{"id":9920,"date":"2026-11-08T17:17:51","date_gmt":"2026-11-08T08:17:51","guid":{"rendered":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/?p=9920"},"modified":"2026-11-08T17:20:30","modified_gmt":"2026-11-08T08:20:30","slug":"late-onset-multiple-sclerosis-tumefactive-demyelination-nejm-2026","status":"publish","type":"post","link":"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/late-onset-multiple-sclerosis-tumefactive-demyelination-nejm-2026\/","title":{"rendered":"64\u6b73\u5973\u6027\u306e\u8a18\u61b6\u969c\u5bb3\u30fb\u8ee2\u5012\u304b\u3089\u5224\u660e\u3057\u305f\u591a\u767a\u6027\u786c\u5316\u75c7\uff5c\u8133MRI\u306eOpen-ring sign\u3068\u8133\u751f\u691c\u3010NEJM 2026\u3011"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\">\u5026\u6020\u611f\u3068\u4e0d\u7720\u304b\u3089\u59cb\u307e\u3063\u305f\u795e\u7d4c\u75c7\u72b6\u3002\u305d\u306e\u80cc\u666f\u306b\u591a\u6570\u306e\u8133\u767d\u8cea\u75c5\u5909\u304c\u96a0\u308c\u3066\u3044\u305f<\/h3>\n\n\n\n<p 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class=\"wp-block-paragraph\"><strong>\u56f3\u8aac\uff1a64\u6b73\u5973\u6027\u306b\u304a\u3051\u308b\u795e\u7d4c\u75c7\u72b6\u306e\u9032\u884c\u3068\u8a3a\u65ad\u306b\u81f3\u308b\u7d4c\u904e<\/strong>\u3002\u5026\u6020\u611f\u304b\u3089\u59cb\u307e\u308a\u3001\u77ed\u671f\u9593\u3067\u6ce8\u610f\u969c\u5bb3\u3001\u6b69\u884c\u969c\u5bb3\u3001\u8ee2\u5012\u304c\u51fa\u73fe\u3057\u305f\u3002\u982d\u90e8MRI\u3067\u591a\u6570\u306e\u30ea\u30f3\u30b0\u72b6\u9020\u5f71\u75c5\u5909\u304c\u8a8d\u3081\u3089\u308c\u3001\u611f\u67d3\u75c7\u3001\u60aa\u6027\u816b\u760d\u3001\u8131\u9ac4\u6027\u75be\u60a3\u306e\u9451\u5225\u304c\u884c\u308f\u308c\u305f\u3002\u8133\u751f\u691c\u3067\u306f\u8131\u9ac4\u75c5\u5909\u304c\u78ba\u8a8d\u3055\u308c\u3001\u9ac4\u6db2\u30aa\u30ea\u30b4\u30af\u30ed\u30fc\u30ca\u30eb\u30d0\u30f3\u30c9\u304a\u3088\u3073\u8ffd\u52a0MRI\u6240\u898b\u3092\u7dcf\u5408\u3057\u3066\u591a\u767a\u6027\u786c\u5316\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u305f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2\uff0e\u982d\u90e8MRI\uff1a\u591a\u6570\u306e\u30ea\u30f3\u30b0\u72b6\u9020\u5f71\u75c5\u5909\u304c\u767a\u898b\u3055\u308c\u305f<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u982d\u90e8MRI\u3067\u306f\u3001\u5927\u8133\u534a\u7403\u306e\u767d\u8cea\u306b\u591a\u6570\u306e\u7570\u5e38\u75c5\u5909\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u306a\u6240\u898b\u306f\u4ee5\u4e0b\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5927\u8133\u30c6\u30f3\u30c8\u4e0a\u767d\u8cea\u306b\u591a\u6570\u306eFLAIR\u9ad8\u4fe1\u53f7\u75c5\u5909<\/li>\n\n\n\n<li>\u75c5\u5909\u5185\u90e8\u306eT2\u9ad8\u4fe1\u53f7<\/li>\n\n\n\n<li>\u75c5\u5909\u5468\u56f2\u306eT2\u4f4e\u4fe1\u53f7\u30ea\u30e0<\/li>\n\n\n\n<li>\u8efd\u5ea6\u306e\u5468\u56f2\u6d6e\u816b<\/li>\n\n\n\n<li>\u9020\u5f71MRI\u3067\u30ea\u30f3\u30b0\u72b6\u5897\u5f37\u52b9\u679c<\/li>\n\n\n\n<li>\u4e00\u90e8\u306e\u75c5\u5909\u306bopen-ring enhancement<\/li>\n\n\n\n<li>\u62e1\u6563\u5236\u9650\u306a\u3057<\/li>\n\n\n\n<li>\u660e\u3089\u304b\u306a\u78c1\u5316\u7387\u7570\u5e38\u306a\u3057<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">\u30ea\u30f3\u30b0\u72b6\u9020\u5f71\u75c5\u5909\u3068\u306f\u4f55\u304b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9020\u5f71MRI\u3067\u75c5\u5909\u306e\u5468\u56f2\u304c\u8f2a\u306e\u3088\u3046\u306b\u5897\u5f37\u3055\u308c\u308b\u6240\u898b\u3092\u3001\u30ea\u30f3\u30b0\u72b6\u9020\u5f71\uff08ring enhancement\uff09\u3068\u547c\u3073\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u6240\u898b\u306f\u3001\u8840\u6db2\u8133\u95a2\u9580\u306e\u7834\u7dbb\u306a\u3069\u3092\u53cd\u6620\u3059\u308b\u3082\u306e\u3067\u3001\u539f\u56e0\u306f\u4e00\u3064\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4ee3\u8868\u7684\u306a\u9451\u5225\u75be\u60a3\u306b\u306f\u3001\u4ee5\u4e0b\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u8ee2\u79fb\u6027\u8133\u816b\u760d<\/li>\n\n\n\n<li>\u539f\u767a\u6027\u8133\u816b\u760d<\/li>\n\n\n\n<li>\u8133\u81bf\u760d<\/li>\n\n\n\n<li>\u30c8\u30ad\u30bd\u30d7\u30e9\u30ba\u30de\u8133\u75c7<\/li>\n\n\n\n<li>\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u6027\u75c5\u5909<\/li>\n\n\n\n<li>\u4e00\u90e8\u306e\u708e\u75c7\u6027\u30fb\u8840\u7ba1\u6027\u75be\u60a3<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u30ea\u30f3\u30b0\u72b6\u9020\u5f71\u75c5\u5909\u3092\u898b\u305f\u3060\u3051\u3067\u60aa\u6027\u816b\u760d\u3068\u8a3a\u65ad\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u591a\u6570\u306e\u75c5\u5909\u304c\u5b58\u5728\u3057\u307e\u3057\u305f\u304c\u3001\u5468\u56f2\u6d6e\u816b\u306f\u6bd4\u8f03\u7684\u8efd\u5ea6\u3067\u3001\u62e1\u6563\u5236\u9650\u3082\u8a8d\u3081\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u6240\u898b\u306f\u9451\u5225\u8a3a\u65ad\u3092\u9032\u3081\u308b\u3046\u3048\u3067\u91cd\u8981\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3\uff0eOpen-ring enhancement\uff1a\u8131\u9ac4\u3092\u793a\u5506\u3059\u308bMRI\u6240\u898b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eca\u56de\u306eMRI\u3067\u7279\u306b\u6ce8\u76ee\u3055\u308c\u305f\u306e\u304c\u3001open-ring