{"id":9359,"date":"2026-10-19T16:23:48","date_gmt":"2026-10-19T07:23:48","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=9359"},"modified":"2026-10-19T16:50:23","modified_gmt":"2026-10-19T07:50:23","slug":"cerebral-amyloid-angiopathy-caa","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/cerebral-amyloid-angiopathy-caa\/","title":{"rendered":"\u8133\u30a2\u30df\u30ed\u30a4\u30c9\u30a2\u30f3\u30ae\u30aa\u30d1\u30c1\u30fc\uff08CAA\uff09\u3068\u306f\uff1f\u8133\u51fa\u8840\u30fb\u8a8d\u77e5\u75c7\u30fbMRI\u8a3a\u65ad\u3068\u6cbb\u7642"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u3010\u8133\u795e\u7d4c\u5185\u79d1\u30fb\u8133\u5352\u4e2d\u533b\u5b66\u30fb\u8a8d\u77e5\u75c7\u533b\u5b66\u30fb\u795e\u7d4c\u514d\u75ab\u5b66\u3011\u8133\u30a2\u30df\u30ed\u30a4\u30c9\u30a2\u30f3\u30ae\u30aa\u30d1\u30c1\u30fc\uff08Cerebral Amyloid Angiopathy\uff1aCAA\uff09\u306e\u75c5\u614b\u3001\u8133\u8449\u51fa\u8840\u306e\u518d\u767a\u30ea\u30b9\u30af\u3001Boston criteria version 2.0\u306b\u3088\u308b\u753b\u50cf\u8a3a\u65ad\u3001\u6297\u8840\u6813\u7642\u6cd5\u306e\u5224\u65ad\u3001\u304a\u3088\u3073CAA\u95a2\u9023\u708e\u75c7\u3068\u30a2\u30df\u30ed\u30a4\u30c9\u95a2\u9023\u753b\u50cf\u7570\u5e38\uff08ARIA\uff09<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u8133\u306e\u8840\u7ba1\u306b\u30a2\u30df\u30ed\u30a4\u30c9\u304c\u305f\u307e\u308b\u3053\u3068\u3067\u3001\u51fa\u8840\u3084\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u5f15\u304d\u8d77\u3053\u3059\u75c5\u6c17<\/h3>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u4e00\u90e8\u306e\u60a3\u8005\u3055\u3093\u3067\u306f\u8133\u8840\u7ba1\u306b\u6c88\u7740\u3057\u305f\u30a2\u30df\u30ed\u30a4\u30c9\u306b\u5bfe\u3057\u3066\u708e\u75c7\u304c\u8d77\u3053\u308a\u3001\u982d\u75db\u3001\u3051\u3044\u308c\u3093\u3001\u610f\u8b58\u3084\u8a8d\u77e5\u6a5f\u80fd\u306e\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u75c5\u614b\u3067\u306f\u514d\u75ab\u6291\u5236\u6cbb\u7642\u304c\u6709\u52b9\u3068\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2026\u5e74\u306eNEJM\u7dcf\u8aac\u3092\u57fa\u306b\u3001CAA\u306e\u75c5\u614b\u3001\u8a3a\u65ad\u3001\u518d\u51fa\u8840\u4e88\u9632\u3001\u305d\u3057\u3066\u4eca\u5f8c\u306e\u6cbb\u7642\u958b\u767a\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1\uff0e\u8133\u30a2\u30df\u30ed\u30a4\u30c9\u30a2\u30f3\u30ae\u30aa\u30d1\u30c1\u30fc\uff08CAA\uff09\u3068\u306f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u30a2\u30df\u30ed\u30a4\u30c9\u30a2\u30f3\u30ae\u30aa\u30d1\u30c1\u30fc\uff08Cerebral Amyloid Angiopathy\uff1aCAA\uff09\u306f\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\uff08amyloid-\u03b2\uff1aA\u03b2\uff09\u304c\u8133\u306e\u5c0f\u8840\u7ba1\u58c1\u306b\u6c88\u7740\u3059\u308b\u75be\u60a3\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u306e\u306f\u3001\u8133\u8868\u3092\u8986\u3046\u8edf\u819c\u30fb\u304f\u3082\u819c\u9818\u57df\u306e\u8840\u7ba1\uff08leptomeningeal vessels\uff09\u3068\u3001\u5927\u8133\u76ae\u8cea\u306e\u7d30\u52d5\u8108\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u304c\u9032\u884c\u3059\u308b\u3068\u3001\u8840\u7ba1\u58c1\u306e\u5e73\u6ed1\u7b4b\u7d30\u80de\u304c\u5931\u308f\u308c\u3001\u8840\u7ba1\u69cb\u9020\u304c\u7834\u7dbb\u3057\u3001\u8133\u51fa\u8840\u3092\u8d77\u3053\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306f\u5358\u306a\u308b\u8133\u51fa\u8840\u306e\u539f\u56e0\u3067\u306f\u306a\u304f\u3001\u8133\u5c0f\u8840\u7ba1\u306e\u6a5f\u80fd\u969c\u5bb3\u3092\u4ecb\u3057\u3066\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u306b\u3082\u95a2\u4fc2\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3068\u306e\u9055\u3044<\/h3>\n\n\n\n<p 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class=\"has-fixed-layout\"><tbody><tr><th>\u9805\u76ee<\/th><th>CAA<\/th><th>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5<\/th><\/tr><tr><td>\u4e3b\u306aA\u03b2\u6c88\u7740\u90e8\u4f4d<\/td><td>\u8133\u306e\u5c0f\u8840\u7ba1\u58c1<\/td><td>\u8133\u5b9f\u8cea\u306e\u8001\u4eba\u6591<\/td><\/tr><tr><td>\u512a\u4f4d\u306aA\u03b2\u5206\u5b50\u7a2e<\/td><td>A\u03b240<\/td><td>A\u03b242<\/td><\/tr><tr><td>\u7279\u5fb4\u7684\u306a\u75c5\u614b<\/td><td>\u8840\u7ba1\u58c1\u969c\u5bb3\u30fb\u51fa\u8840<\/td><td>\u795e\u7d4c\u5909\u6027\u30fb\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3<\/td><\/tr><tr><td>\u4e3b\u306a\u81e8\u5e8a\u75c7\u72b6<\/td><td>\u8133\u51fa\u8840\u3001\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3001\u4e00\u904e\u6027\u795e\u7d4c\u75c7\u72b6<\/td><td>\u8a18\u61b6\u969c\u5bb3\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b<\/td><\/tr><tr><td>\u4e21\u8005\u306e\u95a2\u4fc2<\/td><td>\u4f75\u5b58\u304c\u591a\u3044<\/td><td>\u4f75\u5b58\u304c\u591a\u3044<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u306f\u75c5\u614b\u4e0a\u306e\u5178\u578b\u7684\u306a\u9055\u3044\u3067\u3042\u308a\u3001\u3069\u3061\u3089\u304b\u4e00\u65b9\u306e\u75c5\u6c17\u3067\u3057\u304b\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u304c\u8d77\u3053\u3089\u306a\u3044\u3001\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306f\u5171\u901a\u3059\u308bA\u03b2\u4ee3\u8b1d\u7570\u5e38\u3084APOE\u907a\u4f1d\u5b50\u306a\u3069\u306e\u80cc\u666f\u3092\u6301\u3061\u3001\u540c\u3058\u60a3\u8005\u3055\u3093\u306b\u4f75\u5b58\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2\uff0eCAA\u306f\u3069\u306e\u7a0b\u5ea6\u307f\u3089\u308c\u308b\u75c5\u6c17\u306a\u306e\u304b<\/h2>\n\n\n\n<p 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class=\"wp-block-paragraph\">CAA\u306e\u75c5\u614b\u306f\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u6c88\u7740\u306b\u3088\u308b\u5358\u7d14\u306a\u8840\u7ba1\u306e\u72ed\u7a84\u3060\u3051\u3067\u306f\u8aac\u660e\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c5\u7406\u5b66\u7684\u306b\u306f\u3001\u6b21\u306e\u3088\u3046\u306a\u6bb5\u968e\u7684\u5909\u5316\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u8efd\u75c7CAA\uff1a\u8840\u7ba1\u58c1\u3078\u306e\u90e8\u5206\u7684\u306aA\u03b2\u6c88\u7740<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5c0f\u52d5\u8108\u58c1\u306e\u4e00\u90e8\u306bA\u03b2\u304c\u6c88\u7740\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u6bb5\u968e\u3067\u306f\u3001\u8840\u7ba1\u58c1\u306e\u5e73\u6ed1\u7b4b\u7d30\u80de\u3084\u8840\u7ba1\u69cb\u9020\u304c\u6bd4\u8f03\u7684\u4fdd\u305f\u308c\u3066\u3044\u308b\u90e8\u5206\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u4e2d\u7b49\u75c7CAA\uff1a\u8840\u7ba1\u5e73\u6ed1\u7b4b\u306e\u6d88\u5931\u3068A\u03b2\u306b\u3088\u308b\u7f6e\u63db<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u7ba1\u58c1\u306bA\u03b2\u304c\u5e83\u7bc4\u56f2\u306b\u6c88\u7740\u3059\u308b\u3068\u3001\u4e2d\u819c\u306e\u5e73\u6ed1\u7b4b\u7d30\u80de\u304c\u5931\u308f\u308c\u3001\u8840\u7ba1\u58c1\u306e\u69cb\u9020\u304c\u5909\u5316\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u7ba1\u304c\u751f\u7406\u7684\u523a\u6fc0\u306b\u53cd\u5fdc\u3057\u3066\u62e1\u5f35\u30fb\u53ce\u7e2e\u3059\u308b\u6a5f\u80fd\u3082\u969c\u5bb3\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u91cd\u75c7CAA\uff1a\u8840\u7ba1\u58c1\u306e\u65ad\u88c2\u3068\u51fa\u8840<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u9032\u884c\u3059\u308b\u3068\u8840\u7ba1\u58c1\u306b\u4e80\u88c2\u3084\u5c64\u72b6\u306e\u5206\u96e2\u304c\u751f\u3058\u3001\u6b63\u5e38\u306a\u8840\u7ba1\u69cb\u9020\u304c\u4fdd\u3066\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u6db2\u8133\u95a2\u9580\uff08BBB\uff09\u306e\u900f\u904e\u6027\u4ea2\u9032\u3001\u30d5\u30a3\u30d6\u30ea\u30f3\u306a\u3069\u306e\u8840\u6f3f\u6210\u5206\u306e\u8840\u7ba1\u58c1\u3078\u306e\u6d78\u6f64\u3001\u8840\u7ba1\u5468\u56f2\u306e\u708e\u75c7\u7d30\u80de\u306e\u6d3b\u6027\u5316\u3082\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u75c5\u7406\u5b66\u7684\u5909\u5316\u306f\u3001CAA\u306b\u7279\u5fb4\u7684\u306a\u8133\u51fa\u8840\u306e\u767a\u751f\u306b\u3064\u306a\u304c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3053\u3067\u91cd\u8981\u306a\u306e\u306f\u3001A\u03b2\u6c88\u7740\u81ea\u4f53\u3068\u3001\u5b9f\u969b\u306b\u8133\u51fa\u8840\u3092\u5f15\u304d\u8d77\u3053\u3059\u8840\u7ba1\u58c1\u7834\u7dbb\u306f\u3001\u540c\u3058\u6bb5\u968e\u306e\u73fe\u8c61\u3067\u306f\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001A\u03b2\u3092\u691c\u51fa\u3059\u308b\u3060\u3051\u3067\u5c06\u6765\u306e\u8133\u51fa\u8840\u306e\u767a\u75c7\u3092\u6b63\u78ba\u306b\u4e88\u6e2c\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"516\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-135-edited.png\" alt=\"\" class=\"wp-image-9386\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-135-edited.