b3\u30fc\u30eb\u75c7\uff1a\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\u5f8c\u306e\u91cd\u75c7\u771f\u83cc\u611f\u67d3\u75c7<\/strong><\/a><\/p>\n\n\n\n<p 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