enhancement\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u901a\u5e38\u306e\u30ea\u30f3\u30b0\u72b6\u9020\u5f71\u3067\u306f\u3001\u9020\u5f71\u3055\u308c\u308b\u90e8\u5206\u304c\u75c5\u5909\u3092\u307b\u307c\u4e00\u5468\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001open-ring enhancement\u3067\u306f\u3001\u30ea\u30f3\u30b0\u306e\u4e00\u90e8\u304c\u9014\u5207\u308c\u305f\u3088\u3046\u306a\u5f62\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u3067\u306f\u3001\u3053\u306e\u3088\u3046\u306a\u4e0d\u5b8c\u5168\u306a\u30ea\u30f3\u30b0\u72b6\u9020\u5f71\u304c\u8a8d\u3081\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u306a\u305c\u8131\u9ac4\u6027\u75c5\u5909\u3067open-ring sign\u304c\u751f\u3058\u308b\u306e\u304b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u767a\u6027\u786c\u5316\u75c7\u3067\u306f\u3001\u514d\u75ab\u7cfb\u304c\u4e2d\u67a2\u795e\u7d4c\u306e\u9ac4\u9798\uff08\u30df\u30a8\u30ea\u30f3\uff09\u3092\u969c\u5bb3\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6d3b\u52d5\u6027\u306e\u8131\u9ac4\u75c5\u5909\u3067\u306f\u3001\u708e\u75c7\u306b\u4f34\u3046\u8840\u6db2\u8133\u95a2\u9580\u306e\u7834\u7dbb\u304c\u751f\u3058\u3001\u9020\u5f71\u5264\u304c\u75c5\u5909\u306e\u4e00\u90e8\u306b\u96c6\u7a4d\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u708e\u75c7\u306e\u6d3b\u52d5\u6027\u3084\u75c5\u5909\u306e\u9032\u5c55\u65b9\u5411\u304c\u5747\u4e00\u3067\u306a\u3044\u305f\u3081\u3001\u4e0d\u5b8c\u5168\u306a\u30ea\u30f3\u30b0\u72b6\u9020\u5f71\u3068\u3057\u3066\u63cf\u51fa\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Open-ring sign\u306f\u8131\u9ac4\u6027\u75c5\u5909\u3092\u652f\u6301\u3059\u308b\u6240\u898b\u3067\u3059\u304c\u3001\u5358\u72ec\u3067\u8a3a\u65ad\u3092\u78ba\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Open-ring sign\u306e\u8a3a\u65ad\u6027\u80fd<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u5831\u544a\u3067\u5f15\u7528\u3055\u308c\u305f2018\u5e74\u306e\u7cfb\u7d71\u7684\u30ec\u30d3\u30e5\u30fc\u30fb\u30e1\u30bf\u89e3\u6790\u3067\u306f\u3001\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u75c5\u5909\u306b\u304a\u3051\u308bopen-ring sign\u306e\u7d71\u5408\u51fa\u73fe\u5272\u5408\u306f\u7d0435\uff05\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u8133\u816b\u760d\u3068\u306e\u9451\u5225\u306b\u304a\u3051\u308b\u7d71\u5408\u7279\u7570\u5ea6\u306f95\uff05\u3092\u8d85\u3048\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3064\u307e\u308a\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Open-ring sign\u304c\u8a8d\u3081\u3089\u308c\u308c\u3070\u8131\u9ac4\u6027\u75c5\u5909\u3092\u5f37\u304f\u7591\u3046\u6839\u62e0\u306b\u306a\u308b<\/li>\n\n\n\n<li>\u3057\u304b\u3057\u3001\u8131\u9ac4\u6027\u75c5\u5909\u306e\u3059\u3079\u3066\u3067\u8a8d\u3081\u3089\u308c\u308b\u308f\u3051\u3067\u306f\u306a\u3044<\/li>\n\n\n\n<li>Open-ring sign\u304c\u306a\u3044\u3053\u3068\u3092\u7406\u7531\u306b\u8131\u9ac4\u6027\u75c5\u5909\u3092\u5426\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u306a\u3044<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u306a\u304a\u3001MRI\u6240\u898b\u306f\u64ae\u50cf\u6761\u4ef6\u3084\u75c5\u5909\u306e\u6d3b\u52d5\u6027\u306b\u3088\u3063\u3066\u5909\u5316\u3057\u3001\u816b\u760d\u6027\u75c5\u5909\u306a\u3069\u3068\u306e\u6240\u898b\u306e\u91cd\u8907\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001\u753b\u50cf\u6240\u898b\u3060\u3051\u3067\u306a\u304f\u3001\u81e8\u5e8a\u7d4c\u904e\u3001\u9ac4\u6db2\u691c\u67fb\u3001\u5168\u8eab\u691c\u7d22\u306a\u3069\u3092\u7d71\u5408\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"781\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-26-781x600.png\" alt=\"64\u6b73\u5973\u6027\u306e\u982d\u90e8CT\u304a\u3088\u3073MRI\u3002\u591a\u767a\u6027\u767d\u8cea\u75c5\u5909\u3092\u8a8d\u3081\u3001\u9020\u5f71MRI\u306e\u4e00\u90e8\u3067open-ring enhancement\u304c\u78ba\u8a8d\u3055\u308c\u308b\u3002\" class=\"wp-image-9923\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-26-781x600.png 781w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-26-391x300.png 391w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-26-767x589.png 767w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-26.png 800w\" sizes=\"auto, (max-width: 781px) 100vw, 781px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac\uff1a64\u6b73\u5973\u6027\u306b\u8a8d\u3081\u3089\u308c\u305f\u591a\u767a\u6027\u8133\u767d\u8cea\u75c5\u5909<\/strong>\u3002\u5358\u7d14CT\u3067\u306f\u6563\u5728\u6027\u306e\u767d\u8cea\u4f4e\u5438\u53ce\u57df\u3092\u8a8d\u3081\u3001MRI\u306eFLAIR\u30fbT2\u5f37\u8abf\u753b\u50cf\u3067\u306f\u5468\u56f2\u306b\u8efd\u5ea6\u306e\u6d6e\u816b\u3092\u4f34\u3046\u591a\u767a\u6027\u767d\u8cea\u75c5\u5909\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\u9020\u5f71MRI\u3067\u306f\u4e3b\u306b\u30ea\u30f3\u30b0\u72b6\u5897\u5f37\u52b9\u679c\u3092\u793a\u3057\u3001\u4e00\u90e8\u306e\u75c5\u5909\u3067\u306f\u30ea\u30f3\u30b0\u304c\u4e0d\u5b8c\u5168\u3068\u306a\u308bopen-ring enhancement\u3092\u8a8d\u3081\u305f\u3002\u3053\u306e\u6240\u898b\u306f\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u3092\u793a\u5506\u3059\u308b\u304c\u3001\u60aa\u6027\u816b\u760d\u3084\u611f\u67d3\u75c7\u306a\u3069\u3068\u306e\u9451\u5225\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u753b\u50cf\u51fa\u5178\uff1aBhattacharyya S, et al. N Engl J Med. 2026;394:2041\u20132050. DOI: 10.1056\/NEJMcpc2517865.