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-135-edited-400x258.png 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f31\uff1a\u8133\u30a2\u30df\u30ed\u30a4\u30c9\u30a2\u30f3\u30ae\u30aa\u30d1\u30c1\u30fc\uff08CAA\uff09\u306e\u75c5\u7406\u7d44\u7e54\u5b66\u7684\u7279\u5fb4<\/strong>\u3000\u3000\u6297\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\uff08A\u03b2\uff09\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272\u306b\u3088\u308bCAA\u306e\u75c5\u7406\u6240\u898b\u3002<strong>A\uff1a\u8efd\u75c7\u30fb\u4e2d\u7b49\u75c7CAA\u3002<\/strong> \u9ec4\u8272\u77e2\u5370\u306f\u8840\u7ba1\u58c1\u3078\u306e\u9650\u5c40\u6027A\u03b2\u6c88\u7740\u3001\u767d\u8272\u77e2\u5370\u306f\u8840\u7ba1\u58c1\u5168\u5468\u306b\u53ca\u3076A\u03b2\u6c88\u7740\u3001\u9ed2\u8272\u77e2\u5370\u306f\u8133\u5b9f\u8cea\u5185\u306eA\u03b2\u967d\u6027\u8001\u4eba\u6591\u3092\u793a\u3059\u3002\u540c\u4e00\u8133\u5185\u3067\u3082CAA\u306e\u75c5\u7406\u5b66\u7684\u91cd\u75c7\u5ea6\u306f\u8840\u7ba1\u3054\u3068\u306b\u7570\u306a\u308b\u3002<strong>B\uff1a\u4e2d\uff5e\u91cd\u75c7CAA\u3002<\/strong> A\u03b2\u6c88\u7740\u3092\u4f34\u3046\u8840\u7ba1\u58c1\u306e\u540c\u5fc3\u5186\u72b6\u5206\u96e2\u304c\u8a8d\u3081\u3089\u308c\u3001vessel-within-vessel\u69d8\u69cb\u9020\u3092\u5f62\u6210\u3057\u3066\u3044\u308b\u3002<strong>C\uff1aCAA\u95a2\u9023\u708e\u75c7\uff08CAA-ri\uff09\u3002<\/strong> A\u03b2\u967d\u6027\u8840\u7ba1\u306e\u5468\u56f2\u306b\u5358\u6838\u7403\u6027\u708e\u75c7\u7d30\u80de\u306e\u6d78\u6f64\u304c\u8a8d\u3081\u3089\u308c\u308b\u3002\u6297A\u03b2\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272\u3001\u30d8\u30de\u30c8\u30ad\u30b7\u30ea\u30f3\u5bfe\u6bd4\u67d3\u8272\u3002\u30b9\u30b1\u30fc\u30eb\u30d0\u30fc\uff1a50 \u00b5m\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4\uff0eCAA\u306f\u6570\u5341\u5e74\u304b\u3051\u3066\u9032\u884c\u3059\u308b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306e\u7279\u5fb4\u306e\u4e00\u3064\u306f\u3001\u75c5\u7406\u5b66\u7684\u5909\u5316\u304c\u59cb\u307e\u3063\u3066\u304b\u3089\u75c7\u72b6\u304c\u73fe\u308c\u308b\u307e\u3067\u306b\u3001\u975e\u5e38\u306b\u9577\u3044\u6642\u9593\u304c\u304b\u304b\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NEJM\u7dcf\u8aac\u3067\u306f\u3001\u907a\u4f1d\u6027CAA\u306e\u4e00\u3064\u3067\u3042\u308bDutch-type APP\u5909\u7570\u4fdd\u6709\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u304b\u3089\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u7d4c\u904e\u304c\u7d39\u4ecb\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u521d\u56de\u8133\u51fa\u8840\u307e\u3067\u306e\u671f\u9593<\/th><th>\u4e3b\u306a\u5909\u5316<\/th><\/tr><tr><td>\u7d0430\u301c40\u5e74\u524d<\/td><td>\u8133\u810a\u9ac4\u6db2A\u03b2\u306e\u4f4e\u4e0b\u306a\u3069\u3001\u6c88\u7740\u3092\u53cd\u6620\u3059\u308b\u5909\u5316<\/td><\/tr><tr><td>\u7d0420\u301c30\u5e74\u524d<\/td><td>\u8133\u8840\u7ba1\u53cd\u5fdc\u6027\u306e\u4f4e\u4e0b<\/td><\/tr><tr><td>\u7d0410\u301c15\u5e74\u524d<\/td><td>\u62e1\u6563\u30c6\u30f3\u30bd\u30ebMRI\u306a\u3069\u3067\u691c\u51fa\u3055\u308c\u308b\u8133\u7d44\u7e54\u969c\u5bb3<\/td><\/tr><tr><td>\u75c7\u5019\u6027\u6bb5\u968e<\/td><td>\u8133\u8449\u51fa\u8840\u3001\u5fae\u5c0f\u51fa\u8840\u3001\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u306a\u3069<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u306f\u4e3b\u306b\u907a\u4f1d\u6027CAA\u306e\u7814\u7a76\u304b\u3089\u63a8\u5b9a\u3055\u308c\u305f\u6642\u9593\u8ef8\u3067\u3042\u308a\u3001\u4e00\u822c\u7684\u306a\u5b64\u767a\u6027CAA\u306e\u3059\u3079\u3066\u306e\u60a3\u8005\u3055\u3093\u306b\u3001\u305d\u306e\u307e\u307e\u5f53\u3066\u306f\u307e\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u7814\u7a76\u304c\u793a\u3059\u6700\u3082\u91cd\u8981\u306a\u70b9\u306f\u3001\u8133\u51fa\u8840\u304c\u751f\u3058\u308b\u304b\u306a\u308a\u4ee5\u524d\u304b\u3089\u3001\u8840\u7ba1\u6a5f\u80fd\u969c\u5bb3\u3084\u5fae\u7d30\u306a\u8133\u7d44\u7e54\u969c\u5bb3\u304c\u9032\u3093\u3067\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5c06\u6765\u3001\u65e9\u671f\u8a3a\u65ad\u6cd5\u3068\u75c5\u614b\u9032\u884c\u3092\u6291\u3048\u308b\u6cbb\u7642\u304c\u958b\u767a\u3055\u308c\u308c\u3070\u3001\u8133\u51fa\u8840\u304c\u8d77\u304d\u308b\u524d\u306b\u4ecb\u5165\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5\uff0eCAA\u306e\u4e3b\u306a\u75c7\u72b6\uff1a\u8133\u51fa\u8840\u3060\u3051\u3067\u306f\u306a\u3044<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306b\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u7279\u5fb4\u7684\u306a\u81e8\u5e8a\u75c7\u72b6\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u8133\u8449\u51fa\u8840\uff08Lobar Intracerebral Hemorrhage\uff09<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306b\u3088\u308b\u8133\u51fa\u8840\u306f\u3001\u5927\u8133\u76ae\u8cea\u3084\u76ae\u8cea\u76f4\u4e0b\u306e\u767d\u8cea\u306a\u3069\u3001\u8133\u306e\u8868\u9762\u306b\u8fd1\u3044\u90e8\u5206\u306b\u767a\u751f\u3059\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3092\u8133\u8449\u51fa\u8840\uff08lobar intracerebral hemorrhage\uff09\u3068\u547c\u3073\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u8840\u5727\u6027\u7d30\u52d5\u8108\u786c\u5316\u306b\u95a2\u9023\u3057\u305f\u8133\u51fa\u8840\u304c\u88ab\u6bbb\u3001\u8996\u5e8a\u3001\u8133\u5e79\u306a\u3069\u306e\u6df1\u90e8\u306b\u751f\u3058\u3084\u3059\u3044\u3053\u3068\u3068\u5bfe\u7167\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u51fa\u8840\u306e\u75c7\u72b6\u306f\u51fa\u8840\u90e8\u4f4d\u3084\u5927\u304d\u3055\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u3001\u7a81\u7136\u306e\u7247\u9ebb\u75fa\u3001\u8a00\u8a9e\u969c\u5bb3\u3001\u982d\u75db\u3001\u610f\u8b58\u969c\u5bb3\u306a\u3069\u304c\u751f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306bCAA\u3067\u306f\u3001\u4e00\u5ea6\u8133\u51fa\u8840\u3092\u8d77\u3053\u3057\u305f\u5f8c\u306e\u518d\u51fa\u8840\u304c\u91cd\u8981\u306a\u554f\u984c\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306f\u3001\u660e\u3089\u304b\u306a\u8133\u51fa\u8840\u3092\u7d4c\u9a13\u3057\u3066\u3044\u306a\u3044\u60a3\u8005\u3055\u3093\u3067\u3082\u3001\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306b\u95a2\u4fc2\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4ee3\u8868\u7684\u306a\u969c\u5bb3\u306f\u3001\u60c5\u5831\u51e6\u7406\u901f\u5ea6\u306e\u4f4e\u4e0b\u3084\u3001\u8a08\u753b\u30fb\u5224\u65ad\u30fb\u6ce8\u610f\u306e\u5207\u308a\u66ff\u3048\u306a\u3069\u306e\u9042\u884c\u6a5f\u80fd\u969c\u5bb3\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u767d\u8cea\u75c5\u5909\u3084\u5fae\u5c0f\u6897\u585e\u306a\u3069\u3001\u8907\u6570\u306e\u8133\u5c0f\u8840\u7ba1\u75c5\u5909\u304c\u95a2\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NEJM\u7dcf\u8aac\u3067\u5f15\u7528\u3055\u308c\u305f\u5256\u691c\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u3067\u306f\u3001\u4e2d\u7b49\u5ea6\u301c\u91cd\u5ea6\u306eCAA\u304c\u5b58\u5728\u3059\u308b\u5834\u5408\u3001\u89e3\u6790\u30e2\u30c7\u30eb\u4e0a\u3001\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306e\u7d0416%\u306b\u5bc4\u4e0e\u3059\u308b\u3068\u63a8\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u306e16%\u306f\u500b\u3005\u306e\u60a3\u8005\u3055\u3093\u306e\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306e\u3046\u3061\u3001\u5e38\u306b16%\u304cCAA\u306b\u3088\u3063\u3066\u751f\u3058\u308b\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001CAA\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u304c\u4f75\u5b58\u3059\u308b\u3068\u3001\u81e8\u5e8a\u75c7\u72b6\u306e\u307f\u3067\u4e21\u8005\u306e\u5f71\u97ff\u3092\u533a\u5225\u3059\u308b\u3053\u3068\u306f\u56f0\u96e3\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u4e00\u904e\u6027\u5c40\u6240\u795e\u7d4c\u75c7\u72b6\uff08TFNE\uff1aAmyloid