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4\uff0e\u9451\u5225\u8a3a\u65ad\uff1a\u306a\u305c\u8133\u816b\u760d\u3084\u611f\u67d3\u75c7\u3067\u306f\u306a\u304b\u3063\u305f\u306e\u304b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u75c7\u4f8b\u3067\u306f\u3001\u611f\u67d3\u75c7\u3001\u60aa\u6027\u816b\u760d\u3001\u8840\u7ba1\u6027\u75be\u60a3\u3001\u514d\u75ab\u4ecb\u5728\u6027\u75be\u60a3\u304c\u691c\u8a0e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u8133\u81bf\u760d\u30fb\u611f\u67d3\u75c7<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d30\u83cc\u6027\u8133\u81bf\u760d\u3067\u306f\u3001\u5178\u578b\u7684\u306b\u306f\u62e1\u6563\u5f37\u8abf\u753b\u50cf\u3067\u5f37\u3044\u62e1\u6563\u5236\u9650\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u591a\u6570\u306e\u30ea\u30f3\u30b0\u72b6\u9020\u5f71\u75c5\u5909\u306e\u3044\u305a\u308c\u306b\u3082\u660e\u3089\u304b\u306a\u62e1\u6563\u5236\u9650\u304c\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u767a\u71b1\u3001\u767d\u8840\u7403\u5897\u591a\u3001\u708e\u75c7\u53cd\u5fdc\u4e0a\u6607\u3082\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u7d30\u83cc\u6027\u8133\u81bf\u760d\u306e\u53ef\u80fd\u6027\u306f\u4f4e\u3044\u3068\u5224\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u6240\u898b\u3060\u3051\u3067\u3059\u3079\u3066\u306e\u611f\u67d3\u75c7\u3092\u5b8c\u5168\u306b\u9664\u5916\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u771f\u83cc\u611f\u67d3\u75c7\u3001\u5bc4\u751f\u866b\u611f\u67d3\u75c7\u3001JC\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306a\u3069\u3082\u9451\u5225\u306b\u542b\u307e\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u8ee2\u79fb\u6027\u8133\u816b\u760d<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u60a3\u8005\u306fBRCA2\u75c5\u7684\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u4fdd\u6709\u3057\u3066\u304a\u308a\u3001\u4e73\u304c\u3093\u306a\u3069\u306e\u60aa\u6027\u816b\u760d\u306e\u767a\u75c7\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u72b6\u614b\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u904e\u53bb\u306eCT\u691c\u67fb\u3067\u306f\u53f3\u4e0b\u8449\u306b5mm\u306e\u80ba\u7d50\u7bc0\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u8ee2\u79fb\u6027\u8133\u816b\u760d\u306f\u91cd\u8981\u306a\u9451\u5225\u8a3a\u65ad\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u4eca\u56de\u306e\u75c5\u5909\u306b\u306f\u4ee5\u4e0b\u306e\u7279\u5fb4\u304c\u3042\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u591a\u6570\u306e\u75c5\u5909\u306e\u5272\u306b\u795e\u7d4c\u75c7\u72b6\u304c\u6bd4\u8f03\u7684\u8efd\u3044<\/li>\n\n\n\n<li>\u7070\u767d\u8cea\u3068\u767d\u8cea\u306e\u5883\u754c\u90e8\u306b\u75c5\u5909\u304c\u96c6\u4e2d\u3057\u3066\u3044\u306a\u3044<\/li>\n\n\n\n<li>\u5468\u56f2\u6d6e\u816b\u304c\u8efd\u5ea6<\/li>\n\n\n\n<li>Open-ring enhancement\u3092\u4f34\u3046<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306f\u5178\u578b\u7684\u306a\u8133\u8ee2\u79fb\u3068\u306f\u7570\u306a\u308b\u6240\u898b\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5168\u8eabCT\u3067\u306f\u3001\u80ba\u7d50\u7bc0\u306f6\u304b\u6708\u524d\u3068\u6bd4\u8f03\u3057\u3066\u4e0d\u5909\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u5168\u8eabFDG-PET\u3067\u3082\u660e\u3089\u304b\u306a\u6d3b\u52d5\u6027\u60aa\u6027\u816b\u760d\u306f\u78ba\u8a8d\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u8ee2\u79fb\u3067\u306f\u3001\u539f\u767a\u816b\u760d\u306e\u7a2e\u985e\u3084\u75c5\u5909\u306e\u5206\u5e03\u3001\u9020\u5f71\u30d1\u30bf\u30fc\u30f3\u306a\u3069\u304c\u8a3a\u65ad\u306e\u624b\u304c\u304b\u308a\u306b\u306a\u308a\u307e\u3059\u3002\u5177\u4f53\u7684\u306a\u753b\u50cf\u6240\u898b\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-1234\/\" target=\"_blank\" rel=\"noopener\">\u80ba\u304c\u3093\u8133\u8ee2\u79fb\u306eCT\u30fbMRI\u6240\u898b\u3092\u89e3\u8aac\u3057\u305f\u75c7\u4f8b<\/a>\u3082\u53c2\u8003\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u4e2d\u67a2\u795e\u7d4c\u539f\u767a\u60aa\u6027\u30ea\u30f3\u30d1\u816b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u539f\u767a\u6027\u4e2d\u67a2\u795e\u7d4c\u30ea\u30f3\u30d1\u816b\u3082\u591a\u767a\u6027\u8133\u75c5\u5909\u306e\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u514d\u75ab\u6a5f\u80fd\u304c\u4fdd\u305f\u308c\u305f\u6210\u4eba\u3067\u306f\u3001\u6bd4\u8f03\u7684\u5747\u4e00\u306a\u9020\u5f71\u52b9\u679c\u3084\u62e1\u6563\u5236\u9650\u3092\u4f34\u3046\u3053\u3068\u304c\u591a\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u306eMRI\u6240\u898b\u306f\u5178\u578b\u7684\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u753b\u50cf\u3060\u3051\u3067\u5b8c\u5168\u306b\u9664\u5916\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u8840\u7ba1\u708e\u30fb\u8840\u6813\u6027\u75be\u60a3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e2d\u67a2\u795e\u7d4c\u8840\u7ba1\u708e\u3001\u6297\u30ea\u30f3\u8102\u8cea\u6297\u4f53\u75c7\u5019\u7fa4\u3001\u611f\u67d3\u6027\u5fc3\u5185\u819c\u708e\u306a\u3069\u3067\u3082\u3001\u591a\u767a\u6027\u306e\u8133\u75c5\u5909\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u672c\u75c7\u4f8b\u306eMRI\u3067\u306f\u3001\u7570\u306a\u308b\u6642\u671f\u306b\u5f62\u6210\u3055\u308c\u305f\u591a\u6570\u306e\u865a\u8840\u6027\u6897\u585e\u3092\u793a\u5506\u3059\u308b\u5178\u578b\u7684\u6240\u898b\u304c\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u660e\u3089\u304b\u306a\u5168\u8eab\u6027\u708e\u75c7\u6240\u898b\u3082\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001\u8840\u7ba1\u6027\u75be\u60a3\u306e\u53ef\u80fd\u6027\u306f\u76f8\u5bfe\u7684\u306b\u4f4e\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u539f\u767a\u6027\u4e2d\u67a2\u795e\u7d4c\u8840\u7ba1\u708e\u306f\u753b\u50cf\u6240\u898b\u304c\u591a\u5f69\u3067\u3042\u308a\u3001\u5b8c\u5168\u306b\u306f\u9664\u5916\u3067\u304d\u306a\u3044\u6bb5\u968e\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u9f62\u8005\u306e\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u3084\u6b69\u884c\u969c\u5bb3\u3067\u306f\u3001\u8133\u8840\u7ba1\u6027\u75be\u60a3\u3082\u91cd\u8981\u306a\u9451\u5225\u3068\u306a\u308a\u307e\u3059\u3002<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/cerebral-amyloid-angiopathy-caa\/\" target=\"_blank\" rel=\"noopener\">\u8133\u30a2\u30df\u30ed\u30a4\u30c9\u30a2\u30f3\u30ae\u30aa\u30d1\u30c1\u30fc\uff08CAA\uff09\u306eMRI\u8a3a\u65ad\u3068\u6cbb\u7642<\/a>\u3067\u306f\u3001\u5fae\u5c0f\u51fa\u8840\u3084\u708e\u75c7\u95a2\u9023\u75c5\u5909\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2464 \u514d\u75ab\u4ecb\u5728\u6027\u8131\u9ac4\u75be\u60a3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">MRI\u6240\u898b\u3068\u81e8\u5e8a\u7d4c\u904e\u304b\u3089\u3001\u8131\u9ac4\u6027\u75be\u60a3\u304c\u6709\u529b\u306a\u5019\u88dc\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u306a\u9451\u5225\u75be\u60a3\u306f\u6b21\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u591a\u767a\u6027\u786c\u5316\u75c7\uff08MS\uff09<\/li>\n\n\n\n<li>MOG\u6297\u4f53\u95a2\u9023\u75be\u60a3\uff08MOGAD\uff09<\/li>\n\n\n\n<li>\u8996\u795e\u7d4c\u810a\u9ac4\u708e\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u969c\u5bb3\uff08NMOSD\uff09<\/li>\n\n\n\n<li>\u6025\u6027\u6563\u5728\u6027\u8133\u810a\u9ac4\u708e\uff08ADEM\uff09<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u795e\u7d4c\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u306a\u3069\u306e\u708e\u75c7\u6027\u75be\u60a3\u3082\u9451\u5225\u306b\u542b\u307e\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u306b\u3064\u3044\u3066\u306f\u3001<a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-9306\/\" target=\"_blank\" rel=\"noopener\">\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u306e\u6700\u65b0\u8a3a\u65ad\u3068\u6cbb\u76422026<\/a>\u3067\u3082\u3001\u5168\u8eab\u6027\u75be\u60a3\u3068\u3057\u3066\u306e\u81d3\u5668\u8a55\u4fa1\u3068\u8a3a\u65ad\u306e\u8003\u3048\u65b9\u3092\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5\uff0e\u9ac4\u6db2\u691c\u67fb\u3068\u5168\u8eab\u691c\u7d22\uff1a\u8131\u9ac4\u75be\u60a3\u3092\u7591\u3046\u6839\u62e0<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5165\u9662\u5f8c\u3001\u8ffd\u52a0\u691c\u67fb\u304c\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u9ac4\u6db2\u691c\u67fb<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8170\u690e\u7a7f\u523a\u3067\u306f\u3001\u4ee5\u4e0b\u306e\u7d50\u679c\u304c\u5f97\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u521d\u5727\uff1a21 cmH\u2082O<\/li>\n\n\n\n<li>\u7d30\u80de\u6570\uff1a6\uff5e9\/\u03bcL<\/li>\n\n\n\n<li>\u30ea\u30f3\u30d1\u7403\u6bd4\u7387\uff1a95\uff05<\/li>\n\n\n\n<li>\u7cd6\uff1a62 mg\/dL<\/li>\n\n\n\n<li>\u7dcf\u86cb\u767d\uff1a57 mg\/dL<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u8efd\u5ea6\u306e\u30ea\u30f3\u30d1\u7403\u512a\u4f4d\u306e\u7d30\u80de\u5897\u591a\u3068\u86cb\u767d\u4e0a\u6607\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u30b0\u30e9\u30e0\u67d3\u8272\u3067\u5fae\u751f\u7269\u306f\u78ba\u8a8d\u3055\u308c\u305a\u3001\u30c8\u30ad\u30bd\u30d7\u30e9\u30ba\u30de\u6297\u4f53\u691c\u67fb\u306f\u9670\u6027\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ac4\u6db2\u7d30\u80de\u8a3a\u3067\u306f\u60aa\u6027\u7d30\u80de\u306f\u8a8d\u3081\u3089\u308c\u305a\u3001MYD88\u5909\u7570\u306e\u691c\u67fb\u3082\u9670\u6027\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">MOG\u6297\u4f53\u30fbAQP4\u6297\u4f53<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u6db2\u691c\u67fb\u3067\u306f\u3001MOG\u6297\u4f53\u304a\u3088\u3073AQP4\u6297\u4f53\u304c\u9670\u6027\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u3001MOGAD\u3084AQP4\u6297\u4f53\u967d\u6027NMOSD\u306e\u53ef\u80fd\u6027\u3092\u4f4e\u304f\u3059\u308b\u3082\u306e\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u6297\u4f53\u691c\u67fb\u9670\u6027\u306e\u307f\u3067\u3059\u3079\u3066\u306e\u95a2\u9023\u75be\u60a3\u3092\u5426\u5b9a\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u810a\u9ac4MRI\u30fbFDG-PET<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9838\u9ac4\u30fb\u80f8\u9ac4MRI\u3067\u306f\u660e\u3089\u304b\u306a\u810a\u9ac4\u75c5\u5909\u3092\u8a8d\u3081\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">FDG-PET\u3067\u306f\u3001