Spells\uff09<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u3067\u306f\u3001\u77ed\u6642\u9593\u306e\u795e\u7d4c\u75c7\u72b6\u304c\u7e70\u308a\u8fd4\u3057\u73fe\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u822c\u306b30\u5206\u672a\u6e80\u3067\u3001\u7247\u5074\u306e\u3057\u3073\u308c\u3001\u8131\u529b\u3001\u611f\u899a\u7570\u5e38\u3001\u308d\u308c\u3064\u304c\u56de\u3089\u306a\u3044\u3001\u8a00\u8449\u304c\u51fa\u306b\u304f\u3044\u3001\u3068\u3044\u3063\u305f\u75c7\u72b6\u304c\u307f\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u5fb4\u7684\u306a\u306e\u306f\u3001\u75c7\u72b6\u304c\u6570\u5206\u304b\u3051\u3066\u96a3\u63a5\u3059\u308b\u8eab\u4f53\u90e8\u4f4d\u3078\u5e83\u304c\u308a\u3001\u6570\u65e5\u304b\u3089\u6570\u9031\u9593\u306e\u9593\u306b\u4f3c\u305f\u767a\u4f5c\u304c\u7e70\u308a\u8fd4\u3055\u308c\u308b\u5834\u5408\u304c\u3042\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u4e00\u904e\u6027\u8133\u865a\u8840\u767a\u4f5c\uff08TIA\uff09\u306b\u4f3c\u3066\u3044\u307e\u3059\u304c\u3001\u80cc\u666f\u306e\u75c5\u614b\u304c\u7570\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u95a2\u9023TFNE\u3067\u306f\u3001\u76ae\u8cea\u5186\u84cb\u90e8\u304f\u3082\u819c\u4e0b\u51fa\u8840\u3084\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u304c\u78ba\u8a8d\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u76ae\u8cea\u62e1\u5ef6\u6027\u8131\u5206\u6975\uff08cortical spreading depolarization\uff09\u306e\u95a2\u4e0e\u304c\u63a8\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u91cd\u8981\u306a\u306e\u306f\u3001CAA\u95a2\u9023TFNE\u3092\u5358\u7d14\u306bTIA\u3068\u5224\u65ad\u3057\u3001\u753b\u50cf\u8a55\u4fa1\u304c\u4e0d\u5341\u5206\u306a\u307e\u307e\u6297\u8840\u6813\u7642\u6cd5\u3092\u958b\u59cb\u3057\u306a\u3044\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001TFNE\u3068\u601d\u308f\u308c\u308b\u75c7\u72b6\u3067\u3042\u3063\u3066\u3082\u3001\u6025\u6027\u8133\u6897\u585e\u3084TIA\u3092\u76f4\u3061\u306b\u9664\u5916\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u65b0\u305f\u306a\u7247\u9ebb\u75fa\u3084\u8a00\u8a9e\u969c\u5bb3\u306a\u3069\u304c\u51fa\u73fe\u3057\u305f\u5834\u5408\u306f\u3001\u75c7\u72b6\u304c\u6539\u5584\u3057\u3066\u3082\u6551\u6025\u3067\u306e\u8133\u5352\u4e2d\u8a55\u4fa1\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6\uff0eCAA\u306eMRI\u8a3a\u65ad\uff1aBoston criteria version 2.0<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306e\u8a3a\u65ad\u306b\u304a\u3044\u3066\u3001\u6700\u3082\u91cd\u8981\u306a\u306e\u306fMRI\u306b\u3088\u308b\u8133\u51fa\u8840\u6027\u75c5\u5909\u306e\u5206\u5e03\u8a55\u4fa1\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306bT2*\u5f37\u8abf\u753b\u50cf\u3084\u78c1\u5316\u7387\u5f37\u8abf\u753b\u50cf\uff08SWI\uff09\u306f\u3001\u901a\u5e38\u306eMRI\u753b\u50cf\u3067\u306f\u5206\u304b\u308a\u306b\u304f\u3044\u5fae\u5c0f\u306a\u51fa\u8840\u3084\u9244\u6c88\u7740\u3092\u691c\u51fa\u3059\u308b\u305f\u3081\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u4ee3\u8868\u7684\u306a\u753b\u50cf\u6240\u898b<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u753b\u50cf\u6240\u898b<\/th><th>\u7279\u5fb4<\/th><\/tr><tr><td>\u8133\u8449\u51fa\u8840<\/td><td>\u76ae\u8cea\u30fb\u76ae\u8cea\u4e0b\u306e\u51fa\u8840<\/td><\/tr><tr><td>\u8133\u8449\u5fae\u5c0f\u51fa\u8840<\/td><td>T2*\/SWI\u3067\u4f4e\u4fe1\u53f7\u3068\u306a\u308b\u5c0f\u75c5\u5909<\/td><\/tr><tr><td>\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\uff08cSS\uff09<\/td><td>\u8133\u6e9d\u306b\u6cbf\u3063\u305f\u8840\u6db2\u5206\u89e3\u7523\u7269\u306e\u6c88\u7740<\/td><\/tr><tr><td>\u76ae\u8cea\u5186\u84cb\u90e8\u304f\u3082\u819c\u4e0b\u51fa\u8840\uff08cSAH\uff09<\/td><td>\u8133\u8868\u306e\u9650\u5c40\u3057\u305f\u304f\u3082\u819c\u4e0b\u51fa\u8840<\/td><\/tr><tr><td>\u534a\u5375\u5186\u4e2d\u5fc3\u306e\u8840\u7ba1\u5468\u56f2\u8154\u62e1\u5927<\/td><td>\u975e\u51fa\u8840\u6027\u306eMRI\u30de\u30fc\u30ab\u30fc<\/td><\/tr><tr><td>\u591a\u767a\u6591\u70b9\u72b6\u767d\u8cea\u9ad8\u4fe1\u53f7<\/td><td>\u7279\u5fb4\u7684\u306a\u5206\u5e03\u3092\u793a\u3059\u767d\u8cea\u75c5\u5909<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Boston criteria version 2.0\uff1aProbable CAA<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c5\u7406\u7d44\u7e54\u3092\u5f97\u305a\u306bCAA\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u5224\u5b9a\u3059\u308b\u305f\u3081\u306e\u8a3a\u65ad\u57fa\u6e96\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u57fa\u672c\u6761\u4ef6\u306f\u300150\u6b73\u4ee5\u4e0a\u3067\u3001\u81ea\u7136\u767a\u75c7\u306e\u8133\u5185\u51fa\u8840\u3001\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3001\u307e\u305f\u306f\u4e00\u904e\u6027\u5c40\u6240\u795e\u7d4c\u75c7\u72b6\u306a\u3069\u306e\u81e8\u5e8a\u50cf\u3092\u6709\u3059\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">MRI\u3067\u306f\u3001\u4ee5\u4e0b\u306e\u3044\u305a\u308c\u304b\u3092\u6e80\u305f\u3059\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6761\u4ef6A\uff1a\u51fa\u8840\u6027\u75c5\u5909\u304c2\u3064\u4ee5\u4e0a<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u8449\u51fa\u8840\u3001\u8133\u8449\u5fae\u5c0f\u51fa\u8840\u3001\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u3001\u76ae\u8cea\u5186\u84cb\u90e8\u304f\u3082\u819c\u4e0b\u51fa\u8840\u306a\u3069\u306e\u3001CAA\u306b\u7279\u5fb4\u7684\u306a\u51fa\u8840\u6027\u75c5\u5909\u304c2\u3064\u4ee5\u4e0a\u5b58\u5728\u3059\u308b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6761\u4ef6B\uff1a\u51fa\u8840\u6027\u75c5\u59091\u3064\uff0b\u975e\u51fa\u8840\u6027\u30de\u30fc\u30ab\u30fc1\u3064<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u8449\u306e\u51fa\u8840\u6027\u75c5\u5909\u304c1\u3064\u3042\u308a\u3001\u3055\u3089\u306b\u6b21\u306e\u3044\u305a\u308c\u304b\u3092\u8a8d\u3081\u308b\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u534a\u5375\u5186\u4e2d\u5fc3\u306b\u304a\u3051\u308b\u9ad8\u5ea6\u306e\u8840\u7ba1\u5468\u56f2\u8154\u62e1\u5927<\/li>\n\n\n\n<li>\u591a\u767a\u6591\u70b9\u72b6\u306e\u767d\u8cea\u9ad8\u4fe1\u53f7\u75c5\u5909<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u52a0\u3048\u3066\u3001\u57fa\u5e95\u6838\u30fb\u8996\u5e8a\u30fb\u8133\u5e79\u306a\u3069\u306b\u3001CAA\u4ee5\u5916\u306e\u75c5\u614b\u3092\u793a\u5506\u3059\u308b\u81ea\u7136\u767a\u75c7\u306e\u6df1\u90e8\u51fa\u8840\u6027\u75c5\u5909\u3092\u8a8d\u3081\u305a\u3001\u5916\u50b7\u3001\u8840\u7ba1\u5947\u5f62\u3001\u51fa\u8840\u6027\u816b\u760d\u3001\u8840\u7ba1\u708e\u306a\u3069\u306e\u4ed6\u306e\u51fa\u8840\u539f\u56e0\u304c\u306a\u3044\u3053\u3068\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u306a\u304a\u3001\u534a\u5375\u5186\u4e2d\u5fc3\u306e\u9ad8\u5ea6\u8840\u7ba1\u5468\u56f2\u8154\u62e1\u5927\u306f\u7247\u5074\u5927\u8133\u534a\u7403\u306720\u500b\u3092\u8d85\u3048\u308b\u6240\u898b\u3001\u591a\u767a\u6591\u70b9\u72b6\u767d\u8cea\u9ad8\u4fe1\u53f7\u306f\u4e21\u5074\u76ae\u8cea\u4e0b\u767d\u8cea\u306b\u5408\u8a0810\u500b\u3092\u8d85\u3048\u308b\u5c0f\u5186\u5f62\u30fb\u5375\u5186\u5f62\u75c5\u5909\u3092\u6307\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Boston