\u5927\u8133\u767d\u8cea\u306e\u65e2\u77e5\u75c5\u5909\u306b\u4e00\u81f4\u3059\u308b\u96c6\u7a4d\u304c\u307f\u3089\u308c\u307e\u3057\u305f\u304c\u3001\u5168\u8eab\u306b\u660e\u3089\u304b\u306a\u60aa\u6027\u816b\u760d\u3092\u793a\u5506\u3059\u308b\u96c6\u7a4d\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u691c\u67fb\u3092\u7dcf\u5408\u3057\u3066\u3082\u3001\u8131\u9ac4\u75be\u60a3\u3068\u60aa\u6027\u816b\u760d\u306e\u9451\u5225\u306b\u306f\u4e0d\u78ba\u5b9f\u6027\u304c\u6b8b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u305f\u3081\u3001\u8a3a\u7642\u30c1\u30fc\u30e0\u306f\u8133\u751f\u691c\u3092\u5b9f\u65bd\u3059\u308b\u65b9\u91dd\u3068\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6\uff0e\u8133\u751f\u691c\uff1a\u9ac4\u9798\u306e\u8131\u843d\u3068\u8ef8\u7d22\u306e\u6e29\u5b58\u304c\u8a3a\u65ad\u306e\u6c7a\u3081\u624b\u306b<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u53f3\u524d\u982d\u8449\u306e\u8907\u6570\u306e\u75c5\u5909\u304b\u3089\u8133\u7d44\u7e54\u304c\u63a1\u53d6\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c5\u7406\u691c\u67fb\u3067\u306f\u3001\u4ee5\u4e0b\u306e\u6240\u898b\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 \u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306e\u8457\u660e\u306a\u6d78\u6f64<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">HE\u67d3\u8272\u3067\u306f\u3001\u75c5\u5909\u5185\u306b\u591a\u6570\u306e\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3068\u5c0f\u578b\u30ea\u30f3\u30d1\u7403\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CD68\u514d\u75ab\u67d3\u8272\u3067\u306f\u3001\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306e\u96c6\u7a4d\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u9ac4\u9798\u306e\u8131\u843d<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Luxol fast blue\u67d3\u8272\u3067\u306f\u3001\u75c5\u5909\u5185\u3067\u9ac4\u9798\u304c\u8457\u660e\u306b\u6e1b\u5c11\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Luxol fast blue\u306f\u9ac4\u9798\u3092\u67d3\u8272\u3059\u308b\u65b9\u6cd5\u3067\u3042\u308a\u3001\u8131\u9ac4\u75c5\u5909\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u7528\u3044\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u8ef8\u7d22\u306e\u76f8\u5bfe\u7684\u306a\u6e29\u5b58<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u30d5\u30a3\u30e9\u30e1\u30f3\u30c8\u306b\u5bfe\u3059\u308b\u514d\u75ab\u67d3\u8272\u3067\u306f\u3001\u9ac4\u9798\u304c\u5931\u308f\u308c\u305f\u9818\u57df\u306b\u3082\u8ef8\u7d22\u304c\u6bd4\u8f03\u7684\u4fdd\u305f\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u91cd\u8981\u306a\u6240\u898b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8131\u9ac4\u6027\u75be\u60a3\u3067\u306f\u3001\u795e\u7d4c\u7dda\u7dad\u3092\u53d6\u308a\u56f2\u3080\u9ac4\u9798\u304c\u4e3b\u306b\u969c\u5bb3\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u58ca\u6b7b\u6027\u30fb\u7834\u58ca\u6027\u75c5\u5909\u3067\u306f\u3001\u9ac4\u9798\u3060\u3051\u3067\u306a\u304f\u8ef8\u7d22\u306b\u3082\u9ad8\u5ea6\u306a\u969c\u5bb3\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u304c\u3063\u3066\u3001\u9ac4\u9798\u8131\u843d\u3068\u8ef8\u7d22\u306e\u76f8\u5bfe\u7684\u6e29\u5b58\u306e\u7d44\u307f\u5408\u308f\u305b\u306f\u3001\u8131\u9ac4\u3092\u652f\u6301\u3059\u308b\u75c5\u7406\u6240\u898b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u8131\u9ac4\u6027\u75be\u60a3\u3067\u3082\u8ef8\u7d22\u969c\u5bb3\u304c\u751f\u3058\u5f97\u308b\u305f\u3081\u3001\u300c\u8ef8\u7d22\u306f\u5b8c\u5168\u306b\u6b63\u5e38\u306b\u4fdd\u305f\u308c\u308b\u300d\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u60aa\u6027\u816b\u760d\u30fb\u8840\u7ba1\u708e\u30fb\u611f\u67d3\u75c7\u3092\u652f\u6301\u3059\u308b\u6240\u898b\u306a\u3057<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c5\u5909\u5185\u306b\u306fCD3\u967d\u6027T\u30ea\u30f3\u30d1\u7403\u304c\u4e3b\u4f53\u306e\u708e\u75c7\u7d30\u80de\u6d78\u6f64\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CD20\u967d\u6027B\u30ea\u30f3\u30d1\u7403\u306f\u5c11\u6570\u3067\u3001\u4e3b\u306b\u8840\u7ba1\u5468\u56f2\u306b\u5b58\u5728\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u60aa\u6027\u816b\u760d\u3092\u793a\u3059\u6240\u898b\u306f\u306a\u304f\u3001\u8840\u7ba1\u58c1\u3078\u306e\u708e\u75c7\u6027\u6d78\u6f64\u3084\u8840\u7ba1\u708e\u3082\u78ba\u8a8d\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001JC\u30a6\u30a4\u30eb\u30b9\u95a2\u9023\u75c5\u5909\u3092\u8a55\u4fa1\u3059\u308bSV40\u6297\u539f\u67d3\u8272\u3001\u771f\u83cc\u67d3\u8272\u3001\u305d\u306e\u4ed6\u306e\u611f\u67d3\u75c7\u95a2\u9023\u691c\u67fb\u3082\u9670\u6027\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4ee5\u4e0a\u3088\u308a\u3001\u75c5\u7406\u8a3a\u65ad\u306f\u6025\u6027\u8131\u9ac4\u6027\u75c5\u5909\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u91cd\u8981\u306a\u306e\u306f\u3001\u3053\u306e\u6bb5\u968e\u3067\u78ba\u5b9a\u3057\u305f\u306e\u306f\u300c\u8131\u9ac4\u6027\u75c5\u5909\u300d\u3067\u3042\u308a\u3001\u300c\u591a\u767a\u6027\u786c\u5316\u75c7\u300d\u3068\u3044\u3046\u75be\u60a3\u540d\u305d\u306e\u3082\u306e\u3067\u306f\u306a\u3044\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u767a\u6027\u786c\u5316\u75c7\u3001MOGAD\u3001NMOSD\u306a\u3069\u3092\u533a\u5225\u3059\u308b\u306b\u306f\u3001\u81e8\u5e8a\u7d4c\u904e\u3084\u8ffd\u52a0\u691c\u67fb\u3092\u7dcf\u5408\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"466\" height=\"600\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-27-466x600.png\" alt=\"\u8133\u751f\u691c\u306e\u75c5\u7406\u753b\u50cf\u3002CD68\u967d\u6027\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306e\u96c6\u7a4d\u3001Luxol fast blue\u67d3\u8272\u306b\u3088\u308b\u9ac4\u9798\u8131\u843d\u3001\u795e\u7d4c\u30d5\u30a3\u30e9\u30e1\u30f3\u30c8\u67d3\u8272\u306b\u3088\u308b\u8ef8\u7d22\u306e\u76f8\u5bfe\u7684\u6e29\u5b58\u3092\u793a\u3059\u3002\" class=\"wp-image-9924\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-27-466x600.png 466w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-27-233x300.png 233w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-27.png 613w\" sizes=\"auto, (max-width: 466px) 100vw, 466px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac\uff1a\u8133\u751f\u691c\u306b\u304a\u3051\u308b\u6025\u6027\u8131\u9ac4\u75c5\u5909\u306e\u75c5\u7406\u6240\u898b<\/strong>\u3002HE\u67d3\u8272\u3067\u306f\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3068\u30ea\u30f3\u30d1\u7403\u3092\u4e3b\u4f53\u3068\u3059\u308b\u708e\u75c7\u7d30\u80de\u6d78\u6f64\u3092\u8a8d\u3081\u3001CD68\u514d\u75ab\u67d3\u8272\u3067\u306f\u591a\u6570\u306e\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002Luxol fast blue\u67d3\u8272\u3067\u306f\u9ac4\u9798\u306e\u8457\u660e\u306a\u8131\u843d\u3092\u8a8d\u3081\u308b\u4e00\u65b9\u3001\u795e\u7d4c\u30d5\u30a3\u30e9\u30e1\u30f3\u30c8\u514d\u75ab\u67d3\u8272\u3067\u306f\u8ef8\u7d22\u304c\u76f8\u5bfe\u7684\u306b\u6e29\u5b58\u3055\u308c\u3066\u3044\u305f\u3002\u3053\u308c\u3089\u306e\u6240\u898b\u306f\u6025\u6027\u8131\u9ac4\u6027\u75c5\u5909\u306b\u5408\u81f4\u3059\u308b\u3002\u60aa\u6027\u816b\u760d\u3084\u8840\u7ba1\u708e\u3092\u652f\u6301\u3059\u308b\u6240\u898b\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002\u753b\u50cf\u51fa\u5178\uff1aBhattacharyya S, et al. N Engl J Med. 2026;394:2041\u20132050. DOI: 10.1056\/NEJMcpc2517865.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">7\uff0e\u6700\u7d42\u8a3a\u65ad\uff1a\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u3092\u4f34\u3046\u9ad8\u9f62\u767a\u75c7\u591a\u767a\u6027\u786c\u5316\u75c7<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u30012cm\u4ee5\u4e0a\u306e\u816b\u7624\u72b6\u8131\u9ac4\u75c5\u5909\u3092\u4f34\u3046\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\uff08tumefactive demyelination\uff09\u3068\u5224\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u306f\u3001\u753b\u50cf\u4e0a\u3001\u8133\u816b\u760d\u306b\u985e\u4f3c\u3057\u305f\u5927\u304d\u306a\u8131\u9ac4\u75c5\u5909\u3092\u5f62\u6210\u3059\u308b\u75c5\u614b\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u306f\u5358\u4e00\u306e\u75be\u60a3\u540d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u80cc\u666f\u306b\u306f\u3001\u591a\u767a\u6027\u786c\u5316\u75c7\u3001MOGAD\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u8131\u9ac4\u6027\u75be\u60a3\u304c\u5b58\u5728\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u539f\u8457\u3067\u5f15\u7528\u3055\u308c\u305f257\u4f8b\u306e\u5f8c\u308d\u5411\u304d\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u3067\u306f\u3001\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u306e\u60a3\u8005\u306e\u3046\u3061\u3001\u7d0470\uff05\u304c\u816b\u7624\u5f62\u6210\u6027MS\u30015\uff05\u304cMOGAD\u300124\uff05\u304c\u539f\u56e0\u672a\u78ba\u5b9a\u306e\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u306b\u5206\u985e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u5272\u5408\u306f\u5f53\u8a72\u30b3\u30db\u30fc\u30c8\u306e\u7d50\u679c\u3067\u3042\u308a\u3001\u3059\u3079\u3066\u306e\u60a3\u8005\u96c6\u56e3\u306b\u305d\u306e\u307e\u307e\u9069\u7528\u3067\u304d\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u9ac4\u6db2\u30aa\u30ea\u30b4\u30af\u30ed\u30fc\u30ca\u30eb\u30d0\u30f3\u30c9<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u305d\u306e\u5f8c\u3001\u9ac4\u6db2\u691c\u67fb\u30678\u672c\u306e\u9ac4\u6db2\u7279\u7570\u7684\u30aa\u30ea\u30b4\u30af\u30ed\u30fc\u30ca\u30eb\u30d0\u30f3\u30c9\uff08OCB\uff09\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305f\u3001\u9ac4\u6db2\u4e2d\u306e\u904a\u96e2\u03ba\u8efd\u9396\u3082\u4e0a\u6607\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">OCB\u306f\u3001\u4e2d\u67a2\u795e\u7d4c\u5185\u3067\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u304c\u7523\u751f\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3059\u91cd\u8981\u306a\u6307\u6a19\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u8a3a\u65ad\u3092\u652f\u6301\u3057\u307e\u3059\u304c\u3001MS\u3060\u3051\u306b\u7279\u7570\u7684\u306a\u6240\u898b\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">7T MRI\u306b\u3088\u308bcentral vein