criteria version 2.0\u306e\u8a3a\u65ad\u7cbe\u5ea6<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">NEJM\u7dcf\u8aac\u3067\u5f15\u7528\u3055\u308c\u305fMRI\u30fb\u75c5\u7406\u5bfe\u5fdc\u7814\u7a76\u3067\u306f\u3001Probable CAA\u306e\u8a3a\u65ad\u7cbe\u5ea6\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u611f\u5ea6<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">74.5%<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c5\u7406\u5b66\u7684CAA\u3092\u753b\u50cf\u57fa\u6e96\u3067\u691c\u51fa\u3059\u308b\u5272\u5408<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u7570\u5ea6<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">95.0%<\/h1>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c5\u7406\u5b66\u7684CAA\u304c\u306a\u3044\u75c7\u4f8b\u3092\u6b63\u3057\u304f\u9664\u5916\u3059\u308b\u5272\u5408<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a3a\u65ad\u611f\u5ea6\u306f\u81e8\u5e8a\u50cf\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u3001\u8133\u8449\u51fa\u8840\u3067\u767a\u75c7\u3057\u305f\u60a3\u8005\u3067\u306f90.2%\u3067\u3042\u308b\u4e00\u65b9\u3001\u8133\u51fa\u8840\u3092\u4f34\u308f\u306a\u3044\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306a\u3069\u306e\u60a3\u8005\u3067\u306f55.1%\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u91cd\u8981\u306a\u9650\u754c\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Boston criteria version 2.0\u306fCAA\u306e\u8a3a\u65ad\u306b\u9ad8\u3044\u7279\u7570\u5ea6\u3092\u6709\u3057\u307e\u3059\u304c\u3001\u51fa\u8840\u6027\u75c5\u5909\u304c\u5c11\u306a\u3044\u65e9\u671fCAA\u3084\u975e\u51fa\u8840\u6027CAA\u3092\u5341\u5206\u306b\u691c\u51fa\u3067\u304d\u306a\u3044\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u30a2\u30df\u30ed\u30a4\u30c9PET\u306f\u8133\u5185\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u6c88\u7740\u3092\u691c\u51fa\u3067\u304d\u307e\u3059\u304c\u3001CAA\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u8b58\u5225\u306b\u306f\u9650\u754c\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u810a\u9ac4\u6db2\u3067\u306f\u3001CAA\u3067A\u03b240\u3068A\u03b242\u306e\u53cc\u65b9\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001A\u03b240\u306e\u4f4e\u4e0b\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3068\u306e\u9451\u5225\u306b\u5f79\u7acb\u3064\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306f\u5358\u72ec\u3067\u78ba\u5b9a\u8a3a\u65ad\u3059\u308b\u305f\u3081\u306e\u691c\u67fb\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"572\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-129.png\" alt=\"\u8133\u8449\u5fae\u5c0f\u51fa\u8840\u3001\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u3001\u767d\u8cea\u75c5\u5909\u3092\u7528\u3044\u305fBoston criteria version 2.0\u306eCAA\u8a3a\u65ad\u30d5\u30ed\u30fc\u30c1\u30e3\u30fc\u30c8\" class=\"wp-image-9367\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-129.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-129-400x286.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-129-768x549.png 768w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u56f3\uff1aBoston criteria version 2.0\u306b\u3088\u308bProbable CAA\u306e\u753b\u50cf\u8a3a\u65ad\u300250\u6b73\u4ee5\u4e0a\u3067\u7279\u5fb4\u7684\u306a\u81e8\u5e8a\u75c7\u72b6\u3092\u6709\u3059\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u8907\u6570\u306e\u8133\u8449\u51fa\u8840\u6027\u75c5\u5909\u3001\u307e\u305f\u306f\u8133\u8449\u51fa\u8840\u6027\u75c5\u59091\u3064\u3068\u7279\u5b9a\u306e\u975e\u51fa\u8840\u6027\u767d\u8cea\u30de\u30fc\u30ab\u30fc\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u308a\u8a3a\u65ad\u3002\u6df1\u90e8\u51fa\u8840\u6027\u75c5\u5909\u3084\u4ed6\u306e\u51fa\u8840\u539f\u56e0\u304c\u5b58\u5728\u3057\u306a\u3044\u3053\u3068\u3092\u78ba\u8a8d\u3059\u308b\u3002MRI\u30fb\u75c5\u7406\u5bfe\u5fdc\u7814\u7a76\u306b\u304a\u3051\u308b\u8a3a\u65ad\u611f\u5ea674.5%\u3001\u7279\u7570\u5ea695.0%\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">7\uff0eCAA\u306e\u6700\u3082\u91cd\u8981\u306a\u554f\u984c\uff1a\u8133\u51fa\u8840\u306e\u518d\u767a\u30ea\u30b9\u30af<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306b\u95a2\u9023\u3057\u305f\u8133\u51fa\u8840\u306f\u3001\u4ed6\u306e\u539f\u56e0\u306b\u3088\u308b\u8133\u51fa\u8840\u3068\u6bd4\u8f03\u3057\u3066\u518d\u767a\u3057\u3084\u3059\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NEJM\u7dcf\u8aac\u3067\u306f\u3001\u8133\u5185\u51fa\u8840\u60a3\u80051,306\u4eba\u306e\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u3057\u305f\u30e1\u30bf\u89e3\u6790\u304c\u7d39\u4ecb\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u5185\u51fa\u8840\u306e\u5e74\u9593\u518d\u767a\u7387<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NEJM\u7dcf\u8aac\u306b\u5f15\u7528\u3055\u308c\u305f\u30e1\u30bf\u89e3\u6790\u3002\u6570\u5024\u306f\u5e74\u9593\u518d\u767a\u7387\u3067\u3042\u308a\u3001\u521d\u56de\u8133\u51fa\u8840\u306e\u767a\u75c7\u7387\u3067\u306f\u306a\u3044\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">0%2.5%5%7.5%10%CAA\u95a2\u9023\u8133\u51fa\u8840CAA\u975e\u95a2\u9023\u8133\u51fa\u8840<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u95a2\u9023\u8133\u51fa\u8840\uff1a7.4%\/\u5e74\uff0895% CI 3.2\u201312.6\uff09\u3002CAA\u975e\u95a2\u9023\u8133\u51fa\u8840\uff1a1.1%\/\u5e74\uff0895% CI 0.5\u20131.7\uff09\u3002Charidimou\u3089\u306e\u30e1\u30bf\u89e3\u6790\u3092NEJM\u7dcf\u8aac\u304b\u3089\u5f15\u7528\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u95a2\u9023\u8133\u51fa\u8840\u306e\u5e74\u9593\u518d\u767a\u7387\u306f7.4%\u3001CAA\u975e\u95a2\u9023\u8133\u51fa\u8840\u3067\u306f1.1%\u3068\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u7d50\u679c\u306f\u3001CAA\u304c\u518d\u767a\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u8133\u51fa\u8840\u306e\u539f\u56e0\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u306e\u6570\u5024\u306f\u65e2\u306b\u8133\u51fa\u8840\u3092\u7d4c\u9a13\u3057\u305f\u60a3\u8005\u96c6\u56e3\u304b\u3089\u5f97\u3089\u308c\u305f\u3082\u306e\u3067\u3042\u308a\u3001MRI\u3067\u5076\u7136CAA\u3092\u7591\u3046\u6240\u898b\u304c\u898b\u3064\u304b\u3063\u305f\u7121\u75c7\u5019\u6027\u60a3\u8005\u306e\u5e74\u9593\u51fa\u8840\u30ea\u30b9\u30af\u3092\u793a\u3059\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u518d\u51fa\u8840\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u56e0\u5b50<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">NEJM\u7dcf\u8aac\u3067\u306f\u3001\u4ee5\u4e0b\u304c\u518d\u51fa\u8840\u30ea\u30b9\u30af\u306b\u95a2\u9023\u3059\u308b\u56e0\u5b50\u3068\u3057\u3066\u6319\u3052\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\uff08cSS\uff09\u3001\u7279\u306b\u591a\u767a\u6027\u30fb\u5e83\u7bc4\u306a\u6240\u898b<\/li>\n\n\n\n<li>\u904e\u53bb\u306b\u8907\u6570\u56de\u306e\u8133\u8449\u51fa\u8840\u3092\u8d77\u3053\u3057\u3066\u3044\u308b\u3053\u3068<\/li>\n\n\n\n<li>\u8840\u5727\u304c\u9ad8\u3044\u3053\u3068<\/li>\n\n\n\n<li>APOE \u03b52\u307e\u305f\u306f\u03b54\u30a2\u30ec\u30eb\u3092\u6709\u3059\u308b\u3053\u3068<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u8133\u8449\u5fae\u5c0f\u51fa\u8840\u306f\u8907\u6570\u8a8d\u3081\u308b\u3082\u306e\u306e\u3001\u660e\u3089\u304b\u306a\u8133\u8449\u51fa\u8840\u3084\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u3092\u8a8d\u3081\u306a\u3044\u75c7\u4f8b\u3067\u306f\u3001\u76f8\u5bfe\u7684\u306b\u4f4e\u3044\u51fa\u8840\u30ea\u30b9\u30af\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">80\u4eba\u306eProbable CAA\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5358\u65bd\u8a2d\u7814\u7a76\u3067\u306f\u3001\u3053\u306e\u3088\u3046\u306a\u60a3\u8005\u306e\u521d\u56de\u8840\u816b\u5f62\u6210\u30ea\u30b9\u30af\u306f5\u5e74\u9593\u3067\u7d046%\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u3088\u3046\u306b\u3001CAA\u3068\u8a3a\u65ad\u3055\u308c\u305f\u60a3\u8005\u3055\u3093\u3067\u3082\u3001MRI\u6240\u898b\u3084\u51fa\u8840\u6b74\u306b\u3088\u3063\u3066\u30ea\u30b9\u30af\u306f\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"533\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-136-edited.png\" alt=\"CAA\u95a2\u9023\u8133\u51fa\u8840\u3068\u975eCAA\u95a2\u9023\u8133\u51fa\u8840\u306e\u5e74\u9593\u518d\u767a\u7387\u304a\u3088\u307395%\u4fe1\u983c\u533a\u9593\u306e\u6bd4\u8f03\u30b0\u30e9\u30d5\u3002\" class=\"wp-image-9389\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-136-edited.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-136-edited-400x267.png 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u56f3\uff1aCAA\u95a2\u9023\u8133\u51fa\u8840\u3068\u975eCAA\u95a2\u9023\u8133\u51fa\u8840\u306b\u304a\u3051\u308b\u5e74\u9593\u518d\u767a\u7387\u306e\u6bd4\u8f03\u30021,306\u4f8b\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30e1\u30bf\u89e3\u6790\u306b\u304a\u3044\u3066\u3001\u5e74\u9593\u518d\u767a\u7387\u306fCAA\u95a2\u9023\u8133\u51fa\u8840\u30677.4%\uff0895% CI 3.2\u201312.6\uff09\u3001\u975eCAA\u95a2\u9023\u8133\u51fa\u8840\u30671.1%\uff0895% CI 0.5\u20131.7\uff09\u3068\u5831\u544a\u3055\u308c\u305f\u3002\u3053\u308c\u3089\u306f\u96c6\u56e3\u30ec\u30d9\u30eb\u306e\u63a8\u5b9a\u5024\u3067\u3042\u308a\u3001\u500b\u3005\u306e\u60a3\u8005\u306e\u518d\u767a\u78ba\u7387\u3092\u76f4\u63a5\u793a\u3059\u3082\u306e\u3067\u306f\u306a\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">8\uff0eCAA\u60a3\u8005\u306b\u6297\u51dd\u56fa\u85ac\u30fb\u6297\u8840\u5c0f\u677f\u85ac\u3092\u4f7f\u7528\u3057\u3066\u3088\u3044\u306e\u304b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306e\u8a3a\u7642\u3067\u6700\u3082\u96e3\u3057\u3044\u554f\u984c\u306e\u4e00\u3064\u304c\u3001\u5fc3\u623f\u7d30\u52d5\u306a\u3069\u3092\u5408\u4f75\u3057\u305f\u60a3\u8005\u3055\u3093\u306b\u5bfe\u3059\u308b\u6297\u8840\u6813\u7642\u6cd5\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5fc3\u623f\u7d30\u52d5\u3067\u306f\u3001\u5fc3\u81d3\u5185\u306b\u3067\u304d\u305f\u8840\u6813\u304c\u8133\u8840\u7ba1\u3092\u9589\u585e\u3059\u308b\u3053\u3068\u3067\u3001\u91cd\u3044\u8133\u6897\u585e\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001CAA\u60a3\u8005\u3055\u3093\u3067\u306f\u3001\u6297\u51dd\u56fa\u7642\u6cd5\u306b\u3088\u3063\u3066\u982d\u84cb\u5185\u51fa\u8840\u306e\u5371\u967a\u6027\u304c\u5897\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3064\u307e\u308a\u3001\u8133\u6897\u585e\u3092\u4e88\u9632\u3059\u308b\u5229\u76ca\u3068\u3001\u8133\u51fa\u8840\u3092\u5f15\u304d\u8d77\u3053\u3059\u5371\u967a\u6027\u3092\u6bd4\u8f03\u3057\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6297\u51dd\u56fa\u7642\u6cd5\u306e\u5224\u65ad\u306f\u4e00\u5f8b\u306b\u306f\u3067\u304d\u306a\u3044<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306eNEJM\u7dcf\u8aac\u3067\u306f\u3001CAA\u3092\u6709\u3059\u308b\u5fc3\u623f\u7d30\u52d5\u60a3\u8005\u306b\u5bfe\u3059\u308b\u6297\u51dd\u56fa\u7642\u6cd5\u306e\u6700\u9069\u306a\u4f7f\u7528\u65b9\u91dd\u306b\u3064\u3044\u3066\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u3092\u542b\u3080\u65e2\u5b58\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u3082\u660e\u78ba\u306a\u7d50\u8ad6\u306b\u81f3\u3063\u3066\u3044\u306a\u3044\u3068\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5224\u65ad\u306b\u304a\u3044\u3066\u306f\u3001\u5fc3\u539f\u6027\u8133\u585e\u6813\u75c7\u306e\u30ea\u30b9\u30af\u3001\u904e\u53bb\u306e\u8133\u51fa\u8840\u6b74\u3001MRI\u3067\u306e\u5fae\u5c0f\u51fa\u8840\u3084\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u306e\u5206\u5e03\u306a\u3069\u3092\u7dcf\u5408\u7684\u306b\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f8b\u3048\u3070\u3001\u8133\u51fa\u8840\u6b74\u3084\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u304c\u306a\u304f\u3001\u5fae\u5c0f\u51fa\u8840\u306e\u307f\u8a8d\u3081\u308b\u60a3\u8005\u3055\u3093\u3067\u306f\u3001\u5fc3\u539f\u6027\u8133\u585e\u6813\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5834\u5408\u3001\u76f4\u63a5\u4f5c\u7528\u578b\u7d4c\u53e3\u6297\u51dd\u56fa\u85ac\uff08DOAC\uff09\u3092\u691c\u8a0e\u3059\u308b\u4f59\u5730\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u904e\u53bb\u306b\u8907\u6570\u56de\u306e\u8133\u51fa\u8840\u3092\u8d77\u3053\u3057\u3001\u518d\u51fa\u8840\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u60a3\u8005\u3055\u3093\u3067\u306f\u3001\u6297\u51dd\u56fa\u7642\u6cd5\u4ee5\u5916\u306e\u6cbb\u7642\u9078\u629e\u80a2\u3092\u691c\u8a0e\u3059\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u539f\u8457\u7dcf\u8aac\u306e\u8457\u8005\u304c\u793a\u3057\u305f\u81e8\u5e8a\u7684\u8003\u3048\u65b9\u3067\u3042\u308a\u3001\u3059\u3079\u3066\u306e\u60a3\u8005\u306b\u4e00\u5f8b\u306b\u9069\u7528\u3059\u308b\u6cbb\u7642\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\u3001DOAC\u3001\u5de6\u5fc3\u8033\u9589\u9396\u8853\u306e\u4f4d\u7f6e\u3065\u3051<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th>\u6cbb\u7642\u9078\u629e\u80a2<\/th><th>CAA\u60a3\u8005\u3067\u306e\u8003\u3048\u65b9<\/th><\/tr><tr><td>\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3<\/td><td>DOAC\u304c\u9069\u5fdc\u3068\u306a\u308b\u5834\u5408\u306b\u306f\u3001\u4e00\u822c\u306b\u982d\u84cb\u5185\u51fa\u8840\u30ea\u30b9\u30af\u306e\u89b3\u70b9\u304b\u3089\u56de\u907f\u304c\u691c\u8a0e\u3055\u308c\u308b<\/td><\/tr><tr><td>DOAC<\/td><td>\u5fc3\u539f\u6027\u585e\u6813\u75c7\u306e\u4e88\u9632\u5229\u76ca\u3068CAA\u95a2\u9023\u51fa\u8840\u30ea\u30b9\u30af\u3092\u500b\u5225\u306b\u8a55\u4fa1<\/td><\/tr><tr><td>\u5de6\u5fc3\u8033\u9589\u9396\u8853<\/td><td>\u9577\u671f\u6297\u51dd\u56fa\u7642\u6cd5\u304c\u96e3\u3057\u3044\u975e\u5f01\u819c\u75c7\u6027\u5fc3\u623f\u7d30\u52d5\u60a3\u8005\u3067\u691c\u8a0e\u3055\u308c\u308b\u9078\u629e\u80a2<\/td><\/tr><tr><td>\u6297\u8840\u5c0f\u677f\u85ac\u5358\u5264<\/td><td>\u72ec\u7acb\u3057\u305f\u9069\u5fdc\u304c\u3042\u308b\u5834\u5408\u306b\u691c\u8a0e\u3002\u5fc3\u623f\u7d30\u52d5\u306b\u5bfe\u3059\u308b\u6297\u51dd\u56fa\u7642\u6cd5\u3068\u540c\u7b49\u306e\u585e\u6813\u75c7\u4e88\u9632\u52b9\u679c\u306f\u306a\u3044<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u306a\u304a\u3001DOAC\u304c\u9069\u5207\u3067\u306a\u3044\u6a5f\u68b0\u5f01\u306a\u3069\u306e\u75c5\u614b\u3067\u306f\u3001\u6297\u51dd\u56fa\u7642\u6cd5\u306e\u9078\u629e\u305d\u306e\u3082\u306e\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u8133\u51fa\u8840\u5f8c\u306e\u6297\u8840\u5c0f\u677f\u85ac\u518d\u958b\u306b\u95a2\u3059\u308bRESTART\u8a66\u9a13\u306e\u7d50\u679c\u306f\u53c2\u8003\u306b\u306a\u308a\u307e\u3059\u304c\u3001\u3059\u3079\u3066\u306eCAA\u60a3\u8005\u306b\u6297\u8840\u5c0f\u677f\u85ac\u304c\u5b89\u5168\u3067\u3042\u308b\u3068\u8a3c\u660e\u3055\u308c\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u3001\u6297\u8840\u5c0f\u677f\u85ac\u5358\u5264\u3092\u5fc3\u623f\u7d30\u52d5\u306b\u5bfe\u3059\u308b\u6a19\u6e96\u7684\u306a\u6297\u51dd\u56fa\u7642\u6cd5\u306e\u4ee3\u66ff\u3068\u3057\u3066\u5b89\u6613\u306b\u4f4d\u7f6e\u3065\u3051\u308b\u3079\u304d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u8840\u5727\u7ba1\u7406\u306f\u518d\u51fa\u8840\u4e88\u9632\u306e\u57fa\u672c<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u95a2\u9023\u8133\u51fa\u8840\u5f8c\u306e\u518d\u767a\u4e88\u9632\u3067\u306f\u3001\u8840\u5727\u7ba1\u7406\u304c\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7dcf\u8aac\u3067\u306f\u3001\u4e8c\u6b21\u4e88\u9632\u306b\u304a\u3051\u308b\u8840\u5727\u7ba1\u7406\u76ee\u6a19\u3068\u3057\u3066\u3001\u539f\u5247130\/80 