sign<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u521d\u8a3a\u304b\u3089\u7d047\u9031\u9593\u5f8c\u30017\u30c6\u30b9\u30e9MRI\u306b\u3088\u308b\u8ffd\u52a0\u8a55\u4fa1\u304c\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u75c5\u5909\u306e\u9020\u5f71\u52b9\u679c\u3084\u6d6e\u816b\u306f\u8efd\u6e1b\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3055\u3089\u306b\u3001\u591a\u6570\u306e\u6df1\u90e8\u767d\u8cea\u75c5\u5909\u304a\u3088\u3073\u8133\u5ba4\u5468\u56f2\u75c5\u5909\u306e\u5185\u90e8\u306b\u3001\u4e2d\u5fc3\u9759\u8108\u304c\u8d70\u884c\u3059\u308b\u6240\u898b\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3092central vein sign\uff08\u4e2d\u5fc3\u9759\u8108\u5fb4\u5019\uff09\u3068\u547c\u3073\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u75c5\u5909\u306f\u3001\u7d30\u3044\u9759\u8108\u306e\u5468\u56f2\u306b\u5f62\u6210\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u3001MRI\u3067\u75c5\u5909\u4e2d\u592e\u3092\u9759\u8108\u304c\u8d70\u308b\u3088\u3046\u306b\u898b\u3048\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Central vein sign\u306f\u591a\u767a\u6027\u786c\u5316\u75c7\u3092\u652f\u6301\u3059\u308b\u753b\u50cf\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u672c\u75c7\u4f8b\u3067\u306fparamagnetic rim lesion\uff08\u5e38\u78c1\u6027\u30ea\u30e0\u75c5\u5909\uff09\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"301\" height=\"591\" src=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-28.png\" alt=\"7T MRI\u306b\u3088\u308b\u5927\u8133\u767d\u8cea\u75c5\u5909\u3002\u75c5\u5909\u5185\u90e8\u3092\u4e2d\u5fc3\u9759\u8108\u304c\u8d70\u884c\u3059\u308bcentral vein sign\u304c\u8ef8\u4f4d\u65ad\u304a\u3088\u3073\u51a0\u72b6\u65ad\u3067\u793a\u3055\u308c\u3066\u3044\u308b\u3002\" class=\"wp-image-9925\" srcset=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-28.png 301w, https:\/\/kashiwa-gomi-shikanaika.com\/blog\/wp-content\/uploads\/2026\/11\/image-28-153x300.png 153w\" sizes=\"auto, (max-width: 301px) 100vw, 301px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u56f3\u8aac\uff1a\u521d\u8a3a\u304b\u3089\u7d047\u9031\u9593\u5f8c\u306b\u64ae\u5f71\u3055\u308c\u305f7T MRI<\/strong>\u3002FLAIR\u753b\u50cf\u3068T2*\u5f37\u8abf\u753b\u50cf\u3092\u91cd\u306d\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u6df1\u90e8\u767d\u8cea\u304a\u3088\u3073\u8133\u5ba4\u5468\u56f2\u767d\u8cea\u306e\u591a\u6570\u306e\u75c5\u5909\u5185\u90e8\u306b\u4e2d\u5fc3\u9759\u8108\u304c\u78ba\u8a8d\u3055\u308c\u305f\uff08\u77e2\u5370\uff09\u3002\u3053\u306ecentral vein sign\u306f\u591a\u767a\u6027\u786c\u5316\u75c7\u3092\u652f\u6301\u3059\u308b\u753b\u50cf\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3067\u3042\u308b\u3002\u672c\u75c7\u4f8b\u3067\u306f\u9ac4\u6db2\u7279\u7570\u7684\u30aa\u30ea\u30b4\u30af\u30ed\u30fc\u30ca\u30eb\u30d0\u30f3\u30c9\u306a\u3069\u306e\u6240\u898b\u3068\u5408\u308f\u305b\u3066\u8a3a\u65ad\u306b\u5bc4\u4e0e\u3057\u305f\u3002\u306a\u304a\u3001paramagnetic rim lesion\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002\u753b\u50cf\u51fa\u5178\uff1aBhattacharyya S, et al. N Engl J Med. 2026;394:2041\u20132050. DOI: 10.1056\/NEJMcpc2517865.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2024\u5e74\u6539\u8a02McDonald\u8a3a\u65ad\u57fa\u6e96<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">2024\u5e74\u6539\u8a02McDonald\u8a3a\u65ad\u57fa\u6e96\u3067\u306f\u3001\u5f93\u6765\u306e\u81e8\u5e8a\u6240\u898b\u3084MRI\u306b\u3088\u308b\u75c5\u5909\u5206\u5e03\u306b\u52a0\u3048\u3001central vein sign\u3001paramagnetic rim lesion\u3001\u9ac4\u6db2\u904a\u96e2\u03ba\u8efd\u9396\u306a\u3069\u304c\u8a3a\u65ad\u3092\u652f\u6301\u3059\u308b\u6240\u898b\u3068\u3057\u3066\u7d44\u307f\u8fbc\u307e\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u6240\u898b\u306f\u5358\u72ec\u3067\u4e00\u5f8b\u306bMS\u3092\u78ba\u5b9a\u3059\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u8a3a\u65ad\u57fa\u6e96\u3067\u5b9a\u3081\u3089\u308c\u305f\u6761\u4ef6\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u89e3\u91c8\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u81e8\u5e8a\u7d4c\u904e<\/li>\n\n\n\n<li>\u591a\u767a\u6027\u767d\u8cea\u75c5\u5909<\/li>\n\n\n\n<li>\u8133\u751f\u691c\u306b\u3088\u308b\u8131\u9ac4\u306e\u78ba\u8a8d<\/li>\n\n\n\n<li>MOG\u6297\u4f53\u30fbAQP4\u6297\u4f53\u9670\u6027<\/li>\n\n\n\n<li>\u9ac4\u6db2\u7279\u7570\u7684OCB\u967d\u6027<\/li>\n\n\n\n<li>Central vein sign\u967d\u6027<\/li>\n\n\n\n<li>\u816b\u760d\u30fb\u611f\u67d3\u75c7\u306a\u3069\u306e\u4ee3\u66ff\u8a3a\u65ad\u3092\u652f\u6301\u3059\u308b\u6240\u898b\u304c\u306a\u3044\u3053\u3068<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u3092\u7dcf\u5408\u3057\u30012024\u5e74\u6539\u8a02McDonald\u8a3a\u65ad\u57fa\u6e96\u306b\u57fa\u3065\u3044\u3066\u591a\u767a\u6027\u786c\u5316\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">8\uff0e\u6cbb\u7642\uff1a\u30b9\u30c6\u30ed\u30a4\u30c9\u30d1\u30eb\u30b9\u7642\u6cd5\u304b\u3089\u6297CD20\u6297\u4f53\u3078<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u816b\u7624\u5f62\u6210\u6027\u8131\u9ac4\u306e\u6025\u6027\u671f\u6cbb\u7642\u3067\u306f\u3001\u9ad8\u7528\u91cf\u306e\u9759\u6ce8\u30e1\u30c1\u30eb\u30d7\u30ec\u30c9\u30cb\u30be\u30ed\u30f3\u304c\u7b2c\u4e00\u9078\u629e\u3068\u3057\u3066\u7528\u3044\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u3082\u30b9\u30c6\u30ed\u30a4\u30c9\u6cbb\u7642\u5f8c\u306b\u795e\u7d4c\u75c7\u72b6\u304c\u6539\u5584\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