mmHg\u672a\u6e80\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u9ad8\u9f62\u8005\u3067\u306f\u8d77\u7acb\u6027\u4f4e\u8840\u5727\u3001\u8ee2\u5012\u3001\u814e\u6a5f\u80fd\u3001\u30d5\u30ec\u30a4\u30eb\u306a\u3069\u3092\u8003\u616e\u3057\u3001\u904e\u5ea6\u306e\u964d\u5727\u3092\u907f\u3051\u306a\u304c\u3089\u500b\u5225\u306b\u8abf\u6574\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u904e\u5ea6\u306e\u98f2\u9152\u3092\u907f\u3051\u308b\u3053\u3068\u3082\u5408\u7406\u7684\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-heading\">9\uff0eCAA\u95a2\u9023\u708e\u75c7\uff08CAA-ri\uff09\uff1a\u514d\u75ab\u6cbb\u7642\u304c\u6709\u52b9\u3068\u306a\u308a\u3046\u308b\u91cd\u8981\u306a\u75c5\u614b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306b\u306f\u3001\u8840\u7ba1\u58c1\u3078\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u6c88\u7740\u305d\u306e\u3082\u306e\u3068\u306f\u5225\u306b\u3001\u8840\u7ba1\u5468\u56f2\u306b\u5f37\u3044\u708e\u75c7\u3092\u751f\u3058\u308b\u75c5\u578b\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3092CAA\u95a2\u9023\u708e\u75c7\uff08CAA-related inflammation\uff1aCAA-ri\uff09\u3068\u547c\u3073\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA-ri\u3067\u306f\u3001\u8133\u8840\u7ba1\u306b\u6c88\u7740\u3057\u305fA\u03b2\u306b\u5bfe\u3059\u308b\u514d\u75ab\u5fdc\u7b54\u304c\u95a2\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">CAA-ri\u306e\u75c5\u614b\u3068\u75c7\u72b6<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">CAA-ri\u3067\u306f\u3001\u8840\u7ba1\u5468\u56f2\u306b\u5358\u6838\u7403\u306a\u3069\u306e\u708e\u75c7\u7d30\u80de\u6d78\u6f64\u304c\u8a8d\u3081\u3089\u308c\u3001\u8840\u7ba1\u900f\u904e\u6027\u306e\u4ea2\u9032\u3084\u8133\u767d\u8cea\u6d6e\u816b\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c7\u72b6\u306f\u6570\u9031\u9593\u304b\u3089\u6570\u304b\u6708\u306e\u7d4c\u904e\u3067\u51fa\u73fe\u3057\u3001\u982d\u75db\u3001\u3051\u3044\u308c\u3093\u767a\u4f5c\u3001\u610f\u8b58\u3084\u8a8d\u77e5\u6a5f\u80fd\u306e\u5909\u5316\u3001\u6027\u683c\u5909\u5316\u3001\u5c40\u6240\u795e\u7d4c\u8131\u843d\u75c7\u72b6\u306a\u3069\u304c\u307f\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u822c\u7684\u306aCAA\u306e\u8133\u51fa\u8840\u3068\u306f\u7570\u306a\u308a\u3001\u6bd4\u8f03\u7684\u4e9c\u6025\u6027\u306b\u9032\u884c\u3059\u308b\u8133\u708e\u30fb\u8133\u75c7\u306e\u3088\u3046\u306a\u81e8\u5e8a\u50cf\u3092\u793a\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">MRI\u3067\u306e\u7279\u5fb4<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">MRI\u3067\u306f\u3001CAA\u306b\u7279\u5fb4\u7684\u306a\u5fae\u5c0f\u51fa\u8840\u3084\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u306b\u52a0\u3048\u3066\u3001FLAIR\u753b\u50cf\u3067\u76ae\u8cea\u8fd1\u508d\u306e\u767d\u8cea\u306b\u9ad8\u4fe1\u53f7\u75c5\u5909\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c5\u5909\u306f\u5358\u767a\u307e\u305f\u306f\u591a\u767a\u6027\u3067\u3001\u3057\u3070\u3057\u3070\u975e\u5bfe\u79f0\u6027\u306b\u5206\u5e03\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u753b\u50cf\u6240\u898b\u306e\u307f\u3067CAA-ri\u3068\u78ba\u5b9a\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u4e2d\u67a2\u795e\u7d4c\u8840\u7ba1\u708e\u3001\u611f\u67d3\u6027\u8133\u708e\u3001\u816b\u760d\u6027\u75c5\u5909\u3001\u305d\u306e\u4ed6\u306e\u708e\u75c7\u6027\u30fb\u8131\u9ac4\u6027\u75be\u60a3\u3068\u306e\u9451\u5225\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u30b9\u30c6\u30ed\u30a4\u30c9\u6cbb\u7642\u306e\u6709\u52b9\u6027<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">CAA-ri\u306f\u3001\u514d\u75ab\u6291\u5236\u6cbb\u7642\u306b\u3088\u308b\u6539\u5584\u304c\u671f\u5f85\u3067\u304d\u308b\u70b9\u3067\u3001\u901a\u5e38\u306eCAA\u3068\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306eNEJM\u7dcf\u8aac\u3067\u306f\u3001\u9ad8\u7528\u91cf\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u306a\u3069\u306e\u514d\u75ab\u6291\u5236\u6cbb\u7642\u306b\u3088\u3063\u3066\u3001\u81e8\u5e8a\u75c7\u72b6\u3068MRI\u6240\u898b\u304c\u6539\u5584\u3057\u3001\u518d\u71c3\u304c\u6e1b\u5c11\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u7d39\u4ecb\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u6839\u62e0\u306f\u4e3b\u306b\u89b3\u5bdf\u7814\u7a76\u306b\u57fa\u3065\u3044\u3066\u304a\u308a\u3001\u6700\u9069\u306a\u30b9\u30c6\u30ed\u30a4\u30c9\u6295\u4e0e\u91cf\u3001\u6f38\u6e1b\u671f\u9593\u3001\u518d\u71c3\u6642\u306e\u514d\u75ab\u6291\u5236\u7642\u6cd5\u306b\u3064\u3044\u3066\u78ba\u7acb\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u3042\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30b9\u30c6\u30ed\u30a4\u30c9\u958b\u59cb\u306b\u5148\u7acb\u3061\u3001\u7279\u306b\u611f\u67d3\u75c7\u306a\u3069\u306e\u91cd\u8981\u306a\u9451\u5225\u75be\u60a3\u3092\u5341\u5206\u306b\u8a55\u4fa1\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"562\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-133.png\" alt=\"\u901a\u5e38\u306eCAA\u3068CAA\u95a2\u9023\u708e\u75c7\u306b\u304a\u3051\u308b\u8133\u8840\u7ba1\u58c1\u306eA\u03b2\u6c88\u7740\u3001\u708e\u75c7\u7d30\u80de\u6d78\u6f64\u3001\u8133\u6d6e\u816b\u306e\u6bd4\u8f03\u6a21\u5f0f\u56f3\u3002\" class=\"wp-image-9375\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-133.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-133-400x281.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-133-768x539.png 768w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u56f3\uff1a\u901a\u5e38\u306eCAA\u3068CAA\u95a2\u9023\u708e\u75c7\uff08CAA-ri\uff09\u306e\u75c5\u614b\u6bd4\u8f03\u3002\u901a\u5e38\u306eCAA\u3067\u306f\u8133\u8840\u7ba1\u58c1\u3078\u306eA\u03b2\u6c88\u7740\u3068\u8840\u7ba1\u58c1\u969c\u5bb3\u304c\u4e2d\u5fc3\u3068\u306a\u308b\u3002\u4e00\u65b9\u3001CAA-ri\u3067\u306fA\u03b2\u6c88\u7740\u8840\u7ba1\u5468\u56f2\u3078\u306e\u708e\u75c7\u7d30\u80de\u6d78\u6f64\u3084\u6d6e\u816b\u6027\u5909\u5316\u304c\u52a0\u308f\u308a\u3001\u4e9c\u6025\u6027\u306e\u8133\u75c7\u3084\u5c40\u6240\u795e\u7d4c\u75c7\u72b6\u3092\u5448\u3059\u308b\u3002\u9ad8\u7528\u91cf\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u306a\u3069\u306e\u514d\u75ab\u6291\u5236\u6cbb\u7642\u306b\u3088\u308b\u81e8\u5e8a\u7684\u30fb\u753b\u50cf\u7684\u6539\u5584\u304c\u89b3\u5bdf\u7814\u7a76\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">10\uff0eCAA\u95a2\u9023\u708e\u75c7\u3068ARIA\uff1a\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u6cbb\u7642\u3068\u306e\u91cd\u8981\u306a\u63a5\u70b9<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fd1\u5e74\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u5bfe\u3059\u308b\u6297\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u6297\u4f53\u85ac\u304c\u81e8\u5e8a\u5c0e\u5165\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4ee3\u8868\u7684\u306a\u85ac\u5264\u306b\u306f\u30ec\u30ab\u30cd\u30de\u30d6\u3084\u30c9\u30ca\u30cd\u30de\u30d6\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u6cbb\u7642\u3067\u306f\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u95a2\u9023\u753b\u50cf\u7570\u5e38\uff08Amyloid-Related Imaging Abnormalities\uff1aARIA\uff09\u304c\u91cd\u8981\u306a\u6709\u5bb3\u4e8b\u8c61\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">ARIA\u306b\u306f\u4e3b\u306b\u3001\u6d6e\u816b\u3084\u6ef2\u51fa\u6027\u5909\u5316\u3092\u793a\u3059ARIA-E\u3068\u3001\u5fae\u5c0f\u51fa\u8840\u3084\u8868\u5728\u6027\u9244\u6c88\u7740\u306a\u3069\u306e\u51fa\u8840\u6027\u5909\u5316\u3092\u793a\u3059ARIA-H\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u306a\u305cCAA\u3068ARIA\u304c\u95a2\u9023\u3059\u308b\u306e\u304b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">CAA-ri\u3068ARIA\u306f\u3001\u81e8\u5e8a\u75c7\u72b6\u3001MRI\u6240\u898b\u3001\u75c5\u7406\u5b66\u7684\u7279\u5fb4\u306b\u5171\u901a\u70b9\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA-ri\u3067\u306f\u3001\u8840\u7ba1\u58c1\u306b\u6c88\u7740\u3057\u305fA\u03b2\u306b\u5bfe\u3059\u308b\u5185\u56e0\u6027\u306e\u514d\u75ab\u53cd\u5fdc\u304c\u95a2\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u6297A\u03b2\u6297\u4f53\u85ac\u306b\u3088\u308b\u6cbb\u7642\u3067\u306f\u3001\u6295\u4e0e\u3055\u308c\u305f\u6297\u4f53\u304c\u8840\u7ba1\u58c1\u306b\u95a2\u9023\u3059\u308b\u30a2\u30df\u30ed\u30a4\u30c9\u306b\u4f5c\u7528\u3057\u3001\u8840\u7ba1\u5468\u56f2\u306e\u708e\u75c7\u3084\u900f\u904e\u6027\u5909\u5316\u306b\u95a2\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u305f\u3081\u3001NEJM\u7dcf\u8aac\u3067\u306f\u3001ARIA\u304cCAA-ri\u306b\u985e\u4f3c\u3059\u308b\u533b\u539f\u6027\u306e\u708e\u75c7\u53cd\u5fdc\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u8ad6\u3058\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u4e21\u8005\u304c\u5b8c\u5168\u306b\u540c\u3058\u75c5\u614b\u3067\u3042\u308b\u3053\u3068\u304c\u8a3c\u660e\u3055\u308c\u305f\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u5171\u901a\u3059\u308b\u6a5f\u5e8f\u3092\u6709\u3059\u308b\u3068\u3044\u3046\u4eee\u8aac\u6bb5\u968e\u306e\u90e8\u5206\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001MRI\u3067\u5fae\u5c0f\u51fa\u8840\u3084\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u3092\u8a8d\u3081\u308b\u60a3\u8005\u3067\u306f\u3001\u6297A\u03b2\u514d\u75ab\u7642\u6cd5\u306b\u4f34\u3046ARIA\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6297A\u03b2\u6297\u4f53\u85ac\u306e\u4f7f\u7528\u5224\u65ad<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306e\u7dcf\u8aac\u3067\u306f\u3001\u5fae\u5c0f\u51fa\u8840\u304c4\u500b\u4ee5\u4e0b\u306e\u60a3\u8005\u306b\u3064\u3044\u3066\u3001\u500b\u5225\u306e\u30ea\u30b9\u30af\u3068\u5229\u76ca\u3092\u5341\u5206\u306b\u691c\u8a0e\u3057\u305f\u4e0a\u3067\u6cbb\u7642\u5bfe\u8c61\u3068\u306a\u308a\u5f97\u308b\u3053\u3068\u304c\u7d39\u4ecb\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u306fCAA\u3092\u7591\u3046\u60a3\u8005\u5168\u54e1\u306b\u6cbb\u7642\u304c\u63a8\u5968\u3055\u308c\u308b\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5b9f\u969b\u306e\u6cbb\u7642\u9069\u5fdc\u306f\u3001\u85ac\u5264\u3054\u3068\u306e\u627f\u8a8d\u6761\u4ef6\u3001\u9069\u6b63\u4f7f\u7528\u6307\u91dd\u3001\u51fa\u8840\u6b74\u3001MRI\u6240\u898b\u3001APOE\u907a\u4f1d\u5b50\u578b\u306a\u3069\u306b\u57fa\u3065\u3044\u3066\u5224\u65ad\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u3001\u5fae\u5c0f\u51fa\u8840\u306e\u500b\u6570\u3060\u3051\u3067\u306a\u304f\u3001\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u306e\u6709\u7121\u3001\u65e2\u5f80\u8133\u51fa\u8840\u3001\u6297\u51dd\u56fa\u7642\u6cd5\u306e\u5fc5\u8981\u6027\u306a\u3069\u306e\u8a55\u4fa1\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"562\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-134.png\" alt=\"CAA\u95a2\u9023\u708e\u75c7\u3068\u6297\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u6297\u4f53\u85ac\u306b\u3088\u308bARIA-E\u30fbARIA-H\u306e\u63a8\u5b9a\u75c5\u614b\u3092\u6bd4\u8f03\u3057\u305f\u533b\u5b66\u7684\u6a21\u5f0f\u56f3\u3002\" class=\"wp-image-9378\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-134.png 800w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-134-400x281.png 400w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/10\/image-134-767x539.png 767w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u56f3\uff1aCAA\u95a2\u9023\u708e\u75c7\uff08CAA-ri\uff09\u3068\u6297A\u03b2\u514d\u75ab\u7642\u6cd5\u306b\u4f34\u3046\u30a2\u30df\u30ed\u30a4\u30c9\u95a2\u9023\u753b\u50cf\u7570\u5e38\uff08ARIA\uff09\u306e\u63a8\u5b9a\u75c5\u614b\u30e2\u30c7\u30eb\u3002CAA-ri\u3067\u306f\u8840\u7ba1\u58c1A\u03b2\u306b\u5bfe\u3059\u308b\u5185\u56e0\u6027\u514d\u75ab\u5fdc\u7b54\u304c\u95a2\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u4e00\u65b9\u3001ARIA\u3067\u306f\u6cbb\u7642\u7528\u6297\u4f53\u3092\u4ecb\u3057\u305f\u8840\u7ba1\u58c1\u304a\u3088\u3073\u8840\u7ba1\u5468\u56f2\u306e\u53cd\u5fdc\u304c\u95a2\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u4e21\u8005\u306f\u81e8\u5e8a\u75c7\u72b6\u3001MRI\u6240\u898b\u3001\u75c5\u7406\u5b66\u7684\u7279\u5fb4\u3092\u5171\u6709\u3059\u308b\u304c\u3001\u5b8c\u5168\u306b\u540c\u4e00\u306e\u6a5f\u5e8f\u3067\u3042\u308b\u3053\u3068\u306f\u78ba\u7acb\u3055\u308c\u3066\u3044\u306a\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">11\uff0e\u4eca\u5f8c\u306e\u6cbb\u7642\u958b\u767a\uff1aCAA\u305d\u306e\u3082\u306e\u306e\u9032\u884c\u3092\u6291\u3048\u308b\u3053\u3068\u306f\u3067\u304d\u308b\u306e\u304b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u73fe\u5728\u3001\u4e00\u822c\u7684\u306aCAA\u306b\u5bfe\u3057\u3066\u3001\u8840\u7ba1\u58c1\u306b\u6c88\u7740\u3057\u305fA\u03b2\u3092\u5b89\u5168\u304b\u3064\u78ba\u5b9f\u306b\u9664\u53bb\u3057\u3001\u8133\u51fa\u8840\u3092\u4e88\u9632\u3067\u304d\u308b\u3068\u78ba\u7acb\u3055\u308c\u305f\u75be\u60a3\u4fee\u98fe\u6cbb\u7642\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001CAA\u306e\u75c5\u614b\u304c\u6570\u5341\u5e74\u5358\u4f4d\u3067\u9032\u884c\u3059\u308b\u3053\u3068\u306f\u3001\u65e9\u671f\u8a3a\u65ad\u3068\u4ecb\u5165\u306e\u53ef\u80fd\u6027\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306eNEJM\u7dcf\u8aac\u3067\u306f\u3001\u4eca\u5f8c\u306e\u6cbb\u7642\u6226\u7565\u3068\u3057\u3066\u3001A\u03b2\u7523\u751f\u306e\u6291\u5236\u3001A\u03b2\u9664\u53bb\u306e\u4fc3\u9032\u3001A\u03b2\u6c88\u7740\u306b\u3088\u308b\u8840\u7ba1\u58c1\u969c\u5bb3\u306e\u6291\u5236\u304c\u6319\u3052\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">APP\u3092\u6a19\u7684\u3068\u3057\u305fsiRNA\u6cbb\u7642<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u7814\u7a76\u306e\u4e00\u3064\u304c\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u524d\u99c6\u4f53\u30bf\u30f3\u30d1\u30af\u8cea\uff08APP\uff09\u3092\u6a19\u7684\u3068\u3057\u305fshort interfering RNA\uff08siRNA\uff09\u6cbb\u7642\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">APP\u306e\u767a\u73fe\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u3001\u4e0b\u6d41\u306eA\u03b2\u7523\u751f\u3092\u6e1b\u3089\u3057\u3001CAA\u306e\u9032\u884c\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NEJM\u7dcf\u8aac\u3067\u306f\u3001C16\u7d50\u5408\u578bsiRNA\u3092\u7528\u3044\u305f\u7b2c2\u76f8\u81e8\u5e8a\u8a66\u9a13\uff08NCT06393712\uff09\u304c\u7d39\u4ecb\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a66\u9a13\u5bfe\u8c61\u306b\u306f\u3001\u75c7\u5019\u6027\u306e\u5b64\u767a\u6027CAA\u60a3\u8005\u306e\u307b\u304b\u3001\u767a\u75c7\u524d\u307e\u305f\u306f\u75c7\u5019\u6027\u306eDutch-type\u907a\u4f1d\u6027CAA\u60a3\u8005\u304c\u542b\u307e\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u306e\u7814\u7a76\u306fCAA\u306e\u75c5\u614b\u9032\u884c\u3092\u6291\u5236\u3067\u304d\u308b\u304b\u3092\u691c\u8a3c\u3059\u308b\u6bb5\u968e\u3067\u3042\u308a\u3001\u8133\u51fa\u8840\u4e88\u9632\u52b9\u679c\u3084\u9577\u671f\u7684\u5b89\u5168\u6027\u304c\u78ba\u7acb\u3055\u308c\u305f\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u5f8c\u306f\u3001A\u03b2\u7523\u751