u91cd\u75c7\u4f8b\u3084\u30b9\u30c6\u30ed\u30a4\u30c9\u53cd\u5fdc\u4e0d\u5341\u5206\u4f8b\u3067\u306f\u3001\u8840\u6f3f\u4ea4\u63db\u7642\u6cd5\u306a\u3069\u304c\u691c\u8a0e\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u6cbb\u7642\u9078\u629e\u306f\u75c5\u5909\u306e\u91cd\u75c7\u5ea6\u3001\u539f\u56e0\u75be\u60a3\u3001\u81e8\u5e8a\u7d4c\u904e\u306b\u5fdc\u3058\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u9ad8\u9f62\u767a\u75c7MS\u306b\u304a\u3051\u308b\u6cbb\u7642\u9078\u629e<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306f\u82e5\u5e74\u6210\u4eba\u306b\u591a\u3044\u75be\u60a3\u3067\u3059\u304c\u300150\u6b73\u4ee5\u964d\u306b\u767a\u75c7\u3059\u308b\u75c7\u4f8b\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u539f\u8457\u3067\u306f\u300160\u6b73\u3092\u8d85\u3048\u3066\u8a3a\u65ad\u3055\u308c\u308bMS\u75c7\u4f8b\u306f\u7d041\uff05\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u9f62\u767a\u75c7MS\u3067\u306f\u3001\u82e5\u5e74\u767a\u75c7\u4f8b\u3068\u6bd4\u8f03\u3057\u3066\u904b\u52d5\u969c\u5bb3\u304c\u76ee\u7acb\u3061\u3001\u9032\u884c\u6027\u306e\u7d4c\u904e\u3092\u793a\u3059\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3001\u9ad8\u9f62\u60a3\u8005\u3067\u306f\u514d\u75ab\u8001\u5316\u3084\u4f75\u5b58\u75be\u60a3\u306b\u3088\u308a\u3001\u514d\u75ab\u6291\u5236\u30fb\u514d\u75ab\u8abf\u6574\u7642\u6cd5\u306b\u4f34\u3046\u611f\u67d3\u75c7\u30ea\u30b9\u30af\u306b\u3082\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u4f8b\u3067\u306f\u3001\u75c5\u5909\u306e\u591a\u3055\u3068\u75be\u60a3\u6d3b\u52d5\u6027\u3092\u8003\u616e\u3057\u3001\u60a3\u8005\u3068\u5341\u5206\u306b\u8a71\u3057\u5408\u3063\u305f\u3046\u3048\u3067\u3001\u9ad8\u52b9\u529b\u306e\u75be\u60a3\u4fee\u98fe\u85ac\u3092\u9078\u629e\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f7f\u7528\u3055\u308c\u305f\u306e\u306f\u3001\u6297CD20\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3067\u3042\u308bublituximab\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6297CD20\u6297\u4f53\u306fB\u7d30\u80de\u3092\u6a19\u7684\u3068\u3057\u3001\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u708e\u75c7\u6d3b\u52d5\u6027\u3092\u6291\u5236\u3059\u308b\u6cbb\u7642\u85ac\u3067\u3059\u3002<\/p>\n\n\n\n<p 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rel=\"noopener\">\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u306e\u6700\u65b0\u8a3a\u65ad\u3068\u6cbb\u76422026\uff5c\u5168\u8eab\u6027\u8089\u82bd\u816b\u6027\u75be\u60a3\u306e\u75c5\u614b\u3068\u81d3\u5668\u969c\u5bb3<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u3067\u306f\u795e\u7d4c\u75c5\u5909\u304c\u521d\u767a\u75c7\u72b6\u3068\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u4e2d\u67a2\u795e\u7d4c\u306e\u708e\u75c7\u6027\u75be\u60a3\u3092\u9451\u5225\u3059\u308b\u3046\u3048\u3067\u91cd\u8981\u306a\u5168\u8eab\u6027\u75be\u60a3\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u2462 <a href=\"https:\/\/kashiwa-gomi-shikanaika.com\/blog\/post-9391\/\" target=\"_blank\" rel=\"noopener\">\u8133\u30a2\u30df\u30ed\u30a4\u30c9\u30a2\u30f3\u30ae\u30aa\u30d1\u30c1\u30fc\uff08CAA\uff09\uff5cMRI\u3067500\u500b\u8d85\u306e\u5fae\u5c0f\u51fa\u8840\u3092\u8a8d\u3081\u305f\u75c7\u4f8b<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3084\u6b69\u884c\u969c\u5bb3\u3092\u5951\u6a5f\u3068\u3057\u3066\u767a\u898b\u3055\u308c\u305f\u3001\u5225\u306e\u795e\u7d4c\u75be\u60a3\u306e\u75c7\u4f8b\u3067\u3059\u3002MRI\u6240\u898b\u3092\u75c5\u614b\u751f\u7406\u3068\u7d50\u3073\u3064\u3051\u3066\u8003\u3048\u308b\u3046\u3048\u3067\u53c2\u8003\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h3>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph\">1. Bhattacharyya S, Cartmell SCD, Hung AY, Bilodeau PA, Conner EC. Case 15-2026: A 64-Year-Old Woman with Fatigue, Memory Changes, and Falls. N Engl J Med. 2026;394:2041\u20132050.<br><a href=\"https:\/\/doi.org\/10.1056\/NEJMcpc2517865\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1056\/NEJMcpc2517865<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2. Montalban X, Lebrun-Fr\u00e9nay C, Oh J, et al. Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Lancet Neurol. 2025;24:850\u2013865.<br><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40975101\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/40975101\/<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">3. Suh CH, Kim HS, Jung SC, Choi CG, Kim SJ. MRI Findings in Tumefactive Demyelinating Lesions: A Systematic Review and Meta-Analysis. AJNR Am J Neuroradiol. 2018;39:1643\u20131649.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">4. Fereidan-Esfahani M, Decker PA, Weigand SD, et al. Defining the Natural History of Tumefactive Demyelination: A Retrospective Cohort of 257 Patients. Ann Clin Transl Neurol. 2023;10:1544\u20131555.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">5. Jakimovski D, Bittner S, Zivadinov R, et al. Multiple sclerosis. Lancet. 2024;403:183\u2013202.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">6. Naseri A, Nasiri E, Sahraian MA, Daneshvar S, Talebi M. Clinical features of late-onset multiple sclerosis: a systematic review and meta-analysis. 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