f\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u5b9f\u969b\u306b\u8840\u7ba1\u53cd\u5fdc\u6027\u3001MRI\u75c5\u5909\u3001\u8a8d\u77e5\u6a5f\u80fd\u3001\u8133\u51fa\u8840\u30ea\u30b9\u30af\u304c\u6539\u5584\u3059\u308b\u304b\u3092\u691c\u8a3c\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">12\uff0e\u81e8\u5e8a\u3078\u306e\u793a\u5506\uff1aCAA\u3092\u3069\u306e\u3088\u3046\u306b\u8a3a\u7642\u3078\u751f\u304b\u3059\u304b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306eNEJM\u7dcf\u8aac\u304b\u3089\u3001\u5b9f\u969b\u306e\u81e8\u5e8a\u3067\u91cd\u8981\u3068\u306a\u308b\u70b9\u3092\u307e\u3068\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b2c\u4e00\u306b\u3001\u9ad8\u9f62\u8005\u306e\u8133\u8449\u51fa\u8840\u3084\u591a\u767a\u6027\u8133\u8449\u5fae\u5c0f\u51fa\u8840\u3067\u306f\u3001CAA\u3092\u91cd\u8981\u306a\u9451\u5225\u8a3a\u65ad\u3068\u3057\u3066\u8003\u3048\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002MRI\u306eT2*\u753b\u50cf\u3084SWI\u753b\u50cf\u3067\u3001\u51fa\u8840\u6027\u75c5\u5909\u306e\u5206\u5e03\u3092\u78ba\u8a8d\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b2c\u4e8c\u306b\u3001CAA\u306f\u8133\u51fa\u8840\u3092\u5f15\u304d\u8d77\u3053\u3059\u3060\u3051\u3067\u306a\u304f\u3001\u767d\u8cea\u75c5\u5909\u3084\u5fae\u5c0f\u6897\u585e\u3092\u4ecb\u3057\u3066\u3001\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u8a8d\u77e5\u75c7\u8a3a\u7642\u306b\u304a\u3044\u3066\u3082\u8133\u5c0f\u8840\u7ba1\u75c5\u5909\u306e\u8a55\u4fa1\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b2c\u4e09\u306b\u3001CAA\u60a3\u8005\u306b\u5bfe\u3059\u308b\u6297\u8840\u6813\u7642\u6cd5\u306e\u5224\u65ad\u3067\u306f\u3001\u5fc3\u539f\u6027\u8133\u585e\u6813\u75c7\u306e\u4e88\u9632\u5229\u76ca\u3068\u8133\u51fa\u8840\u30ea\u30b9\u30af\u3092\u500b\u5225\u306b\u6bd4\u8f03\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u65e2\u5f80\u8133\u51fa\u8840\u3084\u76ae\u8cea\u8868\u5728\u6027\u9244\u6c88\u7740\u306e\u6709\u7121\u306f\u91cd\u8981\u306a\u5224\u65ad\u6750\u6599\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b2c\u56db\u306b\u3001CAA-ri\u306f\u514d\u75ab\u6291\u5236\u7642\u6cd5\u306b\u53cd\u5fdc\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u4e9c\u6025\u6027\u306e\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3001\u982d\u75db\u3001\u3051\u3044\u308c\u3093\u3001\u975e\u5bfe\u79f0\u6027\u767d\u8cea\u75c5\u5909\u3092\u8a8d\u3081\u308b\u60a3\u8005\u3067\u306f\u3001\u9451\u5225\u306b\u6319\u3052\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b2c\u4e94\u306b\u3001\u6297A\u03b2\u6297\u4f53\u85ac\u304c\u666e\u53ca\u3059\u308b\u4e2d\u3067\u3001CAA\u306b\u7279\u5fb4\u7684\u306a\u5fae\u5c0f\u51fa\u8840\u3084\u9244\u6c88\u7740\u306f\u3001ARIA\u30ea\u30b9\u30af\u3092\u8a55\u4fa1\u3059\u308b\u4e0a\u3067\u3082\u91cd\u8981\u306a\u610f\u5473\u3092\u6301\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306e\u8a3a\u7642\u306f\u3001\u5358\u306b\u8133\u51fa\u8840\u306e\u539f\u56e0\u3092\u8a3a\u65ad\u3059\u308b\u3053\u3068\u306b\u3068\u3069\u307e\u3089\u305a\u3001\u5c06\u6765\u306e\u51fa\u8840\u30ea\u30b9\u30af\u3001\u8a8d\u77e5\u6a5f\u80fd\u3078\u306e\u5f71\u97ff\u3001\u6297\u8840\u6813\u7642\u6cd5\u3001\u514d\u75ab\u6cbb\u7642\u306e\u5b89\u5168\u6027\u3092\u7dcf\u5408\u7684\u306b\u5224\u65ad\u3059\u308b\u6bb5\u968e\u3078\u3068\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">13\uff0e\u307e\u3068\u3081<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u30a2\u30df\u30ed\u30a4\u30c9\u30a2\u30f3\u30ae\u30aa\u30d1\u30c1\u30fc\uff08CAA\uff09\u306f\u3001\u8133\u306e\u5c0f\u8840\u7ba1\u58c1\u3078\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u6c88\u7740\u3092\u7279\u5fb4\u3068\u3059\u308b\u3001\u52a0\u9f62\u306b\u95a2\u9023\u3057\u305f\u8133\u5c0f\u8840\u7ba1\u75be\u60a3\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u8449\u51fa\u8840\u3084\u5fae\u5c0f\u51fa\u8840\u3060\u3051\u3067\u306a\u304f\u3001\u9032\u884c\u6027\u306e\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3084\u4e00\u904e\u6027\u5c40\u6240\u795e\u7d4c\u75c7\u72b6\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Boston criteria version 2.0\u306b\u3088\u308aMRI\u6240\u898b\u306b\u57fa\u3065\u304f\u8a3a\u65ad\u304c\u53ef\u80fd\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u660e\u3089\u304b\u306a\u51fa\u8840\u6027\u75c5\u5909\u3092\u4f34\u308f\u306a\u3044\u65e9\u671fCAA\u306e\u691c\u51fa\u306b\u306f\u8ab2\u984c\u304c\u6b8b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p 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href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-1301\/?utm_source=chatgpt.com\">\u5fc3\u623f\u7d30\u52d5\u30a2\u30d6\u30ec\u30fc\u30b7\u30e7\u30f3\u6210\u529f\u5f8c\u3001\u6297\u51dd\u56fa\u7642\u6cd5\u306f\u5fc5\u8981\u304b\uff1fOCEAN\u8a66\u9a13<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CAA\u306b\u5fc3\u623f\u7d30\u52d5\u3092\u5408\u4f75\u3057\u305f\u5834\u5408\u3001\u6297\u51dd\u56fa\u7642\u6cd5\u306b\u3088\u308b\u8133\u585e\u6813\u75c7\u4e88\u9632\u3068\u982d\u84cb\u5185\u51fa\u8840\u30ea\u30b9\u30af\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u91cd\u8981\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u5fc3\u623f\u7d30\u52d5\u30a2\u30d6\u30ec\u30fc\u30b7\u30e7\u30f3\u5f8c\u306e\u6297\u51dd\u56fa\u7642\u6cd5\u3092\u691c\u8a3c\u3057\u305fOCEAN\u8a66\u9a13\u3092\u53d6\u308a\u4e0a\u3052\u3066\u3044\u307e\u3059\u3002CAA\u60a3\u8005\u3092\u76f4\u63a5\u5bfe\u8c61\u3068\u3057\u305f\u8a66\u9a13\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u6297\u8840\u6813\u7642\u6cd5\u306e\u5229\u76ca\u3068\u4e0d\u5229\u76ca\u3092\u500b\u5225\u306b\u5224\u65ad\u3059\u308b\u91cd\u8981\u6027\u3092\u88dc\u5b8c\u3059\u308b\u5185\u5bb9\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u25a0\u4e00\u6b21\u6587\u732e\u30fb\u51fa\u5178<\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<h3 class=\"wp-block-heading\">\u4e2d\u5fc3\u6587\u732e<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Greenberg SM. Cerebral Amyloid Angiopathy. N Engl J Med. 2026;394:1836\u20131845.<a href=\"https:\/\/doi.org\/10.1056\/NEJMra2411298?utm_source=chatgpt.com\">https:\/\/doi.org\/10.1056\/NEJMra2411298<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u8a3a\u65ad\u30fb\u75ab\u5b66\u30fb\u6cbb\u7642\u306e\u6839\u62e0\u3068\u306a\u308b\u4e3b\u8981\u7814\u7a76<\/h3>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Charidimou A, et al. The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study. Lancet Neurol. 2022;21:714\u2013725. <a href=\"https:\/\/doi.org\/10.1016\/S1474-4422(22)00208-3?utm_source=chatgpt.com\">DOI<\/a><\/li>\n\n\n\n<li>J\u00e4kel L, et al. Prevalence of cerebral amyloid angiopathy: a systematic review and meta-analysis. Alzheimers Dement. 2022;18:10\u201328.<\/li>\n\n\n\n<li>Charidimou A, et al. Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds: a meta-analysis. Neurology. 2017;89:820\u2013829.<\/li>\n\n\n\n<li>Regenhardt RW, et al. Association between Immunosuppressive Treatment and Outcomes of Cerebral Amyloid Angiopathy\u2013Related Inflammation. JAMA Neurol. 2020;77:1261\u20131269.<\/li>\n\n\n\n<li>Greenberg SM, et al. 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage. Stroke. 2022;53:e282\u2013e361.<\/li>\n<\/ol>\n<\/blockquote>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23%\">\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/84f9b1a365bb2c08a7e4b50359f34012-600x600.png\" alt=\"\" class=\"wp-image-8240\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/84f9b1a365bb2c08a7e4b50359f34012-600x600.png 600w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/08\/84f9b1a365bb2c08a7e4b50359f34012-150x150.png 150w, 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